Result of FASTA (omim) for
pFN21AE1848
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1848, 365 aa
1>>>pF1KE1848 365 - 365 aa - 365 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7755+/-0.000331; mu= 15.4419+/- 0.021
mean_var=92.2533+/-18.155, 0's: 0 Z-trim(117.6): 60 B-trim: 0 in 0/51
Lambda= 0.133531
statistics sampled from 29673 (29738) to 29673 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.349), width: 16
Scan time: 8.830
The best scores are: opt bits E(85289)
NP_003386 (OMIM: 602863) protein Wnt-9a precursor ( 365) 2557 502.4 6.4e-142
XP_011542573 (OMIM: 602863) PREDICTED: protein Wnt ( 295) 2104 415.1 1e-115
NP_003387 (OMIM: 602864) protein Wnt-9b isoform 1 ( 357) 1540 306.5 6e-83
XP_011523480 (OMIM: 602864) PREDICTED: protein Wnt ( 363) 1501 299.0 1.1e-80
NP_001307387 (OMIM: 602864) protein Wnt-9b isoform ( 329) 1232 247.1 4.1e-65
NP_005421 (OMIM: 164820,615220,615221) proto-oncog ( 370) 847 173.0 9.5e-43
NP_478679 (OMIM: 601967) protein Wnt-7b precursor ( 349) 835 170.7 4.5e-42
XP_011528668 (OMIM: 601967) PREDICTED: protein Wnt ( 353) 835 170.7 4.6e-42
NP_110388 (OMIM: 158330,603490,611812) protein Wnt ( 351) 819 167.6 3.9e-41
XP_011539899 (OMIM: 158330,603490,611812) PREDICTE ( 373) 819 167.6 4e-41
NP_004616 (OMIM: 228930,276820,601570) protein Wnt ( 349) 794 162.8 1.1e-39
XP_011539900 (OMIM: 158330,603490,611812) PREDICTE ( 296) 791 162.2 1.4e-39
NP_004176 (OMIM: 601968) protein Wnt-2b isoform WN ( 372) 761 156.4 9.3e-38
NP_078613 (OMIM: 601968) protein Wnt-2b isoform WN ( 391) 761 156.5 9.7e-38
XP_011532393 (OMIM: 228930,276820,601570) PREDICTE ( 282) 752 154.6 2.5e-37
NP_003384 (OMIM: 601396) protein Wnt-8b precursor ( 351) 738 152.0 1.9e-36
NP_003382 (OMIM: 147870) protein Wnt-2 precursor [ ( 360) 738 152.0 2e-36
NP_149122 (OMIM: 606359) protein Wnt-3a precursor ( 352) 724 149.3 1.2e-35
XP_011542621 (OMIM: 606359) PREDICTED: protein Wnt ( 446) 724 149.4 1.5e-35
NP_001278809 (OMIM: 601968) protein Wnt-2b isoform ( 299) 715 147.5 3.7e-35
NP_110380 (OMIM: 165330,273395) proto-oncogene Wnt ( 355) 712 147.0 6.2e-35
NP_004617 (OMIM: 603699) protein Wnt-11 precursor ( 354) 699 144.5 3.5e-34
XP_005274288 (OMIM: 603699) PREDICTED: protein Wnt ( 354) 699 144.5 3.5e-34
NP_490645 (OMIM: 606360) protein Wnt-8a isoform 3 ( 351) 674 139.7 9.9e-33
NP_001287868 (OMIM: 606360) protein Wnt-8a isoform ( 369) 674 139.7 1e-32
XP_016865314 (OMIM: 606360) PREDICTED: protein Wnt ( 391) 674 139.7 1.1e-32
NP_001287867 (OMIM: 606360) protein Wnt-8a isoform ( 386) 665 138.0 3.5e-32
XP_016865313 (OMIM: 606360) PREDICTED: protein Wnt ( 408) 665 138.0 3.7e-32
XP_011543543 (OMIM: 603699) PREDICTED: protein Wnt ( 251) 602 125.7 1.1e-28
XP_016873730 (OMIM: 603699) PREDICTED: protein Wnt ( 251) 602 125.7 1.1e-28
XP_011543542 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 602 125.8 1.5e-28
XP_011543540 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 602 125.8 1.5e-28
XP_011543541 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 602 125.8 1.5e-28
NP_057171 (OMIM: 606267) protein Wnt-16 isoform 2 ( 355) 597 124.8 2.9e-28
NP_476509 (OMIM: 606267) protein Wnt-16 isoform 1 ( 365) 597 124.8 3e-28
