Result of FASTA (ccds) for
pFN21AB7912
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7912, 331 aa
1>>>pF1KB7912 331 - 331 aa - 331 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.3300+/-0.00129; mu= 6.3271+/- 0.078
mean_var=380.4803+/-79.082, 0's: 0 Z-trim(112.4): 145 B-trim: 0 in 0/50
Lambda= 0.065752
statistics sampled from 13000 (13136) to 13000 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.404), width: 16
Scan time: 3.060
The best scores are: opt bits E(32554)
CCDS43164.1 SHOX2 gene_id:6474|Hs108|chr3 ( 331) 2199 222.3 4.3e-58
CCDS54664.1 SHOX2 gene_id:6474|Hs108|chr3 ( 319) 1614 166.8 2.1e-41
CCDS33884.2 SHOX2 gene_id:6474|Hs108|chr3 ( 355) 1479 154.0 1.6e-37
CCDS14106.1 SHOX gene_id:6473|Hs108|chrX ( 225) 730 82.7 3.1e-16
CCDS14106.1 SHOX gene_id:6473|Hs108|chrY ( 225) 730 82.7 3.1e-16
CCDS14107.1 SHOX gene_id:6473|Hs108|chrY ( 292) 722 82.1 6e-16
CCDS14107.1 SHOX gene_id:6473|Hs108|chrX ( 292) 722 82.1 6e-16
>>CCDS43164.1 SHOX2 gene_id:6474|Hs108|chr3 (331 aa)
initn: 2199 init1: 2199 opt: 2199 Z-score: 1156.4 bits: 222.3 E(32554): 4.3e-58
Smith-Waterman score: 2199; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331)
10 20 30 40 50 60
pF1KB7 MEELTAFVSKSFDQKVKEKKEAITYREVLESGPLRGAKEPTGCTEAGRDDRSSPAVRAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MEELTAFVSKSFDQKVKEKKEAITYREVLESGPLRGAKEPTGCTEAGRDDRSSPAVRAAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 GGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQDSHCNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 EARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQDSHCNV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TPLSFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPLATLAADSASAASVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 TPLSFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPLATLAADSASAASVV
250 260 270 280 290 300
310 320 330
pF1KB7 AAAAAAKTTSKNSSIADLRLKAKKHAAALGL
:::::::::::::::::::::::::::::::
CCDS43 AAAAAAKTTSKNSSIADLRLKAKKHAAALGL
310 320 330
>>CCDS54664.1 SHOX2 gene_id:6474|Hs108|chr3 (319 aa)
initn: 1573 init1: 1573 opt: 1614 Z-score: 856.7 bits: 166.8 E(32554): 2.1e-41
Smith-Waterman score: 2077; 96.4% identity (96.4% similar) in 331 aa overlap (1-331:1-319)
10 20 30 40 50 60
pF1KB7 MEELTAFVSKSFDQKVKEKKEAITYREVLESGPLRGAKEPTGCTEAGRDDRSSPAVRAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MEELTAFVSKSFDQKVKEKKEAITYREVLESGPLRGAKEPTGCTEAGRDDRSSPAVRAAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 GGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 KDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 EARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQDSHCNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQ------
190 200 210 220 230
250 260 270 280 290 300
pF1KB7 TPLSFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPLATLAADSASAASVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 ------VQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPLATLAADSASAASVV
240 250 260 270 280
310 320 330
pF1KB7 AAAAAAKTTSKNSSIADLRLKAKKHAAALGL
:::::::::::::::::::::::::::::::
CCDS54 AAAAAAKTTSKNSSIADLRLKAKKHAAALGL
290 300 310
>>CCDS33884.2 SHOX2 gene_id:6474|Hs108|chr3 (355 aa)
initn: 1426 init1: 1426 opt: 1479 Z-score: 787.0 bits: 154.0 E(32554): 1.6e-37
Smith-Waterman score: 2141; 93.2% identity (93.2% similar) in 355 aa overlap (1-331:1-355)
10 20 30 40 50 60
pF1KB7 MEELTAFVSKSFDQKVKEKKEAITYREVLESGPLRGAKEPTGCTEAGRDDRSSPAVRAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MEELTAFVSKSFDQKVKEKKEAITYREVLESGPLRGAKEPTGCTEAGRDDRSSPAVRAAG
10 20 30 40 50 60
70 80 90 100 110
pF1KB7 GGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTE-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 GGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEGRRKP
70 80 90 100 110 120
120 130 140 150
pF1KB7 -------------------VSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELE
:::::::::::::::::::::::::::::::::::::::::
CCDS33 TKAEVQATLLLPGEAFRFLVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB7 RLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEA
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB7 CRVAPYVNVGALRMPFQQDSHCNVTPLSFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 CRVAPYVNVGALRMPFQQDSHCNVTPLSFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMM
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB7 FPAPPFGLPLATLAADSASAASVVAAAAAAKTTSKNSSIADLRLKAKKHAAALGL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 FPAPPFGLPLATLAADSASAASVVAAAAAAKTTSKNSSIADLRLKAKKHAAALGL
310 320 330 340 350
>>CCDS14106.1 SHOX gene_id:6473|Hs108|chrX (225 aa)
initn: 880 init1: 676 opt: 730 Z-score: 404.9 bits: 82.7 E(32554): 3.1e-16
Smith-Waterman score: 800; 55.5% identity (69.1% similar) in 256 aa overlap (1-242:1-219)
10 20 30 40 50
pF1KB7 MEELTAFVSKSFDQKVKE----------KKEAITYREVLESGPLRGAKEPTGCTEAGRDD
::::::::::::::: :. ::..:::::::::: :. : : .:
CCDS14 MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARS-------RELGTSD
10 20 30 40 50
60 70 80 90 100
pF1KB7 RSSPAVRAAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVR----ELDMGAAERSR
: . :::. ::. ..: . :. .
CCDS14 SSLQDITE-----------------------------GGGHCPVHLFKDHVD-NDKEKLK
60 70 80
110 120 130 140 150 160
pF1KB7 EPGSPRLTEVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPD
: :. :..: : :...::.:. ...::::.::::::::::::::::::::::::::::
CCDS14 EFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPD
90 100 110 120 130 140
170 180 190 200 210 220
pF1KB7 AFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEACRVAPYVNVG
:::::::::::::::::::::::::::::::::::.::::..:.:....:::::::::.:
CCDS14 AFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMG
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB7 ALRMPFQQDSHCNVTPLSFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPL
:::::::: :. :
CCDS14 ALRMPFQQMEFCSCRPGWSIMA
210 220
>>CCDS14106.1 SHOX gene_id:6473|Hs108|chrY (225 aa)
initn: 880 init1: 676 opt: 730 Z-score: 404.9 bits: 82.7 E(32554): 3.1e-16
Smith-Waterman score: 800; 55.5% identity (69.1% similar) in 256 aa overlap (1-242:1-219)
10 20 30 40 50
pF1KB7 MEELTAFVSKSFDQKVKE----------KKEAITYREVLESGPLRGAKEPTGCTEAGRDD
::::::::::::::: :. ::..:::::::::: :. : : .:
CCDS14 MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARS-------RELGTSD
10 20 30 40 50
60 70 80 90 100
pF1KB7 RSSPAVRAAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVR----ELDMGAAERSR
: . :::. ::. ..: . :. .
CCDS14 SSLQDITE-----------------------------GGGHCPVHLFKDHVD-NDKEKLK
60 70 80
110 120 130 140 150 160
pF1KB7 EPGSPRLTEVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPD
: :. :..: : :...::.:. ...::::.::::::::::::::::::::::::::::
CCDS14 EFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPD
90 100 110 120 130 140
170 180 190 200 210 220
pF1KB7 AFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEACRVAPYVNVG
:::::::::::::::::::::::::::::::::::.::::..:.:....:::::::::.:
CCDS14 AFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMG
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB7 ALRMPFQQDSHCNVTPLSFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPL
:::::::: :. :
CCDS14 ALRMPFQQMEFCSCRPGWSIMA
210 220
>>CCDS14107.1 SHOX gene_id:6473|Hs108|chrY (292 aa)
initn: 1174 init1: 676 opt: 722 Z-score: 399.7 bits: 82.1 E(32554): 6e-16
Smith-Waterman score: 1164; 60.3% identity (73.0% similar) in 345 aa overlap (1-331:1-292)
10 20 30 40 50
pF1KB7 MEELTAFVSKSFDQKVKE----------KKEAITYREVLESGPLRGAKEPTGCTEAGRDD
::::::::::::::: :. ::..:::::::::: :. : : .:
CCDS14 MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARS-------RELGTSD
10 20 30 40 50
60 70 80 90 100
pF1KB7 RSSPAVRAAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVR----ELDMGAAERSR
: . :::. ::. ..: . :. .
