Result of FASTA (omim) for
pFN21AE3402
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3402, 149 aa
1>>>pF1KE3402 149 - 149 aa - 149 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4176+/-0.000325; mu= 12.3620+/- 0.020
mean_var=143.1169+/-36.614, 0's: 0 Z-trim(117.9): 133 B-trim: 1448 in 1/48
Lambda= 0.107208
statistics sampled from 29971 (30277) to 29971 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.355), width: 16
Scan time: 4.840
The best scores are: opt bits E(85289)
NP_068734 (OMIM: 194543) zinc finger protein 69 is ( 149) 1042 171.8 3.6e-43
NP_001308092 (OMIM: 194543) zinc finger protein 69 ( 163) 877 146.4 1.8e-35
XP_016882720 (OMIM: 194543) PREDICTED: zinc finger ( 166) 877 146.4 1.8e-35
XP_006722937 (OMIM: 194543) PREDICTED: zinc finger ( 166) 877 146.4 1.8e-35
XP_006722936 (OMIM: 194543) PREDICTED: zinc finger ( 569) 877 147.1 3.7e-35
NP_001190179 (OMIM: 194557) zinc finger protein 20 ( 529) 538 94.6 2.2e-19
NP_066966 (OMIM: 194557) zinc finger protein 20 is ( 532) 538 94.6 2.2e-19
NP_660338 (OMIM: 612248) zinc finger protein 627 i ( 461) 448 80.6 3.1e-15
NP_003428 (OMIM: 604078) zinc finger protein 136 [ ( 540) 409 74.7 2.2e-13
XP_016881628 (OMIM: 606697) PREDICTED: zinc finger ( 685) 375 69.6 9.8e-12
XP_011525925 (OMIM: 606697) PREDICTED: zinc finger ( 718) 375 69.6 1e-11
NP_005806 (OMIM: 606697) zinc finger protein 443 [ ( 671) 374 69.4 1.1e-11
XP_016881629 (OMIM: 606697) PREDICTED: zinc finger ( 673) 374 69.4 1.1e-11
NP_057348 (OMIM: 194542) zinc finger protein 44 is ( 615) 367 68.3 2.2e-11
XP_011526366 (OMIM: 194542) PREDICTED: zinc finger ( 616) 367 68.3 2.2e-11
XP_011526364 (OMIM: 194542) PREDICTED: zinc finger ( 653) 367 68.3 2.3e-11
NP_001157748 (OMIM: 194542) zinc finger protein 44 ( 663) 367 68.3 2.3e-11
NP_001277012 (OMIM: 612248) zinc finger protein 62 ( 429) 360 67.0 3.7e-11
XP_011526082 (OMIM: 612248) PREDICTED: zinc finger ( 429) 360 67.0 3.7e-11
NP_066358 (OMIM: 194556) zinc finger protein 14 [H ( 642) 352 66.0 1.1e-10
NP_149981 (OMIM: 603983) zinc finger protein 101 i ( 436) 349 65.3 1.2e-10
XP_011526571 (OMIM: 604078) PREDICTED: zinc finger ( 508) 321 61.1 2.7e-09
XP_011525924 (OMIM: 606697) PREDICTED: zinc finger ( 639) 301 58.1 2.6e-08
XP_016882359 (OMIM: 194542) PREDICTED: zinc finger ( 583) 291 56.5 7.3e-08
XP_011542574 (OMIM: 194631) PREDICTED: zinc finger ( 343) 260 51.4 1.5e-06
NP_001284497 (OMIM: 194631) zinc finger protein 12 ( 351) 260 51.4 1.5e-06
XP_011526368 (OMIM: 194542) PREDICTED: zinc finger ( 571) 248 49.8 7.2e-06
NP_003422 (OMIM: 194631) zinc finger protein 124 i ( 289) 238 47.9 1.4e-05
NP_001284498 (OMIM: 194631) zinc finger protein 12 ( 93) 212 43.2 0.00012
NP_001230669 (OMIM: 194631) zinc finger protein 12 ( 73) 210 42.7 0.00013
NP_001284496 (OMIM: 194631) zinc finger protein 12 ( 77) 210 42.7 0.00013
XP_016882732 (OMIM: 604078) PREDICTED: zinc finger ( 474) 189 40.6 0.0036
>>NP_068734 (OMIM: 194543) zinc finger protein 69 isofor (149 aa)
