Result of FASTA (omim) for
pFN21AE2070
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2070, 728 aa
1>>>pF1KE2070 728 - 728 aa - 728 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8911+/-0.000501; mu= 17.5517+/- 0.031
mean_var=159.0547+/-32.410, 0's: 0 Z-trim(113.6): 459 B-trim: 73 in 1/51
Lambda= 0.101695
statistics sampled from 22397 (22988) to 22397 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.629), E-opt: 0.2 (0.27), width: 16
Scan time: 11.210
The best scores are: opt bits E(85289)
NP_624302 (OMIM: 257920,600521) mannan-binding lec ( 728) 5077 758.3 2.4e-218
XP_011511291 (OMIM: 257920,600521) PREDICTED: mann ( 735) 5070 757.3 4.8e-218
XP_016862358 (OMIM: 257920,600521) PREDICTED: mann ( 702) 4905 733.1 9.1e-211
XP_016862361 (OMIM: 257920,600521) PREDICTED: mann ( 615) 4305 645.0 2.7e-184
NP_001870 (OMIM: 257920,600521) mannan-binding lec ( 699) 3333 502.4 2.4e-141
XP_011511292 (OMIM: 257920,600521) PREDICTED: mann ( 706) 3326 501.4 5e-141
XP_016862360 (OMIM: 257920,600521) PREDICTED: mann ( 660) 3046 460.3 1.1e-128
XP_016862359 (OMIM: 257920,600521) PREDICTED: mann ( 668) 2784 421.9 4.2e-117
NP_001027019 (OMIM: 257920,600521) mannan-binding ( 380) 2565 389.4 1.4e-107
XP_011511293 (OMIM: 257920,600521) PREDICTED: mann ( 387) 2558 388.4 2.9e-107
XP_006713764 (OMIM: 257920,600521) PREDICTED: mann ( 354) 2393 364.1 5.3e-100
NP_006601 (OMIM: 605102,613791) mannan-binding lec ( 686) 1629 252.4 4.4e-66
NP_001724 (OMIM: 216950,613785) complement C1r sub ( 705) 1298 203.9 1.8e-51
XP_016875404 (OMIM: 216950,613785) PREDICTED: comp ( 719) 1298 203.9 1.9e-51
NP_001725 (OMIM: 120580,613783) complement C1s sub ( 688) 1280 201.2 1.1e-50
NP_958850 (OMIM: 120580,613783) complement C1s sub ( 688) 1280 201.2 1.1e-50
XP_005253817 (OMIM: 120580,613783) PREDICTED: comp ( 688) 1280 201.2 1.1e-50
XP_016855586 (OMIM: 605102,613791) PREDICTED: mann ( 332) 1110 175.9 2.4e-43
NP_631947 (OMIM: 605102,613791) mannan-binding lec ( 185) 686 113.3 8.8e-25
XP_011528291 (OMIM: 206200,609862) PREDICTED: tran ( 680) 496 86.2 4.8e-16
NP_068813 (OMIM: 606797) suppressor of tumorigenic ( 855) 457 80.6 2.9e-14
NP_036597 (OMIM: 606743) tolloid-like protein 2 pr (1015) 441 78.4 1.6e-13
NP_001298186 (OMIM: 176930,188050,601367,613679,61 ( 606) 431 76.6 3.3e-13
NP_000497 (OMIM: 176930,188050,601367,613679,61439 ( 622) 431 76.6 3.3e-13
NP_001275929 (OMIM: 206200,609862) transmembrane p ( 824) 402 72.5 7.6e-12
NP_002764 (OMIM: 600823) prostasin preproprotein [ ( 343) 392 70.5 1.2e-11
XP_011515117 (OMIM: 608399) PREDICTED: CUB and sus (2173) 364 67.5 6.4e-10
XP_016868501 (OMIM: 608399) PREDICTED: CUB and sus (3463) 364 67.8 8.5e-10
XP_016868500 (OMIM: 608399) PREDICTED: CUB and sus (3507) 364 67.8 8.6e-10
NP_443132 (OMIM: 608399) CUB and sushi domain-cont (3538) 364 67.8 8.6e-10
XP_016868499 (OMIM: 608399) PREDICTED: CUB and sus (3577) 364 67.8 8.7e-10
XP_011515118 (OMIM: 608399) PREDICTED: CUB and sus (3603) 364 67.8 8.7e-10
XP_016868498 (OMIM: 608399) PREDICTED: CUB and sus (3637) 364 67.8 8.8e-10
NP_937757 (OMIM: 608399) CUB and sushi domain-cont (3667) 364 67.8 8.8e-10
XP_016868497 (OMIM: 608399) PREDICTED: CUB and sus (3681) 364 67.8 8.8e-10
NP_937756 (OMIM: 608399) CUB and sushi domain-cont (3707) 364 67.8 8.9e-10
XP_011520753 (OMIM: 613797) PREDICTED: serine prot ( 280) 325 60.6 1e-08
XP_011520754 (OMIM: 613797) PREDICTED: serine prot ( 280) 325 60.6 1e-08
NP_690851 (OMIM: 613797) serine protease 33 precur ( 280) 325 60.6 1e-08
NP_001171704 (OMIM: 607021) seizure 6-like protein (1011) 332 62.4 1.1e-08
XP_005261496 (OMIM: 607021) PREDICTED: seizure 6-l (1012) 332 62.4 1.1e-08
NP_001171703 (OMIM: 607021) seizure 6-like protein (1013) 332 62.4 1.1e-08
XP_006724258 (OMIM: 607021) PREDICTED: seizure 6-l (1022) 332 62.4 1.1e-08
NP_001171702 (OMIM: 607021) seizure 6-like protein (1023) 332 62.4 1.1e-08
NP_066938 (OMIM: 607021) seizure 6-like protein is (1024) 332 62.4 1.1e-08
NP_001171706 (OMIM: 607021) seizure 6-like protein ( 948) 324 61.2 2.3e-08
XP_011528341 (OMIM: 607021) PREDICTED: seizure 6-l ( 957) 324 61.2 2.3e-08
XP_011528340 (OMIM: 607021) PREDICTED: seizure 6-l ( 958) 324 61.2 2.3e-08
