FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE4080, 425 aa
  1>>>pF1KE4080 425 - 425 aa - 425 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.8784+/-0.000915; mu= -1.8703+/- 0.055
 mean_var=269.7348+/-55.553, 0's: 0 Z-trim(115.5): 11  B-trim: 115 in 2/51
 Lambda= 0.078092
 statistics sampled from 16060 (16069) to 16060 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.795), E-opt: 0.2 (0.494), width:  16
 Scan time:  3.410

The best scores are:                                      opt bits E(32554)
CCDS14205.1 ZNF645 gene_id:158506|Hs108|chrX       ( 425) 3037 354.9 8.3e-98
CCDS64754.1 CBLL1 gene_id:79872|Hs108|chr7         ( 490) 1319 161.4 1.7e-39
CCDS5747.1 CBLL1 gene_id:79872|Hs108|chr7          ( 491) 1316 161.1 2.2e-39


>>CCDS14205.1 ZNF645 gene_id:158506|Hs108|chrX            (425 aa)
 initn: 3037 init1: 3037 opt: 3037  Z-score: 1869.4  bits: 354.9 E(32554): 8.3e-98
Smith-Waterman score: 3037; 99.8% identity (100.0% similar) in 425 aa overlap (1-425:1-425)

               10        20        30        40        50        60
pF1KE4 MNKMPAGEQECEYNKEGKYYSKGVKLVRKKKKIPGYRWGDIKINIIGEKDDLPIHFCDKC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MNKMPAGEQECEYNKEGKYYSKGVKLVRKKKKIPGYRWGDIKINIIGEKDDLPIHFCDKC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE4 DLPIKIYGRIIPCKHAFCYHCANLYDKVGYKVCPRCRYPVLRIEAHKRGSVFMCSIVQQC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 DLPIKIYGRIIPCKHAFCYHCANLYDKVGYKVCPRCRYPVLRIEAHKRGSVFMCSIVQQC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE4 KRTYLSQKSLQAHIKRRHKRARKQVTSASLEKVRPHIAPPQTEISDIPKRLQDRDHLSYI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 KRTYLSQKSLQAHIKRRHKRARKQVTSASLEKVRPHIAPPQTEISDIPKRLQDRDHLSYI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE4 PPEQHTMVSLPSVQHMLQEQHNQPHKDIQAPPPELSLSLPFPIQWETVSIFTRKHGNLTV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 PPEQHTMVSLPSVQHMLQEQHNQPHKDIQAPPPELSLSLPFPIQWETVSIFTRKHGNLTV
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE4 DHIQNNSDSGVKKPTPPDYYPECQSQPAVSSPHHIIPQKQHYAPPPSPSSPVNHQMPYPP
       ::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 DHIQNNSDSGAKKPTPPDYYPECQSQPAVSSPHHIIPQKQHYAPPPSPSSPVNHQMPYPP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE4 QDVVTPNSVRSQVPALTTTYDPSSGYIIVKVPPDMNSPPLRAPQSQNGNPSASEFASHHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 QDVVTPNSVRSQVPALTTTYDPSSGYIIVKVPPDMNSPPLRAPQSQNGNPSASEFASHHY
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE4 NLNILPQFTENQETLSPQFTQTDAMDHRRWPAWKRLSPCPPTRSPPPSTLHGRSHHSHQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 NLNILPQFTENQETLSPQFTQTDAMDHRRWPAWKRLSPCPPTRSPPPSTLHGRSHHSHQR
              370       380       390       400       410       420

            
pF1KE4 RHRRY
       :::::
CCDS14 RHRRY
            

>>CCDS64754.1 CBLL1 gene_id:79872|Hs108|chr7              (490 aa)
 initn: 1571 init1: 917 opt: 1319  Z-score: 822.5  bits: 161.4 E(32554): 1.7e-39
Smith-Waterman score: 1562; 52.7% identity (71.7% similar) in 446 aa overlap (1-425:48-488)

                                                 10        20      
pF1KE4                               MNKMPA----GEQECEYNKEGKYYSKGVKL
                                     .:.:::    :..  .::.: .:  :: .:
CCDS64 GGLDVRRRIPIKLISKQANKAKPAPRTQRTINRMPAKAPPGDEGFDYNEEERYDCKGGEL
        20        30        40        50        60        70       

         30        40        50        60        70        80      
pF1KE4 VRKKKKIPGYRWGDIKINIIGEKDDLPIHFCDKCDLPIKIYGRIIPCKHAFCYHCANLYD
         .....::. . :..:::.::::: :.:::::: ::::::::.:::::.::: :: :..
CCDS64 FANQRRFPGHLFWDFQINILGEKDDTPVHFCDKCGLPIKIYGRMIPCKHVFCYDCAILHE
        80        90       100       110       120       130       

         90       100       110       120       130       140      
pF1KE4 KVGYKVCPRCRYPVLRIEAHKRGSVFMCSIVQQCKRTYLSQKSLQAHIKRRHKRARKQVT
       : : :.:: :  :: :::   :::.::::::: ::::::::..:::::..:: :: : ::
CCDS64 KKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPVT
       140       150       160       170       180       190       

        150       160       170          180       190       200   
pF1KE4 SASLEKVRPHIAPPQTEISDIPKRL---QDRDHLSYIPPEQHTMVSLPSVQHMLQEQHNQ
        ::::.:.: :::: :::   :.:.    :. :.:.:::.:: :.  : .::. .:..::
CCDS64 RASLENVHPPIAPPPTEI---PERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYNQ
       200       210          220       230       240       250    