XP_011541927 (OMIM: 606360) PREDICTED: protein Wnt ( 337) 575 120.6 5.3e-27
XP_011510231 (OMIM: 150400,224750,257980,606268) P ( 385) 564 118.5 2.5e-26
NP_079492 (OMIM: 150400,224750,257980,606268) prot ( 417) 564 118.5 2.7e-26
XP_011537024 (OMIM: 225300,601906,617073) PREDICTE ( 267) 557 117.0 4.9e-26
XP_016875408 (OMIM: 225300,601906,617073) PREDICTE ( 267) 557 117.0 4.9e-26
NP_003385 (OMIM: 225300,601906,617073) protein Wnt ( 389) 557 117.2 6.5e-26
XP_016865315 (OMIM: 606360) PREDICTED: protein Wnt ( 255) 540 113.7 4.6e-25
XP_016873732 (OMIM: 603699) PREDICTED: protein Wnt ( 185) 440 94.4 2.2e-19
XP_016873731 (OMIM: 603699) PREDICTED: protein Wnt ( 185) 440 94.4 2.2e-19
XP_011532388 (OMIM: 164975,180700) PREDICTED: prot ( 365) 403 87.5 5.3e-17
XP_011532391 (OMIM: 164975,180700) PREDICTED: prot ( 365) 403 87.5 5.3e-17
NP_001243034 (OMIM: 164975,180700) protein Wnt-5a ( 365) 403 87.5 5.3e-17
XP_006713387 (OMIM: 164975,180700) PREDICTED: prot ( 365) 403 87.5 5.3e-17
XP_011532390 (OMIM: 164975,180700) PREDICTED: prot ( 365) 403 87.5 5.3e-17
XP_016862617 (OMIM: 164975,180700) PREDICTED: prot ( 365) 403 87.5 5.3e-17
>>NP_003386 (OMIM: 602863) protein Wnt-9a precursor [Hom (365 aa)
initn: 2557 init1: 2557 opt: 2557 Z-score: 2668.9 bits: 502.4 E(85289): 6.4e-142
Smith-Waterman score: 2557; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KE1 MLDGSPLARWLAAAFGLTLLLAALRPSAAYFGLTGSEPLTILPLTLEPEAAAQAHYKACD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLDGSPLARWLAAAFGLTLLLAALRPSAAYFGLTGSEPLTILPLTLEPEAAAQAHYKACD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFERWNCTLEGRYRASLLKRGFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFERWNCTLEGRYRASLLKRGFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKFVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKFVK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 EFLGRRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EFLGRRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 KHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGGSDPLPRTPELVHLDDSPSFCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGGSDPLPRTPELVHLDDSPSFCL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 AGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQVRWCCYVECRQCTQREEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQVRWCCYVECRQCTQREEV
310 320 330 340 350 360
pF1KE1 YTCKG
:::::
NP_003 YTCKG
>>XP_011542573 (OMIM: 602863) PREDICTED: protein Wnt-9a (295 aa)
initn: 2104 init1: 2104 opt: 2104 Z-score: 2198.5 bits: 415.1 E(85289): 1e-115
Smith-Waterman score: 2104; 100.0% identity (100.0% similar) in 295 aa overlap (71-365:1-295)
50 60 70 80 90 100
pF1KE1 ILPLTLEPEAAAQAHYKACDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFE
::::::::::::::::::::::::::::::
XP_011 MCRRDPGVAETLVEAVSMSALECQFQFRFE
10 20 30
110 120 130 140 150 160
pF1KE1 RWNCTLEGRYRASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RWNCTLEGRYRASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENR
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE1 EAWQWGGCGDNLKYSSKFVKEFLGRRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAWQWGGCGDNLKYSSKFVKEFLGRRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE1 SGSCTVRTCWRQLAPFHEVGKHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGSCTVRTCWRQLAPFHEVGKHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGGS
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE1 DPLPRTPELVHLDDSPSFCLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPLPRTPELVHLDDSPSFCLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQ
220 230 240 250 260 270
350 360
pF1KE1 CQVRWCCYVECRQCTQREEVYTCKG
:::::::::::::::::::::::::
XP_011 CQVRWCCYVECRQCTQREEVYTCKG
280 290
>>NP_003387 (OMIM: 602864) protein Wnt-9b isoform 1 prec (357 aa)
initn: 1222 init1: 452 opt: 1540 Z-score: 1610.1 bits: 306.5 E(85289): 6e-83
Smith-Waterman score: 1540; 61.2% identity (82.9% similar) in 356 aa overlap (12-364:6-356)
10 20 30 40 50
pF1KE1 MLDGSPLARWLAAAFGLTLLLAALRPSAAYFGLTGSEPLTILPLTLEPEAAAQ--AHYKA
: :.. ::: .:.:::::: : :: .: : :: :: :
NP_003 MRPPPALALAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQ
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 CDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFERWNCTLEGRYRASLLKRG
:: ::: :.:...:::.::.:::: .:. .. :::::::: :::::.::::. .:::::
NP_003 CDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGRM--GLLKRG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 FKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKF
:::::::::.:::.:::.::.:::::::::::::..: ::.:.::::: ::::::::.::
NP_003 FKETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 VKEFLG-RRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFH
...::: .:..::::::.: ::. ::.:..:.:..::::::::::::.:::::.::.::.
NP_003 LSNFLGSKRGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 EVGKHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGGSDPLPRTPELVHLDDSPS
:.:. :: .:..:.::.:.:::: :. .: : .:. . ::. .::...::::
NP_003 ETGQVLKLRYDSAVKVSSATNEALGRLELWAPAR---QGSLTKGLAPRSGDLVYMEDSPS
240 250 260 270 280
300 310 320 330 340 350
pF1KE1 FCLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQVRWCCYVECRQCTQR
:: ...::::::: : :: .: :.:::::..::::.:. :.:::.:::::::.::.:.
NP_003 FCRPSKYSPGTAGRVCSREASCSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQE
290 300 310 320 330 340
360
pF1KE1 EEVYTCKG
: :::::
NP_003 ELVYTCKH
350
>>XP_011523480 (OMIM: 602864) PREDICTED: protein Wnt-9b (363 aa)
initn: 1201 init1: 437 opt: 1501 Z-score: 1569.4 bits: 299.0 E(85289): 1.1e-80
Smith-Waterman score: 1501; 62.4% identity (84.2% similar) in 335 aa overlap (33-364:33-362)
10 20 30 40 50 60
pF1KE1 DGSPLARWLAAAFGLTLLLAALRPSAAYFGLTGSEPLTILPLTLEPEAAAQ--AHYKACD
::: : :: .: : :: :: : ::
XP_011 GRAVSFDPLACQGLNASPGSLTSPLRRIRSLTGREVLTPFPGLGTAAAPAQGGAHLKQCD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 RLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFERWNCTLEGRYRASLLKRGFK
::: :.:...:::.::.:::: .:. .. :::::::: :::::.::::. .:::::::
XP_011 LLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGRM--GLLKRGFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKFVK
:::::::.:::.:::.::.:::::::::::::..: ::.:.::::: ::::::::.::..
XP_011 ETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLS
130 140 150 160 170 180
190 200 210 220 230
pF1KE1 EFLG-RRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEV
.::: .:..::::::.: ::. ::.:..:.:..::::::::::::.:::::.::.::.:.
