Result of FASTA (ccds) for
pFN21AE5265
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5265, 190 aa
1>>>pF1KE5265 190 - 190 aa - 190 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3237+/-0.000994; mu= 12.3328+/- 0.060
mean_var=59.7325+/-11.923, 0's: 0 Z-trim(103.0): 56 B-trim: 69 in 1/48
Lambda= 0.165947
statistics sampled from 7131 (7188) to 7131 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.594), E-opt: 0.2 (0.221), width: 16
Scan time: 1.490
The best scores are: opt bits E(32554)
CCDS14264.1 DUSP21 gene_id:63904|Hs108|chrX ( 190) 1236 304.4 2.7e-83
CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 ( 188) 902 224.5 3.1e-59
CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 ( 198) 613 155.3 2.2e-38
CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 ( 367) 322 85.7 3.6e-17
CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 ( 303) 296 79.5 2.3e-15
CCDS6072.1 DUSP4 gene_id:1846|Hs108|chr8 ( 394) 296 79.5 2.9e-15
CCDS1528.1 DUSP10 gene_id:11221|Hs108|chr1 ( 482) 290 78.1 9.2e-15
CCDS7566.1 DUSP5 gene_id:1847|Hs108|chr10 ( 384) 284 76.6 2e-14
CCDS2016.1 DUSP2 gene_id:1844|Hs108|chr2 ( 314) 282 76.1 2.4e-14
CCDS8650.1 DUSP16 gene_id:80824|Hs108|chr12 ( 665) 282 76.2 4.6e-14
CCDS33418.1 DUSP28 gene_id:285193|Hs108|chr2 ( 176) 274 74.1 5.4e-14
CCDS7724.1 DUSP8 gene_id:1850|Hs108|chr11 ( 625) 276 74.8 1.2e-13
CCDS13193.1 DUSP15 gene_id:128853|Hs108|chr20 ( 235) 267 72.5 2.2e-13
CCDS2289.1 DUSP19 gene_id:142679|Hs108|chr2 ( 217) 265 72.0 2.9e-13
CCDS82607.1 DUSP15 gene_id:128853|Hs108|chr20 ( 232) 263 71.5 4.3e-13
CCDS33766.2 DUSP7 gene_id:1849|Hs108|chr3 ( 419) 252 69.0 4.5e-12
CCDS7346.1 DUSP13 gene_id:51207|Hs108|chr10 ( 198) 248 67.9 4.5e-12
CCDS31224.1 DUSP13 gene_id:51207|Hs108|chr10 ( 248) 248 67.9 5.5e-12
CCDS82606.1 DUSP15 gene_id:128853|Hs108|chr20 ( 295) 248 68.0 6.4e-12
CCDS6092.1 DUSP26 gene_id:78986|Hs108|chr8 ( 211) 244 66.9 9.2e-12
CCDS4468.1 DUSP22 gene_id:56940|Hs108|chr6 ( 184) 242 66.4 1.1e-11
CCDS69035.1 DUSP22 gene_id:56940|Hs108|chr6 ( 205) 242 66.5 1.2e-11
CCDS14724.1 DUSP9 gene_id:1852|Hs108|chrX ( 384) 237 65.4 5e-11
CCDS53542.1 DUSP13 gene_id:51207|Hs108|chr10 ( 188) 230 63.6 8.5e-11
CCDS8157.1 SSH3 gene_id:54961|Hs108|chr11 ( 659) 236 65.2 9.5e-11
>>CCDS14264.1 DUSP21 gene_id:63904|Hs108|chrX (190 aa)
initn: 1236 init1: 1236 opt: 1236 Z-score: 1608.9 bits: 304.4 E(32554): 2.7e-83
Smith-Waterman score: 1236; 100.0% identity (100.0% similar) in 190 aa overlap (1-190:1-190)
10 20 30 40 50 60
pF1KE5 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIY
130 140 150 160 170 180
190
pF1KE5 EKDLRMMISM
::::::::::
CCDS14 EKDLRMMISM
190
>>CCDS13883.1 DUSP18 gene_id:150290|Hs108|chr22 (188 aa)
initn: 918 init1: 894 opt: 902 Z-score: 1176.8 bits: 224.5 E(32554): 3.1e-59
Smith-Waterman score: 902; 68.9% identity (91.1% similar) in 190 aa overlap (1-190:1-188)
10 20 30 40 50 60
pF1KE5 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN
::: . .: . .:::. ..::::.::..:::::::.::.::::.:: ..:.::::::
CCDS13 MTAPSCAFPVQ--FRQPSVSGLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVN
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY
...: :::..:::.:. .::: :::::::: ::...:.:::::::: :::::::.:::::
CCDS13 TLYEDIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE5 LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIY
:::::.:::::::::::: :::::::.:::::::.:::.::..:::.:..:::: :::::
CCDS13 LMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQLFGKNTVHMVSSPVGMIPDIY
120 130 140 150 160 170
190
pF1KE5 EKDLRMMISM
::..:.:: .
