Result of FASTA (omim) for
pFN21AE3167
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3167, 392 aa
1>>>pF1KE3167 392 - 392 aa - 392 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8446+/-0.000344; mu= 19.7764+/- 0.022
mean_var=67.8414+/-13.817, 0's: 0 Z-trim(114.7): 65 B-trim: 492 in 1/51
Lambda= 0.155714
statistics sampled from 24594 (24668) to 24594 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.289), width: 16
Scan time: 8.500
The best scores are: opt bits E(85289)
NP_005439 (OMIM: 300247,300510) bone morphogenetic ( 392) 2686 612.3 6.2e-175
XP_011541613 (OMIM: 601918) PREDICTED: growth/diff ( 276) 462 112.6 1.2e-24
NP_001275755 (OMIM: 601918) growth/differentiation ( 366) 462 112.7 1.5e-24
NP_001275757 (OMIM: 601918) growth/differentiation ( 366) 462 112.7 1.5e-24
XP_011541611 (OMIM: 601918) PREDICTED: growth/diff ( 366) 462 112.7 1.5e-24
NP_001275753 (OMIM: 601918) growth/differentiation ( 366) 462 112.7 1.5e-24
XP_005272014 (OMIM: 601918) PREDICTED: growth/diff ( 366) 462 112.7 1.5e-24
XP_011541612 (OMIM: 601918) PREDICTED: growth/diff ( 366) 462 112.7 1.5e-24
NP_001275756 (OMIM: 601918) growth/differentiation ( 366) 462 112.7 1.5e-24
NP_001275754 (OMIM: 601918) growth/differentiation ( 366) 462 112.7 1.5e-24
XP_006714648 (OMIM: 601918) PREDICTED: growth/diff ( 366) 462 112.7 1.5e-24
XP_011541610 (OMIM: 601918) PREDICTED: growth/diff ( 454) 462 112.7 1.7e-24
NP_005251 (OMIM: 601918) growth/differentiation fa ( 454) 462 112.7 1.7e-24
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501) 394 97.5 7.4e-20
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501) 394 97.5 7.4e-20
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501) 394 97.5 7.4e-20
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455) 387 95.9 2.1e-19
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450) 377 93.7 9.7e-19
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239) 371 92.1 1.5e-18
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454) 371 92.3 2.5e-18
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396) 360 89.8 1.2e-17
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513) 361 90.1 1.3e-17
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402) 355 88.7 2.7e-17
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240) 346 86.5 7.5e-17
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345) 343 85.9 1.6e-16
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345) 343 85.9 1.6e-16
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408) 343 86.0 1.8e-16
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408) 343 86.0 1.8e-16
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408) 343 86.0 1.8e-16
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408) 343 86.0 1.8e-16
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431) 342 85.8 2.2e-16
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364) 316 79.9 1.1e-14
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424) 316 79.9 1.2e-14
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427) 299 76.1 1.8e-13
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429) 296 75.4 2.8e-13
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372) 293 74.7 4e-13
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347) 287 73.3 9.7e-13
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214) 283 72.3 1.3e-12
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472) 285 73.0 1.7e-12
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478) 263 68.1 5.2e-11
XP_006719257 (OMIM: 603936) PREDICTED: growth/diff ( 407) 247 64.4 5.5e-10
NP_005802 (OMIM: 603936) growth/differentiation fa ( 407) 247 64.4 5.5e-10
XP_011540324 (OMIM: 602284) PREDICTED: bone morpho ( 357) 243 63.5 9.4e-10
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426) 238 62.4 2.3e-09
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426) 238 62.4 2.3e-09
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483) 238 62.5 2.6e-09
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548) 238 62.5 2.8e-09