XP_011528339 (OMIM: 607021) PREDICTED: seizure 6-l ( 959) 324 61.2 2.3e-08
XP_005262454 (OMIM: 122700,300746,300807,306900) P ( 418) 317 59.7 2.9e-08
>>NP_624302 (OMIM: 257920,600521) mannan-binding lectin (728 aa)
initn: 5077 init1: 5077 opt: 5077 Z-score: 4041.2 bits: 758.3 E(85289): 2.4e-218
Smith-Waterman score: 5077; 100.0% identity (100.0% similar) in 728 aa overlap (1-728:1-728)
10 20 30 40 50 60
pF1KE2 MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_624 MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_624 YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_624 DFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 CRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_624 CRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 PCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_624 PCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 CPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_624 CPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_624 TCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 MNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_624 MNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 FGSGALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_624 FGSGALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 LHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_624 LHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_624 TVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTC
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 LGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_624 LGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQS
670 680 690 700 710 720
pF1KE2 VVEPQVER
::::::::
NP_624 VVEPQVER
>>XP_011511291 (OMIM: 257920,600521) PREDICTED: mannan-b (735 aa)
initn: 5070 init1: 5070 opt: 5070 Z-score: 4035.6 bits: 757.3 E(85289): 4.8e-218
Smith-Waterman score: 5070; 100.0% identity (100.0% similar) in 727 aa overlap (2-728:9-735)
10 20 30 40 50
pF1KE2 MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVP
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPTFMSFRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 DGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 MSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 IEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 YRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 TWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 CSAQGVWMNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSAQGVWMNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTS
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE2 RVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVN
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE2 SSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGW
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE2 GISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYY
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE2 EGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWE
670 680 690 700 710 720
720
pF1KE2 QMGLPQSVVEPQVER
:::::::::::::::
XP_011 QMGLPQSVVEPQVER
730
>>XP_016862358 (OMIM: 257920,600521) PREDICTED: mannan-b (702 aa)
initn: 4905 init1: 4905 opt: 4905 Z-score: 3904.9 bits: 733.1 E(85289): 9.1e-211
Smith-Waterman score: 4905; 100.0% identity (100.0% similar) in 702 aa overlap (27-728:1-702)
10 20 30 40 50 60
pF1KE2 MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL
::::::::::::::::::::::::::::::::::
XP_016 MFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL
10 20 30
70 80 90 100 110 120
pF1KE2 YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 DFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRT
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 CRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 PCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE2 CPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIP
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE2 TCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVW
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE2 MNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKW
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE2 FGSGALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGSGALLSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVV
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE2 LHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNV
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE2 TVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTC
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE2 LGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQS
640 650 660 670 680 690
pF1KE2 VVEPQVER
::::::::
XP_016 VVEPQVER
700
>>XP_016862361 (OMIM: 257920,600521) PREDICTED: mannan-b (615 aa)
initn: 4305 init1: 4305 opt: 4305 Z-score: 3429.8 bits: 645.0 E(85289): 2.7e-184
Smith-Waterman score: 4305; 100.0% identity (100.0% similar) in 615 aa overlap (114-728:1-615)
90 100 110 120 130 140
pF1KE2 DQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDEC
::::::::::::::::::::::::::::::
XP_016 MSITFRSDFSNEERFTGFDAHYMAVDVDEC
10 20 30
150 160 170 180 190 200
pF1KE2 KEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFP
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE2 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGPKVLGPFCGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGPKVLGPFCGEK
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE2 APEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQPPVHGKIEPSQAKYFFKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQPPVHGKIEPSQAKYFFKD
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE2 QVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTR
220 230 240 250 260 270
390 400 410 420 430 440
pF1KE2 NNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPECGQPSRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPECGQPSRSL
280 290 300 310 320 330
450 460 470 480 490 500
pF1KE2 PSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQR
340 350 360 370 380 390
510 520 530 540 550 560
pF1KE2 RDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPV
400 410 420 430 440 450
570 580 590 600 610 620
pF1KE2 PLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLP
460 470 480 490 500 510
630 640 650 660 670 680
pF1KE2 VVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGL
520 530 540 550 560 570
690 700 710 720
pF1KE2 VSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVEPQVER
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVEPQVER
580 590 600 610
>>NP_001870 (OMIM: 257920,600521) mannan-binding lectin (699 aa)
initn: 3447 init1: 3081 opt: 3333 Z-score: 2658.5 bits: 502.4 E(85289): 2.4e-141
Smith-Waterman score: 3585; 73.3% identity (84.7% similar) in 726 aa overlap (1-717:1-697)
10 20 30 40 50 60
pF1KE2 MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 CRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 PCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 CPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVW
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 MNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKW
:::::::::::::: :: :. : .:. ::..:: :. : :: :.. :.. : .
NP_001 MNKVLGRSLPTCLPVCGLPKFSR-KLMARIFNGRPAQKGTTPWIAML-----SHL-NGQP
430 440 450 460 470
490 500 510 520 530
pF1KE2 FGSGALLSASWILTAAHVLRSQR-------RDTTVIPVSKEHVTVYLGLH-DVRDKSGAV
: .:.::..:::.:::: :... ::. .. : . :: : .:. .
NP_001 FCGGSLLGSSWIVTAAHCLHQSLDPEDPTLRDSDLL--SPSDFKIILGKHWRLRSDENEQ
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE2 NSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPH-MLGLVA
. .. ...:::... .....:.:::.: : :. :::.::: ::: . . .:.
NP_001 HLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAFVMPICLP----EGPQQEGAMVIVS
540 550 560 570 580
600 610 620 630 640 650
pF1KE2 GWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAG
::: .. . . ..:. ...:.: :. :. .: . . ::..:.:::
NP_001 GWG------------KQFLQRFPETLMEIEIPIVDHSTCQKAYAPLKKK--VTRDMICAG
590 600 610 620 630
660 670 680 690 700 710
pF1KE2 YYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWV
:::::.: ::::: .: .. .: . : :::: ..::.:. ::::. . . ::.
NP_001 EKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWG--DDCGKKDRYGVYSYIHHNKDWI
640 650 660 670 680 690
720
pF1KE2 WEQMGLPQSVVEPQVER
. :.
