Result of FASTA (omim) for
pFN21AE3128
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3128, 318 aa
1>>>pF1KE3128 318 - 318 aa - 318 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0150+/-0.00049; mu= 10.6501+/- 0.030
mean_var=55.5833+/-11.373, 0's: 0 Z-trim(107.4): 41 B-trim: 100 in 1/51
Lambda= 0.172029
statistics sampled from 15441 (15477) to 15441 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.532), E-opt: 0.2 (0.181), width: 16
Scan time: 6.830
The best scores are: opt bits E(85289)
NP_002756 (OMIM: 311860) ribose-phosphate pyrophos ( 318) 2051 517.7 1.2e-146
NP_001034180 (OMIM: 311860) ribose-phosphate pyrop ( 321) 2035 513.7 2e-145
NP_002755 (OMIM: 300661,301835,311070,311850) ribo ( 318) 1990 502.6 4.5e-142
NP_787082 (OMIM: 611566) ribose-phosphate pyrophos ( 318) 1896 479.2 4.7e-135
NP_001191331 (OMIM: 300661,301835,311070,311850) r ( 114) 717 186.7 2e-47
NP_001230869 (OMIM: 603762) phosphoribosyl pyropho ( 320) 607 159.3 9.5e-39
XP_016880364 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 375 101.8 1.8e-21
XP_016880363 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 375 101.8 1.8e-21
XP_016880361 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 375 101.8 1.8e-21
XP_016880362 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 375 101.8 1.8e-21
XP_016880360 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 375 101.8 1.8e-21
XP_005256786 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 375 101.8 1.8e-21
NP_001230871 (OMIM: 603762) phosphoribosyl pyropho ( 283) 375 101.8 1.8e-21
NP_001230870 (OMIM: 603762) phosphoribosyl pyropho ( 283) 375 101.8 1.8e-21
XP_016880365 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 375 101.8 1.8e-21
XP_016880357 (OMIM: 603762) PREDICTED: phosphoribo ( 324) 375 101.7 2.1e-21
XP_016880359 (OMIM: 603762) PREDICTED: phosphoribo ( 324) 375 101.7 2.1e-21
XP_016880358 (OMIM: 603762) PREDICTED: phosphoribo ( 324) 375 101.7 2.1e-21
NP_001230865 (OMIM: 603762) phosphoribosyl pyropho ( 329) 375 101.7 2.1e-21
XP_005256782 (OMIM: 603762) PREDICTED: phosphoribo ( 369) 375 101.7 2.4e-21
NP_002758 (OMIM: 603762) phosphoribosyl pyrophosph ( 369) 375 101.7 2.4e-21
XP_005256783 (OMIM: 603762) PREDICTED: phosphoribo ( 369) 375 101.7 2.4e-21
XP_016880355 (OMIM: 603762) PREDICTED: phosphoribo ( 369) 375 101.7 2.4e-21
XP_016880356 (OMIM: 603762) PREDICTED: phosphoribo ( 369) 375 101.7 2.4e-21
XP_016880354 (OMIM: 603762) PREDICTED: phosphoribo ( 369) 375 101.7 2.4e-21
XP_016880353 (OMIM: 603762) PREDICTED: phosphoribo ( 423) 375 101.7 2.7e-21
NP_001317432 (OMIM: 601249) phosphoribosyl pyropho ( 282) 352 96.0 9.4e-20
NP_002757 (OMIM: 601249) phosphoribosyl pyrophosph ( 385) 352 96.0 1.3e-19
>>NP_002756 (OMIM: 311860) ribose-phosphate pyrophosphok (318 aa)
initn: 2051 init1: 2051 opt: 2051 Z-score: 2753.6 bits: 517.7 E(85289): 1.2e-146
Smith-Waterman score: 2051; 100.0% identity (100.0% similar) in 318 aa overlap (1-318:1-318)
10 20 30 40 50 60
pF1KE3 MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAI
250 260 270 280 290 300
310
pF1KE3 RRTHNGESVSYLFSHVPL
::::::::::::::::::
NP_002 RRTHNGESVSYLFSHVPL
310
>>NP_001034180 (OMIM: 311860) ribose-phosphate pyrophosp (321 aa)
initn: 1409 init1: 1409 opt: 2035 Z-score: 2732.0 bits: 513.7 E(85289): 2e-145
Smith-Waterman score: 2035; 99.1% identity (99.1% similar) in 321 aa overlap (1-318:1-321)
10 20 30 40 50 60
pF1KE3 MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGC
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 GEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDK---SRAPISAKLVANMLS
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
NP_001 GEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKVGESRAPISAKLVANMLS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 VAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 VTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 SAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILA
250 260 270 280 290 300
300 310
pF1KE3 EAIRRTHNGESVSYLFSHVPL
:::::::::::::::::::::
NP_001 EAIRRTHNGESVSYLFSHVPL
310 320
