Result of FASTA (omim) for
pFN21AE6673
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6673, 309 aa
1>>>pF1KE6673 309 - 309 aa - 309 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3672+/-0.00031; mu= 16.7994+/- 0.019
mean_var=84.6775+/-16.968, 0's: 0 Z-trim(116.7): 92 B-trim: 0 in 0/51
Lambda= 0.139377
statistics sampled from 29045 (29140) to 29045 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.318), width: 16
Scan time: 3.420
The best scores are: opt bits E(91774)
NP_004359 (OMIM: 602373) calponin-2 isoform a [Hom ( 309) 2108 433.3 3.1e-121
NP_001830 (OMIM: 602374) calponin-3 isoform 1 [Hom ( 329) 1324 275.7 9.4e-74
NP_001290428 (OMIM: 602373) calponin-2 isoform c [ ( 298) 1258 262.4 8.6e-70
NP_001290430 (OMIM: 602373) calponin-2 isoform d [ ( 330) 1254 261.6 1.6e-69
NP_001290 (OMIM: 600806) calponin-1 isoform 1 [Hom ( 297) 1217 254.2 2.6e-67
XP_016855734 (OMIM: 602374) calponin-3 isoform X1 ( 288) 1129 236.5 5.4e-62
NP_001272985 (OMIM: 602374) calponin-3 isoform 3 [ ( 288) 1129 236.5 5.4e-62
XP_024307130 (OMIM: 600806) calponin-1 isoform X2 ( 299) 1104 231.4 1.8e-60
XP_024307129 (OMIM: 600806) calponin-1 isoform X2 ( 299) 1104 231.4 1.8e-60
XP_016881778 (OMIM: 600806) calponin-1 isoform X1 ( 363) 1104 231.5 2.1e-60
NP_958434 (OMIM: 602373) calponin-2 isoform b [Hom ( 270) 1010 212.5 8.2e-55
NP_001295270 (OMIM: 600806) calponin-1 isoform 2 [ ( 247) 985 207.4 2.5e-53
NP_001295271 (OMIM: 600806) calponin-1 isoform 2 [ ( 247) 985 207.4 2.5e-53
XP_005259798 (OMIM: 600806) calponin-1 isoform X3 ( 247) 985 207.4 2.5e-53
NP_001272984 (OMIM: 602374) calponin-3 isoform 2 [ ( 283) 736 157.4 3.3e-38
NP_001264152 (OMIM: 604634) transgelin-2 isoform b ( 199) 390 87.7 2.2e-17
NP_003555 (OMIM: 604634) transgelin-2 isoform b [H ( 199) 390 87.7 2.2e-17
NP_001264153 (OMIM: 604634) transgelin-2 isoform a ( 220) 390 87.8 2.4e-17
NP_037391 (OMIM: 607953) transgelin-3 [Homo sapien ( 199) 373 84.3 2.4e-16
NP_001008274 (OMIM: 607953) transgelin-3 [Homo sap ( 199) 373 84.3 2.4e-16
NP_001008273 (OMIM: 607953) transgelin-3 [Homo sap ( 199) 373 84.3 2.4e-16
NP_001001522 (OMIM: 600818) transgelin [Homo sapie ( 201) 323 74.3 2.5e-13
NP_003177 (OMIM: 600818) transgelin [Homo sapiens] ( 201) 323 74.3 2.5e-13
NP_001317713 (OMIM: 617750) LIM and calponin homol ( 980) 212 52.5 4.3e-06
NP_001317718 (OMIM: 617750) LIM and calponin homol (1029) 212 52.5 4.5e-06
NP_001317721 (OMIM: 617750) LIM and calponin homol (1044) 212 52.5 4.5e-06
NP_001317717 (OMIM: 617750) LIM and calponin homol (1055) 212 52.5 4.6e-06
NP_001106189 (OMIM: 617750) LIM and calponin homol (1056) 212 52.5 4.6e-06
NP_001106188 (OMIM: 617750) LIM and calponin homol (1057) 212 52.5 4.6e-06
XP_016863389 (OMIM: 617750) LIM and calponin homol (1058) 212 52.5 4.6e-06
NP_001276051 (OMIM: 617750) LIM and calponin homol (1069) 212 52.5 4.6e-06