NP_001 QRVTGVRN
>>XP_011511292 (OMIM: 257920,600521) PREDICTED: mannan-b (706 aa)
initn: 3440 init1: 3074 opt: 3326 Z-score: 2652.9 bits: 501.4 E(85289): 5e-141
Smith-Waterman score: 3578; 73.2% identity (84.7% similar) in 725 aa overlap (2-717:9-704)
10 20 30 40 50
pF1KE2 MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVP
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPTFMSFRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 DGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 MSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 IEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 YRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 TWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 CSAQGVWMNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTS
::::::::::::::::::::: :: :. : .:. ::..:: :. : :: :.. :
XP_011 CSAQGVWMNKVLGRSLPTCLPVCGLPKFSR-KLMARIFNGRPAQKGTTPWIAML-----S
430 440 450 460 470
480 490 500 510 520
pF1KE2 RVPNDKWFGSGALLSASWILTAAHVLRSQR-------RDTTVIPVSKEHVTVYLGLH-DV
.. : . : .:.::..:::.:::: :... ::. .. : . :: : .
XP_011 HL-NGQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTLRDSDLL--SPSDFKIILGKHWRL
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE2 RDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPH
:. . . .. ...:::... .....:.:::.: : :. :::.::: ::: .
XP_011 RSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAFVMPICLP----EGPQQE
540 550 560 570 580
590 600 610 620 630 640
pF1KE2 -MLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVT
. .:.::: .. . . ..:. ...:.: :. :. .: . . ::
XP_011 GAMVIVSGWG------------KQFLQRFPETLMEIEIPIVDHSTCQKAYAPLKKK--VT
590 600 610 620 630
650 660 670 680 690 700
pF1KE2 ENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKV
..:.::: :::::.: ::::: .: .. .: . : :::: ..::.:. ::::. .
XP_011 RDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWG--DDCGKKDRYGVYSYI
640 650 660 670 680 690
710 720
pF1KE2 SNYVDWVWEQMGLPQSVVEPQVER
. ::. . :.
XP_011 HHNKDWIQRVTGVRN
700
>>XP_016862360 (OMIM: 257920,600521) PREDICTED: mannan-b (660 aa)
initn: 3421 init1: 3046 opt: 3046 Z-score: 2431.2 bits: 460.3 E(85289): 1.1e-128
Smith-Waterman score: 3376; 70.8% identity (80.1% similar) in 725 aa overlap (2-717:9-658)
10 20 30 40 50
pF1KE2 MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVP
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRPTFMSFRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 DGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 MSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 IEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 YRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 TWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE2 CSAQGVWMNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTS
:::::::::::::::::::::
XP_016 CSAQGVWMNKVLGRSLPTCLP---------------------------------------
430 440
480 490 500 510 520
pF1KE2 RVPNDKWFGSGALLSASWILTAAHVLRSQR-------RDTTVIPVSKEHVTVYLGLH-DV
:: :::.:::: :... ::. .. : . :: : .
XP_016 --------GS------SWIVTAAHCLHQSLDPEDPTLRDSDLL--SPSDFKIILGKHWRL
450 460 470 480
530 540 550 560 570 580
pF1KE2 RDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPH
:. . . .. ...:::... .....:.:::.: : :. :::.::: ::: .
XP_016 RSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAFVMPICLP----EGPQQE
490 500 510 520 530 540
590 600 610 620 630 640
pF1KE2 -MLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVT
. .:.::: .. . . ..:. ...:.: :. :. .: . . ::
XP_016 GAMVIVSGWG------------KQFLQRFPETLMEIEIPIVDHSTCQKAYAPLKKK--VT
550 560 570 580
650 660 670 680 690 700
pF1KE2 ENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKV
..:.::: :::::.: ::::: .: .. .: . : :::: ..::.:. ::::. .
XP_016 RDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWG--DDCGKKDRYGVYSYI
590 600 610 620 630 640
710 720
pF1KE2 SNYVDWVWEQMGLPQSVVEPQVER
. ::. . :.
