Result of FASTA (omim) for
pFN21AE6380
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6380, 317 aa
1>>>pF1KE6380 317 - 317 aa - 317 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0432+/-0.000354; mu= 13.0260+/- 0.022
mean_var=90.8899+/-18.237, 0's: 0 Z-trim(115.2): 25 B-trim: 0 in 0/53
Lambda= 0.134529
statistics sampled from 25418 (25442) to 25418 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.298), width: 16
Scan time: 5.590
The best scores are: opt bits E(85289)
XP_011520172 (OMIM: 136880,180090,607475,607476) P ( 317) 2098 417.1 2.4e-116
NP_000317 (OMIM: 136880,180090,607475,607476) reti ( 317) 2098 417.1 2.4e-116
XP_016877949 (OMIM: 136880,180090,607475,607476) P ( 326) 2074 412.5 6.1e-115
XP_016868630 (OMIM: 611292) PREDICTED: clavesin-1 ( 354) 689 143.7 5.4e-34
NP_775790 (OMIM: 611292) clavesin-1 [Homo sapiens] ( 354) 689 143.7 5.4e-34
XP_016868631 (OMIM: 611292) PREDICTED: clavesin-1 ( 354) 689 143.7 5.4e-34
XP_016865755 (OMIM: 616945) PREDICTED: clavesin-2 ( 327) 670 140.0 6.5e-33
NP_001010852 (OMIM: 616945) clavesin-2 [Homo sapie ( 327) 670 140.0 6.5e-33
NP_000361 (OMIM: 277460,600415) alpha-tocopherol t ( 278) 441 95.5 1.4e-19
NP_002824 (OMIM: 600768) tyrosine-protein phosphat ( 593) 296 67.5 7.5e-11
XP_006716531 (OMIM: 277460,600415) PREDICTED: alph ( 162) 178 44.3 0.00021
NP_001191133 (OMIM: 607558) SEC14-like protein 2 i ( 320) 165 41.9 0.0021
NP_001244308 (OMIM: 612824) SEC14-like protein 3 i ( 341) 157 40.4 0.0063
NP_001244311 (OMIM: 612824) SEC14-like protein 3 i ( 341) 157 40.4 0.0063
XP_006724298 (OMIM: 612825) PREDICTED: SEC14-like ( 352) 154 39.8 0.0097
XP_016884278 (OMIM: 612825) PREDICTED: SEC14-like ( 352) 154 39.8 0.0097
XP_016884280 (OMIM: 612825) PREDICTED: SEC14-like ( 352) 154 39.8 0.0097
>>XP_011520172 (OMIM: 136880,180090,607475,607476) PREDI (317 aa)
initn: 2098 init1: 2098 opt: 2098 Z-score: 2209.9 bits: 417.1 E(85289): 2.4e-116
Smith-Waterman score: 2098; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317)
10 20 30 40 50 60
pF1KE6 MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 CFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 IHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKA
250 260 270 280 290 300
310
pF1KE6 VAEQLFGPQAQAENTAF
:::::::::::::::::
XP_011 VAEQLFGPQAQAENTAF
310
>>NP_000317 (OMIM: 136880,180090,607475,607476) retinald (317 aa)
initn: 2098 init1: 2098 opt: 2098 Z-score: 2209.9 bits: 417.1 E(85289): 2.4e-116
Smith-Waterman score: 2098; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317)
10 20 30 40 50 60
pF1KE6 MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 CFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 IHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKA
250 260 270 280 290 300
310
pF1KE6 VAEQLFGPQAQAENTAF
:::::::::::::::::
NP_000 VAEQLFGPQAQAENTAF
310
>>XP_016877949 (OMIM: 136880,180090,607475,607476) PREDI (326 aa)
initn: 2074 init1: 2074 opt: 2074 Z-score: 2184.5 bits: 412.5 E(85289): 6.1e-115
Smith-Waterman score: 2074; 99.4% identity (99.4% similar) in 316 aa overlap (2-317:11-326)
10 20 30 40 50
pF1KE6 MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDE
: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRLAVPLFPFSAQVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 LNEREETREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNEREETREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAY
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 ELLRGYVNFRLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLRGYVNFRLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 TFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSF
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 PARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGG
250 260 270 280 290 300
300 310
pF1KE6 TLPKYDGKAVAEQLFGPQAQAENTAF
::::::::::::::::::::::::::
XP_016 TLPKYDGKAVAEQLFGPQAQAENTAF
310 320
>>XP_016868630 (OMIM: 611292) PREDICTED: clavesin-1 isof (354 aa)
initn: 704 init1: 569 opt: 689 Z-score: 731.3 bits: 143.7 E(85289): 5.4e-34
Smith-Waterman score: 689; 39.2% identity (71.6% similar) in 278 aa overlap (40-314:30-296)
10 20 30 40 50 60
pF1KE6 MVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEM
: .:..::. :::: .. .. ......:
XP_016 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDM
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 VQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFD
. .. : . :..:.:::.:::::. . :..:: : ..: ..:
XP_016 IITRPDIG----------FLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFK
60 70 80 90 100
130 140 150 160 170 180
pF1KE6 SLS---PEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEK
... : : :. :.:::: .::.::: ..:. ::.... .: .::.: . ::
XP_016 NFKADDPGIKRALID-GFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE6 LLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWY
:.:. : ::::: .: ....:...::..: : :. .. ::::::::: ..::..::::
XP_016 LIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE6 FTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLF
. . :...:::::.: .:.:.::..:....: : ..:::.:::::: :: . :. :.
