Result of FASTA (omim) for
pFN21AE2422
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2422, 216 aa
1>>>pF1KE2422 216 - 216 aa - 216 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1765+/-0.000351; mu= 14.0296+/- 0.022
mean_var=60.0394+/-11.839, 0's: 0 Z-trim(112.5): 25 B-trim: 0 in 0/53
Lambda= 0.165522
statistics sampled from 21359 (21384) to 21359 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.251), width: 16
Scan time: 4.600
The best scores are: opt bits E(85289)
NP_775739 (OMIM: 609282) MOB kinase activator 1B i ( 216) 1465 358.2 6e-99
NP_001231695 (OMIM: 609282) MOB kinase activator 1 ( 221) 1432 350.3 1.4e-96
XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase ( 221) 1432 350.3 1.4e-96
XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase ( 240) 1432 350.3 1.5e-96
XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase ( 247) 1432 350.3 1.6e-96
NP_060691 (OMIM: 609281) MOB kinase activator 1A i ( 216) 1412 345.5 3.9e-95
NP_001304039 (OMIM: 609281) MOB kinase activator 1 ( 215) 1400 342.7 2.8e-94
NP_001304040 (OMIM: 609281) MOB kinase activator 1 ( 258) 1379 337.7 1.1e-92
NP_001231696 (OMIM: 609282) MOB kinase activator 1 ( 147) 947 234.4 7.4e-62
NP_001304041 (OMIM: 609281) MOB kinase activator 1 ( 138) 916 227.0 1.2e-59
XP_011531250 (OMIM: 609281) PREDICTED: MOB kinase ( 180) 883 219.2 3.5e-57
NP_443731 (OMIM: 611969) MOB kinase activator 2 is ( 237) 555 140.9 1.7e-33
NP_001165694 (OMIM: 611969) MOB kinase activator 2 ( 268) 551 140.0 3.6e-33
NP_001191023 (OMIM: 609361) MOB-like protein phoce ( 193) 193 54.4 1.5e-07
NP_955776 (OMIM: 609361) MOB-like protein phocein ( 193) 193 54.4 1.5e-07
NP_001094289 (OMIM: 609361) MOB-like protein phoce ( 204) 193 54.4 1.6e-07
NP_056202 (OMIM: 609361) MOB-like protein phocein ( 225) 193 54.4 1.7e-07
>>NP_775739 (OMIM: 609282) MOB kinase activator 1B isofo (216 aa)
initn: 1465 init1: 1465 opt: 1465 Z-score: 1897.5 bits: 358.2 E(85289): 6e-99
Smith-Waterman score: 1465; 100.0% identity (100.0% similar) in 216 aa overlap (1-216:1-216)
10 20 30 40 50 60
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
130 140 150 160 170 180
190 200 210
pF1KE2 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
::::::::::::::::::::::::::::::::::::
NP_775 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
190 200 210
>>NP_001231695 (OMIM: 609282) MOB kinase activator 1B is (221 aa)
initn: 1432 init1: 1432 opt: 1432 Z-score: 1854.7 bits: 350.3 E(85289): 1.4e-96
Smith-Waterman score: 1432; 100.0% identity (100.0% similar) in 211 aa overlap (6-216:11-221)
10 20 30 40 50
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE
130 140 150 160 170 180
180 190 200 210
pF1KE2 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
:::::::::::::::::::::::::::::::::::::::::
NP_001 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
190 200 210 220
>>XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase acti (221 aa)
initn: 1432 init1: 1432 opt: 1432 Z-score: 1854.7 bits: 350.3 E(85289): 1.4e-96
Smith-Waterman score: 1432; 100.0% identity (100.0% similar) in 211 aa overlap (6-216:11-221)
10 20 30 40 50
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE
130 140 150 160 170 180
180 190 200 210
pF1KE2 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
:::::::::::::::::::::::::::::::::::::::::
XP_005 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
190 200 210 220
>>XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase acti (240 aa)
initn: 1432 init1: 1432 opt: 1432 Z-score: 1854.2 bits: 350.3 E(85289): 1.5e-96
Smith-Waterman score: 1432; 100.0% identity (100.0% similar) in 211 aa overlap (6-216:30-240)
10 20 30
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATL
:::::::::::::::::::::::::::::::
XP_011 MTPNRVDRGAGQPRRTRWASSLAAEETRSGSRSSKTFKPKKNIPEGSHQYELLKHAEATL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE2 GSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 WADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLF
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE2 RVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
190 200 210 220 230 240
>>XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase acti (247 aa)
initn: 1432 init1: 1432 opt: 1432 Z-score: 1854.0 bits: 350.3 E(85289): 1.6e-96
Smith-Waterman score: 1432; 100.0% identity (100.0% similar) in 211 aa overlap (6-216:37-247)
