Result of FASTA (ccds) for
pFN21AE6372
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6372, 357 aa
1>>>pF1KE6372 357 - 357 aa - 357 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1484+/-0.000996; mu= 4.4449+/- 0.060
mean_var=201.0175+/-38.818, 0's: 0 Z-trim(111.6): 33 B-trim: 0 in 0/53
Lambda= 0.090460
statistics sampled from 12486 (12504) to 12486 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.384), width: 16
Scan time: 2.480
The best scores are: opt bits E(32554)
CCDS48158.1 ATP1B4 gene_id:23439|Hs108|chrX ( 357) 2441 330.9 1e-90
CCDS14598.1 ATP1B4 gene_id:23439|Hs108|chrX ( 353) 2391 324.4 9.2e-89
CCDS32550.1 ATP1B2 gene_id:482|Hs108|chr17 ( 290) 814 118.5 7.2e-27
CCDS9539.1 ATP4B gene_id:496|Hs108|chr13 ( 291) 679 100.9 1.5e-21
CCDS3121.1 ATP1B3 gene_id:483|Hs108|chr3 ( 279) 673 100.1 2.4e-21
CCDS1276.1 ATP1B1 gene_id:481|Hs108|chr1 ( 303) 476 74.4 1.4e-13
>>CCDS48158.1 ATP1B4 gene_id:23439|Hs108|chrX (357 aa)
initn: 2441 init1: 2441 opt: 2441 Z-score: 1742.2 bits: 330.9 E(32554): 1e-90
Smith-Waterman score: 2441; 100.0% identity (100.0% similar) in 357 aa overlap (1-357:1-357)
10 20 30 40 50 60
pF1KE6 MRRQLRSRRAPSFPYSYRYRLDDPDEANQNYLADEEEEAEEEARVTVVPKSEEEEEEEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 MRRQLRSRRAPSFPYSYRYRLDDPDEANQNYLADEEEEAEEEARVTVVPKSEEEEEEEEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLILLIYFFFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 EEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLILLIYFFFY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHSLNFNFNVSEPDTWQHYVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 ASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHSLNFNFNVSEPDTWQHYVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SLNGFLQGYNDSLQEEMNVDCPPGQYFIQDGNEDEDKKACQFKRSFLKNCSGLEDPTFGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 SLNGFLQGYNDSLQEEMNVDCPPGQYFIQDGNEDEDKKACQFKRSFLKNCSGLEDPTFGY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 STGQPCILLKMNRIVGFRPELGDPVKVSCKVQRGDENDIRSISYYPESASFDLRYYPYYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 STGQPCILLKMNRIVGFRPELGDPVKVSCKVQRGDENDIRSISYYPESASFDLRYYPYYG
250 260 270 280 290 300
310 320 330 340 350
pF1KE6 KLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNIET
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 KLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNIET
310 320 330 340 350
>>CCDS14598.1 ATP1B4 gene_id:23439|Hs108|chrX (353 aa)
initn: 1732 init1: 1732 opt: 2391 Z-score: 1707.0 bits: 324.4 E(32554): 9.2e-89
Smith-Waterman score: 2391; 98.9% identity (98.9% similar) in 357 aa overlap (1-357:1-353)
10 20 30 40 50 60
pF1KE6 MRRQLRSRRAPSFPYSYRYRLDDPDEANQNYLADEEEEAEEEARVTVVPKSEEEEEEEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MRRQLRSRRAPSFPYSYRYRLDDPDEANQNYLADEEEEAEEEARVTVVPKSEEEEEEEEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLILLIYFFFY
:::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
CCDS14 EEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTG----LILLIYFFFY
70 80 90 100 110
130 140 150 160 170 180
pF1KE6 ASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHSLNFNFNVSEPDTWQHYVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHSLNFNFNVSEPDTWQHYVI
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 SLNGFLQGYNDSLQEEMNVDCPPGQYFIQDGNEDEDKKACQFKRSFLKNCSGLEDPTFGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 SLNGFLQGYNDSLQEEMNVDCPPGQYFIQDGNEDEDKKACQFKRSFLKNCSGLEDPTFGY
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 STGQPCILLKMNRIVGFRPELGDPVKVSCKVQRGDENDIRSISYYPESASFDLRYYPYYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 STGQPCILLKMNRIVGFRPELGDPVKVSCKVQRGDENDIRSISYYPESASFDLRYYPYYG
240 250 260 270 280 290
310 320 330 340 350
pF1KE6 KLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNIET
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 KLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNIET
300 310 320 330 340 350
>>CCDS32550.1 ATP1B2 gene_id:482|Hs108|chr17 (290 aa)
initn: 720 init1: 338 opt: 814 Z-score: 595.9 bits: 118.5 E(32554): 7.2e-27
Smith-Waterman score: 814; 42.0% identity (75.0% similar) in 276 aa overlap (84-355:12-287)
60 70 80 90 100 110
pF1KE6 EEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLIL
: .. .:..:.:. ..:..::: ::..::
CCDS32 MVIQKEKKSCGQVVEEWKEFVWNPRTHQFMGRTGTSWAFIL
10 20 30 40
120 130 140 150 160 170
pF1KE6 LIYFFFYASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHSLNFNFNVSEPD
:.:. ::. :.:..:: :.... :.: . : . .:. ::.:::: ...:. :::. .