NP_005250 (OMIM: 601788,614160) growth/differentia ( 375) 231 60.8 6.3e-09
NP_004855 (OMIM: 605312) growth/differentiation fa ( 308) 221 58.5 2.6e-08
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407) 221 58.6 3.2e-08
>>NP_005439 (OMIM: 300247,300510) bone morphogenetic pro (392 aa)
initn: 2686 init1: 2686 opt: 2686 Z-score: 3261.6 bits: 612.3 E(85289): 6.2e-175
Smith-Waterman score: 2686; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392)
10 20 30 40 50 60
pF1KE3 MVLLSILRILFLCELVLFMEHRAQMAEGGQSSIALLAEAPTLPLIEELLEESPGEQPRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MVLLSILRILFLCELVLFMEHRAQMAEGGQSSIALLAEAPTLPLIEELLEESPGEQPRKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVKPLTNVARPHRGTWHIQILGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVKPLTNVARPHRGTWHIQILGFP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LRPNRGLYQLVRATVVYRHHLQLTRFNLSCHVEPWVQKNPTNHFPSSEGDSSKPSLMSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LRPNRGLYQLVRATVVYRHHLQLTRFNLSCHVEPWVQKNPTNHFPSSEGDSSKPSLMSNA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 WKEMDITQLVQQRFWNNKGHRILRLRFMCQQQKDSGGLELWHGTSSLDIAFLLLYFNDTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WKEMDITQLVQQRFWNNKGHRILRLRFMCQQQKDSGGLELWHGTSSLDIAFLLLYFNDTH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KSIRKAKFLPRGMEEFMERESLLRRTRQADGISAEVTASSSKHSGPENNQCSLHPFQISF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KSIRKAKFLPRGMEEFMERESLLRRTRQADGISAEVTASSSKHSGPENNQCSLHPFQISF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 RQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPY
310 320 330 340 350 360
370 380 390
pF1KE3 KYVPISVLMIEANGSILYKEYEGMIAESCTCR
::::::::::::::::::::::::::::::::
NP_005 KYVPISVLMIEANGSILYKEYEGMIAESCTCR
370 380 390
>>XP_011541613 (OMIM: 601918) PREDICTED: growth/differen (276 aa)
initn: 489 init1: 462 opt: 462 Z-score: 563.5 bits: 112.6 E(85289): 1.2e-24
Smith-Waterman score: 488; 39.0% identity (56.6% similar) in 251 aa overlap (181-392:33-276)
160 170 180 190 200
pF1KE3 HVEPWVQKNPTNHFPSSEGDSSKPSLMSNAWKEMDITQLVQQRFWNNKGHRILRLRFMC-
: ..:.:.:.: .:: . . : :
XP_011 KEPKSSSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIHMSINFTCM
10 20 30 40 50 60
210 220 230 240
pF1KE3 --QQQKDSGGLELWHGTSSLDIAFLLLYFNDT-----------HKSIRKAK---------
: .. :. :.. : : :.::.::: : . : ..
XP_011 KDQLEHPSAQNGLFNMT--LVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQGPDQERSLS
70 80 90 100 110 120
250 260 270 280 290
pF1KE3 FLPRGMEEFME--RESLLRRTRQADGISAEVTASSSKHSGPEN--------------NQC
: : :: : : : :. : . .:.:. .: :: . :.:
XP_011 AYPVG-EEAAEDGRSSHHRHRRGQETVSSEL----KKPLGPASFNLSEYFRQFLLPQNEC
130 140 150 160 170
300 310 320 330 340 350
pF1KE3 SLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQS
:: :..:: :: ::.::.:: :.: :::: : :.. .:: :...::.: . .:.:
XP_011 ELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEKLDSS
180 190 200 210 220 230
360 370 380 390
pF1KE3 VPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR
:::::::: :: :.::: :: .::: ::::: ::: .::::
XP_011 VPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR
240 250 260 270
>>NP_001275755 (OMIM: 601918) growth/differentiation fac (366 aa)
initn: 541 init1: 462 opt: 462 Z-score: 561.9 bits: 112.7 E(85289): 1.5e-24
Smith-Waterman score: 531; 34.0% identity (54.1% similar) in 379 aa overlap (70-392:1-366)
40 50 60 70 80 90
pF1KE3 PTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVK
: .::. : ..: :. ::. . :::
NP_001 MKKLYKTYATKEGIPKSNRSHLYNTVRLFT
10 20 30
100 110 120 130 140
pF1KE3 PLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQ-LTRFNLS---------
: : :. . :. :. : . :..: : :.: .: :. . .:..
NP_001 PCTR----HKQAPGDQVTGI-LPSVELLFNLDRITTV-EHLLKSVLLYNINNSVSFSSAV
40 50 60 70 80
150 160 170 180 190 200
pF1KE3 ---CHV---EPWVQKNPTNHFPSSEGDSSKPSL-MSNAWKEMDITQLVQQRFWNNKGHRI
:.. :: .. .. : : .:. . .. : ..:.:.:.: .::
NP_001 KCVCNLMIKEPKSSSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIH
90 100 110 120 130 140
210 220 230 240
pF1KE3 LRLRFMC---QQQKDSGGLELWHGTSSLDIAFLLLYFNDT-----------HKSIRKAK-
. . : : : .. :. :.. : : :.::.::: : . : ..
