Result of FASTA (omim) for
pFN21AE1228
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1228, 317 aa
1>>>pF1KE1228 317 - 317 aa - 317 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9464+/-0.00037; mu= 18.3607+/- 0.023
mean_var=75.7903+/-15.622, 0's: 0 Z-trim(113.7): 29 B-trim: 233 in 1/54
Lambda= 0.147322
statistics sampled from 23232 (23240) to 23232 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.272), width: 16
Scan time: 6.930
The best scores are: opt bits E(85289)
NP_071427 (OMIM: 300459) tenomodulin [Homo sapiens ( 317) 2230 483.3 2.7e-136
NP_001011705 (OMIM: 605147) leukocyte cell-derived ( 333) 706 159.4 9.1e-39
NP_008946 (OMIM: 605147) leukocyte cell-derived ch ( 334) 696 157.3 4e-38
XP_011533200 (OMIM: 605147) PREDICTED: leukocyte c ( 364) 484 112.3 1.5e-24
XP_011533202 (OMIM: 605147) PREDICTED: leukocyte c ( 323) 476 110.5 4.6e-24
XP_011533201 (OMIM: 605147) PREDICTED: leukocyte c ( 327) 476 110.5 4.7e-24
XP_011533199 (OMIM: 605147) PREDICTED: leukocyte c ( 365) 474 110.2 6.8e-24
>>NP_071427 (OMIM: 300459) tenomodulin [Homo sapiens] (317 aa)
initn: 2230 init1: 2230 opt: 2230 Z-score: 2567.8 bits: 483.3 E(85289): 2.7e-136
Smith-Waterman score: 2230; 100.0% identity (100.0% similar) in 317 aa overlap (1-317:1-317)
10 20 30 40 50 60
pF1KE1 MAKNPPENCEDCHILNAEAFKSKKICKSLKICGLVFGILALTLIVLFWGSKHFWPEVPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MAKNPPENCEDCHILNAEAFKSKKICKSLKICGLVFGILALTLIVLFWGSKHFWPEVPKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 AYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 FIKTQIKVIPEFSEPEEEIDENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 FIKTQIKVIPEFSEPEEEIDENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 VTMYWINPTLISVSELQDFEEEGEDLHFPANEKKGIEQNEQWVVPQVKVEKTRHARQASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VTMYWINPTLISVSELQDFEEEGEDLHFPANEKKGIEQNEQWVVPQVKVEKTRHARQASE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 EELPINDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 EELPINDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVIC
250 260 270 280 290 300
310
pF1KE1 RVIMPCNWWVARMLGRV
:::::::::::::::::
NP_071 RVIMPCNWWVARMLGRV
310
>>NP_001011705 (OMIM: 605147) leukocyte cell-derived che (333 aa)
initn: 636 init1: 352 opt: 706 Z-score: 817.0 bits: 159.4 E(85289): 9.1e-39
Smith-Waterman score: 706; 36.1% identity (65.7% similar) in 324 aa overlap (6-317:15-333)
10 20 30 40
pF1KE1 MAKNPPENCEDCH--ILNAEAFKSKKICKSLKICGLVFGILALTLIVLFWG
:.. : : . . : .. . ::. ..:. :. :. :
NP_001 MTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 SKHFWPEVPKKAYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSGNGTDETLEVHDFKNGY
. .:: .. :....:. ::. . :::: . : :. :.:..:.. :.::.::
NP_001 AFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGI
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 TGIYFVGLQKCFIKTQIKV-IPEFSE-PEEEID---ENEEITTTFFEQSVIWVPAEKPIE
::: :.: .::.::.:.:. ::: . .. :. :.. . . . :.:.::: ...:..
NP_001 TGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 NRDFLKNSKILEICDNVTMYWINPTLISVSELQDFEEEGEDLHFPANEKK---GIEQNEQ
. .:: .::.::.: .. ..:..:: . :.: ..: :.. :. : ..:
NP_001 DNSFL-SSKVLELCGDLPIFWLKPTYPK--EIQRERREVVRKIVPTTTKRPHSGPRSNPG
190 200 210 220 230
230 240 250 260 270
pF1KE1 WVVPQVKVEKTRHARQASEEELPINDYTENG--IEFDPMLDERGYCCIYCRRGNRYCRRV
. ... : ... :. : : : ..: . ::: ::..: ::: :::. .:...
