Result of FASTA (omim) for
pFN21AE5330
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5330, 269 aa
1>>>pF1KE5330 269 - 269 aa - 269 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4099+/-0.000341; mu= 14.2965+/- 0.021
mean_var=69.5885+/-14.024, 0's: 0 Z-trim(114.8): 317 B-trim: 0 in 0/54
Lambda= 0.153747
statistics sampled from 24559 (24877) to 24559 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.292), width: 16
Scan time: 6.170
The best scores are: opt bits E(85289)
NP_056933 (OMIM: 609444) chymotrypsin-like elastas ( 269) 1849 419.0 4.6e-117
NP_254275 (OMIM: 609443) chymotrypsin-like elastas ( 269) 1679 381.3 1e-105
NP_009203 (OMIM: 167800,601405) chymotrypsin-C pre ( 268) 1097 252.2 7.4e-67
NP_001962 (OMIM: 130120) chymotrypsin-like elastas ( 258) 961 222.0 8.7e-58
NP_001898 (OMIM: 118888) chymotrypsin-like proteas ( 264) 682 160.1 3.8e-39
XP_011538852 (OMIM: 167800,601405) PREDICTED: chym ( 280) 664 156.2 6.3e-38
NP_001897 (OMIM: 118890) chymotrypsinogen B isofor ( 263) 629 148.4 1.3e-35
XP_016882221 (OMIM: 142440) PREDICTED: serine prot ( 393) 587 139.2 1.2e-32
NP_892028 (OMIM: 142440) serine protease hepsin pr ( 417) 587 139.2 1.2e-32
NP_002142 (OMIM: 142440) serine protease hepsin pr ( 417) 587 139.2 1.2e-32
XP_006723244 (OMIM: 142440) PREDICTED: serine prot ( 417) 587 139.2 1.2e-32
XP_016882220 (OMIM: 142440) PREDICTED: serine prot ( 417) 587 139.2 1.2e-32
XP_005258895 (OMIM: 142440) PREDICTED: serine prot ( 417) 587 139.2 1.2e-32
NP_077078 (OMIM: 191081) tryptase beta-2 prepropro ( 275) 565 134.2 2.5e-31
NP_003285 (OMIM: 191080) tryptase alpha/beta-1 pre ( 275) 564 134.0 2.9e-31
XP_005265767 (OMIM: 605369) PREDICTED: transmembra ( 301) 561 133.3 5e-31
NP_004253 (OMIM: 605369) transmembrane protease se ( 418) 561 133.4 6.6e-31
NP_000292 (OMIM: 173350,217090) plasminogen isofor ( 810) 563 134.0 8.4e-31
XP_011528035 (OMIM: 602060) PREDICTED: transmembra ( 384) 558 132.7 9.8e-31
XP_016864340 (OMIM: 605369) PREDICTED: transmembra ( 234) 555 131.9 1e-30
XP_005261100 (OMIM: 602060) PREDICTED: transmembra ( 452) 558 132.8 1.1e-30
NP_005647 (OMIM: 602060) transmembrane protease se ( 492) 558 132.8 1.2e-30
XP_011528033 (OMIM: 602060) PREDICTED: transmembra ( 492) 558 132.8 1.2e-30
NP_001128571 (OMIM: 602060) transmembrane protease ( 529) 558 132.8 1.3e-30
NP_001243246 (OMIM: 605511) transmembrane protease ( 453) 546 130.1 7.1e-30
NP_036599 (OMIM: 609341) tryptase gamma preproprot ( 321) 543 129.4 8.5e-30
XP_011520749 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 543 129.4 9e-30
XP_011520748 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 543 129.4 9e-30
NP_001265514 (OMIM: 605236,614595) atrial natriure ( 938) 543 129.6 2.1e-29
NP_006578 (OMIM: 605236,614595) atrial natriuretic (1042) 543 129.6 2.3e-29
NP_115780 (OMIM: 605511) transmembrane protease se ( 327) 534 127.4 3.4e-29
NP_076927 (OMIM: 605511) transmembrane protease se ( 454) 534 127.4 4.5e-29
NP_001277025 (OMIM: 606565) transmembrane protease ( 290) 530 126.4 5.7e-29
NP_001305325 (OMIM: 229000,612423) plasma kallikre ( 436) 532 127.0 5.9e-29
XP_016863673 (OMIM: 229000,612423) PREDICTED: plas ( 436) 532 127.0 5.9e-29
NP_001167023 (OMIM: 606565) transmembrane protease ( 397) 530 126.5 7.5e-29
NP_001277023 (OMIM: 606565) transmembrane protease ( 412) 530 126.5 7.7e-29
