Result of FASTA (omim) for
pFN21AE1163
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1163, 580 aa
1>>>pF1KE1163 580 - 580 aa - 580 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4003+/-0.000355; mu= 9.4196+/- 0.022
mean_var=115.7482+/-23.668, 0's: 0 Z-trim(116.8): 7 B-trim: 1004 in 2/54
Lambda= 0.119211
statistics sampled from 28204 (28211) to 28204 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.331), width: 16
Scan time: 10.800
The best scores are: opt bits E(85289)
NP_062826 (OMIM: 612472) N6-adenosine-methyltransf ( 580) 3903 682.3 1.1e-195
XP_011535270 (OMIM: 612472) PREDICTED: N6-adenosin ( 558) 3247 569.5 1e-161
XP_006720269 (OMIM: 612472) PREDICTED: N6-adenosin ( 296) 2100 372.1 1.4e-102
NP_066012 (OMIM: 616504) N6-adenosine-methyltransf ( 456) 255 54.9 6.8e-07
XP_005263223 (OMIM: 616504) PREDICTED: N6-adenosin ( 314) 208 46.7 0.00013
>>NP_062826 (OMIM: 612472) N6-adenosine-methyltransferas (580 aa)
initn: 3903 init1: 3903 opt: 3903 Z-score: 3633.9 bits: 682.3 E(85289): 1.1e-195
Smith-Waterman score: 3903; 99.8% identity (100.0% similar) in 580 aa overlap (1-580:1-580)
10 20 30 40 50 60
pF1KE1 MSDTWSSIQAHKKQLDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 MSDTWSSIQAHKKQLDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSICLAISTPDAPATQDGVESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 PKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSICLAISTPDAPATQDGVESLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 QKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 EQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 KVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 KVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 RIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 RIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 GDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 GDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 VLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 VLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 EHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 EHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNV
490 500 510 520 530 540
550 560 570 580
pF1KE1 QPNWITLGNQLDGIHLLDPDVVARFKQKYPDGIISKPKNL
:::::::::::::::::::::::::::.::::::::::::
NP_062 QPNWITLGNQLDGIHLLDPDVVARFKQRYPDGIISKPKNL
550 560 570 580
>>XP_011535270 (OMIM: 612472) PREDICTED: N6-adenosine-me (558 aa)
initn: 3247 init1: 3247 opt: 3247 Z-score: 3024.4 bits: 569.5 E(85289): 1e-161
Smith-Waterman score: 3695; 96.0% identity (96.2% similar) in 580 aa overlap (1-580:1-558)
10 20 30 40 50 60
pF1KE1 MSDTWSSIQAHKKQLDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSDTWSSIQAHKKQLDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSICLAISTPDAPATQDGVESLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSICLAISTPDAPATQDGVESLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 QKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 KVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 RIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 GDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 VLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE1 EHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNV
::::: :::::::::::::::::::::::::::::::::
XP_011 EHCLV----------------------RSTSHKPDEIYGMIERLSPGTRKIELFGRPHNV
490 500 510
550 560 570 580
pF1KE1 QPNWITLGNQLDGIHLLDPDVVARFKQKYPDGIISKPKNL
:::::::::::::::::::::::::::.::::::::::::
XP_011 QPNWITLGNQLDGIHLLDPDVVARFKQRYPDGIISKPKNL
520 530 540 550
>>XP_006720269 (OMIM: 612472) PREDICTED: N6-adenosine-me (296 aa)
initn: 2100 init1: 2100 opt: 2100 Z-score: 1962.7 bits: 372.1 E(85289): 1.4e-102
Smith-Waterman score: 2100; 99.7% identity (100.0% similar) in 296 aa overlap (285-580:1-296)
260 270 280 290 300 310
pF1KE1 AKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDC
::::::::::::::::::::::::::::::
XP_006 MKASDADRPCRKLHFRRIINKHTDESLGDC
10 20 30
320 330 340 350 360 370
pF1KE1 SFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVGGDSSADRLFPPQWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVGGDSSADRLFPPQWI
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE1 CCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGFLFLWVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGFLFLWVTG
100 110 120 130 140 150
440 450 460 470 480 490
pF1KE1 RAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGF
160 170 180 190 200 210
500 510 520 530 540 550
pF1KE1 NQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGI
220 230 240 250 260 270
560 570 580
pF1KE1 HLLDPDVVARFKQKYPDGIISKPKNL
:::::::::::::.::::::::::::
XP_006 HLLDPDVVARFKQRYPDGIISKPKNL
280 290
>>NP_066012 (OMIM: 616504) N6-adenosine-methyltransferas (456 aa)
initn: 386 init1: 129 opt: 255 Z-score: 244.8 bits: 54.9 E(85289): 6.8e-07
Smith-Waterman score: 366; 26.7% identity (55.8% similar) in 371 aa overlap (207-551:9-364)
180 190 200 210 220 230
pF1KE1 KRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLE----IESLLNQQ
.: : :. :... : : ..::
NP_066 MDSRLQEIRERQKLRRQLLAQQLGAESADSIGAVLN--
10 20 30
240 250 260 270 280 290
pF1KE1 STKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADR
: ::. ..: . :.: . . .:. ..:... ... .: . : :. .. .