XP_011 NFLGSKRGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRET
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 GKHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGGSDPLPRTPELVHLDDSPSFC
:. :: .:..:.::.:.:::: :. .: : .:. . ::. .::...::::::
XP_011 GQVLKLRYDSAVKVSSATNEALGRLELWAPAR---QGSLTKGLAPRSGDLVYMEDSPSFC
250 260 270 280 290
300 310 320 330 340 350
pF1KE1 LAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQVRWCCYVECRQCTQREE
...::::::: : :: .: :.:::::..::::.:. :.:::.:::::::.::.:.:
XP_011 RPSKYSPGTAGRVCSREASCSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQEEL
300 310 320 330 340 350
360
pF1KE1 VYTCKG
:::::
XP_011 VYTCKH
360
>>NP_001307387 (OMIM: 602864) protein Wnt-9b isoform 2 p (329 aa)
initn: 1187 init1: 452 opt: 1232 Z-score: 1290.0 bits: 247.1 E(85289): 4.1e-65
Smith-Waterman score: 1232; 60.3% identity (82.1% similar) in 302 aa overlap (12-310:6-302)
10 20 30 40 50
pF1KE1 MLDGSPLARWLAAAFGLTLLLAALRPSAAYFGLTGSEPLTILPLTLEPEAAAQ--AHYKA
: :.. ::: .:.:::::: : :: .: : :: :: :
NP_001 MRPPPALALAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQ
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 CDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFERWNCTLEGRYRASLLKRG
:: ::: :.:...:::.::.:::: .:. .. :::::::: :::::.::::. .:::::
NP_001 CDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGRM--GLLKRG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 FKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKF
:::::::::.:::.:::.::.:::::::::::::..: ::.:.::::: ::::::::.::
NP_001 FKETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 VKEFLG-RRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFH
...::: .:..::::::.: ::. ::.:..:.:..::::::::::::.:::::.::.::.
NP_001 LSNFLGSKRGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 EVGKHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGGSDPLPRTPELVHLDDSPS
:.:. :: .:..:.::.:.:::: :. .: : .:. . ::. .::...::::
NP_001 ETGQVLKLRYDSAVKVSSATNEALGRLELWAPAR---QGSLTKGLAPRSGDLVYMEDSPS
240 250 260 270 280
300 310 320 330 340 350
pF1KE1 FCLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQVRWCCYVECRQCTQR
:: ...::::::
NP_001 FCRPSKYSPGTAGWSAVARSQLITTSTSRIQAILPSQLPE
290 300 310 320
>>NP_005421 (OMIM: 164820,615220,615221) proto-oncogene (370 aa)
initn: 779 init1: 254 opt: 847 Z-score: 888.4 bits: 173.0 E(85289): 9.5e-43
Smith-Waterman score: 847; 37.0% identity (64.9% similar) in 373 aa overlap (7-363:7-369)
10 20 30 40 50
pF1KE1 MLDGSPLARWLAAAFGLTL--LLAAL--RPSAAYFGLTGSEPLTILPLTLEPEAAAQAHY
: :..:.. :.: : ::: :. ..:... : : : . :
NP_005 MGLWALLPGWVSATLLLALAALPAALAANSSGRWWGIVNVASSTNL---LTDSKSLQLVL
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 KACDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFERWNC-TLEGRYR-ASL
. .: : :::::. :..::. ... ... .. ::..::: .:::: : : . ...
NP_005 EPSLQL-LSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGPHLFGKI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 LKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKY
..:: .::::..::.:::.::..:..:: : .: :::: . :.::::.::. .
NP_005 VNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 SSKFVKEFLGR-RSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQL
. : .::. ....::: ...::: .: .. . .. :::::.:::::::::: .:
NP_005 GRLFGREFVDSGEKGRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 APFHEVGKHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGGSDPLPRTP---ELV
.. :: :. ... : .: :. :. :.. :: . : .::
NP_005 PTLRAVGDVLRDRFDGASRV------LYGNRGSNRASRAELLRLEPEDPAHKPPSPHDLV
240 250 260 270 280 290
300 310 320 330 340
pF1KE1 HLDDSPSFCL-AGRF-SPGTAGRRCHREK----NCESICCGRGHNTQSRVVTRPCQCQVR
... ::.:: .::. . ::::: :. . .:: .:::::: :... ::. :.: .
NP_005 YFEKSPNFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFH
300 310 320 330 340 350
350 360
pF1KE1 WCCYVECRQCTQREEVYTCKG
:::.: ::.::. . .. :
NP_005 WCCHVSCRNCTHTRVLHECL
360 370
>>NP_478679 (OMIM: 601967) protein Wnt-7b precursor [Hom (349 aa)
initn: 583 init1: 392 opt: 835 Z-score: 876.3 bits: 170.7 E(85289): 4.5e-42
Smith-Waterman score: 835; 39.0% identity (67.6% similar) in 318 aa overlap (59-364:38-349)
30 40 50 60 70 80
pF1KE1 AYFGLTGSEPLTILPLTLEPEAAAQAHYKACDRLK-LERKQRRMCRRDPGVAETLVEAVS
:... : .:: .:. : . .. :...
