Result of FASTA (omim) for
pFN21AE3187
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3187, 428 aa
1>>>pF1KE3187 428 - 428 aa - 428 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6527+/-0.000337; mu= 16.1778+/- 0.021
mean_var=98.8855+/-20.539, 0's: 0 Z-trim(116.9): 185 B-trim: 1586 in 3/50
Lambda= 0.128976
statistics sampled from 28187 (28454) to 28187 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.334), width: 16
Scan time: 9.430
The best scores are: opt bits E(85289)
NP_919445 (OMIM: 300439) E3 ubiquitin-protein liga ( 428) 2913 552.5 7.3e-157
NP_078815 (OMIM: 300439) E3 ubiquitin-protein liga ( 402) 1910 365.9 1.1e-100
NP_060233 (OMIM: 612482,617108) E3 ubiquitin-prote ( 783) 329 72.0 6.2e-12
NP_001292473 (OMIM: 612482,617108) E3 ubiquitin-pr ( 783) 329 72.0 6.2e-12
XP_011523257 (OMIM: 612482,617108) PREDICTED: E3 u ( 869) 329 72.0 6.7e-12
XP_016880289 (OMIM: 612482,617108) PREDICTED: E3 u ( 869) 329 72.0 6.7e-12
NP_001292474 (OMIM: 612482,617108) E3 ubiquitin-pr ( 656) 298 66.1 3e-10
XP_011523258 (OMIM: 612482,617108) PREDICTED: E3 u ( 742) 298 66.2 3.2e-10
NP_001193927 (OMIM: 612062) E3 ubiquitin-protein l ( 936) 280 62.9 3.9e-09
NP_115549 (OMIM: 612062) E3 ubiquitin-protein liga ( 836) 263 59.7 3.2e-08
XP_011528737 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 263 59.7 3.2e-08
XP_011528740 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 263 59.7 3.2e-08
XP_011528739 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 263 59.7 3.2e-08
XP_011528738 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 263 59.7 3.2e-08
XP_016884479 (OMIM: 612062) PREDICTED: E3 ubiquiti ( 841) 263 59.7 3.2e-08
XP_016861150 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 193) 242 55.2 1.7e-07
XP_016861149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 250) 242 55.3 2e-07
XP_016861148 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 242 55.4 2.1e-07
XP_016861146 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 242 55.4 2.1e-07
XP_016861147 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 242 55.4 2.1e-07
XP_005247149 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 242 55.4 2.1e-07
XP_016861145 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 242 55.4 2.1e-07
XP_011510678 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 262) 242 55.4 2.1e-07
NP_001307293 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 241 55.2 2.7e-07
NP_001307291 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 241 55.2 2.7e-07
NP_001307292 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 241 55.2 2.7e-07
NP_001307294 (OMIM: 610431) E3 ubiquitin-protein l ( 315) 241 55.2 2.7e-07
XP_011510675 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 242 55.5 2.7e-07
XP_016861144 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 242 55.5 2.7e-07
XP_016861143 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 242 55.5 2.7e-07
NP_899237 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 242 55.5 2.7e-07
NP_009213 (OMIM: 609247) E3 ubiquitin-protein liga ( 381) 242 55.5 2.7e-07
XP_011510676 (OMIM: 609247) PREDICTED: E3 ubiquiti ( 381) 242 55.5 2.7e-07
NP_001307290 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 241 55.3 2.9e-07
NP_001307286 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 241 55.3 2.9e-07
NP_001307288 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 241 55.3 2.9e-07
NP_056343 (OMIM: 610431) E3 ubiquitin-protein liga ( 350) 241 55.3 2.9e-07