NP_001 MSINFTCMKDQLEHPSAQNGLFNMT--LVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQG
150 160 170 180 190 200
250 260 270 280
pF1KE3 --------FLPRGMEEFME--RESLLRRTRQADGISAEVTASSSKHSGPEN---------
: : :: : : : :. : . .:.:. .: :: .
NP_001 PDQERSLSAYPVG-EEAAEDGRSSHHRHRRGQETVSSEL----KKPLGPASFNLSEYFRQ
210 220 230 240 250
290 300 310 320 330 340
pF1KE3 -----NQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNL
:.: :: :..:: :: ::.::.:: :.: :::: : :.. .:: :...::.
NP_001 FLLPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNI
260 270 280 290 300 310
350 360 370 380 390
pF1KE3 INQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR
: . .:.::::::::: :: :.::: :: .::: ::::: ::: .::::
NP_001 IYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR
320 330 340 350 360
>>NP_001275757 (OMIM: 601918) growth/differentiation fac (366 aa)
initn: 541 init1: 462 opt: 462 Z-score: 561.9 bits: 112.7 E(85289): 1.5e-24
Smith-Waterman score: 531; 34.0% identity (54.1% similar) in 379 aa overlap (70-392:1-366)
40 50 60 70 80 90
pF1KE3 PTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVK
: .::. : ..: :. ::. . :::
NP_001 MKKLYKTYATKEGIPKSNRSHLYNTVRLFT
10 20 30
100 110 120 130 140
pF1KE3 PLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQ-LTRFNLS---------
: : :. . :. :. : . :..: : :.: .: :. . .:..
NP_001 PCTR----HKQAPGDQVTGI-LPSVELLFNLDRITTV-EHLLKSVLLYNINNSVSFSSAV
40 50 60 70 80
150 160 170 180 190 200
pF1KE3 ---CHV---EPWVQKNPTNHFPSSEGDSSKPSL-MSNAWKEMDITQLVQQRFWNNKGHRI
:.. :: .. .. : : .:. . .. : ..:.:.:.: .::
NP_001 KCVCNLMIKEPKSSSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIH
90 100 110 120 130 140
210 220 230 240
pF1KE3 LRLRFMC---QQQKDSGGLELWHGTSSLDIAFLLLYFNDT-----------HKSIRKAK-
. . : : : .. :. :.. : : :.::.::: : . : ..
NP_001 MSINFTCMKDQLEHPSAQNGLFNMT--LVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQG
150 160 170 180 190 200
250 260 270 280
pF1KE3 --------FLPRGMEEFME--RESLLRRTRQADGISAEVTASSSKHSGPEN---------
: : :: : : : :. : . .:.:. .: :: .
NP_001 PDQERSLSAYPVG-EEAAEDGRSSHHRHRRGQETVSSEL----KKPLGPASFNLSEYFRQ
210 220 230 240 250
290 300 310 320 330 340
pF1KE3 -----NQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNL
:.: :: :..:: :: ::.::.:: :.: :::: : :.. .:: :...::.
NP_001 FLLPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNI
260 270 280 290 300 310
350 360 370 380 390
pF1KE3 INQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR
: . .:.::::::::: :: :.::: :: .::: ::::: ::: .::::
NP_001 IYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR
320 330 340 350 360
>>XP_011541611 (OMIM: 601918) PREDICTED: growth/differen (366 aa)
initn: 541 init1: 462 opt: 462 Z-score: 561.9 bits: 112.7 E(85289): 1.5e-24
Smith-Waterman score: 531; 34.0% identity (54.1% similar) in 379 aa overlap (70-392:1-366)
40 50 60 70 80 90
pF1KE3 PTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVK
: .::. : ..: :. ::. . :::
XP_011 MKKLYKTYATKEGIPKSNRSHLYNTVRLFT
10 20 30
100 110 120 130 140
pF1KE3 PLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQ-LTRFNLS---------
: : :. . :. :. : . :..: : :.: .: :. . .:..
XP_011 PCTR----HKQAPGDQVTGI-LPSVELLFNLDRITTV-EHLLKSVLLYNINNSVSFSSAV
40 50 60 70 80
150 160 170 180 190 200
pF1KE3 ---CHV---EPWVQKNPTNHFPSSEGDSSKPSL-MSNAWKEMDITQLVQQRFWNNKGHRI
:.. :: .. .. : : .:. . .. : ..:.:.:.: .::
XP_011 KCVCNLMIKEPKSSSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIH
90 100 110 120 130 140
210 220 230 240
pF1KE3 LRLRFMC---QQQKDSGGLELWHGTSSLDIAFLLLYFNDT-----------HKSIRKAK-
. . : : : .. :. :.. : : :.::.::: : . : ..