NP_001077416 (OMIM: 606565) transmembrane protease ( 432) 530 126.5 8e-29
NP_001167022 (OMIM: 606565) transmembrane protease ( 435) 530 126.5 8e-29
NP_063947 (OMIM: 606565) transmembrane protease se ( 437) 530 126.5 8.1e-29
NP_000883 (OMIM: 229000,612423) plasma kallikrein ( 638) 532 127.1 8.1e-29
XP_016863670 (OMIM: 229000,612423) PREDICTED: plas ( 649) 532 127.1 8.3e-29
XP_011530232 (OMIM: 229000,612423) PREDICTED: plas ( 649) 532 127.1 8.3e-29
XP_005255530 (OMIM: 609343) PREDICTED: brain-speci ( 317) 528 126.0 8.4e-29
NP_071402 (OMIM: 609343) brain-specific serine pro ( 317) 528 126.0 8.4e-29
XP_005262880 (OMIM: 264900,612416) PREDICTED: coag ( 536) 521 124.6 3.8e-28
XP_006714200 (OMIM: 264900,612416) PREDICTED: coag ( 610) 521 124.6 4.3e-28
NP_000119 (OMIM: 264900,612416) coagulation factor ( 625) 521 124.6 4.3e-28
XP_005262878 (OMIM: 264900,612416) PREDICTED: coag ( 626) 521 124.6 4.3e-28
XP_005271672 (OMIM: 606565) PREDICTED: transmembra ( 454) 518 123.9 5.3e-28
>>NP_056933 (OMIM: 609444) chymotrypsin-like elastase fa (269 aa)
initn: 1849 init1: 1849 opt: 1849 Z-score: 2222.7 bits: 419.0 E(85289): 4.6e-117
Smith-Waterman score: 1849; 99.3% identity (99.6% similar) in 269 aa overlap (1-269:1-269)
10 20 30 40 50 60
pF1KE5 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SLIANSWVLTAAHCISSSRIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSNQVSKGN
:::::::::::::::::: ::::::::::::::::::::::::::::::::::.::::::
NP_056 SLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSV
190 200 210 220 230 240
250 260
pF1KE5 LGCNYYYKPSIFTRVSNYNDWINSVIANN
:::::::::::::::::::::::::::::
NP_056 LGCNYYYKPSIFTRVSNYNDWINSVIANN
250 260
>>NP_254275 (OMIM: 609443) chymotrypsin-like elastase fa (269 aa)
initn: 1679 init1: 1679 opt: 1679 Z-score: 2018.9 bits: 381.3 E(85289): 1e-105
Smith-Waterman score: 1679; 89.2% identity (95.5% similar) in 269 aa overlap (1-269:1-269)
10 20 30 40 50 60
pF1KE5 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG
:::::::::::::::::: :: : ..:..::::::::::::::::::::::.:::::::
NP_254 MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 SLIANSWVLTAAHCISSSRIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSNQVSKGN
::::::::::::::::::: ::: ::.::::::::::::::::::::::::::::.::::
NP_254 SLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLV
::::::::::::::::::::::::::::::::::::::::::::::::.:: :.::::::
NP_254 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSV
:::::::::.::::.:::.:::::::::: .::::::::::::::::::.:::: :. :
NP_254 VDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSR
190 200 210 220 230 240
250 260
pF1KE5 LGCNYYYKPSIFTRVSNYNDWINSVIANN
::::::.:::.::::::: ::::::::::
NP_254 LGCNYYHKPSVFTRVSNYIDWINSVIANN
250 260
>>NP_009203 (OMIM: 167800,601405) chymotrypsin-C preprop (268 aa)
initn: 1076 init1: 664 opt: 1097 Z-score: 1321.2 bits: 252.2 E(85289): 7.4e-67
Smith-Waterman score: 1097; 59.6% identity (77.0% similar) in 265 aa overlap (1-263:1-263)
10 20 30 40 50
pF1KE5 MIRTLLLSTLVAGALSCGVSTYAPDMS-RMLGGEEARPNSWPWQVSLQYSSNGQWYHTCG
:. .:..:.: : :::: .. :..: :..:::.:::.:::::.:::: .: : ::::
NP_009 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 GSLIANSWVLTAAHCISSSRIYRVMLGQHNLYVA-ESGSLAVSVSKIVVHKDWNSNQVSK
:.:::...:::::::::..: ::: .:..:: : : ::: :.:. : ::: ::. .