10 20 30
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEAT
::::::::::::::::::::::::::::::
XP_016 TTANCSFDFPGSGDPFISNPLPATSSWYYSGSRSSKTFKPKKNIPEGSHQYELLKHAEAT
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE2 LGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEY
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 HWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE2 FRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKD
190 200 210 220 230 240
pF1KE2 R
:
XP_016 R
>>NP_060691 (OMIM: 609281) MOB kinase activator 1A isofo (216 aa)
initn: 1412 init1: 1412 opt: 1412 Z-score: 1829.1 bits: 345.5 E(85289): 3.9e-95
Smith-Waterman score: 1412; 95.8% identity (98.6% similar) in 216 aa overlap (1-216:1-216)
10 20 30 40 50 60
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
:::::.::::::::::::::::::::::::::::::::::::.:::::::::::::.:::
NP_060 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
::::::::::::::::.:::: :::::::::.::::::::::::::::::::::::::::
NP_060 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
:::::::::::::::::::::::::::::::::::::::::::::::: :.:::::::::
NP_060 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN
130 140 150 160 170 180
190 200 210
pF1KE2 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
::::::::::::::::::::::::::::::: ::::
NP_060 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
190 200 210
>>NP_001304039 (OMIM: 609281) MOB kinase activator 1A is (215 aa)
initn: 1379 init1: 1379 opt: 1400 Z-score: 1813.6 bits: 342.7 E(85289): 2.8e-94
Smith-Waterman score: 1400; 95.8% identity (98.1% similar) in 216 aa overlap (1-216:1-215)
10 20 30 40 50 60
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
::::: ::::::::::::::::::::::::::::::::::::.:::::::::::::.:::
NP_001 MSFLF-SRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
::::::::::::::::.:::: :::::::::.::::::::::::::::::::::::::::
NP_001 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
:::::::::::::::::::::::::::::::::::::::::::::::: :.:::::::::
NP_001 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN
120 130 140 150 160 170
190 200 210
pF1KE2 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
::::::::::::::::::::::::::::::: ::::
NP_001 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
180 190 200 210
>>NP_001304040 (OMIM: 609281) MOB kinase activator 1A is (258 aa)
initn: 1379 init1: 1379 opt: 1379 Z-score: 1785.3 bits: 337.7 E(85289): 1.1e-92
Smith-Waterman score: 1379; 96.2% identity (98.6% similar) in 210 aa overlap (7-216:49-258)
10 20 30
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATL
::::::::::::::::::::::::::::::
NP_001 CWPWSRIVLSSSDSAHLLALILTNFSCPRSSRSSKTFKPKKNIPEGSHQYELLKHAEATL
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 GSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYH
::::::.:::::::::::::.:::::::::::::::::::.:::: :::::::::.::::
NP_001 GSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYH
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 WADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLF
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE2 RVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
:::::::::::: :.:::::::::::::::::::::::::::::::::::::::: ::::
NP_001 RVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
200 210 220 230 240 250
>>NP_001231696 (OMIM: 609282) MOB kinase activator 1B is (147 aa)
initn: 969 init1: 947 opt: 947 Z-score: 1231.5 bits: 234.4 E(85289): 7.4e-62
Smith-Waterman score: 947; 99.3% identity (100.0% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
:::::::::::::::::.
NP_001 WVQDQLDDETLFPSKIGIINFCKGDPS
130 140
>>NP_001304041 (OMIM: 609281) MOB kinase activator 1A is (138 aa)
initn: 916 init1: 916 opt: 916 Z-score: 1191.9 bits: 227.0 E(85289): 1.2e-59
Smith-Waterman score: 916; 95.7% identity (99.3% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
:::::.::::::::::::::::::::::::::::::::::::.:::::::::::::.:::
NP_001 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
::::::::::::::::.:::: :::::::::.::::::::::::::::::::::::::::
NP_001 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
::::::::::::::::::
NP_001 WVQDQLDDETLFPSKIGV
130
216 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:39:27 2016 done: Mon Nov 7 19:39:28 2016
Total Scan time: 4.600 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]