XP_016879916 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 350) 241 55.3 2.9e-07
NP_001307289 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 241 55.3 2.9e-07
NP_001307285 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 241 55.3 2.9e-07
NP_001307287 (OMIM: 610431) E3 ubiquitin-protein l ( 350) 241 55.3 2.9e-07
XP_016879917 (OMIM: 610431) PREDICTED: E3 ubiquiti ( 227) 219 51.0 3.6e-06
XP_005259651 (OMIM: 615177) PREDICTED: E3 ubiquiti ( 284) 195 46.6 9.5e-05
NP_009150 (OMIM: 612489) RING finger protein 24 is ( 148) 191 45.6 9.8e-05
NP_001308678 (OMIM: 612489) RING finger protein 24 ( 148) 191 45.6 9.8e-05
NP_001127809 (OMIM: 612489) RING finger protein 24 ( 148) 191 45.6 9.8e-05
NP_919442 (OMIM: 615177) E3 ubiquitin-protein liga ( 311) 195 46.7 0.0001
XP_011527448 (OMIM: 612489) PREDICTED: RING finger ( 163) 191 45.7 0.00011
XP_011527447 (OMIM: 612489) PREDICTED: RING finger ( 169) 191 45.7 0.00011
XP_016883109 (OMIM: 612489) PREDICTED: RING finger ( 169) 191 45.7 0.00011
>>NP_919445 (OMIM: 300439) E3 ubiquitin-protein ligase R (428 aa)
initn: 2913 init1: 2913 opt: 2913 Z-score: 2937.2 bits: 552.5 E(85289): 7.3e-157
Smith-Waterman score: 2913; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428)
10 20 30 40 50 60
pF1KE3 MGPPPGAGVSCRGGCGFSRLLAWCFLLALSPQAPGSRGAEAVWTAYLNVSWRVPHTGVNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 MGPPPGAGVSCRGGCGFSRLLAWCFLLALSPQAPGSRGAEAVWTAYLNVSWRVPHTGVNR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 TVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAVDIVAIMIGNLKGTKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 QRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAVDIVAIMIGNLKGTKIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 QSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 SRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 KTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 KTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TASSGYASVQGTDEPPLEEHVQSTNESLQLVNHEANSVAVDVIPHVDNPTFEEDETPNQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 TASSGYASVQGTDEPPLEEHVQSTNESLQLVNHEANSVAVDVIPHVDNPTFEEDETPNQE
370 380 390 400 410 420
pF1KE3 TAVREIKS
::::::::
NP_919 TAVREIKS
>>NP_078815 (OMIM: 300439) E3 ubiquitin-protein ligase R (402 aa)
initn: 1903 init1: 1866 opt: 1910 Z-score: 1928.9 bits: 365.9 E(85289): 1.1e-100
Smith-Waterman score: 1966; 80.5% identity (89.6% similar) in 385 aa overlap (44-428:29-402)
20 30 40 50 60 70
pF1KE3 GCGFSRLLAWCFLLALSPQAPGSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQ
.::..:.. . : :. : : ::::
NP_078 MNQENRSSFFWLLVIFTFLLKITASFSMSAYVTVTYY--NETSNYTAIETCECGVYGL
10 20 30 40 50
80 90 100 110 120 130
pF1KE3 DSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTVWGSTVQVSWLALIQRGGGCTFADKIH
::. . ::. : . . .::. .:.: :... :.:::.::. :::..::.
NP_078 ASPVANAMGVVGIPKN-NNYQACDHNTEF-------SNTKKPWIALIERGN-CTFSEKIQ
60 70 80 90 100
140 150 160 170 180 190
pF1KE3 LAYERGASGAVIFNFPGTRNEVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVI
: .:.:...::.: : : :..: :.. ::::::::::::::::::::::::::::::::
NP_078 TAGRRNADAVVIYNAPETGNQTIQMANFGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVI
110 120 130 140 150 160
200 210 220 230 240 250
pF1KE3 EVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 EVGKKHGPWVNHYSIFFVSVSFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKK
170 180 190 200 210 220
260 270 280 290 300 310
pF1KE3 AIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 AIGRLQLRTLKQGDKEIGPDGDSCAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRT
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE3 CPMCKCDILKALGIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 CPMCKCDILKALGIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGTD
290 300 310 320 330 340
380 390 400 410 420
pF1KE3 EPPLEEHVQSTNESLQLVNHEANSVAVDVIPHVDNPTFEEDETPNQETAVREIKS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_078 EPPLEEHVQSTNESLQLVNHEANSVAVDVIPHVDNPTFEEDETPNQETAVREIKS
350 360 370 380 390 400
>>NP_060233 (OMIM: 612482,617108) E3 ubiquitin-protein l (783 aa)
initn: 249 init1: 211 opt: 329 Z-score: 335.3 bits: 72.0 E(85289): 6.2e-12
Smith-Waterman score: 329; 27.8% identity (57.9% similar) in 266 aa overlap (65-321:63-316)
40 50 60 70 80 90
pF1KE3 GSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALN
:. :::.. . . :. : :. : :
NP_060 AAAVESERSAEQKAIIRVIPLKMDPTGKLNLTLEGVFAGVAEITPAEGKLMQSH-P--LY
40 50 60 70 80
100 110 120 130 140 150
pF1KE3 ACNPHTNFTVPTVWGSTVQVSWLALIQRGGGC-TFADKIHLAYERGASGAVIFNFPGTRN
:: . .. . : :.. : : ..:.: ..: ::::: ::.:.. :
NP_060 LCNASDDDNLEPGFISIVKLESPRRAPR--PCLSLASKARMAGERGAS-AVLFDITEDRA
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE3 EVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSV
. ...: .. ...: . . :... . .. .. . ::. :. : .. ....:
NP_060 AAEQLQQPLGLTWPVVLIWGNDAEKLMEFVYKNQKAHVRIEL-KEPPAWPDYDVWILMTV
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE3 --SFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIG
..:.: :.: . : :..: . .:: : .. : : : . .:. :
NP_060 VGTIFVIILASV----LRIRCRPRHSRPDPLQQRTAWAISQLATRRYQA-SCRQARGEWP
210 220 230 240 250 260
280 290 300 310 320
pF1KE3 PDGDSC------AVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKAL
.:.:: :.:.: .. .. .:...: : ::..:::::: .:::::.: .:
NP_060 DSGSSCSSAPVCAICLEEFSEGQELRVISCLHEFHRNCVDPWLHQHRTCPLCMFNITEGD
270 280 290 300 310 320
330 340 350 360 370 380
pF1KE3 GIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGTDEPPLEEHVQSTN
NP_060 SFSQSLGPSRSYQEPGRRLHLIRQHPGHAHYHLPAAYLLGPSRSAVARPPRPGPFLPSQE
330 340 350 360 370 380
>>NP_001292473 (OMIM: 612482,617108) E3 ubiquitin-protei (783 aa)
initn: 249 init1: 211 opt: 329 Z-score: 335.3 bits: 72.0 E(85289): 6.2e-12
Smith-Waterman score: 329; 27.8% identity (57.9% similar) in 266 aa overlap (65-321:63-316)
40 50 60 70 80 90
pF1KE3 GSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALN
:. :::.. . . :. : :. : :
NP_001 AAAVESERSAEQKAIIRVIPLKMDPTGKLNLTLEGVFAGVAEITPAEGKLMQSH-P--LY
40 50 60 70 80
100 110 120 130 140 150
pF1KE3 ACNPHTNFTVPTVWGSTVQVSWLALIQRGGGC-TFADKIHLAYERGASGAVIFNFPGTRN
:: . .. . : :.. : : ..:.: ..: ::::: ::.:.. :
NP_001 LCNASDDDNLEPGFISIVKLESPRRAPR--PCLSLASKARMAGERGAS-AVLFDITEDRA
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE3 EVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSV
. ...: .. ...: . . :... . .. .. . ::. :. : .. ....:
NP_001 AAEQLQQPLGLTWPVVLIWGNDAEKLMEFVYKNQKAHVRIEL-KEPPAWPDYDVWILMTV
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE3 --SFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIG
..:.: :.: . : :..: . .:: : .. : : : . .:. :
NP_001 VGTIFVIILASV----LRIRCRPRHSRPDPLQQRTAWAISQLATRRYQA-SCRQARGEWP
210 220 230 240 250 260
280 290 300 310 320
pF1KE3 PDGDSC------AVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKAL
.:.:: :.:.: .. .. .:...: : ::..:::::: .:::::.: .:
NP_001 DSGSSCSSAPVCAICLEEFSEGQELRVISCLHEFHRNCVDPWLHQHRTCPLCMFNITEGD
270 280 290 300 310 320
330 340 350 360 370 380
pF1KE3 GIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGTDEPPLEEHVQSTN
NP_001 SFSQSLGPSRSYQEPGRRLHLIRQHPGHAHYHLPAAYLLGPSRSAVARPPRPGPFLPSQE
