Result of FASTA (omim) for
pFN21AE1931
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1931, 445 aa
1>>>pF1KE1931 445 - 445 aa - 445 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4938+/-0.000307; mu= 17.9888+/- 0.019
mean_var=90.4152+/-18.306, 0's: 0 Z-trim(118.3): 31 B-trim: 2 in 1/53
Lambda= 0.134882
statistics sampled from 30999 (31036) to 30999 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.364), width: 16
Scan time: 8.780
The best scores are: opt bits E(85289)
NP_001091980 (OMIM: 609827) E3 ubiquitin-protein l ( 445) 3142 621.3 1.6e-177
NP_659502 (OMIM: 609827) E3 ubiquitin-protein liga ( 469) 2801 554.9 1.6e-157
XP_011543186 (OMIM: 609827) PREDICTED: E3 ubiquiti ( 469) 2801 554.9 1.6e-157
NP_001230065 (OMIM: 609827) E3 ubiquitin-protein l ( 362) 2577 511.3 1.7e-144
NP_001230064 (OMIM: 609827) E3 ubiquitin-protein l ( 406) 2550 506.0 7.1e-143
XP_016872954 (OMIM: 609827) PREDICTED: E3 ubiquiti ( 320) 2307 458.7 1e-128
NP_067078 (OMIM: 614798) E3 ubiquitin-protein liga ( 420) 2156 429.4 8.8e-120
NP_065702 (OMIM: 614797) E3 ubiquitin-protein liga ( 418) 2138 425.9 9.9e-119
XP_016860009 (OMIM: 614797) PREDICTED: E3 ubiquiti ( 418) 2138 425.9 9.9e-119
XP_011531296 (OMIM: 614797) PREDICTED: E3 ubiquiti ( 418) 2138 425.9 9.9e-119
XP_016876967 (OMIM: 614798) PREDICTED: E3 ubiquiti ( 407) 2079 414.4 2.8e-115
XP_016860010 (OMIM: 614797) PREDICTED: E3 ubiquiti ( 352) 1874 374.4 2.5e-103
XP_011531298 (OMIM: 614797) PREDICTED: E3 ubiquiti ( 320) 1716 343.7 4.3e-94
XP_005264494 (OMIM: 614797) PREDICTED: E3 ubiquiti ( 320) 1716 343.7 4.3e-94
XP_016876968 (OMIM: 614798) PREDICTED: E3 ubiquiti ( 320) 1715 343.5 4.9e-94
XP_011535294 (OMIM: 614798) PREDICTED: E3 ubiquiti ( 320) 1715 343.5 4.9e-94
XP_011535292 (OMIM: 614798) PREDICTED: E3 ubiquiti ( 320) 1715 343.5 4.9e-94
XP_006720274 (OMIM: 614798) PREDICTED: E3 ubiquiti ( 320) 1715 343.5 4.9e-94
XP_011531299 (OMIM: 614797) PREDICTED: E3 ubiquiti ( 239) 1324 267.3 3.2e-71
XP_005267947 (OMIM: 614798) PREDICTED: E3 ubiquiti ( 247) 1128 229.1 9.8e-60
>>NP_001091980 (OMIM: 609827) E3 ubiquitin-protein ligas (445 aa)
initn: 3142 init1: 3142 opt: 3142 Z-score: 3308.1 bits: 621.3 E(85289): 1.6e-177
Smith-Waterman score: 3142; 100.0% identity (100.0% similar) in 445 aa overlap (1-445:1-445)
10 20 30 40 50 60
pF1KE1 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLGYNGCLASGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLGYNGCLASGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 DSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRPPYTARIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRPPYTARIY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 AAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCGN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 VYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 ANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQEREC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQEREC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 PLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHA
370 380 390 400 410 420
430 440
pF1KE1 ACPFCGAWLTGEHGCVRLIFQGPLD
:::::::::::::::::::::::::
NP_001 ACPFCGAWLTGEHGCVRLIFQGPLD
430 440
>>NP_659502 (OMIM: 609827) E3 ubiquitin-protein ligase p (469 aa)
initn: 3128 init1: 2794 opt: 2801 Z-score: 2949.2 bits: 554.9 E(85289): 1.6e-157
Smith-Waterman score: 3084; 94.9% identity (94.9% similar) in 469 aa overlap (1-445:1-469)
10 20 30 40 50
pF1KE1 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLG---------
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLGCCEEGGEET
10 20 30 40 50 60
60 70 80 90
pF1KE1 ---------------YNGCLASGDKGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKAL
:::::::::::::::::::::::::::::::::::::::::::::
NP_659 EAQRGEVTGPRAHSCYNGCLASGDKGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKAL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 SNRGQHSISYTLSRSHSVIVEYTHDSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 SNRGQHSISYTLSRSHSVIVEYTHDSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE1 QSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 QSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE1 MHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 MHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGAT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE1 LLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 LLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYV
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE1 RCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 RCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGH
370 380 390 400 410 420
400 410 420 430 440
pF1KE1 VCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_659 VCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD
430 440 450 460
>>XP_011543186 (OMIM: 609827) PREDICTED: E3 ubiquitin-pr (469 aa)
initn: 3128 init1: 2794 opt: 2801 Z-score: 2949.2 bits: 554.9 E(85289): 1.6e-157
Smith-Waterman score: 3084; 94.9% identity (94.9% similar) in 469 aa overlap (1-445:1-469)
10 20 30 40 50
pF1KE1 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLG---------