NP_001 --AGRLNNETRPSVQEDSQAFNPDNPYHQEGESMTFDPRLDHEGICCIECRRSYTHCQKI
240 250 260 270 280 290
280 290 300 310
pF1KE1 CEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV
:::: ::::.:: ::: : :::::::.:::::.:: :
NP_001 CEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV
300 310 320 330
>>NP_008946 (OMIM: 605147) leukocyte cell-derived chemot (334 aa)
initn: 648 init1: 364 opt: 696 Z-score: 805.5 bits: 157.3 E(85289): 4e-38
Smith-Waterman score: 696; 35.7% identity (65.5% similar) in 325 aa overlap (6-317:15-334)
10 20 30 40
pF1KE1 MAKNPPENCEDCH--ILNAEAFKSKKICKSLKICGLVFGILALTLIVLFWG
:.. : : . . : .. . ::. ..:. :. :. :
NP_008 MTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 SKHFWPEVPKKAYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSGNGTDETLEVHDFKNGY
. .:: .. :....:. ::. . :::: . : :. :.:..:.. :.::.::
NP_008 AFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGI
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE1 TGIYFVGLQKCFIKTQIKV-IPEFSE-PEEEID---ENEEITTTFFEQSVIWVPAEKPIE
::: :.: .::.::.:.:. ::: . .. :. :.. . . . :.:.::: ...:..
NP_008 TGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE1 NRDFLKNSKILEICDNVTMYWINPTLISVSELQDFEEEGEDLHFPANEKK---GIEQNEQ
. .:: .::.::.: .. ..:..:: . :.: ..: :.. :. : ..:
NP_008 DNSFL-SSKVLELCGDLPIFWLKPTYPK--EIQRERREVVRKIVPTTTKRPHSGPRSNPG
190 200 210 220 230
230 240 250 260 270
pF1KE1 WVVPQVKVEKTRHARQASEEELPINDYTEN---GIEFDPMLDERGYCCIYCRRGNRYCRR
. ... : ... :. : : : .. .. ::: ::..: ::: :::. .:..
NP_008 --AGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQK
240 250 260 270 280 290
280 290 300 310
pF1KE1 VCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV
.:::: ::::.:: ::: : :::::::.:::::.:: :
NP_008 ICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV
300 310 320 330
>>XP_011533200 (OMIM: 605147) PREDICTED: leukocyte cell- (364 aa)
initn: 636 init1: 352 opt: 484 Z-score: 561.5 bits: 112.3 E(85289): 1.5e-24
Smith-Waterman score: 706; 35.9% identity (65.6% similar) in 326 aa overlap (6-317:42-364)
10 20 30
pF1KE1 MAKNPPENCEDCH--ILNAEAFKSKKICKSLKICG
:.. : : . . : .. . ::. .
XP_011 QGAQGVSKCLTPPAANMTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGA
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 LVFGILALTLIVLFWGSKHFWPEVPKKAYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSG
.:. :. :. :. .:: .. :....:. ::. . :::: . : :. :
XP_011 VVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMG
80 90 100 110 120 130
100 110 120 130 140
pF1KE1 NGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKV-IPEFSE-PEEEID---ENEEITTT
.:..:.. :.::.:: ::: :.: .::.::.:.:. ::: . .. :. :.. . .
XP_011 SGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVK
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE1 FFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLIS--VSELQDFEEEGEDL
. :.:.::: ...:... .:: .::.::.: .. ..:..:: . .:.: ..:
XP_011 YEENSLIWVAVDQPVKDNSFL-SSKVLELCGDLPIFWLKPTYPKEIFAEIQRERREVVRK
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE1 HFPANEKK---GIEQNEQWVVPQVKVEKTRHARQASEEELPINDYTENG--IEFDPMLDE
:.. :. : ..: . ... : ... :. : : : ..: . ::: ::.
XP_011 IVPTTTKRPHSGPRSNPG--AGRLNNETRPSVQEDSQAFNPDNPYHQEGESMTFDPRLDH
260 270 280 290 300
270 280 290 300 310
pF1KE1 RGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV
.: ::: :::. .:...:::: ::::.:: ::: : :::::::.:::::.:: :
XP_011 EGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV
310 320 330 340 350 360
>>XP_011533202 (OMIM: 605147) PREDICTED: leukocyte cell- (323 aa)
initn: 559 init1: 364 opt: 476 Z-score: 553.0 bits: 110.5 E(85289): 4.6e-24
Smith-Waterman score: 552; 31.6% identity (58.8% similar) in 320 aa overlap (6-317:42-323)
10 20 30
pF1KE1 MAKNPPENCEDCH--ILNAEAFKSKKICKSLKICG
:.. : : . . : .. . ::. .