CCDS13 EKEVRLMIPL
180
>>CCDS11320.1 DUSP14 gene_id:11072|Hs108|chr17 (198 aa)
initn: 627 init1: 606 opt: 613 Z-score: 802.5 bits: 155.3 E(32554): 2.2e-38
Smith-Waterman score: 613; 48.0% identity (81.7% similar) in 175 aa overlap (14-188:19-193)
10 20 30 40 50
pF1KE5 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNAS
... .: ...::: ::::. : .:... ::.. :: ::::.
CCDS11 MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNAT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 VEVVNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSAS
.:. : . ..:.:::..: . . .:: .:: ::... ..: ::.:: :::::::.
CCDS11 IEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSAT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 LCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGN
::.:::::.:.. ::.:..:.:.:::.:::: :::.:::.:: .::...::.:...: :
CCDS11 LCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGI
130 140 150 160 170 180
180 190
pF1KE5 IPDIYEKDLRMMISM
.::.:::. : ..
CCDS11 VPDVYEKESRHLMPYWGI
190
>>CCDS4380.1 DUSP1 gene_id:1843|Hs108|chr5 (367 aa)
initn: 344 init1: 321 opt: 322 Z-score: 421.8 bits: 85.7 E(32554): 3.6e-17
Smith-Waterman score: 322; 36.4% identity (68.9% similar) in 151 aa overlap (29-178:181-330)
10 20 30 40 50
pF1KE5 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEV
:.:... :. : .:.. :::..:.:..
CCDS43 TSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANC
160 170 180 190 200 210
60 70 80 90 100 110
pF1KE5 VNVFFEG-IQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLC
: ::: :: ..:: : . . . ..:. :.: .: ::...::.::.::::..:
CCDS43 PN-HFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATIC
220 230 240 250 260
120 130 140 150 160 170
pF1KE5 LAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIP
:::::. . ..: .: ..:.:: :: :: .: ::...: ... . .::. .
CCDS43 LAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVL
270 280 290 300 310 320
180 190
pF1KE5 DIYEKDLRMMISM
:
CCDS43 DRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC
330 340 350 360
>>CCDS6073.1 DUSP4 gene_id:1846|Hs108|chr8 (303 aa)
initn: 280 init1: 280 opt: 296 Z-score: 389.5 bits: 79.5 E(32554): 2.3e-15
Smith-Waterman score: 296; 36.1% identity (66.0% similar) in 147 aa overlap (29-174:112-257)
10 20 30 40 50
pF1KE5 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEV
:.:... : . .:.. :::..:.: .
CCDS60 PSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDC
90 100 110 120 130 140
60 70 80 90 100 110
pF1KE5 VNVFFEG-IQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLC
: ::: :: .:: : . . . ..: . : .. .::.:.::.::.::::..:
CCDS60 PN-HFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATIC
150 160 170 180 190 200
120 130 140 150 160 170
pF1KE5 LAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIP
::::: . . : .: ..:.:: :: :: .: ::...: ... .. . :: :
CCDS60 LAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLR
210 220 230 240 250 260
180 190
pF1KE5 DIYEKDLRMMISM
CCDS60 ERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC
270 280 290 300
>>CCDS6072.1 DUSP4 gene_id:1846|Hs108|chr8 (394 aa)
initn: 280 init1: 280 opt: 296 Z-score: 387.6 bits: 79.5 E(32554): 2.9e-15
Smith-Waterman score: 296; 36.1% identity (66.0% similar) in 147 aa overlap (29-174:203-348)
10 20 30 40 50
pF1KE5 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEV
:.:... : . .:.. :::..:.: .
CCDS60 PSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDC
180 190 200 210 220 230
60 70 80 90 100 110
pF1KE5 VNVFFEG-IQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLC
: ::: :: .:: : . . . ..: . : .. .::.:.::.::.::::..:
CCDS60 PN-HFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATIC
240 250 260 270 280 290
120 130 140 150 160 170
pF1KE5 LAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIP
::::: . . : .: ..:.:: :: :: .: ::...: ... .. . :: :
CCDS60 LAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLR
300 310 320 330 340 350
180 190
pF1KE5 DIYEKDLRMMISM
CCDS60 ERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC
360 370 380 390
>>CCDS1528.1 DUSP10 gene_id:11221|Hs108|chr1 (482 aa)
initn: 235 init1: 216 opt: 290 Z-score: 378.5 bits: 78.1 E(32554): 9.2e-15
Smith-Waterman score: 290; 31.9% identity (63.2% similar) in 182 aa overlap (3-179:300-481)
10 20
pF1KE5 MTASASSFSSSQGVQQ-PSIYS--FSQITRSL
:::.: : . :.: . .. : :
CCDS15 KGGLSSFKQNHENLCDNSLQLQECREVGGGASAASSLLPQPIPTTPDIENAELTPILPFL
270 280 290 300 310 320
30 40 50 60 70 80
pF1KE5 FLSNGVAANDKLLLSSNRITAIVNASVEVVNVFFE-GI-QYIKVPVTDARDSRLYDFFDP
::.: :.: .. : ..:..... .: :. .: ..:.::. . : ..:.
