Result of FASTA (omim) for
pFN21AE5534
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5534, 437 aa
1>>>pF1KE5534 437 - 437 aa - 437 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0778+/-0.000365; mu= 18.5949+/- 0.023
mean_var=70.7303+/-13.939, 0's: 0 Z-trim(114.1): 319 B-trim: 233 in 2/50
Lambda= 0.152501
statistics sampled from 23461 (23828) to 23461 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.279), width: 16
Scan time: 7.870
The best scores are: opt bits E(85289)
NP_063947 (OMIM: 606565) transmembrane protease se ( 437) 3040 678.2 1.2e-194
NP_001167022 (OMIM: 606565) transmembrane protease ( 435) 3021 674.0 2.1e-193
XP_005271670 (OMIM: 606565) PREDICTED: transmembra ( 494) 3012 672.0 9.1e-193
XP_005271671 (OMIM: 606565) PREDICTED: transmembra ( 492) 2993 667.9 1.6e-191
NP_001077416 (OMIM: 606565) transmembrane protease ( 432) 2986 666.3 4.3e-191
XP_011541203 (OMIM: 606565) PREDICTED: transmembra ( 489) 2958 660.2 3.4e-189
NP_001277023 (OMIM: 606565) transmembrane protease ( 412) 2864 639.4 5e-183
NP_001167023 (OMIM: 606565) transmembrane protease ( 397) 2716 606.9 3.1e-173
XP_005271672 (OMIM: 606565) PREDICTED: transmembra ( 454) 2688 600.7 2.4e-171
XP_011541204 (OMIM: 606565) PREDICTED: transmembra ( 456) 2688 600.7 2.5e-171
XP_011541205 (OMIM: 606565) PREDICTED: transmembra ( 345) 2063 463.1 4.9e-130
NP_001277025 (OMIM: 606565) transmembrane protease ( 290) 2023 454.3 1.9e-127
XP_011541206 (OMIM: 606565) PREDICTED: transmembra ( 254) 1341 304.2 2.5e-82
NP_001070731 (OMIM: 610050) transmembrane protease ( 567) 900 207.4 7.6e-53
NP_001231924 (OMIM: 610050) transmembrane protease ( 563) 895 206.3 1.6e-52
NP_001193718 (OMIM: 610050) transmembrane protease ( 532) 888 204.8 4.5e-52
NP_076927 (OMIM: 605511) transmembrane protease se ( 454) 836 193.3 1.1e-48
NP_001243246 (OMIM: 605511) transmembrane protease ( 453) 835 193.1 1.3e-48
XP_011528035 (OMIM: 602060) PREDICTED: transmembra ( 384) 822 190.1 8.3e-48
NP_005647 (OMIM: 602060) transmembrane protease se ( 492) 822 190.2 1e-47
XP_011528033 (OMIM: 602060) PREDICTED: transmembra ( 492) 822 190.2 1e-47
NP_001128571 (OMIM: 602060) transmembrane protease ( 529) 822 190.2 1.1e-47
NP_002763 (OMIM: 226200,606635) enteropeptidase pr (1019) 793 184.1 1.5e-45
XP_011527961 (OMIM: 226200,606635) PREDICTED: ente (1034) 791 183.6 2e-45
XP_011527960 (OMIM: 226200,606635) PREDICTED: ente (1037) 791 183.6 2e-45
XP_011527959 (OMIM: 226200,606635) PREDICTED: ente (1049) 791 183.6 2e-45
XP_011527957 (OMIM: 226200,606635) PREDICTED: ente (1064) 791 183.7 2.1e-45
XP_011527958 (OMIM: 226200,606635) PREDICTED: ente (1064) 791 183.7 2.1e-45
XP_011527956 (OMIM: 226200,606635) PREDICTED: ente (1064) 791 183.7 2.1e-45
XP_005261100 (OMIM: 602060) PREDICTED: transmembra ( 452) 764 177.4 6.5e-44
NP_115780 (OMIM: 605511) transmembrane protease se ( 327) 757 175.8 1.5e-43
XP_005265767 (OMIM: 605369) PREDICTED: transmembra ( 301) 730 169.8 8.5e-42
NP_001275679 (OMIM: 606751) transmembrane protease ( 413) 731 170.1 9.3e-42
NP_001275680 (OMIM: 606751) transmembrane protease ( 448) 731 170.2 9.9e-42
NP_110397 (OMIM: 606751) transmembrane protease se ( 457) 731 170.2 1e-41
NP_004253 (OMIM: 605369) transmembrane protease se ( 418) 730 169.9 1.1e-41
