FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3978, 392 aa
  1>>>pF1KE3978 392 - 392 aa - 392 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5163+/-0.000864; mu= 15.1514+/- 0.052
 mean_var=66.9585+/-13.298, 0's: 0 Z-trim(106.2): 151  B-trim: 4 in 1/49
 Lambda= 0.156737
 statistics sampled from 8702 (8864) to 8702 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.272), width:  16
 Scan time:  2.610

The best scores are:                                      opt bits E(32554)
CCDS33298.1 SPOPL gene_id:339745|Hs108|chr2        ( 392) 2641 606.3 1.6e-173
CCDS11551.1 SPOP gene_id:8405|Hs108|chr17          ( 374) 1932 445.9 2.8e-125
CCDS34609.1 KLHL7 gene_id:55975|Hs108|chr7         ( 586)  262 68.4 1.9e-11
CCDS47418.1 BTBD9 gene_id:114781|Hs108|chr6        ( 612)  259 67.7 3.2e-11


>>CCDS33298.1 SPOPL gene_id:339745|Hs108|chr2             (392 aa)
 initn: 2641 init1: 2641 opt: 2641  Z-score: 3228.9  bits: 606.3 E(32554): 1.6e-173
Smith-Waterman score: 2641; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392)

               10        20        30        40        50        60
pF1KE3 MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI
              310       320       330       340       350       360

              370       380       390  
pF1KE3 QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS
       ::::::::::::::::::::::::::::::::
CCDS33 QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS
              370       380       390  

>>CCDS11551.1 SPOP gene_id:8405|Hs108|chr17               (374 aa)
 initn: 2177 init1: 1932 opt: 1932  Z-score: 2362.7  bits: 445.9 E(32554): 2.8e-125
Smith-Waterman score: 2144; 80.6% identity (91.6% similar) in 392 aa overlap (1-392:1-374)

               10        20        30        40        50        60
pF1KE3 MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG
       ::: :.:: :..::.::.::::::::.::::::::::::::::::::::::.::::::::
CCDS11 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ
        .::.::::::::::::.:::::::::::::::::::::::::::.:::: :::::::::
CCDS11 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::... : .:
CCDS11 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR
       :::::::..::.::::.::::: . : ::::.:::..::::::::.::::::::::::::
CCDS11 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE
       :::::..:::::::: :::::.:::::::::.::::::::::::::::::.:::::::::
CCDS11 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI
       :.:. :.:::::::.:::.::.::::                   .:.:..::::::::.
CCDS11 NAAEILILADLHSADQLKTQAVDFINY------------------HASDVLETSGWKSMV
              310       320                         330       340  

              370       380       390  
pF1KE3 QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS
        :::::::::.:.::::::: .: ::::::::
CCDS11 VSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
            350       360       370    

>>CCDS34609.1 KLHL7 gene_id:55975|Hs108|chr7              (586 aa)
 initn: 244 init1: 244 opt: 262  Z-score: 318.8  bits: 68.4 E(32554): 1.9e-11
Smith-Waterman score: 262; 34.1% identity (68.1% similar) in 138 aa overlap (190-327:34-171)

     160       170       180       190       200       210         
pF1KE3 EVSVVQDSVNISGHTNTNTLKVPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLA
                                     ..:. ..  . :  ..:. ... ::. :::
CCDS34 SGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLA
            10        20        30        40        50        60   

     220       230       240       250       260       270         
pF1KE3 ARSPVFNAMFEHEMEESKKNRVEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADK
       : :  :: ::  .: :::. .::..: .:........: ::.:    .. ...:: ::..
CCDS34 AASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQ
            70        80        90       100       110       120   

     280       290       300       310       320       330         
pF1KE3 YALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDG
       : .: .: :: . :  .... :     :::.  .  .::: : :::..            
CCDS34 YQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFL
           130       140       150       160       170       180   

     340       350       360       370       380       390         
pF1KE3 KNWNSNQATDIMETSGWKSMIQSHPHLVAEAFRALASAQCPQFGIPRKRLKQS       
                                                                   
CCDS34 QLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFL
           190       200       210       220       230       240   

>>CCDS47418.1 BTBD9 gene_id:114781|Hs108|chr6             (612 aa)
 initn:  85 init1:  85 opt: 259  Z-score: 314.9  bits: 67.7 E(32554): 3.2e-11
Smith-Waterman score: 259; 32.2% identity (63.7% similar) in 146 aa overlap (186-327:22-167)

         160       170       180       190       200       210     
pF1KE3 TLFCEVSVVQDSVNISGHTNTNTLKVPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHK
                                     :.: .: :  . .. : .: :. ..: ::.
CCDS47          MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHR
                        10        20        30        40        50 

         220       230        240       250       260       270    
pF1KE3 SVLAARSPVFNAMFEHEMEESK-KNRVEINDLDPEVFKEMMRFIYTGRAPNLDKMAD---
        .::::   : :..   :.::. . .. ..:   :.:  ....::::::   :.  .   
CCDS47 VILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLL
              60        70        80        90       100       110 

             280       290       300       310       320       330 
pF1KE3 NLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQAIDFINRCSVL
       ..:. : ::.. .:.    : ::. :...::  :. .:.:.:  .:  .   :..:    
CCDS47 DFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQE
             120       130       140       150       160       170 

             340       350       360       370       380       390 
pF1KE3 RQLGCKDGKNWNSNQATDIMETSGWKSMIQSHPHLVAEAFRALASAQCPQFGIPRKRLKQ
                                                                   
CCDS47 VLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMS
             180       190       200       210       220       230 




392 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 08:24:21 2016 done: Sun Nov  6 08:24:21 2016
 Total Scan time:  2.610 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]