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLGCCEEGGEET
10 20 30 40 50 60
60 70 80 90
pF1KE1 ---------------YNGCLASGDKGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKAL
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAQRGEVTGPRAHSCYNGCLASGDKGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKAL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE1 SNRGQHSISYTLSRSHSVIVEYTHDSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNRGQHSISYTLSRSHSVIVEYTHDSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE1 QSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE1 MHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGAT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE1 LLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYV
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE1 RCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGH
370 380 390 400 410 420
400 410 420 430 440
pF1KE1 VCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD
430 440 450 460
>>NP_001230065 (OMIM: 609827) E3 ubiquitin-protein ligas (362 aa)
initn: 2577 init1: 2577 opt: 2577 Z-score: 2715.1 bits: 511.3 E(85289): 1.7e-144
Smith-Waterman score: 2577; 100.0% identity (100.0% similar) in 362 aa overlap (84-445:1-362)
60 70 80 90 100 110
pF1KE1 GCLASGDKGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHS
::::::::::::::::::::::::::::::
NP_001 MHHISTPLVSKALSNRGQHSISYTLSRSHS
10 20 30
120 130 140 150 160 170
pF1KE1 VIVEYTHDSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIVEYTHDSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRP
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE1 PYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWR
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE1 EISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQ
160 170 180 190 200 210
300 310 320 330 340 350
pF1KE1 LEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRER
220 230 240 250 260 270
360 370 380 390 400 410
pF1KE1 GPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPH
280 290 300 310 320 330
420 430 440
pF1KE1 GTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD
::::::::::::::::::::::::::::::::
NP_001 GTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD
340 350 360
>>NP_001230064 (OMIM: 609827) E3 ubiquitin-protein ligas (406 aa)
initn: 2550 init1: 2550 opt: 2550 Z-score: 2686.0 bits: 506.0 E(85289): 7.1e-143
Smith-Waterman score: 2787; 91.2% identity (91.2% similar) in 445 aa overlap (1-445:1-406)
10 20 30 40 50 60
pF1KE1 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLGYNGCLASGD
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELI------------
10 20 30 40
70 80 90 100 110 120
pF1KE1 KGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTH
:::::::::::::::::::::::::::::::::
NP_001 ---------------------------STPLVSKALSNRGQHSISYTLSRSHSVIVEYTH
50 60 70 80
130 140 150 160 170 180
pF1KE1 DSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRPPYTARIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPSAQSTISRYACRILCDRRPPYTARIY
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE1 AAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCGN
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE1 VYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQE
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE1 ANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQEREC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQEREC
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE1 PLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHA
330 340 350 360 370 380
430 440
pF1KE1 ACPFCGAWLTGEHGCVRLIFQGPLD
:::::::::::::::::::::::::
NP_001 ACPFCGAWLTGEHGCVRLIFQGPLD
390 400
>>XP_016872954 (OMIM: 609827) PREDICTED: E3 ubiquitin-pr (320 aa)
initn: 2307 init1: 2307 opt: 2307 Z-score: 2431.8 bits: 458.7 E(85289): 1e-128
Smith-Waterman score: 2307; 100.0% identity (100.0% similar) in 320 aa overlap (126-445:1-320)
100 110 120 130 140 150
pF1KE1 LSNRGQHSISYTLSRSHSVIVEYTHDSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGPS
::::::::::::::::::::::::::::::
XP_016 MFQIGRSTENMIDFVVTDTSPGGGAAEGPS
10 20 30
160 170 180 190 200 210
pF1KE1 AQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVL
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE1 VMHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMHPAGGFSEDSAPGVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGA
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE1 TLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVY
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE1 VRCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRCGHVHGYHGWGCRRERGPQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCG
220 230 240 250 260 270
400 410 420 430 440
pF1KE1 HVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD
280 290 300 310 320
>>NP_067078 (OMIM: 614798) E3 ubiquitin-protein ligase p (420 aa)
initn: 1995 init1: 1037 opt: 2156 Z-score: 2271.5 bits: 429.4 E(85289): 8.8e-120
Smith-Waterman score: 2156; 71.1% identity (89.5% similar) in 419 aa overlap (30-445:3-420)
10 20 30 40 50
pF1KE1 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQ--PGEEPIKYGELIVLGYNGCLAS
:::.. . :..::.:::::.:::::: : .