           210       220         230       240       250           
pF1KE4 PHKDIQAPPPELSLSLPFP--IQWETVSIFTRKHGNLTVDHIQNNSDSGVKKPTPP----
       ::.::.::: :::.. : :  .. ::  : ::::.:: .  ::..:.::...: ::    
CCDS64 PHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAP
          260       270       280       290       300       310    

        260       270       280       290       300       310      
pF1KE4 -DYYPECQSQPAVSSPHHIIPQKQHYAPPPSPSSPVNHQMPYPPQDVVTPNSVRSQVPA-
         ..:: :.::.:: ::::.: .::::::: :  :..: ::.::: . ::. : ::.:  
CCDS64 AHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPP
          320       330       340       350       360       370    

             320       330       340       350       360       370 
pF1KE4 -LTTT---YDPSSGYIIVKVPPDMNSPPLRAPQSQNGNPSASEFASHHYNLNILPQFTEN
        .:..     :  :.::...:: :: ::   :  :.:.: ..    :::: : ::::::.
CCDS64 PMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTED
          380       390       400       410       420       430    

             380       390       400         410       420       
pF1KE4 QETLSPQFTQTDAMDHRRWPAWKRLSPCPPTRSPPPST--LHGRSHHSHQRRHRRY  
       : :::: :::  .:.   :::  :  : ::  . :::   : :  ::  : :.: :  
CCDS64 QGTLSPPFTQPGGMSPGIWPA-PRGPPPPPRLQGPPSQTPLPG-PHHPDQTRYRPYYQ
          440       450        460       470        480       490

>>CCDS5747.1 CBLL1 gene_id:79872|Hs108|chr7               (491 aa)
 initn: 1571 init1: 917 opt: 1316  Z-score: 820.7  bits: 161.1 E(32554): 2.2e-39
Smith-Waterman score: 1559; 52.8% identity (71.8% similar) in 447 aa overlap (1-425:48-489)

                                                 10         20     
pF1KE4                               MNKMPA----GEQE-CEYNKEGKYYSKGVK
                                     .:.:::    :..:  .::.: .:  :: .
CCDS57 GGLDVRRRIPIKLISKQANKAKPAPRTQRTINRMPAKAPPGDEEGFDYNEEERYDCKGGE
        20        30        40        50        60        70       

          30        40        50        60        70        80     
pF1KE4 LVRKKKKIPGYRWGDIKINIIGEKDDLPIHFCDKCDLPIKIYGRIIPCKHAFCYHCANLY
       :  .....::. . :..:::.::::: :.:::::: ::::::::.:::::.::: :: :.
CCDS57 LFANQRRFPGHLFWDFQINILGEKDDTPVHFCDKCGLPIKIYGRMIPCKHVFCYDCAILH
        80        90       100       110       120       130       

          90       100       110       120       130       140     
pF1KE4 DKVGYKVCPRCRYPVLRIEAHKRGSVFMCSIVQQCKRTYLSQKSLQAHIKRRHKRARKQV
       .: : :.:: :  :: :::   :::.::::::: ::::::::..:::::..:: :: : :
CCDS57 EKKGDKMCPGCSDPVQRIEQCTRGSLFMCSIVQGCKRTYLSQRDLQAHINHRHMRAGKPV
       140       150       160       170       180       190       

         150       160       170          180       190       200  
pF1KE4 TSASLEKVRPHIAPPQTEISDIPKRL---QDRDHLSYIPPEQHTMVSLPSVQHMLQEQHN
       : ::::.:.: :::: :::   :.:.    :. :.:.:::.:: :.  : .::. .:..:
CCDS57 TRASLENVHPPIAPPPTEI---PERFIMPPDKHHMSHIPPKQHIMMPPPPLQHVPHEHYN
       200       210          220       230       240       250    

            210       220         230       240       250          
pF1KE4 QPHKDIQAPPPELSLSLPFP--IQWETVSIFTRKHGNLTVDHIQNNSDSGVKKPTPP---
       :::.::.::: :::.. : :  .. ::  : ::::.:: .  ::..:.::...: ::   
CCDS57 QPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPA
          260       270       280       290       300       310    

         260       270       280       290       300       310     
pF1KE4 --DYYPECQSQPAVSSPHHIIPQKQHYAPPPSPSSPVNHQMPYPPQDVVTPNSVRSQVPA
          ..:: :.::.:: ::::.: .::::::: :  :..: ::.::: . ::. : ::.: 
CCDS57 PAHHHPEYQGQPVVSHPHHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPP
          320       330       340       350       360       370    

              320       330       340       350       360       370
pF1KE4 --LTTT---YDPSSGYIIVKVPPDMNSPPLRAPQSQNGNPSASEFASHHYNLNILPQFTE
         .:..     :  :.::...:: :: ::   :  :.:.: ..    :::: : ::::::
CCDS57 PPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTE
          380       390       400       410       420       430    

              380       390       400         410       420       
pF1KE4 NQETLSPQFTQTDAMDHRRWPAWKRLSPCPPTRSPPPST--LHGRSHHSHQRRHRRY  
       .: :::: :::  .:.   :::  :  : ::  . :::   : :  ::  : :.: :  
CCDS57 DQGTLSPPFTQPGGMSPGIWPA-PRGPPPPPRLQGPPSQTPLPG-PHHPDQTRYRPYYQ
          440       450        460       470        480       490 




425 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 16:23:21 2016 done: Mon Nov  7 16:23:22 2016
 Total Scan time:  3.410 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]