XP_011 QGAQGVSKCLTPPAANMTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGA
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 LVFGILALTLIVLFWGSKHFWPEVPKKAYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSG
.:. :. :. :. .:: .. :....:. ::. . :::: . : :. :
XP_011 VVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMG
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 NGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEIDENEEITTTFFEQS
.:..:.. :.::.: . :..: . . :.:
XP_011 SGAEEAIAVNDFQN-----------------EGKIMP----------------VKYEENS
140 150
160 170 180 190 200 210
pF1KE1 VIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLISVSELQDFEEEGEDLHFPANEK
.::: ...:... .:: .::.::.: .. ..:..:: . :.: ..: :.. :
XP_011 LIWVAVDQPVKDNSFL-SSKVLELCGDLPIFWLKPTYPK--EIQRERREVVRKIVPTTTK
160 170 180 190 200 210
220 230 240 250 260
pF1KE1 K---GIEQNEQWVVPQVKVEKTRHARQASEEELPINDYTEN---GIEFDPMLDERGYCCI
. : ..: . ... : ... :. : : : .. .. ::: ::..: :::
XP_011 RPHSGPRSNPG--AGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCI
220 230 240 250 260 270
270 280 290 300 310
pF1KE1 YCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV
:::. .:...:::: ::::.:: ::: : :::::::.:::::.:: :
XP_011 ECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV
280 290 300 310 320
>>XP_011533201 (OMIM: 605147) PREDICTED: leukocyte cell- (327 aa)
initn: 559 init1: 364 opt: 476 Z-score: 552.9 bits: 110.5 E(85289): 4.7e-24
Smith-Waterman score: 552; 31.4% identity (58.7% similar) in 322 aa overlap (6-317:42-327)
10 20 30
pF1KE1 MAKNPPENCEDCH--ILNAEAFKSKKICKSLKICG
:.. : : . . : .. . ::. .
XP_011 QGAQGVSKCLTPPAANMTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGA
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 LVFGILALTLIVLFWGSKHFWPEVPKKAYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSG
.:. :. :. :. .:: .. :....:. ::. . :::: . : :. :
XP_011 VVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMG
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE1 NGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEIDENEEITTTFFEQS
.:..:.. :.::.: . :..: . . :.:
XP_011 SGAEEAIAVNDFQN-----------------EGKIMP----------------VKYEENS
140 150
160 170 180 190 200 210
pF1KE1 VIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLIS--VSELQDFEEEGEDLHFPAN
.::: ...:... .:: .::.::.: .. ..:..:: . .:.: ..: :..
XP_011 LIWVAVDQPVKDNSFL-SSKVLELCGDLPIFWLKPTYPKEIFAEIQRERREVVRKIVPTT
160 170 180 190 200 210
220 230 240 250 260
pF1KE1 EKK---GIEQNEQWVVPQVKVEKTRHARQASEEELPINDYTEN---GIEFDPMLDERGYC
:. : ..: . ... : ... :. : : : .. .. ::: ::..: :
XP_011 TKRPHSGPRSNPG--AGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGIC
220 230 240 250 260 270
270 280 290 300 310
pF1KE1 CIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV
:: :::. .:...:::: ::::.:: ::: : :::::::.:::::.:: :
XP_011 CIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV
280 290 300 310 320
>>XP_011533199 (OMIM: 605147) PREDICTED: leukocyte cell- (365 aa)
initn: 648 init1: 364 opt: 474 Z-score: 550.0 bits: 110.2 E(85289): 6.8e-24
Smith-Waterman score: 696; 35.5% identity (65.4% similar) in 327 aa overlap (6-317:42-365)
10 20 30
pF1KE1 MAKNPPENCEDCH--ILNAEAFKSKKICKSLKICG
:.. : : . . : .. . ::. .
XP_011 QGAQGVSKCLTPPAANMTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGA
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE1 LVFGILALTLIVLFWGSKHFWPEVPKKAYDMEHTFYSNGEKKKIYMEIDPVTRTEIFRSG
.:. :. :. :. .:: .. :....:. ::. . :::: . : :. :
XP_011 VVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMG
80 90 100 110 120 130
100 110 120 130 140
pF1KE1 NGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKV-IPEFSE-PEEEID---ENEEITTT
.:..:.. :.::.:: ::: :.: .::.::.:.:. ::: . .. :. :.. . .
XP_011 SGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVK
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE1 FFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLIS--VSELQDFEEEGEDL
. :.:.::: ...:... .:: .::.::.: .. ..:..:: . .:.: ..:
XP_011 YEENSLIWVAVDQPVKDNSFL-SSKVLELCGDLPIFWLKPTYPKEIFAEIQRERREVVRK
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE1 HFPANEKK---GIEQNEQWVVPQVKVEKTRHARQASEEELPINDYTEN---GIEFDPMLD
:.. :. : ..: . ... : ... :. : : : .. .. ::: ::
XP_011 IVPTTTKRPHSGPRSNPG--AGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLD
260 270 280 290 300
270 280 290 300 310
pF1KE1 ERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV
..: ::: :::. .:...:::: ::::.:: ::: : :::::::.:::::.:: :
XP_011 HEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV
310 320 330 340 350 360
317 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:44:48 2016 done: Sun Nov 6 12:44:49 2016
Total Scan time: 6.930 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]