XP_016 HHNKDWIQRVTGVRN
650 660
>>XP_016862359 (OMIM: 257920,600521) PREDICTED: mannan-b (668 aa)
initn: 2898 init1: 2532 opt: 2784 Z-score: 2223.4 bits: 421.9 E(85289): 4.2e-117
Smith-Waterman score: 3036; 69.9% identity (82.9% similar) in 648 aa overlap (79-717:48-666)
50 60 70 80 90 100
pF1KE2 NITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVL
.:::::::::::::::::::::::::::::
XP_016 SRTPHRARAHRQVKLGGPRPGSREHPRQENEVETEDQVLATFCGRETTDTEQTPGQEVVL
20 30 40 50 60 70
110 120 130 140 150 160
pF1KE2 SPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSC
80 90 100 110 120 130
170 180 190 200 210 220
pF1KE2 RFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQF
140 150 160 170 180 190
230 240 250 260 270 280
pF1KE2 EDIFDIEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDIFDIEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENR
200 210 220 230 240 250
290 300 310 320 330 340
pF1KE2 GWRLSYRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GWRLSYRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIE
260 270 280 290 300 310
350 360 370 380 390 400
pF1KE2 CLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNN
320 330 340 350 360 370
410 420 430 440 450 460
pF1KE2 TGIYTCSAQGVWMNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIV
:::::::::::::::::::::::::: :: :. : .:. ::..:: :. : :: :..
XP_016 TGIYTCSAQGVWMNKVLGRSLPTCLPVCGLPKFSR-KLMARIFNGRPAQKGTTPWIAML-
380 390 400 410 420 430
470 480 490 500 510 520
pF1KE2 VEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQR-------RDTTVIPVSKEHVTVYLG
:.. : . : .:.::..:::.:::: :... ::. .. : . ::
XP_016 ----SHL-NGQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTLRDSDLL--SPSDFKIILG
440 450 460 470 480
530 540 550 560 570 580
pF1KE2 LH-DVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPE
: .:. . . .. ...:::... .....:.:::.: : :. :::.::: :
XP_016 KHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAFVMPICLP----E
490 500 510 520 530 540
590 600 610 620 630
pF1KE2 GPAPH-MLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAECKTSYESRSG
:: . . .:.::: .. . . ..:. ...:.: :. :. .: .
XP_016 GPQQEGAMVIVSGWG------------KQFLQRFPETLMEIEIPIVDHSTCQKAYAPLKK
550 560 570 580 590
640 650 660 670 680 690
pF1KE2 NYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYG
. ::..:.::: :::::.: ::::: .: .. .: . : :::: ..::.:. ::
XP_016 K--VTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWG--DDCGKKDRYG
600 610 620 630 640
700 710 720
pF1KE2 VYTKVSNYVDWVWEQMGLPQSVVEPQVER
::. . . ::. . :.
XP_016 VYSYIHHNKDWIQRVTGVRN
650 660
>>NP_001027019 (OMIM: 257920,600521) mannan-binding lect (380 aa)
initn: 2561 init1: 2561 opt: 2565 Z-score: 2052.4 bits: 389.4 E(85289): 1.4e-107
Smith-Waterman score: 2565; 96.6% identity (97.6% similar) in 379 aa overlap (1-379:1-379)
10 20 30 40 50 60
pF1KE2 MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 CRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 PCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 CPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVW
::: . .::. .:
NP_001 TCKKNEIDLESELKSEQVTE
370 380
>>XP_011511293 (OMIM: 257920,600521) PREDICTED: mannan-b (387 aa)
initn: 2554 init1: 2554 opt: 2558 Z-score: 2046.7 bits: 388.4 E(85289): 2.9e-107
Smith-Waterman score: 2558; 96.6% identity (97.6% similar) in 378 aa overlap (2-379:9-386)
10 20 30 40 50
pF1KE2 MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVP
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRPTFMSFRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 DGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 MSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 LHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 IEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 YRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 TWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYT
:::::::::: . .::. .:
XP_011 TWSNKIPTCKKNEIDLESELKSEQVTE
370 380
728 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 11:58:45 2016 done: Sun Nov 6 11:58:47 2016
Total Scan time: 11.210 Total Display time: 0.170
Function used was FASTA [36.3.4 Apr, 2011]