NP_009 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLR-
70 80 90 100 110
120 130 140 150 160 170
pF1KE5 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRL
:::::.:::. : :.: ::.:::: ..::..::::::::::: ::: . : :.::
NP_009 -NDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 LVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLT
:::.:::: ::: :: .:.:::::::: .:::::::::::: .: ::: :: :.
NP_009 PVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFG
180 190 200 210 220 230
240 250 260
pF1KE5 SVLGCNYYYKPSIFTRVSNYNDWINSVIANN
: ::: :: ..:::: : ::::
NP_009 SRRGCNTRKKPVVYTRVSAYIDWINEKMQL
240 250 260
>>NP_001962 (OMIM: 130120) chymotrypsin-like elastase fa (258 aa)
initn: 937 init1: 795 opt: 961 Z-score: 1158.5 bits: 222.0 E(85289): 8.7e-58
Smith-Waterman score: 961; 56.0% identity (79.4% similar) in 243 aa overlap (27-269:17-258)
10 20 30 40 50 60
pF1KE5 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG
.:..:: :: :::: :.:::: :.:. ::::::
NP_001 MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGG
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 SLIANSWVLTAAHCISSSRIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSNQVSKGN
.:: ..::.:::::.. .. .::. :.::: .. :::.::::: :::..:. :
NP_001 TLIRQNWVMTAAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLV
:::::.::. :.:.. .::. :: :.:: :: :::.::::. .::: : . :.:. :
NP_001 DIALLRLAQSVTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE5 VDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSV
:::: ::::..::::::..:.::::::: :.:::::::.: . .:.. :::. :..:
NP_001 VDYAICSSSSYWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLV-NGKYSVHGVTSFVSS
180 190 200 210 220
250 260
pF1KE5 LGCNYYYKPSIFTRVSNYNDWINSVIANN
::: ::..::.:: : .:::.:::.:
NP_001 RGCNVSRKPTVFTQVSAYISWINNVIASN
230 240 250
>>NP_001898 (OMIM: 118888) chymotrypsin-like protease CT (264 aa)
initn: 502 init1: 179 opt: 682 Z-score: 823.9 bits: 160.1 E(85289): 3.8e-39
Smith-Waterman score: 682; 41.6% identity (67.5% similar) in 274 aa overlap (1-269:2-264)
10 20 30 40 50
pF1KE5 MIRTLLLSTLVAGA-LSCGVSTYAPDMS---RMLGGEEARPNSWPWQVSLQYSSNGQWY
.. .: :: .. :. .::. . : .: :...::.: .::::::::: ::. .
NP_001 MLLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSG---F
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 HTCGGSLIANSWVLTAAHCISSSRIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSNQ
: ::::::..:::.::::: : . :.::... ..:::. ..: .:::.
NP_001 HFCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 VSKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAL-PDDLK
.. ::..:::::.:.. : .:. .:: .. : .. : .::::::. : . : :.
NP_001 MN--NDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 QGRLLVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGI
: : .: : . .:::.. .:::::: :. .:.::::::: :: .. : . ::
NP_001 QVALPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGN-TWVLIGI
180 190 200 210 220 230
240 250 260
pF1KE5 GSLTSVLGCNYYYKPSIFTRVSNYNDWINSVIANN
: . .:: :...::::... :::.::: :
NP_001 VSWGTK-NCNVR-APAVYTRVSKFSTWINQVIAYN
240 250 260
>>XP_011538852 (OMIM: 167800,601405) PREDICTED: chymotry (280 aa)
initn: 622 init1: 322 opt: 664 Z-score: 801.9 bits: 156.2 E(85289): 6.3e-38
Smith-Waterman score: 664; 55.5% identity (76.9% similar) in 182 aa overlap (1-179:1-180)
10 20 30 40 50
pF1KE5 MIRTLLLSTLVAGALSCGVSTYAPDMS-RMLGGEEARPNSWPWQVSLQYSSNGQWYHTCG
:. .:..:.: : :::: .. :..: :..:::.:::.:::::.:::: .: : ::::
XP_011 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 GSLIANSWVLTAAHCISSSRIYRVMLGQHNLYVA-ESGSLAVSVSKIVVHKDWNSNQVSK
:.:::...:::::::::..: ::: .:..:: : : ::: :.:. : ::: ::. .