CCDS32 LFYLVFYGFLTAMFTLTMWVMLQTVSDHTPKYQDRLATPGLMIRPKTENLDVIVNVSDTE
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE6 TWQHYVISLNGFLQGYNDSLQEEMNVDCPPGQYFIQ--DGNEDEDKKACQFKRSFLKNCS
.:...: .:: ::. ::::.: . : : ::.:. : .: . :.::::.:. : :::
CCDS32 SWDQHVQKLNKFLEPYNDSIQAQKNDVCRPGRYYEQPDNGVLNYPKRACQFNRTQLGNCS
110 120 130 140 150 160
240 250 260 270 280
pF1KE6 GLEDPT-FGYSTGQPCILLKMNRIVGFRPELGDPVKVSCKVQRG-DENDIRSISYYPESA
:. : : .::::::::...::::...: .. ..:.: .: : ... .. ..: ..
CCDS32 GIGDSTHYGYSTGQPCVFIKMNRVINFYAGANQSMNVTCAGKRDEDAENLGNFVMFPANG
170 180 190 200 210 220
290 300 310 320 330 340
pF1KE6 SFDLRYYPYYGKLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFVGRV
..:: :.::::: :::::.::::..: .:. : : :.:.... .. .: :.:.:::
CCDS32 NIDLMYFPYYGKKFHVNYTQPLVAVKFLNVTPNVEVNVECRINAANIATDDERDKFAGRV
230 240 250 260 270 280
350
pF1KE6 IFTLNIET
: : :
CCDS32 AFKLRINKT
290
>>CCDS9539.1 ATP4B gene_id:496|Hs108|chr13 (291 aa)
initn: 602 init1: 210 opt: 679 Z-score: 500.6 bits: 100.9 E(32554): 1.5e-21
Smith-Waterman score: 679; 35.4% identity (70.4% similar) in 280 aa overlap (84-356:12-290)
60 70 80 90 100 110
pF1KE6 EEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLIL
:... ...: :.:. ..:.:: . : :
CCDS95 MAALQEKKTCGQRMEEFQRYCWNPDTGQMLGRTLSRWVWIS
10 20 30 40
120 130 140 150 160 170
pF1KE6 LIYFFFYASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHS---LNFNFNVS
: : ::. ......::.:.:. :..:: : . .... ::: .:: ... :.. .:::
CCDS95 LYYVAFYVVMTGLFALCLYVLMQTVDPYTPDYQDQLRSPGVTLRPDVYGEKGLEIVYNVS
50 60 70 80 90 100
180 190 200 210 220
pF1KE6 EPDTWQHYVISLNGFLQGYNDSLQEEMNVDCPPGQYFIQDG--NEDEDKKACQFKRSFLK
. :: . .:..:: ::. . ::. ...: :::.:.. .. : .:.: ..:.
CCDS95 DNRTWADLTQTLHAFLAGYSPAAQED-SINCTSEQYFFQESFRAPNHTKFSCKFTADMLQ
110 120 130 140 150 160
230 240 250 260 270 280
pF1KE6 NCSGLEDPTFGYSTGQPCILLKMNRIVGFRPELGDPVKVSCKV--QRGDENDIRSISYYP
::::: ::.::. :.::...:::::: : : :. .:.: : . .. ...:::
CCDS95 NCSGLADPNFGFEEGKPCFIIKMNRIVKFLPSNGSAPRVDCAFLDQPRELGQPLQVKYYP
170 180 190 200 210 220
290 300 310 320 330 340
pF1KE6 ESASFDLRYYPYYGKLTHVNYTSPLVAMHFTDVVKNQAVPVQCQLKGKGVINDVINDRFV
...:.:.:.::::: .. .:..:::: .. .. .: : . :.. .. : . .: .