NP_067 MFSPGQEEHCAPNKEPVKYGELVVLGYNGALPN
10 20 30
60 70 80 90 100 110
pF1KE1 GDKGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEY
::.:::.::.:: .: .::::::...: :::: .:::.: .:::::::::::...:.:::
NP_067 GDRGRRKSRFALYKRPKANGVKPSTVHVISTPQASKAISCKGQHSISYTLSRNQTVVVEY
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE1 THDSDTDMFQIGRSTENMIDFVVTDTSPGG-GAAEGPSAQSTISRYACRILCDRRPPYTA
:::.::::::.:::::. :::::::: :. .. :. .::::::.::::.::: ::::
NP_067 THDKDTDMFQVGRSTESPIDFVVTDTISGSQNTDEAQITQSTISRFACRIVCDRNEPYTA
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 RIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISV
::.:::::.:.::::::.::::..::: :::::::::::::: :::.:.: :::::::::
NP_067 RIFAAGFDSSKNIFLGEKAAKWKNPDGHMDGLTTNGVLVMHPRGGFTEESQPGVWREISV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE1 CGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQ
::.:::::..:::::::::::.:.:::::::::::::::::::: ::...:: :..::
NP_067 CGDVYTLRETRSAQQRGKLVESETNVLQDGSLIDLCGATLLWRTADGLFHTPTQKHIEAL
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE1 RQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQE
::: :::::::::::.:::::: : ... .:: ::.:. ::::::::.:: : . .:
NP_067 RQEINAARPQCPVGLNTLAFPSINRKEVVEEKQ-PWAYLSCGHVHGYHNWGHRSDTEANE
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE1 RECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHA
::::.:: :::::::::: :::. .: :::.:::.:::::::::.:.::.: ::::::::
NP_067 RECPMCRTVGPYVPLWLGCEAGFYVDAGPPTHAFTPCGHVCSEKSAKYWSQIPLPHGTHA
340 350 360 370 380 390
420 430 440
pF1KE1 FHAACPFCGAWLTGEHGCVRLIFQGPLD
::::::::.. :.::..:..::::::.:
NP_067 FHAACPFCATQLVGEQNCIKLIFQGPID
400 410 420
>>NP_065702 (OMIM: 614797) E3 ubiquitin-protein ligase p (418 aa)
initn: 1061 init1: 1061 opt: 2138 Z-score: 2252.6 bits: 425.9 E(85289): 9.9e-119
Smith-Waterman score: 2138; 70.5% identity (88.5% similar) in 417 aa overlap (30-445:3-418)
10 20 30 40 50 60
pF1KE1 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLGYNGCLASGD
:: .. .:.. :.:::::::::::: : .::
NP_065 MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGD
10 20 30
70 80 90 100 110 120
pF1KE1 KGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTH
.:::.::.:: .: .::::::...: :: ..::.::. ::::::::::...:.:::::
NP_065 RGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTH
40 50 60 70 80 90
130 140 150 160 170
pF1KE1 DSDTDMFQIGRSTENMIDFVVTDTSPGGGA-AEGPSAQSTISRYACRILCDRRPPYTARI
::.:::::::::::. :::::::: ::. . .. :.::::::.::::.:.: ::.::::
NP_065 DSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARI
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 YAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCG
::::::.:.::::::.::::.: :: :::::::::::::: .::.::: ::.::::::::
NP_065 YAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFTEDSKPGIWREISVCG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE1 NVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQ
::..::..::::::::.:: :.: :::::::::::::::::: :: ..::.:.::: ::
NP_065 NVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQ
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE1 EANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERE
: ::::::::::..:::::: : . . :..:::::. ::::::::.:: ..:: ..::
NP_065 EINAARPQCPVGFNTLAFPSMKR-KDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRE
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE1 CPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFH
::.:: :::::::::: :::. .: :::.:::.::::::::::. ::.: :::::::.::
NP_065 CPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFH
340 350 360 370 380 390
420 430 440
pF1KE1 AACPFCGAWLTGEHGCVRLIFQGPLD
::::::. :.::.: .:::::::::
NP_065 AACPFCAHQLAGEQGYIRLIFQGPLD
400 410
>>XP_016860009 (OMIM: 614797) PREDICTED: E3 ubiquitin-pr (418 aa)
initn: 1061 init1: 1061 opt: 2138 Z-score: 2252.6 bits: 425.9 E(85289): 9.9e-119
Smith-Waterman score: 2138; 70.5% identity (88.5% similar) in 417 aa overlap (30-445:3-418)
10 20 30 40 50 60