XP_011 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLR-
70 80 90 100 110
120 130 140 150 160 170
pF1KE5 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQG-R
:::::.:::. : :.: ::.:::: ..::..::::::::::: . : .: : :
XP_011 -NDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWRGLRWPTELPVGER
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 LLVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSL
.:
XP_011 FLGGVWHRQLWLPAGLQHPQEAGSLHPGVRLHRLDQRENAAVICCWERRQRVPATAINFL
180 190 200 210 220 230
>>NP_001897 (OMIM: 118890) chymotrypsinogen B isoform 1 (263 aa)
initn: 353 init1: 149 opt: 629 Z-score: 760.4 bits: 148.4 E(85289): 1.3e-35
Smith-Waterman score: 629; 39.1% identity (67.8% similar) in 276 aa overlap (1-269:1-263)
10 20 30 40 50
pF1KE5 MIRTLLLS--TLVAGALSCGVSTYAP---DMSRMLGGEEARPNSWPWQVSLQYSSNGQWY
: ::: .::..:..::: . : .::...::.: :.::::::::: ... .
NP_001 MASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTG---F
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 HTCGGSLIANSWVLTAAHC-ISSSRIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSN
: ::::::...::.::::: . .: . :. :. . : . .....: : :. . .
NP_001 HFCGGSLISEDWVVTAAHCGVRTSDV--VVAGEFDQGSDEENIQVLKIAK--VFKNPKFS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 QVSKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGA-LPDDL
.. .:::.:::::.:. ... .. .::: : .: . : .::::. . :. :: :
NP_001 ILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE5 KQGRLLVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHG
.:. : ... : :..: :: . :::::..:: .: ::::::: :: .:: : . :
NP_001 QQAALPLLSNAECKKS--WGRRITDVMICAGASGV-SSCMGDSGGPLVCQ-KDGAWTLVG
180 190 200 210 220
240 250 260
pF1KE5 IGSLTSVLGCNYYYKPSIFTRVSNYNDWINSVIANN
: : : :. .:....::.. :.....: :
NP_001 IVSWGSDT-CSTS-SPGVYARVTKLIPWVQKILAAN
230 240 250 260
>>XP_016882221 (OMIM: 142440) PREDICTED: serine protease (393 aa)
initn: 589 init1: 243 opt: 587 Z-score: 707.4 bits: 139.2 E(85289): 1.2e-32
Smith-Waterman score: 587; 38.0% identity (64.6% similar) in 271 aa overlap (10-266:118-376)
10 20 30
pF1KE5 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNS
:.: .:: : :..::... .
XP_016 GFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVD--RIVGGRDTSLGR
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE5 WPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISS-SRI---YRVMLGQHNLYVAES
:::::::.:.. : :::::....::::::::. .:. .::. : . :
XP_016 WPWQVSLRYDGA----HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA--VAQASP
150 160 170 180 190
100 110 120 130 140
pF1KE5 GSLAVSVSKIVVH------KDWNSNQVSKGNDIALLKLANPVSLTDKIQLACLPPAGTIL
.: ..:. .: : .: ::.. : :::::..:..:. ::. :: .::: :: :
XP_016 HGLQLGVQAVVYHGGYLPFRDPNSEENS--NDIALVHLSSPLPLTEYIQPVCLPAAGQAL
200 210 220 230 240 250
150 160 170 180 190 200
pF1KE5 PNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGWWGSTVKTNMICAG-GDGV
.. : ::::: : : :...:. ... .:... ..:. .: .:.::: .:
XP_016 VDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGG
260 270 280 290 300 310
210 220 230 240 250 260
pF1KE5 ICTCNGDSGGPLNCQAS---DGRWEVHGIGSLTSVLGCNYYYKPSIFTRVSNYNDWINSV
: .:.::::::. :. : ::.. :: : . :: ::...:.::.. .:: ..