>>NP_002755 (OMIM: 300661,301835,311070,311850) ribose-p (318 aa)
initn: 1990 init1: 1990 opt: 1990 Z-score: 2671.7 bits: 502.6 E(85289): 4.5e-142
Smith-Waterman score: 1990; 95.3% identity (98.7% similar) in 318 aa overlap (1-318:1-318)
10 20 30 40 50 60
pF1KE3 MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGC
:::: .:::::::::::..::::::::::::::::::::: ::::::::::::::.::::
NP_002 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
NP_002 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTS
::::::::::::::::::::::::::::::::.::::::.::.:: ::::::::::::::
NP_002 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAI
::.::::::::::::::::::::: :::::::::::::::::::.:::::::::::::::
NP_002 ATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAI
250 260 270 280 290 300
310
pF1KE3 RRTHNGESVSYLFSHVPL
::::::::::::::::::
NP_002 RRTHNGESVSYLFSHVPL
310
>>NP_787082 (OMIM: 611566) ribose-phosphate pyrophosphok (318 aa)
initn: 1896 init1: 1896 opt: 1896 Z-score: 2545.6 bits: 479.2 E(85289): 4.7e-135
Smith-Waterman score: 1896; 91.2% identity (97.5% similar) in 318 aa overlap (1-318:1-318)
10 20 30 40 50 60
pF1KE3 MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGC
:::: .:::::::::::..::::::::::::::::::::: ::: ::::::::::.::::
NP_787 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIVQSGC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG
:::::.:::::::::::::::.::::::::::::::::::::::.::::::::::::.::
NP_787 GEINDSLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRSPISAKLVANMLSIAG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTS
:::::::::::::::::::::::::::::.::.:::::: ::::::::::::::::::::
NP_787 ADHIITMDLHASQIQGFFDIPVDNLYAEPTVLKWIRENIPEWKNCIIVSPDAGGAKRVTS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG
:::.:::.::::::::::::::: .::::::.:::::::::::::: ::: :::::::::
NP_787 IADQLNVDFALIHKERKKANEVDCIVLVGDVNDRVAILVDDMADTCVTICLAADKLLSAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAI
::.:::::::::::::::::::.: ::::::::::::..:::::.::.::::::::::::
NP_787 ATRVYAILTHGIFSGPAISRINTACFEAVVVTNTIPQDEKMKHCSKIRVIDISMILAEAI
250 260 270 280 290 300
310
pF1KE3 RRTHNGESVSYLFSHVPL
::::::::::::::::::
NP_787 RRTHNGESVSYLFSHVPL
310
>>NP_001191331 (OMIM: 300661,301835,311070,311850) ribos (114 aa)
initn: 717 init1: 717 opt: 717 Z-score: 972.5 bits: 186.7 E(85289): 2e-47
Smith-Waterman score: 717; 97.4% identity (99.1% similar) in 114 aa overlap (205-318:1-114)
180 190 200 210 220 230
pF1KE3 AKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAAD
::::::::::::::::::::::::::::::
NP_001 MVLVGDVKDRVAILVDDMADTCGTICHAAD
10 20 30
240 250 260 270 280 290
pF1KE3 KLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISM
::::::::.::::::::::::::::::::: :::::::::::::::::::.:::::::::
NP_001 KLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISM
40 50 60 70 80 90
300 310
pF1KE3 ILAEAIRRTHNGESVSYLFSHVPL
::::::::::::::::::::::::
NP_001 ILAEAIRRTHNGESVSYLFSHVPL
100 110
>>NP_001230869 (OMIM: 603762) phosphoribosyl pyrophospha (320 aa)
initn: 836 init1: 316 opt: 607 Z-score: 816.7 bits: 159.3 E(85289): 9.5e-39
Smith-Waterman score: 762; 45.3% identity (71.1% similar) in 318 aa overlap (4-318:20-318)
10 20 30 40
pF1KE3 MPNIVLFSGSSHQ---DLSQRVADRLGLELGKVVTKKFSNQETS
.::::..:.. .::...:.:::.:.::: . . :.::
NP_001 MFCVTPPELETKMNITKGGLVLFSANSNSSCMELSKKIAERLGVEMGKVQVYQEPNRETR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 VEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKD
:.: :::::.::.:::. ..: ..::::::. ::: . .. . .::: :::..: :
NP_001 VQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAE
: :. : .::.:.:. :: :.:::::: ..:::::.:::::: : : .::.:.:.: .
NP_001 K-RGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPD
130 140 150 160 170
170 180 190 200 210 220
pF1KE3 WKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDD
..: .::. . ..:::. :.:.:: . .:.:: : . : : : :: : .
NP_001 YRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDA-ESD---LV-DGRHS-----PP
180 190 200 210 220
230 240 250 260 270 280
pF1KE3 MADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKM
:. . ..: : . .. . : . : .: :: :. .::::::::.: .