initn: 1042 init1: 1042 opt: 1042 Z-score: 896.1 bits: 171.8 E(85289): 3.6e-43
Smith-Waterman score: 1042; 100.0% identity (100.0% similar) in 149 aa overlap (1-149:1-149)
10 20 30 40 50 60
pF1KE3 MPCCSHRRCREDPGTSESQEMEEWALLDISQRKLYKEVMLETFRNLTSVGKSWKDQNIEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MPCCSHRRCREDPGTSESQEMEEWALLDISQRKLYKEVMLETFRNLTSVGKSWKDQNIEY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEKKASPEIKSCDSFVCGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 EYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEKKASPEIKSCDSFVCGEV
70 80 90 100 110 120
130 140
pF1KE3 GLGNSSFNMNIRGDIGHKAYEYQEYGPKP
:::::::::::::::::::::::::::::
NP_068 GLGNSSFNMNIRGDIGHKAYEYQEYGPKP
130 140
>>NP_001308092 (OMIM: 194543) zinc finger protein 69 iso (163 aa)
initn: 1041 init1: 877 opt: 877 Z-score: 757.8 bits: 146.4 E(85289): 1.8e-35
Smith-Waterman score: 1004; 91.4% identity (91.4% similar) in 163 aa overlap (1-149:1-163)
10 20 30 40
pF1KE3 MPCCSHRRCREDPGTSESQEM--------------EEWALLDISQRKLYKEVMLETFRNL
::::::::::::::::::::: :::::::::::::::::::::::::
NP_001 MPCCSHRRCREDPGTSESQEMDPVAFDDVAVNFTQEEWALLDISQRKLYKEVMLETFRNL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 TSVGKSWKDQNIEYEYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEKKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSVGKSWKDQNIEYEYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEKKAS
70 80 90 100 110 120
110 120 130 140
pF1KE3 PEIKSCDSFVCGEVGLGNSSFNMNIRGDIGHKAYEYQEYGPKP
:::::::::::::::::::::::::::::::::::::::::::
NP_001 PEIKSCDSFVCGEVGLGNSSFNMNIRGDIGHKAYEYQEYGPKP
130 140 150 160
>>XP_016882720 (OMIM: 194543) PREDICTED: zinc finger pro (166 aa)
initn: 1028 init1: 877 opt: 877 Z-score: 757.7 bits: 146.4 E(85289): 1.8e-35
Smith-Waterman score: 998; 89.8% identity (89.8% similar) in 166 aa overlap (1-149:1-166)
10 20 30 40
pF1KE3 MPCCSHRRCREDPGTSESQEM-----------------EEWALLDISQRKLYKEVMLETF
::::::::::::::::::::: ::::::::::::::::::::::
XP_016 MPCCSHRRCREDPGTSESQEMMFQDPVAFDDVAVNFTQEEWALLDISQRKLYKEVMLETF
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RNLTSVGKSWKDQNIEYEYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNLTSVGKSWKDQNIEYEYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEK
70 80 90 100 110 120
110 120 130 140
pF1KE3 KASPEIKSCDSFVCGEVGLGNSSFNMNIRGDIGHKAYEYQEYGPKP
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASPEIKSCDSFVCGEVGLGNSSFNMNIRGDIGHKAYEYQEYGPKP
130 140 150 160
>>XP_006722937 (OMIM: 194543) PREDICTED: zinc finger pro (166 aa)
initn: 1028 init1: 877 opt: 877 Z-score: 757.7 bits: 146.4 E(85289): 1.8e-35
Smith-Waterman score: 998; 89.8% identity (89.8% similar) in 166 aa overlap (1-149:1-166)
10 20 30 40
pF1KE3 MPCCSHRRCREDPGTSESQEM-----------------EEWALLDISQRKLYKEVMLETF
::::::::::::::::::::: ::::::::::::::::::::::
XP_006 MPCCSHRRCREDPGTSESQEMMFQDPVAFDDVAVNFTQEEWALLDISQRKLYKEVMLETF
