Result of FASTA (omim) for
pFN21AE2479
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2479, 848 aa
1>>>pF1KE2479 848 - 848 aa - 848 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9656+/-0.000582; mu= 17.9815+/- 0.036
mean_var=104.6252+/-21.036, 0's: 0 Z-trim(109.0): 183 B-trim: 251 in 1/49
Lambda= 0.125388
statistics sampled from 16953 (17136) to 16953 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.546), E-opt: 0.2 (0.201), width: 16
Scan time: 8.910
The best scores are: opt bits E(85289)
NP_003296 (OMIM: 602345,616410) short transient re ( 848) 5556 1017.1 0
NP_001124170 (OMIM: 602345,616410) short transient ( 921) 5556 1017.2 0
XP_011530520 (OMIM: 602345,616410) PREDICTED: shor ( 920) 5537 1013.7 0
XP_016864067 (OMIM: 602345,616410) PREDICTED: shor ( 936) 4936 905.0 0
XP_011530519 (OMIM: 602345,616410) PREDICTED: shor ( 937) 4931 904.1 0
XP_016864068 (OMIM: 602345,616410) PREDICTED: shor ( 893) 4930 903.9 0
XP_011541270 (OMIM: 603652,603965) PREDICTED: shor ( 876) 3832 705.3 3.1e-202
NP_004612 (OMIM: 603652,603965) short transient re ( 931) 3832 705.3 3.2e-202
XP_016873711 (OMIM: 603652,603965) PREDICTED: shor ( 845) 3730 686.8 1.1e-196
XP_016873710 (OMIM: 603652,603965) PREDICTED: shor ( 815) 1822 341.7 8.4e-93
NP_001129428 (OMIM: 603651) short transient recept ( 828) 803 157.3 2.6e-37
NP_001129429 (OMIM: 603651) short transient recept ( 836) 803 157.3 2.6e-37
NP_001129427 (OMIM: 603651) short transient recept ( 893) 803 157.4 2.8e-37
NP_057263 (OMIM: 603651) short transient receptor ( 977) 803 157.4 3e-37
NP_003297 (OMIM: 603651) short transient receptor ( 982) 803 157.4 3e-37
NP_036603 (OMIM: 300334) short transient receptor ( 973) 786 154.3 2.5e-36
XP_016885263 (OMIM: 300334) PREDICTED: short trans ( 973) 786 154.3 2.5e-36
XP_005247796 (OMIM: 602343) PREDICTED: short trans ( 661) 747 147.1 2.5e-34
XP_005247795 (OMIM: 602343) PREDICTED: short trans ( 695) 747 147.1 2.6e-34
XP_016862611 (OMIM: 602343) PREDICTED: short trans ( 709) 747 147.1 2.6e-34
XP_016862610 (OMIM: 602343) PREDICTED: short trans ( 732) 747 147.2 2.7e-34
NP_003295 (OMIM: 602343) short transient receptor ( 759) 747 147.2 2.7e-34
NP_001238774 (OMIM: 602343) short transient recept ( 793) 747 147.2 2.8e-34
XP_011533508 (OMIM: 603651) PREDICTED: short trans ( 562) 488 100.2 2.8e-20
XP_016876212 (OMIM: 603651) PREDICTED: short trans ( 562) 488 100.2 2.8e-20
XP_016876213 (OMIM: 603651) PREDICTED: short trans ( 557) 483 99.3 5.2e-20
NP_001129430 (OMIM: 603651) short transient recept ( 804) 483 99.4 6.8e-20
XP_016869778 (OMIM: 602014,607009) PREDICTED: tran (1560) 225 53.0 1.3e-05
XP_011516554 (OMIM: 602014,607009) PREDICTED: tran (1694) 225 53.0 1.3e-05
XP_011516553 (OMIM: 602014,607009) PREDICTED: tran (1779) 225 53.0 1.4e-05
XP_011516551 (OMIM: 602014,607009) PREDICTED: tran (1944) 225 53.1 1.5e-05
XP_011516550 (OMIM: 602014,607009) PREDICTED: tran (1975) 225 53.1 1.5e-05
XP_011516548 (OMIM: 602014,607009) PREDICTED: tran (1981) 225 53.1 1.5e-05
XP_011516547 (OMIM: 602014,607009) PREDICTED: tran (1991) 225 53.1 1.5e-05
NP_001170781 (OMIM: 602014,607009) transient recep (2017) 225 53.1 1.5e-05
NP_001170782 (OMIM: 602014,607009) transient recep (2017) 225 53.1 1.5e-05
XP_011516546 (OMIM: 602014,607009) PREDICTED: tran (2021) 225 53.1 1.5e-05
NP_060132 (OMIM: 602014,607009) transient receptor (2022) 225 53.1 1.5e-05
XP_011516557 (OMIM: 602014,607009) PREDICTED: tran (1184) 221 52.2 1.7e-05
XP_016869777 (OMIM: 602014,607009) PREDICTED: tran (1852) 219 52.0 3e-05
XP_011516552 (OMIM: 602014,607009) PREDICTED: tran (1930) 219 52.0 3.1e-05
XP_016869776 (OMIM: 602014,607009) PREDICTED: tran (1901) 216 51.4 4.5e-05
XP_011516549 (OMIM: 602014,607009) PREDICTED: tran (1979) 216 51.5 4.6e-05
XP_016877844 (OMIM: 105500,605692) PREDICTED: tran (1826) 205 49.4 0.00017
XP_016877843 (OMIM: 105500,605692) PREDICTED: tran (1826) 205 49.4 0.00017
NP_001288141 (OMIM: 105500,605692) transient recep (1864) 205 49.4 0.00018
NP_060142 (OMIM: 105500,605692) transient receptor (1865) 205 49.4 0.00018
XP_016877842 (OMIM: 105500,605692) PREDICTED: tran (1873) 205 49.4 0.00018
XP_016877841 (OMIM: 105500,605692) PREDICTED: tran (1874) 205 49.4 0.00018
XP_005254543 (OMIM: 105500,605692) PREDICTED: tran (1885) 205 49.4 0.00018
>>NP_003296 (OMIM: 602345,616410) short transient recept (848 aa)
initn: 5556 init1: 5556 opt: 5556 Z-score: 5437.4 bits: 1017.1 E(85289): 0
Smith-Waterman score: 5556; 100.0% identity (100.0% similar) in 848 aa overlap (1-848:1-848)