XP_011 MSINFTCMKDQLEHPSAQNGLFNMT--LVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQG
150 160 170 180 190 200
250 260 270 280
pF1KE3 --------FLPRGMEEFME--RESLLRRTRQADGISAEVTASSSKHSGPEN---------
: : :: : : : :. : . .:.:. .: :: .
XP_011 PDQERSLSAYPVG-EEAAEDGRSSHHRHRRGQETVSSEL----KKPLGPASFNLSEYFRQ
210 220 230 240 250
290 300 310 320 330 340
pF1KE3 -----NQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNL
:.: :: :..:: :: ::.::.:: :.: :::: : :.. .:: :...::.
XP_011 FLLPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNI
260 270 280 290 300 310
350 360 370 380 390
pF1KE3 INQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR
: . .:.::::::::: :: :.::: :: .::: ::::: ::: .::::
XP_011 IYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR
320 330 340 350 360
>>NP_001275753 (OMIM: 601918) growth/differentiation fac (366 aa)
initn: 541 init1: 462 opt: 462 Z-score: 561.9 bits: 112.7 E(85289): 1.5e-24
Smith-Waterman score: 531; 34.0% identity (54.1% similar) in 379 aa overlap (70-392:1-366)
40 50 60 70 80 90
pF1KE3 PTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVK
: .::. : ..: :. ::. . :::
NP_001 MKKLYKTYATKEGIPKSNRSHLYNTVRLFT
10 20 30
100 110 120 130 140
pF1KE3 PLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQ-LTRFNLS---------
: : :. . :. :. : . :..: : :.: .: :. . .:..
NP_001 PCTR----HKQAPGDQVTGI-LPSVELLFNLDRITTV-EHLLKSVLLYNINNSVSFSSAV
40 50 60 70 80
150 160 170 180 190 200
pF1KE3 ---CHV---EPWVQKNPTNHFPSSEGDSSKPSL-MSNAWKEMDITQLVQQRFWNNKGHRI
:.. :: .. .. : : .:. . .. : ..:.:.:.: .::
NP_001 KCVCNLMIKEPKSSSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIH
90 100 110 120 130 140
210 220 230 240
pF1KE3 LRLRFMC---QQQKDSGGLELWHGTSSLDIAFLLLYFNDT-----------HKSIRKAK-
. . : : : .. :. :.. : : :.::.::: : . : ..
NP_001 MSINFTCMKDQLEHPSAQNGLFNMT--LVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQG
150 160 170 180 190 200
250 260 270 280
pF1KE3 --------FLPRGMEEFME--RESLLRRTRQADGISAEVTASSSKHSGPEN---------
: : :: : : : :. : . .:.:. .: :: .
NP_001 PDQERSLSAYPVG-EEAAEDGRSSHHRHRRGQETVSSEL----KKPLGPASFNLSEYFRQ
210 220 230 240 250
290 300 310 320 330 340
pF1KE3 -----NQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNL
:.: :: :..:: :: ::.::.:: :.: :::: : :.. .:: :...::.
NP_001 FLLPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNI
260 270 280 290 300 310
350 360 370 380 390
pF1KE3 INQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR
: . .:.::::::::: :: :.::: :: .::: ::::: ::: .::::
NP_001 IYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR
320 330 340 350 360
>>XP_005272014 (OMIM: 601918) PREDICTED: growth/differen (366 aa)
initn: 541 init1: 462 opt: 462 Z-score: 561.9 bits: 112.7 E(85289): 1.5e-24
Smith-Waterman score: 531; 34.0% identity (54.1% similar) in 379 aa overlap (70-392:1-366)
40 50 60 70 80 90
pF1KE3 PTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVK
: .::. : ..: :. ::. . :::
XP_005 MKKLYKTYATKEGIPKSNRSHLYNTVRLFT
10 20 30
100 110 120 130 140
pF1KE3 PLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQ-LTRFNLS---------
: : :. . :. :. : . :..: : :.: .: :. . .:..