NP_478 WIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQ
10 20 30 40 50 60
90 100 110 120 130 140
pF1KE1 MSALECQFQFRFERWNCTLEGRYRA--SLLKRGFKETAFLYAISSAGLTHALAKACSAGR
:. :::.:::: ::::. :. . . :. : .:.:: :::..::..::.. ::: :
NP_478 MGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGN
70 80 90 100 110 120
150 160 170 180 190 200
pF1KE1 MERCTCD-EAPDLENR-EAWQWGGCGDNLKYSSKFVKEFL-GRRSSKDLRARVDFHNNLV
. : :: : :. :.:.::::. ...:. : ..:. .:. .:. : ...::: .
NP_478 LSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNARRLMNLHNNEA
130 140 150 160 170 180
210 220 230 240 250 260
pF1KE1 GVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETALKVGSTTNEAAG
: ::.. .. :::::::::::..::: : :.:::. ::.::..:..: :..
NP_478 GRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQV-----EVV-
190 200 210 220 230 240
270 280 290 300 310
pF1KE1 EAGAISPPRGRASGAGGSDPLPRTPELVHLDDSPSFCL--AGRFSPGTAGRRCHREK---
.:. . : : : .::... ::..: :. : :: :: :.: .
NP_478 RASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPGA
250 260 270 280 290 300
320 330 340 350 360
pF1KE1 -NCESICCGRGHNTQSRVVTRPCQCQVRWCCYVECRQCTQREEVYTCKG
.:...:::::.::.. . . :.:. .:::.:.: :..: ::.:::
NP_478 DGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
310 320 330 340
>>XP_011528668 (OMIM: 601967) PREDICTED: protein Wnt-7b (353 aa)
initn: 583 init1: 392 opt: 835 Z-score: 876.2 bits: 170.7 E(85289): 4.6e-42
Smith-Waterman score: 835; 39.0% identity (67.6% similar) in 318 aa overlap (59-364:42-353)
30 40 50 60 70 80
pF1KE1 AYFGLTGSEPLTILPLTLEPEAAAQAHYKACDRLK-LERKQRRMCRRDPGVAETLVEAVS
:... : .:: .:. : . .. :...
XP_011 SVYCPQIFLLLSSGSYLALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQ
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE1 MSALECQFQFRFERWNCTLEGRYRA--SLLKRGFKETAFLYAISSAGLTHALAKACSAGR
:. :::.:::: ::::. :. . . :. : .:.:: :::..::..::.. ::: :
XP_011 MGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGN
80 90 100 110 120 130
150 160 170 180 190 200
pF1KE1 MERCTCD-EAPDLENR-EAWQWGGCGDNLKYSSKFVKEFL-GRRSSKDLRARVDFHNNLV
. : :: : :. :.:.::::. ...:. : ..:. .:. .:. : ...::: .
XP_011 LSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVDAREIKKNARRLMNLHNNEA
140 150 160 170 180 190
210 220 230 240 250 260
pF1KE1 GVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETALKVGSTTNEAAG
: ::.. .. :::::::::::..::: : :.:::. ::.::..:..: :..
XP_011 GRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQV-----EVV-
200 210 220 230 240
270 280 290 300 310
pF1KE1 EAGAISPPRGRASGAGGSDPLPRTPELVHLDDSPSFCL--AGRFSPGTAGRRCHREK---
.:. . : : : .::... ::..: :. : :: :: :.: .
XP_011 RASRLRQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPGA
250 260 270 280 290 300
320 330 340 350 360
pF1KE1 -NCESICCGRGHNTQSRVVTRPCQCQVRWCCYVECRQCTQREEVYTCKG
.:...:::::.::.. . . :.:. .:::.:.: :..: ::.:::
XP_011 DGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
310 320 330 340 350
>>NP_110388 (OMIM: 158330,603490,611812) protein Wnt-4 p (351 aa)
initn: 712 init1: 335 opt: 819 Z-score: 859.6 bits: 167.6 E(85289): 3.9e-41
Smith-Waterman score: 819; 39.3% identity (70.3% similar) in 323 aa overlap (57-364:41-351)
30 40 50 60 70 80
pF1KE1 SAAYFGLTGSEPLTILPLTLEPEAAAQAHYKACDRLK-LERKQRRMCRRDPGVAETLVEA
..:..:: : ..: .::.:. : ... ..