NP_001317720 (OMIM: 617750) LIM and calponin homol (1070) 212 52.5 4.6e-06
XP_024309705 (OMIM: 617750) LIM and calponin homol (1074) 212 52.5 4.6e-06
NP_001317719 (OMIM: 617750) LIM and calponin homol (1082) 212 52.5 4.7e-06
NP_055803 (OMIM: 617750) LIM and calponin homology (1083) 212 52.5 4.7e-06
NP_001317716 (OMIM: 617750) LIM and calponin homol (1085) 212 52.6 4.7e-06
XP_016863387 (OMIM: 617750) LIM and calponin homol (1086) 212 52.6 4.7e-06
XP_011511956 (OMIM: 617750) LIM and calponin homol (1099) 212 52.6 4.7e-06
XP_011511955 (OMIM: 617750) LIM and calponin homol (1111) 212 52.6 4.7e-06
XP_016863386 (OMIM: 617750) LIM and calponin homol (1573) 212 52.7 6.2e-06
XP_011511950 (OMIM: 617750) LIM and calponin homol (1574) 212 52.7 6.2e-06
XP_016863385 (OMIM: 617750) LIM and calponin homol (1598) 212 52.7 6.2e-06
XP_006714059 (OMIM: 617750) LIM and calponin homol (1600) 212 52.7 6.2e-06
XP_005248118 (OMIM: 617750) LIM and calponin homol (1602) 212 52.7 6.2e-06
XP_011511948 (OMIM: 617750) LIM and calponin homol (1626) 212 52.7 6.3e-06
XP_005248117 (OMIM: 617750) LIM and calponin homol (1626) 212 52.7 6.3e-06
XP_011511947 (OMIM: 617750) LIM and calponin homol (1627) 212 52.7 6.3e-06
XP_016863384 (OMIM: 617750) LIM and calponin homol (1627) 212 52.7 6.3e-06
XP_005248115 (OMIM: 617750) LIM and calponin homol (1629) 212 52.7 6.3e-06
XP_005248114 (OMIM: 617750) LIM and calponin homol (1630) 212 52.7 6.3e-06
>>NP_004359 (OMIM: 602373) calponin-2 isoform a [Homo sa (309 aa)
initn: 2108 init1: 2108 opt: 2108 Z-score: 2298.0 bits: 433.3 E(91774): 3.1e-121
Smith-Waterman score: 2108; 100.0% identity (100.0% similar) in 309 aa overlap (1-309:1-309)
10 20 30 40 50 60
pF1KE6 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 DNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEYP
250 260 270 280 290 300
pF1KE6 PYYQEEAGY
:::::::::
NP_004 PYYQEEAGY
>>NP_001830 (OMIM: 602374) calponin-3 isoform 1 [Homo sa (329 aa)
initn: 1503 init1: 1201 opt: 1324 Z-score: 1445.7 bits: 275.7 E(91774): 9.4e-74
Smith-Waterman score: 1324; 65.5% identity (81.6% similar) in 310 aa overlap (4-306:2-311)
10 20 30 40 50 60
pF1KE6 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL
:.:::::::::::::::.. :::: : : .::.::: .::.::::.:: ::::: ::
NP_001 MTHFNKGPSYGLSAEVKNKIASKYDHQAEEDLRNWIEEVTGMSIGPNFQLGLKDGIIL
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV
: :.:::::::: :.:.: :: ::::..:::::. .:::.: :.::::::::.::::::
NP_001 CELINKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 QVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSG
:..:.:::: :::::... .::::::.::: : ::.. .:::: ::::::::::::::.:
NP_001 QTTLVALAGLAKTKGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAG
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC
:::::::::::::: . :.:..:::::::::: :::.:: :::::: ::: :: .
NP_001 MTAYGTRRHLYDPKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPV
180 190 200 210 220 230
250 260 270 280 290
pF1KE6 DNSSMSLQMGYTQGANQSGQ-VFGLGRQIYDPKYC--PQGTVADGAPSGTG----DCPDP
:::..::::: .. :.:.:. :.:::::.:::::: : : .. .::: . :
NP_001 DNSTISLQMGTNKVASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDS
240 250 260 270 280 290
300
pF1KE6 GEVPEYPPYYQEEAGY
::: :. :
NP_001 DYQAEYPDEYHGEYQDDYPRDYQYSDQGIDY
300 310 320
>>NP_001290428 (OMIM: 602373) calponin-2 isoform c [Homo (298 aa)
initn: 1254 init1: 1254 opt: 1258 Z-score: 1374.5 bits: 262.4 E(91774): 8.6e-70
Smith-Waterman score: 2015; 96.4% identity (96.4% similar) in 309 aa overlap (1-309:1-298)
10 20 30 40 50 60
pF1KE6 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQ-
70 80 90 100 110
130 140 150 160 170 180
pF1KE6 QVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSG
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------AKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSG
120 130 140 150 160
190 200 210 220 230 240
pF1KE6 MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE6 DNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEYP
230 240 250 260 270 280
pF1KE6 PYYQEEAGY
:::::::::
NP_001 PYYQEEAGY
290
>>NP_001290430 (OMIM: 602373) calponin-2 isoform d [Homo (330 aa)
initn: 1254 init1: 1254 opt: 1254 Z-score: 1369.6 bits: 261.6 E(91774): 1.6e-69
Smith-Waterman score: 2056; 93.6% identity (93.6% similar) in 330 aa overlap (1-309:1-330)
10 20 30 40 50 60
pF1KE6 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV
70 80 90 100 110 120
130 140 150
pF1KE6 QVSLLALAGK---------------------AKTKGLQSGVDIGVKYSEKQERNFDDATM
:::::::::: :::::::::::::::::::::::::::::
NP_001 QVSLLALAGKGLDLGSLAALCWYSRPLSLTQAKTKGLQSGVDIGVKYSEKQERNFDDATM
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 KAGQCVIGLQMGTNKCASQSGMTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAGQCVIGLQMGTNKCASQSGMTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE6 GMTAPGTRRHIYDTKLGTDKCDNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMTAPGTRRHIYDTKLGTDKCDNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTV
250 260 270 280 290 300
280 290 300
pF1KE6 ADGAPSGTGDCPDPGEVPEYPPYYQEEAGY
::::::::::::::::::::::::::::::
NP_001 ADGAPSGTGDCPDPGEVPEYPPYYQEEAGY
310 320 330
>>NP_001290 (OMIM: 600806) calponin-1 isoform 1 [Homo sa (297 aa)
initn: 1449 init1: 636 opt: 1217 Z-score: 1330.0 bits: 254.2 E(91774): 2.6e-67
Smith-Waterman score: 1217; 65.8% identity (85.8% similar) in 275 aa overlap (1-274:1-273)
10 20 30 40 50 60
pF1KE6 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTIL
:::..::.::.:::::::::.: .::: :.: ::: ::::.:: :: .:. ::::: ::
NP_001 MSSAHFNRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGNNFMDGLKDGIIL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 CTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQV
: ..:::::::: :::.: ::::::::..:::::...::..: :.::::::::. : :::
NP_001 CEFINKLQPGSVKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSG
: .:::::. ::::: . :..::::.:::::.:. . .. :. .::::::::: :::.:
NP_001 QSTLLALASMAKTKG--NKVNVGVKYAEKQERKFEPGKLREGRNIIGLQMGTNKFASQQG
130 140 150 160 170
190 200 210 220 230 240
pF1KE6 MTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKC
:::::::::::::: :.:..:::::::::: :::.:::::::.:.:.. :: ..:
NP_001 MTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGMEHC
180 190 200 210 220 230
250 260 270 280 290
pF1KE6 DNSSMSLQMGYTQGANQSGQ-VFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEY
:. ..::::: ..::.: :. :.:: ::.::::::
NP_001 DTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYPELGEPAHNHHAHNYYNSA
240 250 260 270 280 290
300
pF1KE6 PPYYQEEAGY
>>XP_016855734 (OMIM: 602374) calponin-3 isoform X1 [Hom (288 aa)
initn: 1311 init1: 1009 opt: 1129 Z-score: 1234.6 bits: 236.5 E(91774): 5.4e-62
Smith-Waterman score: 1129; 64.4% identity (80.7% similar) in 270 aa overlap (44-306:1-270)
20 30 40 50 60 70
pF1KE6 LSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTILCTLMNKLQPGSVP
.::::.:: ::::: ::: :.::::::::
XP_016 MSIGPNFQLGLKDGIILCELINKLQPGSVK
10 20 30
80 90 100 110 120 130
pF1KE6 KINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKAKT
:.:.: :: ::::..:::::. .:::.: :.::::::::.:::::::..:.:::: :::
XP_016 KVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKT
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE6 KGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSGMTAYGTRRHLYDP
::... .::::::.::: : ::.. .:::: ::::::::::::::.::::::::::::::
XP_016 KGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDP
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE6 KNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKCDNSSMSLQMGYTQ
: . :.:..:::::::::: :::.:: :::::: ::: :: . :::..::::: ..