10 20 30 40 50 60
pF1KE2 MEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 MKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 RHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITVT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 DYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSIF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 IAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISEG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILYS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 YYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMVV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 VLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYFI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 MRIVNFPKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MRIVNFPKCRRRRLQKDIEMGMGNSKSRLNLFTQSNSRVFESHSFNSILNQPTRYQQIMK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 RLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKL
790 800 810 820 830 840
pF1KE2 NPSMLRCE
::::::::
NP_003 NPSMLRCE
>>NP_001124170 (OMIM: 602345,616410) short transient rec (921 aa)
initn: 5556 init1: 5556 opt: 5556 Z-score: 5436.9 bits: 1017.2 E(85289): 0
Smith-Waterman score: 5556; 100.0% identity (100.0% similar) in 848 aa overlap (1-848:74-921)
10 20 30
pF1KE2 MEGSPSLRRMTVMREKGRRQAVRGPAFMFN
::::::::::::::::::::::::::::::
NP_001 NGGLEPRSAPSQREPHGYCPPPFSHGPDLSMEGSPSLRRMTVMREKGRRQAVRGPAFMFN
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE2 DRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVT
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE2 ELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAY
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE2 DEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSH
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE2 SRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFV
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE2 VGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQL
350 360 370 380 390 400
340 350 360 370 380 390
pF1KE2 LTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHA
410 420 430 440 450 460
400 410 420 430 440 450
pF1KE2 ASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMW
470 480 490 500 510 520
460 470 480 490 500 510
pF1KE2 SECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDL
530 540 550 560 570 580
520 530 540 550 560 570
pF1KE2 SEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL
590 600 610 620 630 640
580 590 600 610 620 630
pF1KE2 GRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSE
650 660 670 680 690 700
640 650 660 670 680 690
pF1KE2 VTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARS
710 720 730 740 750 760
700 710 720 730 740 750
pF1KE2 KLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRLN
770 780 790 800 810 820
760 770 780 790 800 810
pF1KE2 LFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQD
830 840 850 860 870 880
820 830 840
pF1KE2 ISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
::::::::::::::::::::::::::::::::::::::
NP_001 ISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
890 900 910 920
>>XP_011530520 (OMIM: 602345,616410) PREDICTED: short tr (920 aa)
initn: 5111 init1: 5111 opt: 5537 Z-score: 5418.4 bits: 1013.7 E(85289): 0
Smith-Waterman score: 5537; 99.9% identity (99.9% similar) in 848 aa overlap (1-848:74-920)
10 20 30
pF1KE2 MEGSPSLRRMTVMREKGRRQAVRGPAFMFN
::::::::::::::::::::::::::::::
XP_011 NGGLEPRSAPSQREPHGYCPPPFSHGPDLSMEGSPSLRRMTVMREKGRRQAVRGPAFMFN
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE2 DRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVT
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE2 ELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAY
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE2 DEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSH
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE2 SRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFV
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE2 VGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQL
350 360 370 380 390 400
340 350 360 370 380 390
pF1KE2 LTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHA
410 420 430 440 450 460
400 410 420 430 440 450
pF1KE2 ASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMW
470 480 490 500 510 520
460 470 480 490 500 510
pF1KE2 SECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDL
530 540 550 560 570 580
520 530 540 550 560 570