XP_016864340 (OMIM: 605369) PREDICTED: transmembra ( 234) 725 168.6 1.5e-41
NP_001275930 (OMIM: 206200,609862) transmembrane p ( 802) 681 159.4 3.2e-38
NP_705837 (OMIM: 206200,609862) transmembrane prot ( 811) 681 159.4 3.2e-38
NP_001305325 (OMIM: 229000,612423) plasma kallikre ( 436) 667 156.1 1.7e-37
XP_016863673 (OMIM: 229000,612423) PREDICTED: plas ( 436) 667 156.1 1.7e-37
NP_000883 (OMIM: 229000,612423) plasma kallikrein ( 638) 667 156.2 2.3e-37
XP_011530232 (OMIM: 229000,612423) PREDICTED: plas ( 649) 667 156.2 2.3e-37
XP_016863670 (OMIM: 229000,612423) PREDICTED: plas ( 649) 667 156.2 2.3e-37
NP_036599 (OMIM: 609341) tryptase gamma preproprot ( 321) 654 153.1 9.6e-37
XP_011520748 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 648 151.8 2.6e-36
XP_011520749 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 648 151.8 2.6e-36
XP_011530198 (OMIM: 610399) PREDICTED: transmembra ( 345) 645 151.2 4e-36
NP_054777 (OMIM: 610399) transmembrane protease se ( 423) 645 151.2 4.7e-36
NP_892018 (OMIM: 610477) transmembrane protease se (1059) 631 148.4 8.1e-35
>>NP_063947 (OMIM: 606565) transmembrane protease serine (437 aa)
initn: 3040 init1: 3040 opt: 3040 Z-score: 3615.8 bits: 678.2 E(85289): 1.2e-194
Smith-Waterman score: 3040; 100.0% identity (100.0% similar) in 437 aa overlap (1-437:1-437)
10 20 30 40 50 60
pF1KE5 MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 GPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
370 380 390 400 410 420
430
pF1KE5 KVSAYLNWIYNVWKAEL
:::::::::::::::::
NP_063 KVSAYLNWIYNVWKAEL
430
>>NP_001167022 (OMIM: 606565) transmembrane protease ser (435 aa)
initn: 3021 init1: 3021 opt: 3021 Z-score: 3593.2 bits: 674.0 E(85289): 2.1e-193
Smith-Waterman score: 3021; 100.0% identity (100.0% similar) in 434 aa overlap (4-437:2-435)
10 20 30 40 50 60
pF1KE5 MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 GPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
360 370 380 390 400 410
430
pF1KE5 KVSAYLNWIYNVWKAEL
:::::::::::::::::
NP_001 KVSAYLNWIYNVWKAEL
420 430
>>XP_005271670 (OMIM: 606565) PREDICTED: transmembrane p (494 aa)
initn: 3012 init1: 3012 opt: 3012 Z-score: 3581.8 bits: 672.0 E(85289): 9.1e-193
Smith-Waterman score: 3012; 99.8% identity (99.8% similar) in 434 aa overlap (1-434:1-434)
10 20 30 40 50 60
pF1KE5 MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 GPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_005 GPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
370 380 390 400 410 420
430
pF1KE5 KVSAYLNWIYNVWKAEL
::::::::::::::
XP_005 KVSAYLNWIYNVWKDRTIQRSCNSPGTGLVIQQPAVPLMELRSARHTHRLTTCVCFLSFP
430 440 450 460 470 480
>>XP_005271671 (OMIM: 606565) PREDICTED: transmembrane p (492 aa)
initn: 2993 init1: 2993 opt: 2993 Z-score: 3559.2 bits: 667.9 E(85289): 1.6e-191
Smith-Waterman score: 2993; 99.8% identity (99.8% similar) in 431 aa overlap (4-434:2-432)
10 20 30 40 50 60
pF1KE5 MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 GPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_005 GPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
360 370 380 390 400 410
430
pF1KE5 KVSAYLNWIYNVWKAEL
::::::::::::::
XP_005 KVSAYLNWIYNVWKDRTIQRSCNSPGTGLVIQQPAVPLMELRSARHTHRLTTCVCFLSFP
420 430 440 450 460 470
>>NP_001077416 (OMIM: 606565) transmembrane protease ser (432 aa)