330 340 350 360 370 380
>>XP_011523257 (OMIM: 612482,617108) PREDICTED: E3 ubiqu (869 aa)
initn: 249 init1: 211 opt: 329 Z-score: 334.7 bits: 72.0 E(85289): 6.7e-12
Smith-Waterman score: 329; 27.8% identity (57.9% similar) in 266 aa overlap (65-321:63-316)
40 50 60 70 80 90
pF1KE3 GSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALN
:. :::.. . . :. : :. : :
XP_011 AAAVESERSAEQKAIIRVIPLKMDPTGKLNLTLEGVFAGVAEITPAEGKLMQSH-P--LY
40 50 60 70 80
100 110 120 130 140 150
pF1KE3 ACNPHTNFTVPTVWGSTVQVSWLALIQRGGGC-TFADKIHLAYERGASGAVIFNFPGTRN
:: . .. . : :.. : : ..:.: ..: ::::: ::.:.. :
XP_011 LCNASDDDNLEPGFISIVKLESPRRAPR--PCLSLASKARMAGERGAS-AVLFDITEDRA
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE3 EVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSV
. ...: .. ...: . . :... . .. .. . ::. :. : .. ....:
XP_011 AAEQLQQPLGLTWPVVLIWGNDAEKLMEFVYKNQKAHVRIEL-KEPPAWPDYDVWILMTV
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE3 --SFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIG
..:.: :.: . : :..: . .:: : .. : : : . .:. :
XP_011 VGTIFVIILASV----LRIRCRPRHSRPDPLQQRTAWAISQLATRRYQA-SCRQARGEWP
210 220 230 240 250 260
280 290 300 310 320
pF1KE3 PDGDSC------AVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKAL
.:.:: :.:.: .. .. .:...: : ::..:::::: .:::::.: .:
XP_011 DSGSSCSSAPVCAICLEEFSEGQELRVISCLHEFHRNCVDPWLHQHRTCPLCMFNITEGD
270 280 290 300 310 320
330 340 350 360 370 380
pF1KE3 GIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGTDEPPLEEHVQSTN
XP_011 SFSQSLGPSRSYQEPGRRLHLIRQHPGHAHYHLPAAYLLGPSRSAVARPPRPGPFLPSQE
330 340 350 360 370 380
>>XP_016880289 (OMIM: 612482,617108) PREDICTED: E3 ubiqu (869 aa)
initn: 249 init1: 211 opt: 329 Z-score: 334.7 bits: 72.0 E(85289): 6.7e-12
Smith-Waterman score: 329; 27.8% identity (57.9% similar) in 266 aa overlap (65-321:63-316)
40 50 60 70 80 90
pF1KE3 GSRGAEAVWTAYLNVSWRVPHTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALN
:. :::.. . . :. : :. : :
XP_016 AAAVESERSAEQKAIIRVIPLKMDPTGKLNLTLEGVFAGVAEITPAEGKLMQSH-P--LY
40 50 60 70 80
100 110 120 130 140 150
pF1KE3 ACNPHTNFTVPTVWGSTVQVSWLALIQRGGGC-TFADKIHLAYERGASGAVIFNFPGTRN
:: . .. . : :.. : : ..:.: ..: ::::: ::.:.. :
XP_016 LCNASDDDNLEPGFISIVKLESPRRAPR--PCLSLASKARMAGERGAS-AVLFDITEDRA
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE3 EVIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSV
. ...: .. ...: . . :... . .. .. . ::. :. : .. ....:
XP_016 AAEQLQQPLGLTWPVVLIWGNDAEKLMEFVYKNQKAHVRIEL-KEPPAWPDYDVWILMTV
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE3 --SFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIG
..:.: :.: . : :..: . .:: : .. : : : . .:. :
XP_016 VGTIFVIILASV----LRIRCRPRHSRPDPLQQRTAWAISQLATRRYQA-SCRQARGEWP
210 220 230 240 250 260
280 290 300 310 320
pF1KE3 PDGDSC------AVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKAL
.:.:: :.:.: .. .. .:...: : ::..:::::: .:::::.: .:
XP_016 DSGSSCSSAPVCAICLEEFSEGQELRVISCLHEFHRNCVDPWLHQHRTCPLCMFNITEGD
270 280 290 300 310 320
330 340 350 360 370 380
pF1KE3 GIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGTDEPPLEEHVQSTN
XP_016 SFSQSLGPSRSYQEPGRRLHLIRQHPGHAHYHLPAAYLLGPSRSAVARPPRPGPFLPSQE
330 340 350 360 370 380
>>NP_001292474 (OMIM: 612482,617108) E3 ubiquitin-protei (656 aa)
initn: 211 init1: 211 opt: 298 Z-score: 305.1 bits: 66.1 E(85289): 3e-10
Smith-Waterman score: 298; 29.1% identity (61.2% similar) in 196 aa overlap (134-321:1-189)
110 120 130 140 150 160
pF1KE3 VPTVWGSTVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGA
.: ::::: ::.:.. : . ...: .