pF1KE2 SEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL
590 600 610 620 630 640
580 590 600 610 620 630
pF1KE2 GRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSE
650 660 670 680 690 700
640 650 660 670 680 690
pF1KE2 VTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARS
710 720 730 740 750 760
700 710 720 730 740 750
pF1KE2 KLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRLN
770 780 790 800 810 820
760 770 780 790 800 810
pF1KE2 LFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQD
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_011 LFTQSNSRVFESHSFNSILNQPTRYQ-IMKRLIKRYVLKAQVDKENDEVNEGELKEIKQD
830 840 850 860 870 880
820 830 840
pF1KE2 ISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
::::::::::::::::::::::::::::::::::::::
XP_011 ISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
890 900 910 920
>>XP_016864067 (OMIM: 602345,616410) PREDICTED: short tr (936 aa)
initn: 5394 init1: 4931 opt: 4936 Z-score: 4830.7 bits: 905.0 E(85289): 0
Smith-Waterman score: 5495; 98.0% identity (98.0% similar) in 864 aa overlap (1-848:74-936)
10 20 30
pF1KE2 MEGSPSLRRMTVMREKGRRQAVRGPAFMFN
::::::::::::::::::::::::::::::
XP_016 NGGLEPRSAPSQREPHGYCPPPFSHGPDLSMEGSPSLRRMTVMREKGRRQAVRGPAFMFN
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE2 DRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVT
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE2 ELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAY
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE2 DEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSH
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE2 SRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFV
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE2 VGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQL
350 360 370 380 390 400
340 350 360 370 380 390
pF1KE2 LTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHA
410 420 430 440 450 460
400 410 420 430 440 450
pF1KE2 ASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMW
470 480 490 500 510 520
460 470 480 490 500 510
pF1KE2 SECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDL
530 540 550 560 570 580
520 530 540 550 560 570
pF1KE2 SEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL
590 600 610 620 630 640
580 590 600 610 620 630
pF1KE2 GRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSE
650 660 670 680 690 700
640 650 660 670 680 690
pF1KE2 VTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARS
710 720 730 740 750 760
700 710 720 730 740
pF1KE2 KLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSR--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRFT
770 780 790 800 810 820
750 760 770 780 790
pF1KE2 --------------LNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDK
:::::::::::::::::::::::::::: :::::::::::::::::
XP_016 KCFPVHLNLMQRCELNLFTQSNSRVFESHSFNSILNQPTRYQ-IMKRLIKRYVLKAQVDK
830 840 850 860 870 880
800 810 820 830 840
pF1KE2 ENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
890 900 910 920 930
>>XP_011530519 (OMIM: 602345,616410) PREDICTED: short tr (937 aa)
initn: 4931 init1: 4931 opt: 4931 Z-score: 4825.8 bits: 904.1 E(85289): 0
Smith-Waterman score: 5514; 98.1% identity (98.1% similar) in 864 aa overlap (1-848:74-937)
10 20 30
pF1KE2 MEGSPSLRRMTVMREKGRRQAVRGPAFMFN
::::::::::::::::::::::::::::::
XP_011 NGGLEPRSAPSQREPHGYCPPPFSHGPDLSMEGSPSLRRMTVMREKGRRQAVRGPAFMFN
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE2 DRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVT
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE2 ELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAY
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE2 DEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSH
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE2 SRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFV
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE2 VGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQL
350 360 370 380 390 400
340 350 360 370 380 390
pF1KE2 LTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHA
410 420 430 440 450 460
400 410 420 430 440 450
pF1KE2 ASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMW
470 480 490 500 510 520
460 470 480 490 500 510
pF1KE2 SECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDL
530 540 550 560 570 580
520 530 540 550 560 570
pF1KE2 SEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL
590 600 610 620 630 640
580 590 600 610 620 630
pF1KE2 GRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSE
650 660 670 680 690 700
640 650 660 670 680 690
pF1KE2 VTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARS
710 720 730 740 750 760
700 710 720 730 740
pF1KE2 KLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSR--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRFT
770 780 790 800 810 820
750 760 770 780 790
pF1KE2 --------------LNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDK
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCFPVHLNLMQRCELNLFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDK
830 840 850 860 870 880
800 810 820 830 840
pF1KE2 ENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
890 900 910 920 930
>>XP_016864068 (OMIM: 602345,616410) PREDICTED: short tr (893 aa)
initn: 4930 init1: 4930 opt: 4930 Z-score: 4825.1 bits: 903.9 E(85289): 0
Smith-Waterman score: 5309; 96.7% identity (96.7% similar) in 848 aa overlap (1-848:74-893)
10 20 30
pF1KE2 MEGSPSLRRMTVMREKGRRQAVRGPAFMFN
::::::::::::::::::::::::::::::
XP_016 NGGLEPRSAPSQREPHGYCPPPFSHGPDLSMEGSPSLRRMTVMREKGRRQAVRGPAFMFN
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE2 DRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVT
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE2 ELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLLKKENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAY
170 180 190 200 210 220
160 170 180 190 200 210
pF1KE2 DEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSH
230 240 250 260 270 280
220 230 240 250 260 270
pF1KE2 SRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRSRINAYKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFV
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE2 VGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGVLDLCRDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQL
350 360 370 380 390 400
340 350 360 370 380 390
pF1KE2 LTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTIWYENLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHA
410 420 430 440 450 460
400 410 420 430 440 450
pF1KE2 ASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASFIIFLGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMW
470 480 490 500 510 520
460 470 480 490 500 510
pF1KE2 SECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SECKELWLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDL
530 540 550 560 570 580
520 530 540 550 560 570
pF1KE2 SEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVTLPPEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISL
590 600 610 620 630 640
580 590 600 610 620 630
pF1KE2 GRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRTVKDIFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSE
650 660 670 680 690 700
640 650 660 670 680 690
pF1KE2 VTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTSVVLKYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARS
710 720 730 740 750 760
700 710 720 730 740 750
pF1KE2 KLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLWLSYFDDGKTLPPPFSLVPSPKSFVYFIMRIVNFPKCRRRRLQKDIEMGMGNSKSR--
770 780 790 800 810 820
760 770 780 790 800 810
pF1KE2 LFTQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQD
::::::::::::::::::::::::::::::::::
XP_016 --------------------------QIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQD
830 840 850
820 830 840
pF1KE2 ISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
::::::::::::::::::::::::::::::::::::::
XP_016 ISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
860 870 880 890
>>XP_011541270 (OMIM: 603652,603965) PREDICTED: short tr (876 aa)
initn: 4189 init1: 2192 opt: 3832 Z-score: 3751.8 bits: 705.3 E(85289): 3.1e-202
Smith-Waterman score: 4158; 73.3% identity (88.7% similar) in 858 aa overlap (8-841:12-866)
10 20 30 40 50
pF1KE2 MEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVR
::.::.:::::: : ::::.::.::.:::. ::::::::::::::::::
XP_011 MSRGSDNRLAHRRQTVLREKGRRLANRGPAYMFSDRSTSLSIEEERFLDAAEYGNIPVVR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 KMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVR
::::: ..::::::::::::::::::.:::::.::::::::::.:.::::::::::::::
XP_011 KMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDALLLAISKGYVR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 IVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVV
::::::.::.:: .:::. :: ..:::.:::::::::::::: :.::::::::::.::.:
XP_011 IVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 HMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVL
: :: :::::::::::::::.:: .::.:::::::::::::::::::::::::::::::.