XP_016 IDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT--GCALAQKPGVYTKVSDFREWIFQA
320 330 340 350 360 370
pF1KE5 IANN
:
XP_016 IKVKVGSRWEPGWGRLGV
380 390
>>NP_892028 (OMIM: 142440) serine protease hepsin precur (417 aa)
initn: 589 init1: 243 opt: 587 Z-score: 707.0 bits: 139.2 E(85289): 1.2e-32
Smith-Waterman score: 587; 38.0% identity (64.6% similar) in 271 aa overlap (10-266:146-404)
10 20 30
pF1KE5 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNS
:.: .:: : :..::... .
NP_892 GFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVD--RIVGGRDTSLGR
120 130 140 150 160 170
40 50 60 70 80 90
pF1KE5 WPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISS-SRI---YRVMLGQHNLYVAES
:::::::.:.. : :::::....::::::::. .:. .::. : . :
NP_892 WPWQVSLRYDGA----HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA--VAQASP
180 190 200 210 220
100 110 120 130 140
pF1KE5 GSLAVSVSKIVVH------KDWNSNQVSKGNDIALLKLANPVSLTDKIQLACLPPAGTIL
.: ..:. .: : .: ::.. : :::::..:..:. ::. :: .::: :: :
NP_892 HGLQLGVQAVVYHGGYLPFRDPNSEENS--NDIALVHLSSPLPLTEYIQPVCLPAAGQAL
230 240 250 260 270 280
150 160 170 180 190 200
pF1KE5 PNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGWWGSTVKTNMICAG-GDGV
.. : ::::: : : :...:. ... .:... ..:. .: .:.::: .:
NP_892 VDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGG
290 300 310 320 330 340
210 220 230 240 250 260
pF1KE5 ICTCNGDSGGPLNCQAS---DGRWEVHGIGSLTSVLGCNYYYKPSIFTRVSNYNDWINSV
: .:.::::::. :. : ::.. :: : . :: ::...:.::.. .:: ..
NP_892 IDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT--GCALAQKPGVYTKVSDFREWIFQA
350 360 370 380 390 400
pF1KE5 IANN
:
NP_892 IKTHSEASGMVTQL
410
>>NP_002142 (OMIM: 142440) serine protease hepsin precur (417 aa)
initn: 589 init1: 243 opt: 587 Z-score: 707.0 bits: 139.2 E(85289): 1.2e-32
Smith-Waterman score: 587; 38.0% identity (64.6% similar) in 271 aa overlap (10-266:146-404)
10 20 30
pF1KE5 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNS
:.: .:: : :..::... .
NP_002 GFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVD--RIVGGRDTSLGR
120 130 140 150 160 170
40 50 60 70 80 90
pF1KE5 WPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISS-SRI---YRVMLGQHNLYVAES
:::::::.:.. : :::::....::::::::. .:. .::. : . :
NP_002 WPWQVSLRYDGA----HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA--VAQASP
180 190 200 210 220
100 110 120 130 140
pF1KE5 GSLAVSVSKIVVH------KDWNSNQVSKGNDIALLKLANPVSLTDKIQLACLPPAGTIL
.: ..:. .: : .: ::.. : :::::..:..:. ::. :: .::: :: :
NP_002 HGLQLGVQAVVYHGGYLPFRDPNSEENS--NDIALVHLSSPLPLTEYIQPVCLPAAGQAL
230 240 250 260 270 280
150 160 170 180 190 200
pF1KE5 PNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGWWGSTVKTNMICAG-GDGV
.. : ::::: : : :...:. ... .:... ..:. .: .:.::: .:
NP_002 VDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGG
290 300 310 320 330 340
210 220 230 240 250 260
pF1KE5 ICTCNGDSGGPLNCQAS---DGRWEVHGIGSLTSVLGCNYYYKPSIFTRVSNYNDWINSV
: .:.::::::. :. : ::.. :: : . :: ::...:.::.. .:: ..
NP_002 IDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT--GCALAQKPGVYTKVSDFREWIFQA
350 360 370 380 390 400
pF1KE5 IANN
:
NP_002 IKTHSEASGMVTQL
410
269 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:50:12 2016 done: Mon Nov 7 23:50:13 2016
Total Scan time: 6.170 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]