NP_001 MAGERGAS-AVLFDITEDRAAAEQLQQPLG
10 20
170 180 190 200 210 220
pF1KE3 VDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSV--SFFIITAA
. ...: . . :... . .. .. . ::. :. : .. ....: ..:.: :
NP_001 LTWPVVLIWGNDAEKLMEFVYKNQKAHVRIEL-KEPPAWPDYDVWILMTVVGTIFVIILA
30 40 50 60 70 80
230 240 250 260 270
pF1KE3 TVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSC----
.: . : :..: . .:: : .. : : : . .:. : .:.::
NP_001 SV----LRIRCRPRHSRPDPLQQRTAWAISQLATRRYQA-SCRQARGEWPDSGSSCSSAP
90 100 110 120 130 140
280 290 300 310 320 330
pF1KE3 --AVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGS
:.:.: .. .. .:...: : ::..:::::: .:::::.: .:
NP_001 VCAICLEEFSEGQELRVISCLHEFHRNCVDPWLHQHRTCPLCMFNITEGDSFSQSLGPSR
150 160 170 180 190 200
340 350 360 370 380 390
pF1KE3 VSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGTDEPPLEEHVQSTNESLQLVNHEA
NP_001 SYQEPGRRLHLIRQHPGHAHYHLPAAYLLGPSRSAVARPPRPGPFLPSQEPGMGPRHHRF
210 220 230 240 250 260
>>XP_011523258 (OMIM: 612482,617108) PREDICTED: E3 ubiqu (742 aa)
initn: 211 init1: 211 opt: 298 Z-score: 304.4 bits: 66.2 E(85289): 3.2e-10
Smith-Waterman score: 298; 29.1% identity (61.2% similar) in 196 aa overlap (134-321:1-189)
110 120 130 140 150 160
pF1KE3 VPTVWGSTVQVSWLALIQRGGGCTFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGA
.: ::::: ::.:.. : . ...: .
XP_011 MAGERGAS-AVLFDITEDRAAAEQLQQPLG
10 20
170 180 190 200 210 220
pF1KE3 VDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSV--SFFIITAA
. ...: . . :... . .. .. . ::. :. : .. ....: ..:.: :
XP_011 LTWPVVLIWGNDAEKLMEFVYKNQKAHVRIEL-KEPPAWPDYDVWILMTVVGTIFVIILA
30 40 50 60 70 80
230 240 250 260 270
pF1KE3 TVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDGDSC----
.: . : :..: . .:: : .. : : : . .:. : .:.::
XP_011 SV----LRIRCRPRHSRPDPLQQRTAWAISQLATRRYQA-SCRQARGEWPDSGSSCSSAP
90 100 110 120 130 140
280 290 300 310 320 330
pF1KE3 --AVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGS
:.:.: .. .. .:...: : ::..:::::: .:::::.: .:
XP_011 VCAICLEEFSEGQELRVISCLHEFHRNCVDPWLHQHRTCPLCMFNITEGDSFSQSLGPSR
150 160 170 180 190 200
340 350 360 370 380 390
pF1KE3 VSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGTDEPPLEEHVQSTNESLQLVNHEA
XP_011 SYQEPGRRLHLIRQHPGHAHYHLPAAYLLGPSRSAVARPPRPGPFLPSQEPGMGPRHHRF
210 220 230 240 250 260
>>NP_001193927 (OMIM: 612062) E3 ubiquitin-protein ligas (936 aa)
initn: 261 init1: 222 opt: 280 Z-score: 285.0 bits: 62.9 E(85289): 3.9e-09
Smith-Waterman score: 287; 25.3% identity (54.7% similar) in 316 aa overlap (25-326:39-342)
10 20 30 40 50
pF1KE3 MGPPPGAGVSCRGGCGFSRLLAWCFLLALSPQAPGSRGAEAVWTAYLNVSWRVP
.::.: : : .:.: ::...:
NP_001 PGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAFVEVVLFES
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 HTGVNRTVWELSEEGVYGQDSPLEPVAGVLVPPDGPGALNACNPHTNFTVPTV-WGSTVQ
. . :.. . : ... . . : .: : :. :: . . . : ..:.