CCDS14 SSLQDITE-----------------------------GGGHCPVHLFKDHVD-NDKEKLK
60 70 80
110 120 130 140 150 160
pF1KB7 EPGSPRLTEVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPD
: :. :..: : :...::.:. ...::::.::::::::::::::::::::::::::::
CCDS14 EFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPD
90 100 110 120 130 140
170 180 190 200 210 220
pF1KB7 AFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEACRVAPYVNVG
:::::::::::::::::::::::::::::::::::.::::..:.:....:::::::::.:
CCDS14 AFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMG
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB7 ALRMPFQQDSHCNVTPLSFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPL
:::::::: :::::::.. ::::: ::::::::::::.::: ::::::.
CCDS14 ALRMPFQQ------------VQAQLQLEG-VAHAHPHLHPHLAAHAPYLMFPPPPFGLPI
210 220 230 240 250
290 300 310 320 330
pF1KB7 ATLAADSASAASVVAAAAAAKTTSKNSSIADLRLKAKKHAAALGL
:.:: .:::::.:::::: :..:::::::::::::.::: ::::
CCDS14 ASLA-ESASAAAVVAAAA--KSNSKNSSIADLRLKARKHAEALGL
260 270 280 290
>>CCDS14107.1 SHOX gene_id:6473|Hs108|chrX (292 aa)
initn: 1174 init1: 676 opt: 722 Z-score: 399.7 bits: 82.1 E(32554): 6e-16
Smith-Waterman score: 1164; 60.3% identity (73.0% similar) in 345 aa overlap (1-331:1-292)
10 20 30 40 50
pF1KB7 MEELTAFVSKSFDQKVKE----------KKEAITYREVLESGPLRGAKEPTGCTEAGRDD
::::::::::::::: :. ::..:::::::::: :. : : .:
CCDS14 MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARS-------RELGTSD
10 20 30 40 50
60 70 80 90 100
pF1KB7 RSSPAVRAAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVR----ELDMGAAERSR
: . :::. ::. ..: . :. .
CCDS14 SSLQDITE-----------------------------GGGHCPVHLFKDHVD-NDKEKLK
60 70 80
110 120 130 140 150 160
pF1KB7 EPGSPRLTEVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPD
: :. :..: : :...::.:. ...::::.::::::::::::::::::::::::::::
CCDS14 EFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPD
90 100 110 120 130 140
170 180 190 200 210 220
pF1KB7 AFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEACRVAPYVNVG
:::::::::::::::::::::::::::::::::::.::::..:.:....:::::::::.:
CCDS14 AFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMG
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB7 ALRMPFQQDSHCNVTPLSFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPL
:::::::: :::::::.. ::::: ::::::::::::.::: ::::::.
CCDS14 ALRMPFQQ------------VQAQLQLEG-VAHAHPHLHPHLAAHAPYLMFPPPPFGLPI
210 220 230 240 250
290 300 310 320 330
pF1KB7 ATLAADSASAASVVAAAAAAKTTSKNSSIADLRLKAKKHAAALGL
:.:: .:::::.:::::: :..:::::::::::::.::: ::::
CCDS14 ASLA-ESASAAAVVAAAA--KSNSKNSSIADLRLKARKHAEALGL
260 270 280 290
331 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:53:16 2016 done: Sun Nov 6 05:53:16 2016
Total Scan time: 3.060 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]