initn: 2992 init1: 2015 opt: 2986 Z-score: 3551.7 bits: 666.3 E(85289): 4.3e-191
Smith-Waterman score: 2986; 98.9% identity (98.9% similar) in 437 aa overlap (1-437:1-432)
10 20 30 40 50 60
pF1KE5 MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::
NP_001 GNWFSACFDNFTEALAETACRQMGYS-----RAVEIGPDQDLDVVEITENSQELRMRNSS
130 140 150 160 170
190 200 210 220 230 240
pF1KE5 GPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
360 370 380 390 400 410
430
pF1KE5 KVSAYLNWIYNVWKAEL
:::::::::::::::::
NP_001 KVSAYLNWIYNVWKAEL
420 430
>>XP_011541203 (OMIM: 606565) PREDICTED: transmembrane p (489 aa)
initn: 2964 init1: 1987 opt: 2958 Z-score: 3517.6 bits: 660.2 E(85289): 3.4e-189
Smith-Waterman score: 2958; 98.6% identity (98.6% similar) in 434 aa overlap (1-434:1-429)
10 20 30 40 50 60
pF1KE5 MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_011 GNWFSACFDNFTEALAETACRQMGYS-----RAVEIGPDQDLDVVEITENSQELRMRNSS
130 140 150 160 170
190 200 210 220 230 240
pF1KE5 GPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 GPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE5 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
360 370 380 390 400 410
430
pF1KE5 KVSAYLNWIYNVWKAEL
::::::::::::::
XP_011 KVSAYLNWIYNVWKDRTIQRSCNSPGTGLVIQQPAVPLMELRSARHTHRLTTCVCFLSFP
420 430 440 450 460 470
>>NP_001277023 (OMIM: 606565) transmembrane protease ser (412 aa)
initn: 2864 init1: 2864 opt: 2864 Z-score: 3406.9 bits: 639.4 E(85289): 5e-183
Smith-Waterman score: 2864; 100.0% identity (100.0% similar) in 412 aa overlap (26-437:1-412)
10 20 30 40 50 60
pF1KE5 MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
:::::::::::::::::::::::::::::::::::
NP_001 METFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
10 20 30
70 80 90 100 110 120
pF1KE5 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE5 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE5 GPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE5 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE5 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE5 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
340 350 360 370 380 390
430
pF1KE5 KVSAYLNWIYNVWKAEL
:::::::::::::::::
NP_001 KVSAYLNWIYNVWKAEL
400 410
>>NP_001167023 (OMIM: 606565) transmembrane protease ser (397 aa)
initn: 2716 init1: 2716 opt: 2716 Z-score: 3231.1 bits: 606.9 E(85289): 3.1e-173
Smith-Waterman score: 2716; 99.7% identity (100.0% similar) in 386 aa overlap (52-437:12-397)
30 40 50 60 70 80
pF1KE5 PRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKYYFLCGQPLHFIPRKQLCDGEL
:.::::::::::::::::::::::::::::
NP_001 MDPDSDQPLNSLVKVILDKYYFLCGQPLHFIPRKQLCDGEL
10 20 30 40
90 100 110 120 130 140
pF1KE5 DCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALAETACR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALAETACR
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE5 QMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLK
110 120 130 140 150 160
210 220 230 240 250 260
pF1KE5 TPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAG
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE5 SDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPA
230 240 250 260 270 280
330 340 350 360 370 380
pF1KE5 TPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVD
290 300 310 320 330 340
390 400 410 420 430
