Result of FASTA (omim) for
pFN21AE5636
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5636, 482 aa
1>>>pF1KE5636 482 - 482 aa - 482 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.9506+/-0.000522; mu= -16.1123+/- 0.033
mean_var=585.3470+/-120.848, 0's: 0 Z-trim(122.0): 62 B-trim: 940 in 1/57
Lambda= 0.053011
statistics sampled from 39375 (39451) to 39375 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.463), width: 16
Scan time: 8.810
The best scores are: opt bits E(85289)
NP_005080 (OMIM: 300028) U2 small nuclear ribonucl ( 482) 3302 267.4 6.3e-71
XP_016885370 (OMIM: 300028) PREDICTED: U2 small nu ( 486) 3216 260.8 6e-69
XP_011543891 (OMIM: 300028) PREDICTED: U2 small nu ( 460) 2931 239.0 2.1e-62
XP_011543892 (OMIM: 300028) PREDICTED: U2 small nu ( 348) 2331 193.0 1.1e-48
XP_005274654 (OMIM: 300028) PREDICTED: U2 small nu ( 348) 2331 193.0 1.1e-48
XP_016885372 (OMIM: 300028) PREDICTED: U2 small nu ( 348) 2331 193.0 1.1e-48
XP_016885371 (OMIM: 300028) PREDICTED: U2 small nu ( 348) 2331 193.0 1.1e-48
NP_001020374 (OMIM: 191317) splicing factor U2AF 3 ( 240) 460 49.7 1e-05
NP_006749 (OMIM: 191317) splicing factor U2AF 35 k ( 240) 444 48.5 2.4e-05
>>NP_005080 (OMIM: 300028) U2 small nuclear ribonucleopr (482 aa)
initn: 3302 init1: 3302 opt: 3302 Z-score: 1394.4 bits: 267.4 E(85289): 6.3e-71
Smith-Waterman score: 3302; 100.0% identity (100.0% similar) in 482 aa overlap (1-482:1-482)
10 20 30 40 50 60
pF1KE5 MAAPEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAAPEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKERE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 CRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 EDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 FCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 SERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 RSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPK
430 440 450 460 470 480
pF1KE5 SK
::
NP_005 SK
>>XP_016885370 (OMIM: 300028) PREDICTED: U2 small nuclea (486 aa)
initn: 3387 init1: 3216 opt: 3216 Z-score: 1358.8 bits: 260.8 E(85289): 6e-69
Smith-Waterman score: 3216; 100.0% identity (100.0% similar) in 469 aa overlap (1-469:1-469)
10 20 30 40 50 60
pF1KE5 MAAPEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAPEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 EKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKERE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 EEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 CRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 EDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 FCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 SERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 RSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPK
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSETGSCYVAQTG
430 440 450 460 470 480
pF1KE5 SK
XP_016 GQWLFT
>>XP_011543891 (OMIM: 300028) PREDICTED: U2 small nuclea (460 aa)
initn: 3102 init1: 2931 opt: 2931 Z-score: 1241.3 bits: 239.0 E(85289): 2.1e-62
Smith-Waterman score: 2931; 100.0% identity (100.0% similar) in 425 aa overlap (45-469:19-443)
20 30 40 50 60 70
pF1KE5 HKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEE
::::::::::::::::::::::::::::::
XP_011 MTFLCFLRALPASLVALCKEEEEDTFIEEQQLEEEKLLERERQRLHEE
10 20 30 40
80 90 100 110 120 130
pF1KE5 WLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEE
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE5 ALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFGDRCSRKHNFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFGDRCSRKHNFP
110 120 130 140 150 160
200 210 220 230 240 250
pF1KE5 TSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFYEDVLPEFKNVGKVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFYEDVLPEFKNVGKVI
170 180 190 200 210 220
260 270 280 290 300 310
pF1KE5 QFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCEFCPVTRWKMAICGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCEFCPVTRWKMAICGL
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE5 FEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKNSERRERMGHHDDYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKNSERRERMGHHDDYY
290 300 310 320 330 340
380 390 400 410 420 430
pF1KE5 SRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRS
350 360 370 380 390 400
440 450 460 470 480
pF1KE5 RGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPKSK
:::::::::::::::::::::::::::::::::::
XP_011 RGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSETGSCYVAQTGGQWLFT
410 420 430 440 450 460
>>XP_011543892 (OMIM: 300028) PREDICTED: U2 small nuclea (348 aa)
initn: 2502 init1: 2331 opt: 2331 Z-score: 994.8 bits: 193.0 E(85289): 1.1e-48
Smith-Waterman score: 2331; 100.0% identity (100.0% similar) in 331 aa overlap (139-469:1-331)
110 120 130 140 150 160
pF1KE5 EQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKD
::::::::::::::::::::::::::::::
XP_011 MLDQAENELENGTTWQNPEPPVDFRVMEKD
10 20 30
170 180 190 200 210 220
pF1KE5 RANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYS
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE5 EEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFN
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE5 GRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYL
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE5 SPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSH
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE5 KRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRR
280 290 300 310 320 330
470 480
pF1KE5 SGNRDRTVQSPKSK
:
XP_011 SETGSCYVAQTGGQWLFT
340
>>XP_005274654 (OMIM: 300028) PREDICTED: U2 small nuclea (348 aa)
initn: 2502 init1: 2331 opt: 2331 Z-score: 994.8 bits: 193.0 E(85289): 1.1e-48
Smith-Waterman score: 2331; 100.0% identity (100.0% similar) in 331 aa overlap (139-469:1-331)