XP_016 IHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLL
230 240 250 260 270 280
310
pF1KE6 GPQAQAENTAF
::. . ::
XP_016 GPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQ
290 300 310 320 330 340
>>NP_775790 (OMIM: 611292) clavesin-1 [Homo sapiens] (354 aa)
initn: 704 init1: 569 opt: 689 Z-score: 731.3 bits: 143.7 E(85289): 5.4e-34
Smith-Waterman score: 689; 39.2% identity (71.6% similar) in 278 aa overlap (40-314:30-296)
10 20 30 40 50 60
pF1KE6 MVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEM
: .:..::. :::: .. .. ......:
NP_775 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDM
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 VQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFD
. .. : . :..:.:::.:::::. . :..:: : ..: ..:
NP_775 IITRPDIG----------FLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFK
60 70 80 90 100
130 140 150 160 170 180
pF1KE6 SLS---PEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEK
... : : :. :.:::: .::.::: ..:. ::.... .: .::.: . ::
NP_775 NFKADDPGIKRALID-GFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE6 LLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWY
:.:. : ::::: .: ....:...::..: : :. .. ::::::::: ..::..::::
NP_775 LIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE6 FTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLF
. . :...:::::.: .:.:.::..:....: : ..:::.:::::: :: . :. :.
NP_775 IHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLL
230 240 250 260 270 280
310
pF1KE6 GPQAQAENTAF
::. . ::
NP_775 GPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQ
290 300 310 320 330 340
>>XP_016868631 (OMIM: 611292) PREDICTED: clavesin-1 isof (354 aa)
initn: 704 init1: 569 opt: 689 Z-score: 731.3 bits: 143.7 E(85289): 5.4e-34
Smith-Waterman score: 689; 39.2% identity (71.6% similar) in 278 aa overlap (40-314:30-296)
10 20 30 40 50 60
pF1KE6 MVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEM
: .:..::. :::: .. .. ......:
XP_016 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDM
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 VQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFD
. .. : . :..:.:::.:::::. . :..:: : ..: ..:
XP_016 IITRPDIG----------FLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFK
60 70 80 90 100
130 140 150 160 170 180
pF1KE6 SLS---PEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEK
... : : :. :.:::: .::.::: ..:. ::.... .: .::.: . ::
XP_016 NFKADDPGIKRALID-GFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEV
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE6 LLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWY
:.:. : ::::: .: ....:...::..: : :. .. ::::::::: ..::..::::
XP_016 LIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWY
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE6 FTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLF
. . :...:::::.: .:.:.::..:....: : ..:::.:::::: :: . :. :.
XP_016 IHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLL
230 240 250 260 270 280
310
pF1KE6 GPQAQAENTAF
::. . ::
XP_016 GPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQ
290 300 310 320 330 340
>>XP_016865755 (OMIM: 616945) PREDICTED: clavesin-2 isof (327 aa)
initn: 660 init1: 526 opt: 670 Z-score: 711.8 bits: 140.0 E(85289): 6.5e-33
Smith-Waterman score: 670; 39.4% identity (71.7% similar) in 269 aa overlap (40-306:8-266)
10 20 30 40 50 60
pF1KE6 MVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEM
: .::.::. :::: .: .. ..:...:
XP_016 MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDM
10 20 30
70 80 90 100 110 120
pF1KE6 VQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFD
: .. : . :..:.:::.:::::. .:..:: : ..: : ..:
XP_016 VITRPDIG----------FLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFK
40 50 60 70 80
130 140 150 160 170 180
pF1KE6 SL--SPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEKL
:. . ... ... :.:: :.. :.::: .... ::.... :. .::.: . :: .
XP_016 SFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAM
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE6 LENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWYF
.:. : :.::: .: ....::..::..: : :: .. ::::::::: .:::..::::.
XP_016 IEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYI
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE6 TTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLFG
. :.:..:::: : .:.:.::..:....: : .::::.::: :: :: . :. :.
