Result of FASTA (ccds) for
pFN21AE3424
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3424, 504 aa
1>>>pF1KE3424 504 - 504 aa - 504 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3561+/-0.00097; mu= 2.8516+/- 0.059
mean_var=322.3813+/-67.355, 0's: 0 Z-trim(115.5): 26 B-trim: 91 in 1/50
Lambda= 0.071431
statistics sampled from 16065 (16084) to 16065 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.494), width: 16
Scan time: 4.040
The best scores are: opt bits E(32554)
CCDS42440.1 ONECUT2 gene_id:9480|Hs108|chr18 ( 504) 3466 370.7 2.1e-102
CCDS10150.1 ONECUT1 gene_id:3175|Hs108|chr15 ( 465) 1849 204.0 2.9e-52
CCDS45900.1 ONECUT3 gene_id:390874|Hs108|chr19 ( 494) 1038 120.5 4.4e-27
>>CCDS42440.1 ONECUT2 gene_id:9480|Hs108|chr18 (504 aa)
initn: 3466 init1: 3466 opt: 3466 Z-score: 1951.9 bits: 370.7 E(32554): 2.1e-102
Smith-Waterman score: 3466; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)
10 20 30 40 50 60
pF1KE3 MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDYR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 PELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 HHHHQRLSGNVSGSFTLMRDERGLPAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 HHHHQRLSGNVSGSFTLMRDERGLPAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 NAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 NAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPGH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 TQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 DRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 DRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRR
430 440 450 460 470 480
490 500
pF1KE3 SLEKWQDDLSTGGSSSTSSTCTKA
::::::::::::::::::::::::
CCDS42 SLEKWQDDLSTGGSSSTSSTCTKA
490 500
>>CCDS10150.1 ONECUT1 gene_id:3175|Hs108|chr15 (465 aa)
initn: 1348 init1: 1017 opt: 1849 Z-score: 1051.7 bits: 204.0 E(32554): 2.9e-52
Smith-Waterman score: 1890; 63.4% identity (76.3% similar) in 514 aa overlap (20-504:1-465)
10 20 30 40 50 60
pF1KE3 MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQE
:: .::::..: ::: . . . ::
CCDS10 MNAQLTMEAIGELHGVSHEPVPAPADLLGG-----------
10 20 30
70 80 90 100 110
pF1KE3 LLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGG---
::: .:.... :: ::. . .: :::.::::
CCDS10 -----SPH--ARSSVAH-RGSHLPPAHPRSMG-----------------MASLLDGGSGG
40 50 60
120 130 140 150 160
pF1KE3 -DYR-----PELSI--PLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHH
::. :: :. ::: .:.:.:.. ::::.: .:::::::::::::::::::::
CCDS10 GDYHHHHRAPEHSLAGPLHPTMTMACET-PPGMSMPTTYTTLTPLQPLPPISTVSDKF--
70 80 90 100 110 120
170 180 190 200 210 220
pF1KE3 PHPHHHPHHHHH-HHHQRLSGNVSGSFTLMRDERGLPAMNNLYSPY-KEMPGMSQSLSPL
:: ::: ::::: ::::::.:::::::::::::::: .:::::.:: :.. ::.::::::
CCDS10 PHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLSPL
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE3 AATPLGNGLGGLHNAQQSLPNYGPPGH----DKMLSPN-FDAHHTAMLTR-GEQHLSRGL
... :::..::.::.::.:. :: ::::.:: :.::: ::: : :::::
CCDS10 SSS----GLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHL----
190 200 210 220 230
290 300 310 320 330
pF1KE3 GTPPAAMMSHLNGL--HHP-GH--TQSHGPVLAPSRERPPSSSSGSQVAT---SGQLEEI
:: .: : .::: ::: .: .:.:: .:. .:: : : .:.::.. :::.:::
CCDS10 -TPTSAGMVPINGLPPHHPHAHLNAQGHGQLLGTARE-PNPSVTGAQVSNGSNSGQMEEI