110 120 130 140 150 160
pF1KE5 EQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKD
::::::::::::::::::::::::::::::
XP_005 MLDQAENELENGTTWQNPEPPVDFRVMEKD
10 20 30
170 180 190 200 210 220
pF1KE5 RANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYS
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE5 EEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFN
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE5 GRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYL
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE5 SPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSH
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE5 KRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRR
280 290 300 310 320 330
470 480
pF1KE5 SGNRDRTVQSPKSK
:
XP_005 SETGSCYVAQTGGQWLFT
340
>>XP_016885372 (OMIM: 300028) PREDICTED: U2 small nuclea (348 aa)
initn: 2502 init1: 2331 opt: 2331 Z-score: 994.8 bits: 193.0 E(85289): 1.1e-48
Smith-Waterman score: 2331; 100.0% identity (100.0% similar) in 331 aa overlap (139-469:1-331)
110 120 130 140 150 160
pF1KE5 EQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKD
::::::::::::::::::::::::::::::
XP_016 MLDQAENELENGTTWQNPEPPVDFRVMEKD
10 20 30
170 180 190 200 210 220
pF1KE5 RANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYS
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE5 EEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFN
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE5 GRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYL
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE5 SPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSH
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE5 KRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRR
280 290 300 310 320 330
470 480
pF1KE5 SGNRDRTVQSPKSK
:
XP_016 SETGSCYVAQTGGQWLFT
340
>>XP_016885371 (OMIM: 300028) PREDICTED: U2 small nuclea (348 aa)
initn: 2502 init1: 2331 opt: 2331 Z-score: 994.8 bits: 193.0 E(85289): 1.1e-48
Smith-Waterman score: 2331; 100.0% identity (100.0% similar) in 331 aa overlap (139-469:1-331)
110 120 130 140 150 160
pF1KE5 EQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKD
::::::::::::::::::::::::::::::
XP_016 MLDQAENELENGTTWQNPEPPVDFRVMEKD
10 20 30
170 180 190 200 210 220
pF1KE5 RANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYS
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE5 EEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFN
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE5 GRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYL
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE5 SPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSH
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE5 KRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRR
280 290 300 310 320 330
470 480
pF1KE5 SGNRDRTVQSPKSK
:
XP_016 SETGSCYVAQTGGQWLFT
340
>>NP_001020374 (OMIM: 191317) splicing factor U2AF 35 kD (240 aa)
initn: 490 init1: 230 opt: 460 Z-score: 223.5 bits: 49.7 E(85289): 1e-05
Smith-Waterman score: 477; 36.0% identity (61.1% similar) in 239 aa overlap (166-403:12-234)
140 150 160 170 180 190
pF1KE5 LQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFGDRCSRKHNFPT
:::..:: :: : :::: :::::: :: ::
NP_001 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPT
10 20 30 40
200 210 220 230 240 250
pF1KE5 SSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFYEDVLPEFKN-VGKVI
: :.::.... . : . : . :. : ... .:.:.:. :... :.:
NP_001 FSQTILIQNIYRN---PQNSAQTAD-GSHCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVE
50 60 70 80 90
260 270 280 290 300 310
pF1KE5 QFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCEFCPVTRWKMAICGL
...: :: :: :::::... ::. . :. .:.::. :. .. :. ::: .. : :
NP_001 EMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQ
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE5 FEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKNSERRERMGHHDDYY
.:. .: :: :::.:. .: .. : :..: . : ... ::: :
NP_001 YEMGECTRGGFCNFMHL--KPISR--ELRRELYGRRRKKHRSRSRSRERRSR--------
160 170 180 190 200
380 390 400 410 420 430
pF1KE5 SRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRS
:: ::: . . . . : .:. :: :
NP_001 SRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF
210 220 230 240
>>NP_006749 (OMIM: 191317) splicing factor U2AF 35 kDa s (240 aa)
initn: 475 init1: 230 opt: 444 Z-score: 216.9 bits: 48.5 E(85289): 2.4e-05
Smith-Waterman score: 461; 35.1% identity (60.3% similar) in 239 aa overlap (166-403:12-234)
140 150 160 170 180 190
pF1KE5 LQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFGDRCSRKHNFPT
:::..:: :: : :::: :::::: :: ::
NP_006 MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPT
10 20 30 40
200 210 220 230 240 250
pF1KE5 SSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFYEDVLPEFKN-VGKVI
: :. .... . : .. : :. : ... .:.:.:. :... :.:
NP_006 FSQTI---ALLNIYRNPQNSSQSAD-GLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVE
50 60 70 80 90
260 270 280 290 300 310
pF1KE5 QFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCEFCPVTRWKMAICGL
...: :: :: :::::... ::. . :. .:.::. :. .. :. ::: .. : :
NP_006 EMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQ
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE5 FEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKNSERRERMGHHDDYY
.:. .: :: :::.:. .: .. : :..: . : ... ::: :
NP_006 YEMGECTRGGFCNFMHL--KPISR--ELRRELYGRRRKKHRSRSRSRERRSR--------
160 170 180 190 200
380 390 400 410 420 430
pF1KE5 SRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRS
:: ::: . . . . : .:. :: :
NP_006 SRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF
210 220 230 240
482 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:24:36 2016 done: Tue Nov 8 05:24:37 2016
Total Scan time: 8.810 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]