pF1KE5 TCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVWKAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVWKAEL
350 360 370 380 390
>>XP_005271672 (OMIM: 606565) PREDICTED: transmembrane p (454 aa)
initn: 2688 init1: 2688 opt: 2688 Z-score: 3197.0 bits: 600.7 E(85289): 2.4e-171
Smith-Waterman score: 2688; 99.5% identity (99.7% similar) in 383 aa overlap (52-434:12-394)
30 40 50 60 70 80
pF1KE5 PRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKYYFLCGQPLHFIPRKQLCDGEL
:.::::::::::::::::::::::::::::
XP_005 MDPDSDQPLNSLVKVILDKYYFLCGQPLHFIPRKQLCDGEL
10 20 30 40
90 100 110 120 130 140
pF1KE5 DCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALAETACR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSATGNWFSACFDNFTEALAETACR
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE5 QMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSSGPCLSGSLVSLHCLACGKSLK
110 120 130 140 150 160
210 220 230 240 250 260
pF1KE5 TPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAG
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAG
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE5 SDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPA
230 240 250 260 270 280
330 340 350 360 370 380
pF1KE5 TPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVD
290 300 310 320 330 340
390 400 410 420 430
pF1KE5 TCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVWKAEL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVWKDRTIQRS
350 360 370 380 390 400
XP_005 CNSPGTGLVIQQPAVPLMELRSARHTHRLTTCVCFLSFPALQPLSPLCPFPWD
410 420 430 440 450
>>XP_011541204 (OMIM: 606565) PREDICTED: transmembrane p (456 aa)
initn: 2688 init1: 2688 opt: 2688 Z-score: 3197.0 bits: 600.7 E(85289): 2.5e-171
Smith-Waterman score: 2694; 90.8% identity (91.0% similar) in 434 aa overlap (1-434:1-396)
10 20 30 40 50 60
pF1KE5 MLQDPDSDQPLNSLDVKPLRKPRIPMETFRKVGIPIIIALLSLASIIIVVVLIKVILDKY
:::::::::::::: .:::::::
XP_011 MLQDPDSDQPLNSL--------------------------------------VKVILDKY
10 20
70 80 90 100 110 120
pF1KE5 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFLCGQPLHFIPRKQLCDGELDCPLGEDEEHCVKSFPEGPAVAVRLSKDRSTLQVLDSAT
30 40 50 60 70 80
130 140 150 160 170 180
pF1KE5 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNWFSACFDNFTEALAETACRQMGYSSKPTFRAVEIGPDQDLDVVEITENSQELRMRNSS
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE5 GPCLSGSLVSLHCLACGKSLKTPRVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
XP_011 GPCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQVSIQYDKQHVCGGSILDPHWV
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE5 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTAAHCFRKHTDVFNWKVRAGSDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPL
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE5 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADD
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE5 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSDQWHVVGIVSWGYGCGGPSTPGVYT
330 340 350 360 370 380
430
pF1KE5 KVSAYLNWIYNVWKAEL
::::::::::::::
XP_011 KVSAYLNWIYNVWKDRTIQRSCNSPGTGLVIQQPAVPLMELRSARHTHRLTTCVCFLSFP
390 400 410 420 430 440
437 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:34:18 2016 done: Tue Nov 8 01:34:19 2016
Total Scan time: 7.870 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]