XP_016 HALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLD
210 220 230 240 250 260
310
pF1KE6 PQAQAENTAF
XP_016 HEYDDDSEYNVDSYSMPVKEVEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD
270 280 290 300 310 320
>>NP_001010852 (OMIM: 616945) clavesin-2 [Homo sapiens] (327 aa)
initn: 660 init1: 526 opt: 670 Z-score: 711.8 bits: 140.0 E(85289): 6.5e-33
Smith-Waterman score: 670; 39.4% identity (71.7% similar) in 269 aa overlap (40-306:8-266)
10 20 30 40 50 60
pF1KE6 MVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEM
: .::.::. :::: .: .. ..:...:
NP_001 MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDM
10 20 30
70 80 90 100 110 120
pF1KE6 VQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFD
: .. : . :..:.:::.:::::. .:..:: : ..: : ..:
NP_001 VITRPDIG----------FLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFK
40 50 60 70 80
130 140 150 160 170 180
pF1KE6 SL--SPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEKL
:. . ... ... :.:: :.. :.::: .... ::.... :. .::.: . :: .
NP_001 SFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAM
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE6 LENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWYF
.:. : :.::: .: ....::..::..: : :: .. ::::::::: .:::..::::.
NP_001 IEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYI
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE6 TTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLFG
. :.:..:::: : .:.:.::..:....: : .::::.::: :: :: . :. :.
NP_001 HALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLD
210 220 230 240 250 260
310
pF1KE6 PQAQAENTAF
NP_001 HEYDDDSEYNVDSYSMPVKEVEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD
270 280 290 300 310 320
>>NP_000361 (OMIM: 277460,600415) alpha-tocopherol trans (278 aa)
initn: 437 init1: 437 opt: 441 Z-score: 472.7 bits: 95.5 E(85289): 1.4e-19
Smith-Waterman score: 441; 32.7% identity (66.8% similar) in 226 aa overlap (66-291:24-247)
40 50 60 70 80 90
pF1KE6 PCSQLPRHTLQKAKDELNEREETREEAVRELQEMVQAQAASGEELAVAVAERVQEKDSGF
:: . : ..: .: .: . :: :
NP_000 MAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAP-LPLTDS-F
10 20 30 40 50
100 110 120 130 140 150
pF1KE6 FLRFIRARKFNVGRAYELLRGYVNFRLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYG
.:::.::: :.. :..::..: ..: . ::. .: :... ..::: ::: ::: :
NP_000 LLRFLRARDFDLDLAWRLLKNYYKWRAECPEISADLHPRSIIGLLKAGYHGVLRSRDPTG
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE6 RVVMLFNIENWQSQEITFDEILQAYCFILEKLLENEETQINGFCIIENFKGFTMQQAASL
:... : .:. . .: ..... . : .... ::: ::. : ...:. ...: ..
NP_000 SKVLIYRIAHWDPKVFTAYDVFRVSLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQI
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE6 RTSDLRKMVDMLQDSFPARFKAIHFIHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSG
: .:.. .: :::: . ..::.:..: : ......:::: :. ::. .::.. .
NP_000 TPSVAKKIAAVLTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQ
180 190 200 210 220 230
280 290 300 310
pF1KE6 FYQEIDENILPSDFGGTLPKYDGKAVAEQLFGPQAQAENTAF
. .::: ..::
NP_000 SLLQHFPDILPLEYGGEEFSMEDICQEWTNFIMKSEDYLSSISESIQ
240 250 260 270
>>NP_002824 (OMIM: 600768) tyrosine-protein phosphatase (593 aa)
initn: 328 init1: 161 opt: 296 Z-score: 315.8 bits: 67.5 E(85289): 7.5e-11
Smith-Waterman score: 296; 29.1% identity (62.8% similar) in 223 aa overlap (97-317:48-261)
70 80 90 100 110 120
pF1KE6 QEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPE
..:. ::::.: :: ::...: . : . :
NP_002 EEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRRK--E
20 30 40 50 60 70
130 140 150 160 170 180
pF1KE6 LFDSLSP--EAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFIL
. .:.: : .: : .: .:. :: : . ::. . . .. . .::: ..:
NP_002 GIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLL
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE6 EKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQP
.. ... ::: ::. .: .. : .. :... . .:....:. .::::.: . .. :
NP_002 DRAVDSFETQRNGLVFIYDMCG---SNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAP
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE6 WYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQ
.: . :.... .::.:. ::. . : :.. .. :: ..:: . : : . :
NP_002 IWFRVPYSIISLLLKDKVRERIQIL--KTSEVTQHLPRECLPENLGGYV-KIDLATWNFQ
200 210 220 230 240
310
pF1KE6 LFGPQAQAENTAF
: ::.... :
NP_002 -FLPQVNGHPDPFDEIILFSLPPALDWDSVHVPGPHAMTIQELVDYVNARQKQGIYEEYE
250 260 270 280 290 300
317 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:44:51 2016 done: Tue Nov 8 12:44:52 2016
Total Scan time: 5.590 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]