XP_011 HTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVM
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 TALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEP
:::::::::: ::::::::::::.::::::::::::.:::::..::::::::::.:.
XP_011 TALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVGLLDLCRNTEEVEAILNGDVET---
250 260 270 280 290
300 310 320 330 340 350
pF1KE2 LEVHRH-KASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLV
:. : . .:::.::::::::::::::::::::::.::::::::::.::.:.: ::::.
XP_011 LQSGDHGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLSIWYENLSGLRQQTMAVKFLVVLA
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 VALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLP
::.::::::. ::.::::..:::.:.:::::::::::: :::::::.::.::::: ::
XP_011 VAIGLPFLALIYWFAPCSKMGKIMRGPFMKFVAHAASFTIFLGLLVMNAADRFEGTKLLP
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE2 NITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFG
: : :: ::.::.::. :.: ::::. ::.::.:.::::.: .::.::...:::.::::
XP_011 NETSTDNAKQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFG
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE2 MLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQ
::.:: :.: :::.:: .:.:::. .:. .::..::: ...:.. :: :: :::::
XP_011 MLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQ
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE2 IISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGM
:::::::::::::::::::::::::::::::::::::::::::::::.::::: ::::::
XP_011 IISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGM
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE2 FILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYN
: :::::.::: : ::::::::::::::.::::::: :::..:.:::::::::::::.::
XP_011 FNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYN
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE2 VTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKS
::::.:::::::::::::.::::::.::::::::.:::.:::..:.::: ::.:::::::
XP_011 VTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKS
660 670 680 690 700 710
720 730 740 750
pF1KE2 FVYFIMR----IVNFPKCRRRRLQKDIEMGMGNSKSRLNLF-------------------
. :.... : .. . ... .:.: ::. : ...:...
XP_011 LFYLLLKLKKWISELFQGHKKGFQEDAEMNKINEEKKLGILGSHEDLSKLSLDKKQVGHN
720 730 740 750 760 770
760 770 780 790 800 810
pF1KE2 TQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDIS
: . : :. .::. : : .::.:::::::::::.::.:::.::::::::::::::::
XP_011 KQPSIRSSEDFHLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDIS
780 790 800 810 820 830
820 830 840
pF1KE2 SLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
::::::::.::: ::.:: ::..:.:::.
XP_011 SLRYELLEEKSQNTEDLAELIRELGEKLSMEPNQEETNR
840 850 860 870
>>NP_004612 (OMIM: 603652,603965) short transient recept (931 aa)
initn: 4189 init1: 2192 opt: 3832 Z-score: 3751.4 bits: 705.3 E(85289): 3.2e-202
Smith-Waterman score: 4158; 73.3% identity (88.7% similar) in 858 aa overlap (8-841:67-921)
10 20 30
pF1KE2 MEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLT
::.::.:::::: : ::::.::.::.:::.
NP_004 ELGEDGCPQAPLPCYGYYPCFRGSDNRLAHRRQTVLREKGRRLANRGPAYMFSDRSTSLS
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE2 AEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKE
::::::::::::::::::::::: ..::::::::::::::::::.:::::.::::::::
NP_004 IEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKE
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE2 NLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRF
::.:.::::::::::::::::::::.::.:: .:::. :: ..:::.:::::::::::::
NP_004 NLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRF
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE2 SPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINA
: :.::::::::::.::.:: :: :::::::::::::::.:: .::.:::::::::::::
NP_004 SHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSRSRINA
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE2 YKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLC
::::::::::::::::::.:::::::::: ::::::::::::.::::::::::::.::::
NP_004 YKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFKNDYKKLSMQCKDFVVGLLDLC
280 290 300 310 320 330
280 290 300 310 320 330
pF1KE2 RDSEEVEAILNGDLESAEPLEVHRH-KASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYE
:..::::::::::.:. :. : . .:::.::::::::::::::::::::::.::::
NP_004 RNTEEVEAILNGDVET---LQSGDHGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLSIWYE
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE2 NLSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIF
::::::.::.:.: ::::.::.::::::. ::.::::..:::.:.:::::::::::: ::
NP_004 NLSGLRQQTMAVKFLVVLAVAIGLPFLALIYWFAPCSKMGKIMRGPFMKFVAHAASFTIF
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE2 LGLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKEL
:::::.::.::::: ::: : :: ::.::.::. :.: ::::. ::.::.:.::::.