NP_110 RLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRG
20 30 40 50 60 70
90 100 110 120 130 140
pF1KE1 VSMSALECQFQFRFERWNC-TLEGR-YRASLLKRGFKETAFLYAISSAGLTHALAKACSA
.... :::.::: .:::: ::.. .... .: .:.::.:::::::.. :...:::.
NP_110 AQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSS
80 90 100 110 120 130
150 160 170 180 190
pF1KE1 GRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKFVKEFLG-RRSSKDL---RARVDFHN
:..:.: ::.. . ...::.::.::. :. : . :. :. :: :: ...::
NP_110 GELEKCGCDRTVHGVSPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHN
140 150 160 170 180 190
200 210 220 230 240 250
pF1KE1 NLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETALKVGSTTNE
: .: :.: . ... :::::::::: :.:::: . ::..::. ::.:.. : .: .
NP_110 NEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEV---EPR
200 210 220 230 240
260 270 280 290 300 310
pF1KE1 AAGEAGAISPPRGRASGAGGSDPLPRTPE-LVHLDDSPSFCLAGRFSP--GTAGRRCHRE
.: . :. : .. . :.: : ::.:. ::.:: : :: :: :..
NP_110 RVGSSRALVPRNAQFK--------PHTDEDLVYLEPSPDFCEQDMRSGVLGTRGRTCNKT
250 260 270 280 290
320 330 340 350 360
pF1KE1 KN----CESICCGRG-HNTQSRVVTRPCQCQVRWCCYVECRQCTQREEVYTCKG
.. :: .::::: :..: ... : :.:. .:::.:.:::: . :..::.
NP_110 SKAIDGCELLCCGRGFHTAQVELAER-CSCKFHWCCFVKCRQCQRLVELHTCR
300 310 320 330 340 350
>>XP_011539899 (OMIM: 158330,603490,611812) PREDICTED: p (373 aa)
initn: 712 init1: 335 opt: 819 Z-score: 859.2 bits: 167.6 E(85289): 4e-41
Smith-Waterman score: 819; 39.3% identity (70.3% similar) in 323 aa overlap (57-364:63-373)
30 40 50 60 70 80
pF1KE1 SAAYFGLTGSEPLTILPLTLEPEAAAQAHYKACDRLK-LERKQRRMCRRDPGVAETLVEA
..:..:: : ..: .::.:. : ... ..
XP_011 PNQRGYEGEDTGHIPRYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRG
40 50 60 70 80 90
90 100 110 120 130 140
pF1KE1 VSMSALECQFQFRFERWNC-TLEGR-YRASLLKRGFKETAFLYAISSAGLTHALAKACSA
.... :::.::: .:::: ::.. .... .: .:.::.:::::::.. :...:::.
XP_011 AQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSS
100 110 120 130 140 150
150 160 170 180 190
pF1KE1 GRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKFVKEFLG-RRSSKDL---RARVDFHN
:..:.: ::.. . ...::.::.::. :. : . :. :. :: :: ...::
XP_011 GELEKCGCDRTVHGVSPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHN
160 170 180 190 200 210
200 210 220 230 240 250
pF1KE1 NLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETALKVGSTTNE
: .: :.: . ... :::::::::: :.:::: . ::..::. ::.:.. : .: .
XP_011 NEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEV---EPR
220 230 240 250 260
260 270 280 290 300 310
pF1KE1 AAGEAGAISPPRGRASGAGGSDPLPRTPE-LVHLDDSPSFCLAGRFSP--GTAGRRCHRE
.: . :. : .. . :.: : ::.:. ::.:: : :: :: :..
XP_011 RVGSSRALVPRNAQFK--------PHTDEDLVYLEPSPDFCEQDMRSGVLGTRGRTCNKT
270 280 290 300 310 320
320 330 340 350 360
pF1KE1 KN----CESICCGRG-HNTQSRVVTRPCQCQVRWCCYVECRQCTQREEVYTCKG
.. :: .::::: :..: ... : :.:. .:::.:.:::: . :..::.
XP_011 SKAIDGCELLCCGRGFHTAQVELAER-CSCKFHWCCFVKCRQCQRLVELHTCR
330 340 350 360 370
365 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:39:25 2016 done: Sun Nov 6 12:39:26 2016
Total Scan time: 8.830 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]