NP_066 SKDEQREIAETRETCRASYDTSAPNAK--RKYLDEGETDEDKMEEYKDELE-MQQDEENL
40 50 60 70 80 90
300 310 320 330 340
pF1KE1 PCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYV----HYEIDACMDSEAPGSKDHT
: ... : : .. : . :: : : :.. : . : ..
NP_066 P-----YEEEIYKDSSTFLKGTQSLNP--HNDYCQHFVDTGHRPQNFIRDVGLADRFEEY
100 110 120 130 140
350 360 370 380 390 400
pF1KE1 PS-QELALTQSVGGDSSADRLFPPQWICCDIRYLDVSILG-KFAVVMADPPWDIHMELPY
:. .:: .. . : ::... ::. .:. : :: :.. .:: . ...
NP_066 PKLRELIRLKD---ELIAKSNTPPMYLQADIEAFDIRELTPKFDVILLEPPLEEYYRETG
150 160 170 180 190 200
410 420 430 440 450
pF1KE1 GTLTD-----DEMRRLNIP-VLQDDGFLFLWV-TGRAMELGRECLNLWGYERVDEIIWVK
: .. :.. .:.: . .:.::: .:....::: :: :::.: ..: :.:
NP_066 ITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEGLDLGRVCLRKWGYRRCEDICWIK
210 220 230 240 250 260
460 470 480 490 500 510
pF1KE1 TNQLQR-IIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQG------LDCDVIVAEVRSTSH
::. . .: ... :::::.:.::. . ..: .: :.:..: ..
NP_066 TNKNNPGKTKTLDPKAVFQRTKEHCLMGIKGTVKRSTDGDFIHANVDIDLIITEEPEIGN
270 280 290 300 310 320
520 530 540 550 560 570
pF1KE1 --KPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQKYP
:: ::. .::.. : :...:::: ...:.:.:.: :
NP_066 IEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPTLTNSNYNAETYASYFSAPNS
330 340 350 360 370 380
580
pF1KE1 DGIISKPKNL
NP_066 YLTGCTEEIERLRPKSPPPKSKSDRGGGAPRGGGRGGTSAGRGRERNRSNFRGERGGFRG
390 400 410 420 430 440
>>XP_005263223 (OMIM: 616504) PREDICTED: N6-adenosine-me (314 aa)
initn: 204 init1: 114 opt: 208 Z-score: 203.7 bits: 46.7 E(85289): 0.00013
Smith-Waterman score: 213; 25.3% identity (53.5% similar) in 273 aa overlap (207-462:9-266)
180 190 200 210 220 230
pF1KE1 KRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLE----IESLLNQQ
.: : :. :... : : ..::
XP_005 MDSRLQEIRERQKLRRQLLAQQLGAESADSIGAVLN--
10 20 30
240 250 260 270 280 290
pF1KE1 STKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADR
: ::. ..: . :.: . . .:. ..:... ... .: :.: .: .
XP_005 SKDEQREIAETRETCRASYDTSAPNAK--RKYLDEGETDEDKMEEY--KDELEMQQDEE-
40 50 60 70 80 90
300 310 320 330 340
pF1KE1 PCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYV----HYEIDACMDSEAPGSKDHT
.: ... : : .. : . :: : : :.. : . : ..
XP_005 ---NLPYEEEIYKDSSTFLKGTQSLNP--HNDYCQHFVDTGHRPQNFIRDVGLADRFEEY
100 110 120 130 140
350 360 370 380 390 400
pF1KE1 PS-QELALTQSVGGDSSADRLFPPQWICCDIRYLDVSILG-KFAVVMADPPWDIHMELPY
:. .:: .. . : ::... ::. .:. : :: :.. .:: . ...
XP_005 PKLRELIRLKD---ELIAKSNTPPMYLQADIEAFDIRELTPKFDVILLEPPLEEYYRETG
150 160 170 180 190 200
410 420 430 440 450
pF1KE1 GTLTD-----DEMRRLNIP-VLQDDGFLFLWV-TGRAMELGRECLNLWGYERVDEIIWVK
: .. :.. .:.: . .:.::: .:....::: :: :::.: ..: :.:
XP_005 ITANEKCWTWDDIMKLEIDEIAAPRSFIFLWCGSGEGLDLGRVCLRKWGYRRCEDICWIK
210 220 230 240 250 260
460 470 480 490 500 510
pF1KE1 TNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYG
::.
XP_005 TNKNNPGKTKTLDPKAVFQRTKAGSQLDQRLQIATTMQKHMHPISVLLIPT
270 280 290 300 310
580 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:44:58 2016 done: Mon Nov 7 16:45:00 2016
Total Scan time: 10.800 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]