NP_004 LGLLVMNAADRFEGTKLLPNETSTDNAKQLFRMKTSCFSWMEMLIISWVIGMIWAECKEI
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE2 WLEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLP
: .::.::...:::.::::::.:: :.: :::.:: .:.:::. .:. .::..:::
NP_004 WTQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLG
520 530 540 550 560 570
520 530 540 550 560 570
pF1KE2 PEIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKD
...:.. :: :: ::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DNVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKD
580 590 600 610 620 630
580 590 600 610 620 630
pF1KE2 IFKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVL
::::::.::::: ::::::: :::::.::: : ::::::::::::::.::::::: :::.
NP_004 IFKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVI
640 650 660 670 680 690
640 650 660 670 680 690
pF1KE2 KYDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSY
.:.:::::::::::::.::::::.:::::::::::::.::::::.::::::::.:::.::
NP_004 NYNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSY
700 710 720 730 740 750
700 710 720 730 740 750
pF1KE2 FDDGKTLPPPFSLVPSPKSFVYFIMR----IVNFPKCRRRRLQKDIEMGMGNSKSRLNLF
:..:.::: ::.:::::::. :.... : .. . ... .:.: ::. : ...:...
NP_004 FEEGRTLPVPFNLVPSPKSLFYLLLKLKKWISELFQGHKKGFQEDAEMNKINEEKKLGIL
760 770 780 790 800 810
760 770 780 790
pF1KE2 -------------------TQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVD
: . : :. .::. : : .::.:::::::::::.::.:
NP_004 GSHEDLSKLSLDKKQVGHNKQPSIRSSEDFHLNSFNNPPRQYQKIMKRLIKRYVLQAQID
820 830 840 850 860 870
800 810 820 830 840
pF1KE2 KENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
::.::::::::::::::::::::::::.::: ::.:: ::..:.:::.
NP_004 KESDEVNEGELKEIKQDISSLRYELLEEKSQNTEDLAELIRELGEKLSMEPNQEETNR
880 890 900 910 920 930
>>XP_016873711 (OMIM: 603652,603965) PREDICTED: short tr (845 aa)
initn: 4087 init1: 2192 opt: 3730 Z-score: 3652.3 bits: 686.8 E(85289): 1.1e-196
Smith-Waterman score: 4056; 73.3% identity (88.7% similar) in 838 aa overlap (28-841:1-835)
10 20 30 40 50 60
pF1KE2 MEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLE
::.::.:::. ::::::::::::::::::::::
XP_016 MFSDRSTSLSIEEERFLDAAEYGNIPVVRKMLE
10 20 30
70 80 90 100 110 120
pF1KE2 ESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIGDALLLAISKGYVRIVEA
: ..::::::::::::::::::.:::::.::::::::::.:.::::::::::::::::::
XP_016 ECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVGDALLLAISKGYVRIVEA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 ILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLL
::.::.:: .:::. :: ..:::.:::::::::::::: :.::::::::::.::.:: ::
XP_016 ILSHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 MKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINAYKGLASPAYLSLSSEDPVLTALE
:::::::::::::::.:: .::.:::::::::::::::::::::::::::::::.::::
XP_016 RKGARIERPHDYFCKCNDCNQKQKHDSFSHSRSRINAYKGLASPAYLSLSSEDPVMTALE
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 LSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDSEEVEAILNGDLESAEPLEVH
:::::: ::::::::::::.::::::::::::.:::::..::::::::::.:. :.