XP_016 KMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNSTISLQMGTNK
160 170 180 190 200 210
260 270 280 290 300
pF1KE6 GANQSGQ-VFGLGRQIYDPKYC--PQGTVADGAPSGTG----DCPDPGEVPEYPPYYQEE
:.:.:. :.:::::.:::::: : : .. .::: . : ::: :. :
XP_016 VASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQAEYPDEYHGE
220 230 240 250 260 270
pF1KE6 AGY
XP_016 YQDDYPRDYQYSDQGIDY
280
>>NP_001272985 (OMIM: 602374) calponin-3 isoform 3 [Homo (288 aa)
initn: 1311 init1: 1009 opt: 1129 Z-score: 1234.6 bits: 236.5 E(91774): 5.4e-62
Smith-Waterman score: 1129; 64.4% identity (80.7% similar) in 270 aa overlap (44-306:1-270)
20 30 40 50 60 70
pF1KE6 LSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGTILCTLMNKLQPGSVP
.::::.:: ::::: ::: :.::::::::
NP_001 MSIGPNFQLGLKDGIILCELINKLQPGSVK
10 20 30
80 90 100 110 120 130
pF1KE6 KINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKAKT
:.:.: :: ::::..:::::. .:::.: :.::::::::.:::::::..:.:::: :::
NP_001 KVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKT
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE6 KGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSGMTAYGTRRHLYDP
::... .::::::.::: : ::.. .:::: ::::::::::::::.::::::::::::::
NP_001 KGFHTTIDIGVKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYDP
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE6 KNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTDKCDNSSMSLQMGYTQ
: . :.:..:::::::::: :::.:: :::::: ::: :: . :::..::::: ..
NP_001 KMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNSTISLQMGTNK
160 170 180 190 200 210
260 270 280 290 300
pF1KE6 GANQSGQ-VFGLGRQIYDPKYC--PQGTVADGAPSGTG----DCPDPGEVPEYPPYYQEE
:.:.:. :.:::::.:::::: : : .. .::: . : ::: :. :
NP_001 VASQKGMSVYGLGRQVYDPKYCAAPTEPVIHNGSQGTGTNGSEISDSDYQAEYPDEYHGE
220 230 240 250 260 270
pF1KE6 AGY
NP_001 YQDDYPRDYQYSDQGIDY
280
>>XP_024307130 (OMIM: 600806) calponin-1 isoform X2 [Hom (299 aa)
initn: 1333 init1: 529 opt: 1104 Z-score: 1207.2 bits: 231.4 E(91774): 1.8e-60
Smith-Waterman score: 1104; 65.0% identity (84.6% similar) in 254 aa overlap (22-274:24-275)
10 20 30 40 50
pF1KE6 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGT
: .::: :.: ::: ::::.:: :: .:. :::::
XP_024 MTSTPLQASTQGHLLRHPSSLPELAQKYDHQREQELREWIEGVTGRRIGNNFMDGLKDGI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 ILCTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMT
::: ..:::::::: :::.: ::::::::..:::::...::..: :.::::::::. : :
XP_024 ILCEFINKLQPGSVKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 QVQVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQ
::: .:::::. ::::: . :..::::.:::::.:. . .. :. .::::::::: :::
XP_024 QVQSTLLALASMAKTKG--NKVNVGVKYAEKQERKFEPGKLREGRNIIGLQMGTNKFASQ
130 140 150 160 170
180 190 200 210 220 230
pF1KE6 SGMTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTD
.::::::::::::::: :.:..:::::::::: :::.:::::::.:.:.. :: .