pF1KE1 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLGYNGCLASGD
:: .. .:.. :.:::::::::::: : .::
XP_016 MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGD
10 20 30
70 80 90 100 110 120
pF1KE1 KGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTH
.:::.::.:: .: .::::::...: :: ..::.::. ::::::::::...:.:::::
XP_016 RGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTH
40 50 60 70 80 90
130 140 150 160 170
pF1KE1 DSDTDMFQIGRSTENMIDFVVTDTSPGGGA-AEGPSAQSTISRYACRILCDRRPPYTARI
::.:::::::::::. :::::::: ::. . .. :.::::::.::::.:.: ::.::::
XP_016 DSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARI
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 YAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCG
::::::.:.::::::.::::.: :: :::::::::::::: .::.::: ::.::::::::
XP_016 YAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFTEDSKPGIWREISVCG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE1 NVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQ
::..::..::::::::.:: :.: :::::::::::::::::: :: ..::.:.::: ::
XP_016 NVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQ
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE1 EANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERE
: ::::::::::..:::::: : . . :..:::::. ::::::::.:: ..:: ..::
XP_016 EINAARPQCPVGFNTLAFPSMKR-KDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRE
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE1 CPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFH
::.:: :::::::::: :::. .: :::.:::.::::::::::. ::.: :::::::.::
XP_016 CPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFH
340 350 360 370 380 390
420 430 440
pF1KE1 AACPFCGAWLTGEHGCVRLIFQGPLD
::::::. :.::.: .:::::::::
XP_016 AACPFCAHQLAGEQGYIRLIFQGPLD
400 410
>>XP_011531296 (OMIM: 614797) PREDICTED: E3 ubiquitin-pr (418 aa)
initn: 1061 init1: 1061 opt: 2138 Z-score: 2252.6 bits: 425.9 E(85289): 9.9e-119
Smith-Waterman score: 2138; 70.5% identity (88.5% similar) in 417 aa overlap (30-445:3-418)
10 20 30 40 50 60
pF1KE1 MVLEGNPEVGSPRTSDLQHRGNKGSCVLSSPGEDAQPGEEPIKYGELIVLGYNGCLASGD
:: .. .:.. :.:::::::::::: : .::
XP_011 MFSPDQENHPSKAPVKYGELIVLGYNGSLPNGD
10 20 30
70 80 90 100 110 120
pF1KE1 KGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTH
.:::.::.:: .: .::::::...: :: ..::.::. ::::::::::...:.:::::
XP_011 RGRRKSRFALFKRPKANGVKPSTVHIACTPQAAKAISNKDQHSISYTLSRAQTVVVEYTH
40 50 60 70 80 90
130 140 150 160 170
pF1KE1 DSDTDMFQIGRSTENMIDFVVTDTSPGGGA-AEGPSAQSTISRYACRILCDRRPPYTARI
::.:::::::::::. :::::::: ::. . .. :.::::::.::::.:.: ::.::::
XP_011 DSNTDMFQIGRSTESPIDFVVTDTVPGSQSNSDTQSVQSTISRFACRIICERNPPFTARI
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 YAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAPGVWREISVCG
::::::.:.::::::.::::.: :: :::::::::::::: .::.::: ::.::::::::
XP_011 YAAGFDSSKNIFLGEKAAKWKTSDGQMDGLTTNGVLVMHPRNGFTEDSKPGIWREISVCG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE1 NVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQ
::..::..::::::::.:: :.: :::::::::::::::::: :: ..::.:.::: ::
XP_011 NVFSLRETRSAQQRGKMVEIETNQLQDGSLIDLCGATLLWRTAEGLSHTPTVKHLEALRQ
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE1 EANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERGPQERE
: ::::::::::..:::::: : . . :..:::::. ::::::::.:: ..:: ..::
XP_011 EINAARPQCPVGFNTLAFPSMKR-KDVVDEKQPWVYLNCGHVHGYHNWGNKEERDGKDRE
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE1 CPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFH
::.:: :::::::::: :::. .: :::.:::.::::::::::. ::.: :::::::.::
XP_011 CPMCRSVGPYVPLWLGCEAGFYVDAGPPTHAFSPCGHVCSEKTTAYWSQIPLPHGTHTFH
340 350 360 370 380 390
420 430 440
pF1KE1 AACPFCGAWLTGEHGCVRLIFQGPLD
::::::. :.::.: .:::::::::
XP_011 AACPFCAHQLAGEQGYIRLIFQGPLD
400 410
445 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:33:03 2016 done: Sun Nov 6 12:33:04 2016
Total Scan time: 8.780 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]