XP_016 LSNELAVLANIEKEFKNDYKKLSMQCKDFVVGLLDLCRNTEEVEAILNGDVET---LQSG
220 230 240 250 260 270
310 320 330 340 350
pF1KE2 RH-KASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTIAIKCLVVLVVALG
: . .:::.::::::::::::::::::::::.::::::::::.::.:.: ::::.::.:
XP_016 DHGRPNLSRLKLAIKYEVKKFVAHPNCQQQLLSIWYENLSGLRQQTMAVKFLVVLAVAIG
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE2 LPFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFLGLLVFNASDRFEGITTLPNITV
:::::. ::.::::..:::.:.:::::::::::: :::::::.::.::::: ::: :
XP_016 LPFLALIYWFAPCSKMGKIMRGPFMKFVAHAASFTIFLGLLVMNAADRFEGTKLLPNETS
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE2 TDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELWLEGPREYILQLWNVLDFGMLSI
:: ::.::.::. :.: ::::. ::.::.:.::::.: .::.::...:::.::::::.:
XP_016 TDNAKQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIWTQGPKEYLFELWNMLDFGMLAI
400 410 420 430 440 450
480 490 500 510 520 530
pF1KE2 FIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPPEIQYFTYARDKWLPSDPQIISE
: :.: :::.:: .:.:::. .:. .::..::: ...:.. :: :: :::::::::
XP_016 FAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQIISE
460 470 480 490 500 510
540 550 560 570 580 590
pF1KE2 GLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFFAFMIGMFILY
:::::::::::::::::::::::::::::::::::::::::::.::::: ::::::: ::
XP_016 GLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVIFIMVFVAFMIGMFNLY
520 530 540 550 560 570
600 610 620 630 640 650
pF1KE2 SYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLKYDHKFIENIGYVLYGIYNVTMV
:::.::: : ::::::::::::::.::::::: :::..:.:::::::::::::.::::::
XP_016 SYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVINYNHKFIENIGYVLYGVYNVTMV
580 590 600 610 620 630
660 670 680 690 700 710
pF1KE2 VVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYFDDGKTLPPPFSLVPSPKSFVYF
.:::::::::::::.::::::.::::::::.:::.:::..:.::: ::.:::::::. :.
XP_016 IVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYFEEGRTLPVPFNLVPSPKSLFYL
640 650 660 670 680 690
720 730 740 750
pF1KE2 IMR----IVNFPKCRRRRLQKDIEMGMGNSKSRLNLF-------------------TQSN
... : .. . ... .:.: ::. : ...:... : .
XP_016 LLKLKKWISELFQGHKKGFQEDAEMNKINEEKKLGILGSHEDLSKLSLDKKQVGHNKQPS
700 710 720 730 740 750
760 770 780 790 800 810
pF1KE2 SRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRY
: :. .::. : : .::.:::::::::::.::.:::.::::::::::::::::::::
XP_016 IRSSEDFHLNSFNNPPRQYQKIMKRLIKRYVLQAQIDKESDEVNEGELKEIKQDISSLRY
760 770 780 790 800 810
820 830 840
pF1KE2 ELLEDKSQATEELAILIHKLSEKLNPSMLRCE
::::.::: ::.:: ::..:.:::.
XP_016 ELLEEKSQNTEDLAELIRELGEKLSMEPNQEETNR
820 830 840
>>XP_016873710 (OMIM: 603652,603965) PREDICTED: short tr (815 aa)
initn: 3544 init1: 1799 opt: 1822 Z-score: 1787.1 bits: 341.7 E(85289): 8.4e-93
Smith-Waterman score: 3307; 62.9% identity (76.1% similar) in 857 aa overlap (8-841:67-805)
10 20 30
pF1KE2 MEGSPSLRRMTVMREKGRRQAVRGPAFMFNDRGTSLT
::.::.:::::: : ::::.::.::.:::.