XP_024 QGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGME
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 KCDNSSMSLQMGYTQGANQSGQ-VFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVP
.::. ..::::: ..::.: :. :.:: ::.::::::
XP_024 HCDTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYPELGEPAHNHHAHNYYNS
240 250 260 270 280 290
300
pF1KE6 EYPPYYQEEAGY
XP_024 A
>>XP_024307129 (OMIM: 600806) calponin-1 isoform X2 [Hom (299 aa)
initn: 1333 init1: 529 opt: 1104 Z-score: 1207.2 bits: 231.4 E(91774): 1.8e-60
Smith-Waterman score: 1104; 65.0% identity (84.6% similar) in 254 aa overlap (22-274:24-275)
10 20 30 40 50
pF1KE6 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQKGLKDGT
: .::: :.: ::: ::::.:: :: .:. :::::
XP_024 MTSTPLQASTQGHLLRHPSSLPELAQKYDHQREQELREWIEGVTGRRIGNNFMDGLKDGI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 ILCTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMT
::: ..:::::::: :::.: ::::::::..:::::...::..: :.::::::::. : :
XP_024 ILCEFINKLQPGSVKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 QVQVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQ
::: .:::::. ::::: . :..::::.:::::.:. . .. :. .::::::::: :::
XP_024 QVQSTLLALASMAKTKG--NKVNVGVKYAEKQERKFEPGKLREGRNIIGLQMGTNKFASQ
130 140 150 160 170
180 190 200 210 220 230
pF1KE6 SGMTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLGTD
.::::::::::::::: :.:..:::::::::: :::.:::::::.:.:.. :: .
XP_024 QGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIFEPGLGME
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 KCDNSSMSLQMGYTQGANQSGQ-VFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVP
.::. ..::::: ..::.: :. :.:: ::.::::::
XP_024 HCDTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYPELGEPAHNHHAHNYYNS
240 250 260 270 280 290
300
pF1KE6 EYPPYYQEEAGY
XP_024 A
>>XP_016881778 (OMIM: 600806) calponin-1 isoform X1 [Hom (363 aa)
initn: 1333 init1: 529 opt: 1104 Z-score: 1206.0 bits: 231.5 E(91774): 2.1e-60
Smith-Waterman score: 1104; 65.0% identity (84.6% similar) in 254 aa overlap (22-274:88-339)
10 20 30 40 50
pF1KE6 MSSTQFNKGPSYGLSAEVKNRLLSKYDPQKEAELRTWIEGLTGLSIGPDFQ
: .::: :.: ::: ::::.:: :: .:.
XP_016 DTERQRCMTSTPLQASTQGHLLRHPSSLPELAQKYDHQREQELREWIEGVTGRRIGNNFM
60 70 80 90 100 110
60 70 80 90 100 110
pF1KE6 KGLKDGTILCTLMNKLQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDL
::::: ::: ..:::::::: :::.: ::::::::..:::::...::..: :.::::::
XP_016 DGLKDGIILCEFINKLQPGSVKKINESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDL
120 130 140 150 160 170
120 130 140 150 160 170
pF1KE6 FESGNMTQVQVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMG
::. : :::: .:::::. ::::: . :..::::.:::::.:. . .. :. .::::::
XP_016 FENTNHTQVQSTLLALASMAKTKG--NKVNVGVKYAEKQERKFEPGKLREGRNIIGLQMG
180 190 200 210 220 230
180 190 200 210 220 230
pF1KE6 TNKCASQSGMTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIY
::: :::.::::::::::::::: :.:..:::::::::: :::.:::::::.:.:.
XP_016 TNKFASQQGMTAYGTRRHLYDPKLGTDQPLDQATISLQMGTNKGASQAGMTAPGTKRQIF
240 250 260 270 280 290
240 250 260 270 280 290
pF1KE6 DTKLGTDKCDNSSMSLQMGYTQGANQSGQ-VFGLGRQIYDPKYCPQGTVADGAPSGTGDC
. :: ..::. ..::::: ..::.: :. :.:: ::.::::::
XP_016 EPGLGMEHCDTLNVSLQMGSNKGASQRGMTVYGLPRQVYDPKYCLTPEYPELGEPAHNHH
300 310 320 330 340 350
300
pF1KE6 PDPGEVPEYPPYYQEEAGY
XP_016 AHNYYNSA
360
309 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Jul 16 16:09:19 2019 done: Tue Jul 16 16:09:19 2019
Total Scan time: 3.420 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]