XP_005 PCTR----HKQAPGDQVTGI-LPSVELLFNLDRITTV-EHLLKSVLLYNINNSVSFSSAV
40 50 60 70 80
150 160 170 180 190 200
pF1KE3 ---CHV---EPWVQKNPTNHFPSSEGDSSKPSL-MSNAWKEMDITQLVQQRFWNNKGHRI
:.. :: .. .. : : .:. . .. : ..:.:.:.: .::
XP_005 KCVCNLMIKEPKSSSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIH
90 100 110 120 130 140
210 220 230 240
pF1KE3 LRLRFMC---QQQKDSGGLELWHGTSSLDIAFLLLYFNDT-----------HKSIRKAK-
. . : : : .. :. :.. : : :.::.::: : . : ..
XP_005 MSINFTCMKDQLEHPSAQNGLFNMT--LVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQG
150 160 170 180 190 200
250 260 270 280
pF1KE3 --------FLPRGMEEFME--RESLLRRTRQADGISAEVTASSSKHSGPEN---------
: : :: : : : :. : . .:.:. .: :: .
XP_005 PDQERSLSAYPVG-EEAAEDGRSSHHRHRRGQETVSSEL----KKPLGPASFNLSEYFRQ
210 220 230 240 250
290 300 310 320 330 340
pF1KE3 -----NQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNL
:.: :: :..:: :: ::.::.:: :.: :::: : :.. .:: :...::.
XP_005 FLLPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNI
260 270 280 290 300 310
350 360 370 380 390
pF1KE3 INQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR
: . .:.::::::::: :: :.::: :: .::: ::::: ::: .::::
XP_005 IYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR
320 330 340 350 360
>>XP_011541612 (OMIM: 601918) PREDICTED: growth/differen (366 aa)
initn: 541 init1: 462 opt: 462 Z-score: 561.9 bits: 112.7 E(85289): 1.5e-24
Smith-Waterman score: 531; 34.0% identity (54.1% similar) in 379 aa overlap (70-392:1-366)
40 50 60 70 80 90
pF1KE3 PTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVK
: .::. : ..: :. ::. . :::
XP_011 MKKLYKTYATKEGIPKSNRSHLYNTVRLFT
10 20 30
100 110 120 130 140
pF1KE3 PLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQ-LTRFNLS---------
: : :. . :. :. : . :..: : :.: .: :. . .:..
XP_011 PCTR----HKQAPGDQVTGI-LPSVELLFNLDRITTV-EHLLKSVLLYNINNSVSFSSAV
40 50 60 70 80
150 160 170 180 190 200
pF1KE3 ---CHV---EPWVQKNPTNHFPSSEGDSSKPSL-MSNAWKEMDITQLVQQRFWNNKGHRI
:.. :: .. .. : : .:. . .. : ..:.:.:.: .::
XP_011 KCVCNLMIKEPKSSSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIH
90 100 110 120 130 140
210 220 230 240
pF1KE3 LRLRFMC---QQQKDSGGLELWHGTSSLDIAFLLLYFNDT-----------HKSIRKAK-
. . : : : .. :. :.. : : :.::.::: : . : ..
XP_011 MSINFTCMKDQLEHPSAQNGLFNMT--LVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQG
150 160 170 180 190 200
250 260 270 280
pF1KE3 --------FLPRGMEEFME--RESLLRRTRQADGISAEVTASSSKHSGPEN---------
: : :: : : : :. : . .:.:. .: :: .
XP_011 PDQERSLSAYPVG-EEAAEDGRSSHHRHRRGQETVSSEL----KKPLGPASFNLSEYFRQ
210 220 230 240 250
290 300 310 320 330 340
pF1KE3 -----NQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNL
:.: :: :..:: :: ::.::.:: :.: :::: : :.. .:: :...::.
XP_011 FLLPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNI
260 270 280 290 300 310
350 360 370 380 390
pF1KE3 INQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR
: . .:.::::::::: :: :.::: :: .::: ::::: ::: .::::
XP_011 IYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR
320 330 340 350 360
>>NP_001275756 (OMIM: 601918) growth/differentiation fac (366 aa)
initn: 541 init1: 462 opt: 462 Z-score: 561.9 bits: 112.7 E(85289): 1.5e-24
Smith-Waterman score: 531; 34.0% identity (54.1% similar) in 379 aa overlap (70-392:1-366)
40 50 60 70 80 90
pF1KE3 PTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVK
: .::. : ..: :. ::. . :::
NP_001 MKKLYKTYATKEGIPKSNRSHLYNTVRLFT
10 20 30
100 110 120 130 140
pF1KE3 PLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQ-LTRFNLS---------
: : :. . :. :. : . :..: : :.: .: :. . .:..