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RNLTSVGKSWKDQNIEYEYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RNLTSVGKSWKDQNIEYEYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEK
70 80 90 100 110 120
110 120 130 140
pF1KE3 KASPEIKSCDSFVCGEVGLGNSSFNMNIRGDIGHKAYEYQEYGPKP
::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KASPEIKSCDSFVCGEVGLGNSSFNMNIRGDIGHKAYEYQEYGPKP
130 140 150 160
>>XP_006722936 (OMIM: 194543) PREDICTED: zinc finger pro (569 aa)
initn: 1028 init1: 877 opt: 877 Z-score: 752.1 bits: 147.1 E(85289): 3.7e-35
Smith-Waterman score: 998; 89.8% identity (89.8% similar) in 166 aa overlap (1-149:1-166)
10 20 30 40
pF1KE3 MPCCSHRRCREDPGTSESQEM-----------------EEWALLDISQRKLYKEVMLETF
::::::::::::::::::::: ::::::::::::::::::::::
XP_006 MPCCSHRRCREDPGTSESQEMMFQDPVAFDDVAVNFTQEEWALLDISQRKLYKEVMLETF
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RNLTSVGKSWKDQNIEYEYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RNLTSVGKSWKDQNIEYEYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEK
70 80 90 100 110 120
110 120 130 140
pF1KE3 KASPEIKSCDSFVCGEVGLGNSSFNMNIRGDIGHKAYEYQEYGPKP
::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KASPEIKSCDSFVCGEVGLGNSSFNMNIRGDIGHKAYEYQEYGPKPCKCQQPKKAFRYHP
130 140 150 160 170 180
XP_006 SFRTPQRDHTGEKPYACKECGKTFISHSSIQRHVVMHSGDGPYKCKFCGKAFHCLSLYLI
190 200 210 220 230 240
>>NP_001190179 (OMIM: 194557) zinc finger protein 20 iso (529 aa)
initn: 407 init1: 256 opt: 538 Z-score: 469.1 bits: 94.6 E(85289): 2.2e-19
Smith-Waterman score: 538; 59.7% identity (80.6% similar) in 139 aa overlap (11-149:7-139)
10 20 30 40 50 60
pF1KE3 MPCCSHRRCREDPGTSESQEMEEWALLDISQRKLYKEVMLETFRNLTSVGKSWKDQNIEY
:: ..: .:: :::::: ::..::..:: :::.:::::::.:: ::::
NP_001 MDSVAFEDVAVSFTQE--EWALLDPSQKNLYRDVMQETFKNLTSVGKTWKVQNIED
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 EYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEKKASPEIKSCDSFVCGEV
::.:::::. ::...:. : :.. ::::.:.:. :: :: .:. : : :.: :::::
NP_001 EYKNPRRNL-SLMREKLCESKESHHCGESFNQIADDMLN---RKTLPGITPCESSVCGEV
60 70 80 90 100 110
130 140
pF1KE3 GLGNSSFNMNIRGDIGHKAYEYQEYGPKP
: :.::.: .::.: :::. :::::: .:
NP_001 GTGHSSLNTHIRADTGHKSSEYQEYGENPYRNKECKKAFSYLDSFQSHDKACTKEKPYDG
120 130 140 150 160 170
>>NP_066966 (OMIM: 194557) zinc finger protein 20 isofor (532 aa)
initn: 407 init1: 256 opt: 538 Z-score: 469.0 bits: 94.6 E(85289): 2.2e-19
Smith-Waterman score: 538; 59.7% identity (80.6% similar) in 139 aa overlap (11-149:10-142)
10 20 30 40 50 60
pF1KE3 MPCCSHRRCREDPGTSESQEMEEWALLDISQRKLYKEVMLETFRNLTSVGKSWKDQNIEY
:: ..: .:: :::::: ::..::..:: :::.:::::::.:: ::::
NP_066 MMFQDSVAFEDVAVSFTQE--EWALLDPSQKNLYRDVMQETFKNLTSVGKTWKVQNIED
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 EYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEKKASPEIKSCDSFVCGEV
::.:::::. ::...:. : :.. ::::.:.:. :: :: .:. : : :.: :::::
NP_066 EYKNPRRNL-SLMREKLCESKESHHCGESFNQIADDMLN---RKTLPGITPCESSVCGEV
60 70 80 90 100 110
130 140
pF1KE3 GLGNSSFNMNIRGDIGHKAYEYQEYGPKP
: :.::.: .::.: :::. :::::: .:
NP_066 GTGHSSLNTHIRADTGHKSSEYQEYGENPYRNKECKKAFSYLDSFQSHDKACTKEKPYDG
120 130 140 150 160 170
>>NP_660338 (OMIM: 612248) zinc finger protein 627 isofo (461 aa)
initn: 399 init1: 236 opt: 448 Z-score: 394.4 bits: 80.6 E(85289): 3.1e-15
Smith-Waterman score: 448; 54.7% identity (75.8% similar) in 128 aa overlap (21-148:15-137)
10 20 30 40 50 60
pF1KE3 MPCCSHRRCREDPGTSESQEMEEWALLDISQRKLYKEVMLETFRNLTSVGKSWKDQNIEY
.::::::: ::..::..:: ::::::.::::.:.:::::
NP_660 MDSVAFEDVAVNFTLEEWALLDPSQKNLYRDVMRETFRNLASVGKQWEDQNIED
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 EYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEKKASPEIKSCDSFVCGEV
.. ::::. : : ... : :. .. :::.:.:: :: : .: .: :.: :::::
NP_660 PFKIPRRNI-SHIPERLCESKEGGQGEETFSQIPDGILN----KKTPGVKPCESSVCGEV
60 70 80 90 100
130 140
pF1KE3 GLGNSSFNMNIRGDIGHKAYEYQEYGPKP
:.: ::.: .:: :.. :::::: :
NP_660 GMGPSSLNRHIRDHTGREPNEYQEYGKKSYTRNQCGRALSYHRSFPVRERTHPGGKPYDC
110 120 130 140 150 160
>>NP_003428 (OMIM: 604078) zinc finger protein 136 [Homo (540 aa)
initn: 410 init1: 262 opt: 409 Z-score: 361.1 bits: 74.7 E(85289): 2.2e-13
Smith-Waterman score: 409; 47.5% identity (73.4% similar) in 139 aa overlap (11-149:7-139)
10 20 30 40 50 60
pF1KE3 MPCCSHRRCREDPGTSESQEMEEWALLDISQRKLYKEVMLETFRNLTSVGKSWKDQNIEY
:: .. .:: :::::: ::..::..:: ::.:::.:.::.::::::.
NP_003 MDSVAFEDVDVNFTQE--EWALLDPSQKNLYRDVMWETMRNLASIGKKWKDQNIKD
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 EYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQVPDDRLNFQEKKASPEIKSCDSFVCGEV
.:.. ::.:: . ... . :: :. : :.: .. :. : : .: :.:.: :::
NP_003 HYKHRGRNLRSHMLERLYQTKDGSQRGGIFSQFANQNLS----KKIPGVKLCESIVYGEV
60 70 80 90 100 110
130 140
pF1KE3 GLGNSSFNMNIRGDIGHKAYEYQEYGPKP
..:.::.: .:. ::. :::::: ::
NP_003 SMGQSSLNRHIKDHSGHEPKEYQEYGEKPDTRNQCWKPFSSHHSFRTHEIIHTGEKLYDC
120 130 140 150 160 170
>>XP_016881628 (OMIM: 606697) PREDICTED: zinc finger pro (685 aa)
initn: 354 init1: 263 opt: 375 Z-score: 331.6 bits: 69.6 E(85289): 9.8e-12
Smith-Waterman score: 375; 43.2% identity (66.4% similar) in 146 aa overlap (4-149:47-187)
10 20 30
pF1KE3 MPCCSHRRCREDPGTSESQEMEEWALLDISQRK
:. :: ... .. :::::: :..
XP_016 SDPPASASQNTGIIGVSHHAQPKTLNLEEHCKASVALEDVAVNFTR--EEWALLGPCQKN
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE3 LYKEVMLETFRNLTSVGKSWKDQNIEYEYQNPRRNFRSLIEKKVNEIKDDSHCGETFTQV
:::.:: ::.::: : .::::::: .:. ::.:.: . .. : :: ..:::: .:.
XP_016 LYKDVMQETIRNLDCVVMKWKDQNIEDQYRYPRKNLRCRMLERFVESKDGTQCGETSSQI
80 90 100 110 120 130
100 110 120 130 140
pF1KE3 PDDRLNFQEKKASPEIKSCDSFVCGEVGLGNSSFNMNIRGDIGHKAYEYQEYGPKP
: .. :.. : . :.: . :: .:.::.: :: ::: .::.: : ::
XP_016 QD---SIVTKNTLPGVGPCESSMRGEKVMGHSSLNCYIRVGAGHKPHEYHECGEKPDTHK
140 150 160 170 180 190
XP_016 QRGKAFSYHNSFQTHERLHTGKKPYDCKECGKSFSSLGNLQRHMAVQRGDGPYKCKLCGK
200 210 220 230 240 250
149 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:11:41 2016 done: Sun Nov 6 05:11:42 2016
Total Scan time: 4.840 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]