XP_016 ELGEDGCPQAPLPCYGYYPCFRGSDNRLAHRRQTVLREKGRRLANRGPAYMFSDRSTSLS
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE2 AEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKE
::::::::::::::::::::::: ..::::::::::::::::::.:::::.::::::::
XP_016 IEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKE
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE2 NLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRF
::.:.::::::::::::::::::::.::.:: .:::. :: ..:::.:::::::::::::
XP_016 NLSRVGDALLLAISKGYVRIVEAILSHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRF
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE2 SPDITPIILAAHCQKYEVVHMLLMKGARIERPHDYFCKCGDCMEKQRHDSFSHSRSRINA
: :.::::::::::.::.:: :: :::::::::::::::.:: .::.:::::::::::::
XP_016 SHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDYFCKCNDCNQKQKHDSFSHSRSRINA
220 230 240 250 260 270
220 230 240 250 260 270
pF1KE2 YKGLASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLC
::::::::::::::::::.:::::::::: :::::::::
XP_016 YKGLASPAYLSLSSEDPVMTALELSNELAVLANIEKEFK---------------------
280 290 300 310
280 290 300 310 320 330
pF1KE2 RDSEEVEAILNGDLESAEPLEVHRHKASLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYEN
XP_016 ------------------------------------------------------------
340 350 360 370 380 390
pF1KE2 LSGLREQTIAIKCLVVLVVALGLPFLAIGYWIAPCSRLGKILRSPFMKFVAHAASFIIFL
.:::.:.:::::::::::: :::
XP_016 -------------------------------------MGKIMRGPFMKFVAHAASFTIFL
320 330
400 410 420 430 440 450
pF1KE2 GLLVFNASDRFEGITTLPNITVTDYPKQIFRVKTTQFTWTEMLIMVWVLGMMWSECKELW
::::.::.::::: ::: : :: ::.::.::. :.: ::::. ::.::.:.::::.:
XP_016 GLLVMNAADRFEGTKLLPNETSTDNAKQLFRMKTSCFSWMEMLIISWVIGMIWAECKEIW
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE2 LEGPREYILQLWNVLDFGMLSIFIAAFTARFLAFLQATKAQQYVDSYVQESDLSEVTLPP
.::.::...:::.::::::.:: :.: :::.:: .:.:::. .:. .::..:::
XP_016 TQGPKEYLFELWNMLDFGMLAIFAASFIARFMAFWHASKAQSIIDANDTLKDLTKVTLGD
400 410 420 430 440 450
520 530 540 550 560 570
pF1KE2 EIQYFTYARDKWLPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDI
...:.. :: :: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVKYYNLARIKWDPSDPQIISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDI
460 470 480 490 500 510
580 590 600 610 620 630
pF1KE2 FKFMVLFIMVFFAFMIGMFILYSYYLGAKVNAAFTTVEESFKTLFWSIFGLSEVTSVVLK
:::::.::::: ::::::: :::::.::: : ::::::::::::::.::::::: :::..
XP_016 FKFMVIFIMVFVAFMIGMFNLYSYYIGAKQNEAFTTVEESFKTLFWAIFGLSEVKSVVIN
520 530 540 550 560 570
640 650 660 670 680 690
pF1KE2 YDHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARSKLWLSYF
:.:::::::::::::.::::::.:::::::::::::.::::::.::::::::.:::.:::
XP_016 YNHKFIENIGYVLYGVYNVTMVIVLLNMLIAMINSSFQEIEDDADVEWKFARAKLWFSYF
580 590 600 610 620 630
700 710 720 730 740 750
pF1KE2 DDGKTLPPPFSLVPSPKSFVYFIMR----IVNFPKCRRRRLQKDIEMGMGNSKSRLNLF-
..:.::: ::.:::::::. :.... : .. . ... .:.: ::. : ...:...
XP_016 EEGRTLPVPFNLVPSPKSLFYLLLKLKKWISELFQGHKKGFQEDAEMNKINEEKKLGILG
640 650 660 670 680 690
760 770 780 790
pF1KE2 ------------------TQSNSRVFESHSFNSILNQPTRYQQIMKRLIKRYVLKAQVDK
: . : :. .::. : : .::.:::::::::::.::.::
XP_016 SHEDLSKLSLDKKQVGHNKQPSIRSSEDFHLNSFNNPPRQYQKIMKRLIKRYVLQAQIDK
700 710 720 730 740 750
800 810 820 830 840
pF1KE2 ENDEVNEGELKEIKQDISSLRYELLEDKSQATEELAILIHKLSEKLNPSMLRCE
:.::::::::::::::::::::::::.::: ::.:: ::..:.:::.
XP_016 ESDEVNEGELKEIKQDISSLRYELLEEKSQNTEDLAELIRELGEKLSMEPNQEETNR
760 770 780 790 800 810
848 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:30:14 2016 done: Tue Nov 8 17:30:16 2016
Total Scan time: 8.910 Total Display time: 0.230
Function used was FASTA [36.3.4 Apr, 2011]