NP_001 SPSGDYTTYTTGLTGRFSRAGATLSAEGEIVQMH-P--LGLCNNNDEEDLYEYGWVGVVK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 VSWLALIQRGGGC-TFADKIHLAYERGASGAVIFNFPGTRNEVIPMSHPGAVDIVAIMIG
. : . : : : . : .:::. ::::. . :.: . . :. : . .
NP_001 LEQPELDPK--PCLTVLGKAKRAVQRGAT-AVIFDV-SENPEAIDQLNQGSEDPLKRPVV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 NLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSV--SFFIITAATVGYFIFYS
.::. .. .. .. : .. .: : . : ... .::.... . .:.
NP_001 YVKGADAIK-LMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVC--LILLV
190 200 210 220 230
240 250 260 270 280
pF1KE3 ARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGPDG--DS--------CAVC
.:.. :.:. .: : ..: . . .. . ..: .: : : :. ::.:
NP_001 KIKLKQRRSQNSMNR-LAVQALEKMETRKFNSKSKGRRE-GSCGALDTLSSSSTSDCAIC
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE3 IELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDILKALGIEVDVEDGSVSLQV
.: : .. .:.. :.: ::. :::::::.:.::: :. .:.. :
NP_001 LEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNLSR
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE3 PVSNEISNSASSHEEDNRSETASSGYASVQGTDEPPLEEHVQSTNESLQLVNHEANSVAV
NP_001 GRQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLYSPQTPAYI
360 370 380 390 400 410
>>NP_115549 (OMIM: 612062) E3 ubiquitin-protein ligase Z (836 aa)
initn: 222 init1: 222 opt: 263 Z-score: 268.5 bits: 59.7 E(85289): 3.2e-08
Smith-Waterman score: 270; 27.6% identity (58.4% similar) in 214 aa overlap (126-326:36-242)
100 110 120 130 140 150
pF1KE3 CNPHTNFTVPTVWGSTVQVSWLALIQRGGGC-TFADKIHLAYERGASGAVIFNFPGTRNE
: : : . : .:::. ::::. . :
NP_115 LCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGAT-AVIFDV-SENPE
10 20 30 40 50 60
160 170 180 190 200 210
pF1KE3 VIPMSHPGAVDIVAIMIGNLKGTKILQSIQRGIQVTMVIEVGKKHGPWVNHYSIFFVSV-
.: . . :. : . . .::. .. .. .. : .. .: : . : ...
NP_115 AIDQLNQGSEDPLKRPVVYVKGADAIK-LMNIVNKQKVARARIQHRPPRQPTEYFDMGIF
70 80 90 100 110 120
220 230 240 250 260 270
pF1KE3 -SFFIITAATVGYFIFYSARRLRNARAQSRKQRQLKADAKKAIGRLQLRTLKQGDKEIGP
.::.... . .:. .:.. :.:. .: : ..: . . .. . ..: .: :
NP_115 LAFFVVVSLVC--LILLVKIKLKQRRSQNSMNR-LAVQALEKMETRKFNSKSKGRRE-GS
130 140 150 160 170
280 290 300 310 320
pF1KE3 DG--DS--------CAVCIELYKPNDLVRILTCNHIFHKTCVDPWLLEHRTCPMCKCDIL
: :. ::.:.: : .. .:.. :.: ::. :::::::.:.::: :. .:.
NP_115 CGALDTLSSSSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNII
180 190 200 210 220 230
330 340 350 360 370 380
pF1KE3 KALGIEVDVEDGSVSLQVPVSNEISNSASSHEEDNRSETASSGYASVQGTDEPPLEEHVQ
. :
NP_115 EQKGNPSAVCVETSNLSRGRQQRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLT
240 250 260 270 280 290
428 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:48:52 2016 done: Sun Nov 6 04:48:53 2016
Total Scan time: 9.430 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]