NP_001 PCTR----HKQAPGDQVTGI-LPSVELLFNLDRITTV-EHLLKSVLLYNINNSVSFSSAV
40 50 60 70 80
150 160 170 180 190 200
pF1KE3 ---CHV---EPWVQKNPTNHFPSSEGDSSKPSL-MSNAWKEMDITQLVQQRFWNNKGHRI
:.. :: .. .. : : .:. . .. : ..:.:.:.: .::
NP_001 KCVCNLMIKEPKSSSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIH
90 100 110 120 130 140
210 220 230 240
pF1KE3 LRLRFMC---QQQKDSGGLELWHGTSSLDIAFLLLYFNDT-----------HKSIRKAK-
. . : : : .. :. :.. : : :.::.::: : . : ..
NP_001 MSINFTCMKDQLEHPSAQNGLFNMT--LVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQG
150 160 170 180 190 200
250 260 270 280
pF1KE3 --------FLPRGMEEFME--RESLLRRTRQADGISAEVTASSSKHSGPEN---------
: : :: : : : :. : . .:.:. .: :: .
NP_001 PDQERSLSAYPVG-EEAAEDGRSSHHRHRRGQETVSSEL----KKPLGPASFNLSEYFRQ
210 220 230 240 250
290 300 310 320 330 340
pF1KE3 -----NQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNL
:.: :: :..:: :: ::.::.:: :.: :::: : :.. .:: :...::.
NP_001 FLLPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNI
260 270 280 290 300 310
350 360 370 380 390
pF1KE3 INQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR
: . .:.::::::::: :: :.::: :: .::: ::::: ::: .::::
NP_001 IYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR
320 330 340 350 360
>>NP_001275754 (OMIM: 601918) growth/differentiation fac (366 aa)
initn: 541 init1: 462 opt: 462 Z-score: 561.9 bits: 112.7 E(85289): 1.5e-24
Smith-Waterman score: 531; 34.0% identity (54.1% similar) in 379 aa overlap (70-392:1-366)
40 50 60 70 80 90
pF1KE3 PTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVK
: .::. : ..: :. ::. . :::
NP_001 MKKLYKTYATKEGIPKSNRSHLYNTVRLFT
10 20 30
100 110 120 130 140
pF1KE3 PLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQ-LTRFNLS---------
: : :. . :. :. : . :..: : :.: .: :. . .:..
NP_001 PCTR----HKQAPGDQVTGI-LPSVELLFNLDRITTV-EHLLKSVLLYNINNSVSFSSAV
40 50 60 70 80
150 160 170 180 190 200
pF1KE3 ---CHV---EPWVQKNPTNHFPSSEGDSSKPSL-MSNAWKEMDITQLVQQRFWNNKGHRI
:.. :: .. .. : : .:. . .. : ..:.:.:.: .::
NP_001 KCVCNLMIKEPKSSSRTLGRAPYSFTFNSQFEFGKKHKWIQIDVTSLLQPLVASNKRSIH
90 100 110 120 130 140
210 220 230 240
pF1KE3 LRLRFMC---QQQKDSGGLELWHGTSSLDIAFLLLYFNDT-----------HKSIRKAK-
. . : : : .. :. :.. : : :.::.::: : . : ..
NP_001 MSINFTCMKDQLEHPSAQNGLFNMT--LVSPSLILYLNDTSAQAYHSWYSLHYKRRPSQG
150 160 170 180 190 200
250 260 270 280
pF1KE3 --------FLPRGMEEFME--RESLLRRTRQADGISAEVTASSSKHSGPEN---------
: : :: : : : :. : . .:.:. .: :: .
NP_001 PDQERSLSAYPVG-EEAAEDGRSSHHRHRRGQETVSSEL----KKPLGPASFNLSEYFRQ
210 220 230 240 250
290 300 310 320 330 340
pF1KE3 -----NQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNL
:.: :: :..:: :: ::.::.:: :.: :::: : :.. .:: :...::.
NP_001 FLLPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNI
260 270 280 290 300 310
350 360 370 380 390
pF1KE3 INQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR
: . .:.::::::::: :: :.::: :: .::: ::::: ::: .::::
NP_001 IYEKLDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR
320 330 340 350 360
392 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 02:22:22 2016 done: Sun Nov 6 02:22:24 2016
Total Scan time: 8.500 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]