CCDS95 PNGTFSLHYFPYYGKKAQPHYSNPLVAAKLLNIPRNAEVAIVCKVMAEHVTFNNPHDPYE
230 240 250 260 270 280
350
pF1KE6 GRVIFTLNIET
:.: : :.::
CCDS95 GKVEFKLKIEK
290
>>CCDS3121.1 ATP1B3 gene_id:483|Hs108|chr3 (279 aa)
initn: 518 init1: 220 opt: 673 Z-score: 496.6 bits: 100.1 E(32554): 2.4e-21
Smith-Waterman score: 673; 38.5% identity (72.4% similar) in 275 aa overlap (84-353:11-275)
60 70 80 90 100 110
pF1KE6 EEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFLARTGQSWSLIL
:.: . ....: ::.::..::.:::
CCDS31 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLIL
10 20 30 40
120 130 140 150 160 170
pF1KE6 LIYFFFYASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPF-AHSLNFNFNVSEP
:.:. ::. :::.... :.... :.. .: . ... ::.:. : . .:...:. :.:
CCDS31 LFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDP
50 60 70 80 90 100
180 190 200 210 220 230
pF1KE6 DTWQHYVISLNGFLQGYNDSLQEEMNVD-CPPGQYFIQDGNEDEDKKACQFKRSFLKNCS
.. :. .:. ::. : .:.:. :. :: : : : : :::: :.:. ::
CCDS31 TSYAGYIEDLKKFLKPY--TLEEQKNLTVCPDGALFEQKGPV---YVACQFPISLLQACS
110 120 130 140 150
240 250 260 270 280 290
pF1KE6 GLEDPTFGYSTGQPCILLKMNRIVGFRPELGDPVKVSCKVQRGDENDIRSISYYPESASF
:..:: :::: :.::::.:::::.:..:: : : ...: :.... :: ... ::... .
CCDS31 GMNDPDFGYSQGNPCILVKMNRIIGLKPE-GVP-RIDC-VSKNE--DIPNVAVYPHNGMI
160 170 180 190 200 210
300 310 320 330 340
pF1KE6 DLRYYPYYGKLTHVNYTSPLVAMHFTDVVKN--QAVPVQCQLKGKGVINDVIN-DRFVGR
::.:.::::: ::.: .::::.. . . .: . : :.:.. :.. ... . :.:.::
CCDS31 DLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGR
220 230 240 250 260 270
350
pF1KE6 VIFTLNIET
:.: .
CCDS31 VMFKITARA
>>CCDS1276.1 ATP1B1 gene_id:481|Hs108|chr1 (303 aa)
initn: 635 init1: 279 opt: 476 Z-score: 357.2 bits: 74.4 E(32554): 1.4e-13
Smith-Waterman score: 625; 34.7% identity (65.3% similar) in 308 aa overlap (73-356:4-300)
50 60 70 80 90 100
pF1KE6 ARVTVVPKSEEEEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSEYLWDPERRMFL
:... :. :.: ..:. :.. ::
CCDS12 MARGKAKEEGS--WKK------FIWNSEKKEFL
10 20
110 120 130 140 150 160
pF1KE6 ARTGQSWSLILLIYFFFYASLAAVITLCMYTLFLTISPYIPTFTERVKPPGVMIRPFAHS
.::: :: :::.: .::. ::... . ...:::: . ::. .:: :::. : ..
CCDS12 GRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQIPQIQK
30 40 50 60 70 80
170 180 190 200 210
pF1KE6 LNFNFNVSEPDTWQHYVISLNGFLQGYNDSLQEEMNV--DC---PPGQYFIQDGNEDE-D
...: ..: ... ::... ::. :.:: :.. . :: : : :... .
CCDS12 TEISFRPNDPKSYEAYVLNIVRFLEKYKDSAQRDDMIFEDCGDVPSEPKERGDFNHERGE
90 100 110 120 130 140
220 230 240 250 260
pF1KE6 KKACQFKRSFLKNCSGLEDPTFGYSTGQPCILLKMNRIVGFRPELGD-------PV----
.:.:.:: .: :::::.: :.::. :.:::..:.::..::.:. ::
CCDS12 RKVCRFKLEWLGNCSGLNDETYGYKEGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYN
150 160 170 180 190 200
270 280 290 300 310
pF1KE6 ----KVSCKVQRGDEND-IRSISYYP--ESASFDLRYYPYYGKLTHVNYTSPLVAMHFTD
:.: .: ...: . .. :. .: .: :.:::::::: . .: .::.:..::.
CCDS12 PNVLPVQCTGKRDEDKDKVGNVEYFGLGNSPGFPLQYYPYYGKLLQPKYLQPLLAVQFTN
210 220 230 240 250 260
320 330 340 350
pF1KE6 VVKNQAVPVQCQLKGKGVINDVINDRFVGRVIFTLNIET
.. . . ..:. :.. :. .::: :: : ..::
CCDS12 LTMDTEIRIECKAYGEN-IGYSEKDRFQGR--FDVKIEVKS
270 280 290 300
357 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:40:59 2016 done: Tue Nov 8 12:41:00 2016
Total Scan time: 2.480 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]