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE3 NTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWK
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 NTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWK
300 310 320 330 340 350
400 410 420 430 440 450
pF1KE3 WLQEPEFQRMSALRLAACKRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSK
:::::::::::::::::::::::: .:::.:. :: ::::::.::::: :::::::::::
CCDS10 WLQEPEFQRMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSK
360 370 380 390 400 410
460 470 480 490 500
pF1KE3 EMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLST--GGSSSTSSTCTKA
:.::::::::::::.::::::::::::::.::::. :. :.:::.:::::::
CCDS10 ELQITISQQLGLELSTVSNFFMNARRRSLDKWQDEGSSNSGNSSSSSSTCTKA
420 430 440 450 460
>>CCDS45900.1 ONECUT3 gene_id:390874|Hs108|chr19 (494 aa)
initn: 1167 init1: 949 opt: 1038 Z-score: 599.7 bits: 120.5 E(32554): 4.4e-27
Smith-Waterman score: 1452; 52.5% identity (69.5% similar) in 531 aa overlap (23-504:2-494)
10 20 30 40 50 60
pF1KE3 MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQE
::..:::: ::. : . .: :
CCDS45 MELSLESLGGLHSVAHAQAG------------------E
10 20
70 80 90 100 110
pF1KE3 LLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAA----AAAAAASRSAMVTSMASILDG
:: :: :: :.::.. :: : : :. ....... .. . . .: :
CCDS45 LL---SPGHA-RSAAAQHRGLVAPGRPGLVAGMASLLDGGGGGGGGGAGGAGGAGSAGGG
30 40 50 60 70
120 130 140 150 160 170
pF1KE3 GDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHP------
.:.: ::. ::: ::.:.:.. ::.: .::::::::: :::...:.::::.
CCDS45 ADFRGELAGPLHPAMGMACEA--PGLG--GTYTTLTPLQHLPPLAAVADKFHQHAAAAAV
80 90 100 110 120 130
180 190 200 210
pF1KE3 ------HPHHHPHHHHHHHH----QRLSGNVSGSFTLMRDERG-LPAMNNLYSPY-KEMP
::: ::: :::...::::::::::::. : ....::.:: ::.:
CCDS45 AGAHGGHPHAHPHPAAAPPPPPPPQRLAASVSGSFTLMRDERAALASVGHLYGPYGKELP
140 150 160 170 180 190
220 230 240 250 260
pF1KE3 GMSQSLSPLAATPLGNGLG-GLHNAQQSLP--------NYGPPGH---DKMLSPNFDAHH
.:. ::: .:: :.: .::.: : : :::::: ::.: : :
CCDS45 AMG---SPL--SPLPNALPPALHGAPQPPPPPPPPPLAAYGPPGHLAGDKLLPPAAFEPH
200 210 220 230 240
270 280 290 300 310
pF1KE3 TAMLTRGEQHLSRGL------------GTPPAA-MMSHLNGLHHPGHTQSHGPVLAPSRE
.:.: :.:. :.::: :. :: ... :.:: : .::: . .
CCDS45 AALLGRAEDALARGLPGGGGGTGSGGAGSGSAAGLLAPLGGLAAAG---AHGPHGGGG--
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE3 RPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLR
:..:.:. : .. :::::::::::::::::::::::::::::.:::::::::::::
CCDS45 -GPGGSGGGPSAGAAA-EEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLR
310 320 330 340 350 360
380 390 400 410 420 430
pF1KE3 NPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNKDRNNSQKKSRLVF
:::::::::::::::::::::::::::::::::::::::::::: .:.: . ::.::::
CCDS45 NPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEQQKERALQPKKQRLVF
370 380 390 400 410 420
440 450 460 470 480 490
pF1KE3 TDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLST--
::::::::.::::::::::::::.::::::::::.:::::::::::: ...: .. ::
CCDS45 TDLQRRTLIAIFKENKRPSKEMQVTISQQLGLELNTVSNFFMNARRRCMNRWAEEPSTAP
430 440 450 460 470 480
500
pF1KE3 GGSSSTSSTCTKA
:: .....: .::
CCDS45 GGPAGATATFSKA
490
504 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:32:37 2016 done: Tue Nov 8 04:32:38 2016
Total Scan time: 4.040 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]