CCDS15 FLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEE
330 340 350 360 370 380
90 100 110 120 130 140
pF1KE5 IADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNN
..:. . :.::.:::::::.. .:::::. :.. ::. ..:..:::: ::
CCDS15 AFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNL
390 400 410 420 430 440
150 160 170 180 190
pF1KE5 GFWEQLINYEFKLFNNNTVRMINSPVGNIPDIYEKDLRMMISM
.: ::...: : :. : :... . .. .
CCDS15 NFMGQLLEFEEDLNNGVTPRILTPKLMGVETVV
450 460 470 480
>>CCDS7566.1 DUSP5 gene_id:1847|Hs108|chr10 (384 aa)
initn: 301 init1: 269 opt: 284 Z-score: 372.3 bits: 76.6 E(32554): 2e-14
Smith-Waterman score: 284; 33.1% identity (69.2% similar) in 133 aa overlap (29-161:186-318)
10 20 30 40 50
pF1KE5 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEV
:.:... :. .:.. .:::..:.: ..
CCDS75 ALISQCGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRT
160 170 180 190 200 210
60 70 80 90 100 110
pF1KE5 VNVFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCL
.. ..: .:: :.. . . . :. :.: . . :..:.:: ::.::: ..:.
CCDS75 SEACATHLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICM
220 230 240 250 260 270
120 130 140 150 160 170
pF1KE5 AYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPD
::::: ... : .: . :.:: .. :: :: ::..:: ...
CCDS75 AYLMKTKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAG
280 290 300 310 320 330
180 190
pF1KE5 IYEKDLRMMISM
CCDS75 SSLIGHLQTLSPDMQGAYCTFPASVLAPVPTHSTVSELSRSPVATATSC
340 350 360 370 380
>>CCDS2016.1 DUSP2 gene_id:1844|Hs108|chr2 (314 aa)
initn: 276 init1: 276 opt: 282 Z-score: 371.1 bits: 76.1 E(32554): 2.4e-14
Smith-Waterman score: 282; 36.0% identity (66.9% similar) in 139 aa overlap (24-161:175-312)
10 20 30 40 50
pF1KE5 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVN
.: :::.. ..: :.. :::..:
CCDS20 EAPAPALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLN
150 160 170 180 190 200
60 70 80 90 100 110
pF1KE5 ASVEVVNVFFEGI-QYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSR
.:. : :::. .: ..:: : . .. .:. .: . ::.:.::.::.::
CCDS20 VSASCPN-HFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISR
210 220 230 240 250 260
120 130 140 150 160 170
pF1KE5 SASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSP
::..::::::. . . : .: ..:.:: .: :: .: ::...: ...
CCDS20 SATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH
270 280 290 300 310
180 190
pF1KE5 VGNIPDIYEKDLRMMISM
>>CCDS8650.1 DUSP16 gene_id:80824|Hs108|chr12 (665 aa)
initn: 248 init1: 248 opt: 282 Z-score: 365.9 bits: 76.2 E(32554): 4.6e-14
Smith-Waterman score: 282; 34.8% identity (67.4% similar) in 141 aa overlap (23-162:160-300)
10 20 30 40 50
pF1KE5 MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIV
..: .:.:. . .: :...: : ..
CCDS86 RCFPGLCEGKSTLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVL
130 140 150 160 170 180
60 70 80 90 100 110
pF1KE5 NASVEVVNV-FFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVS
::: . :. ....:::.:. .. ..: .:.:. .: .:.::.::.:
CCDS86 NASNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGIS
190 200 210 220 230 240
120 130 140 150 160 170
pF1KE5 RSASLCLAYLMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINS
:::.. .::.:: .::: .:. ..: .:: : :: .: ::..:: :. :
CCDS86 RSATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGASGPKS
250 260 270 280 290 300
180 190
pF1KE5 PVGNIPDIYEKDLRMMISM
CCDS86 KLKLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPS
310 320 330 340 350 360
190 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:00:20 2016 done: Mon Nov 7 23:00:20 2016
Total Scan time: 1.490 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]