NP_001 MVRSVAAI-HPSLEIPMLIPKEKPPITVVGDVGG----RI---AIIVVVVTNTIPHEVQK
230 240 250 260 270 280
290 300 310
pF1KE3 KHCTKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL
.: ::...::::::.::::: :::::.:::: .. :
NP_001 LQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD
290 300 310 320
>>XP_016880364 (OMIM: 603762) PREDICTED: phosphoribosyl (283 aa)
initn: 770 init1: 368 opt: 375 Z-score: 506.5 bits: 101.8 E(85289): 1.8e-21
Smith-Waterman score: 719; 44.3% identity (68.8% similar) in 282 aa overlap (68-318:1-281)
40 50 60 70 80 90
pF1KE3 QETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQ
::::::. ::: . .. . .::: :::..:
XP_016 MELLIMVYACKTSCAKSIIGVIPYFPYSKQ
10 20 30
100 110 120 130 140 150
pF1KE3 DKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRE
: : :. : .::.:.:. :: :.:::::: ..:::::.:::::: : : .::.:.:
XP_016 CKMRK-RGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQE
40 50 60 70 80
160 170 180 190 200
pF1KE3 NIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKAN-----------------
.: ...: .::. . ..:::. :.:.:: . .:.:: : . :.
XP_016 EIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVA
90 100 110 120 130 140
210 220 230 240
pF1KE3 ------EVDRMV--------LVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYA
:. .. .:::: :.::.:::. : .. ::. : :: :...
XP_016 AIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFV
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE3 ILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIRRTHNG
. :::..:. : ::...:.. ::::::::.: . .: ::...::::::.::::: :::
XP_016 MATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNG
210 220 230 240 250 260
310
pF1KE3 ESVSYLFSHVPL
::.:::: .. :
XP_016 ESMSYLFRNIGLDD
270 280
>>XP_016880363 (OMIM: 603762) PREDICTED: phosphoribosyl (283 aa)
initn: 770 init1: 368 opt: 375 Z-score: 506.5 bits: 101.8 E(85289): 1.8e-21
Smith-Waterman score: 719; 44.3% identity (68.8% similar) in 282 aa overlap (68-318:1-281)
40 50 60 70 80 90
pF1KE3 QETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQ
::::::. ::: . .. . .::: :::..:
XP_016 MELLIMVYACKTSCAKSIIGVIPYFPYSKQ
10 20 30
100 110 120 130 140 150
pF1KE3 DKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRE
: : :. : .::.:.:. :: :.:::::: ..:::::.:::::: : : .::.:.:
XP_016 CKMRK-RGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQE
40 50 60 70 80
160 170 180 190 200
pF1KE3 NIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKAN-----------------
.: ...: .::. . ..:::. :.:.:: . .:.:: : . :.
XP_016 EIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVA
90 100 110 120 130 140
210 220 230 240
pF1KE3 ------EVDRMV--------LVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYA
:. .. .:::: :.::.:::. : .. ::. : :: :...
XP_016 AIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFV
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE3 ILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIRRTHNG
. :::..:. : ::...:.. ::::::::.: . .: ::...::::::.::::: :::
XP_016 MATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNG
210 220 230 240 250 260
310
pF1KE3 ESVSYLFSHVPL
::.:::: .. :
XP_016 ESMSYLFRNIGLDD
270 280
>>XP_016880361 (OMIM: 603762) PREDICTED: phosphoribosyl (283 aa)
initn: 770 init1: 368 opt: 375 Z-score: 506.5 bits: 101.8 E(85289): 1.8e-21
Smith-Waterman score: 719; 44.3% identity (68.8% similar) in 282 aa overlap (68-318:1-281)
40 50 60 70 80 90
pF1KE3 QETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQ
::::::. ::: . .. . .::: :::..:
XP_016 MELLIMVYACKTSCAKSIIGVIPYFPYSKQ
10 20 30
100 110 120 130 140 150
pF1KE3 DKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRE
: : :. : .::.:.:. :: :.:::::: ..:::::.:::::: : : .::.:.:
XP_016 CKMRK-RGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQE
40 50 60 70 80
160 170 180 190 200
pF1KE3 NIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKAN-----------------
.: ...: .::. . ..:::. :.:.:: . .:.:: : . :.
XP_016 EIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVA
90 100 110 120 130 140
210 220 230 240
pF1KE3 ------EVDRMV--------LVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYA
:. .. .:::: :.::.:::. : .. ::. : :: :...
XP_016 AIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFV
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE3 ILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIRRTHNG
. :::..:. : ::...:.. ::::::::.: . .: ::...::::::.::::: :::
XP_016 MATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNG
210 220 230 240 250 260
310
pF1KE3 ESVSYLFSHVPL
::.:::: .. :
XP_016 ESMSYLFRNIGLDD
270 280
>>XP_016880362 (OMIM: 603762) PREDICTED: phosphoribosyl (283 aa)
initn: 770 init1: 368 opt: 375 Z-score: 506.5 bits: 101.8 E(85289): 1.8e-21
Smith-Waterman score: 719; 44.3% identity (68.8% similar) in 282 aa overlap (68-318:1-281)
40 50 60 70 80 90
pF1KE3 QETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQ
::::::. ::: . .. . .::: :::..:
XP_016 MELLIMVYACKTSCAKSIIGVIPYFPYSKQ
10 20 30
100 110 120 130 140 150
pF1KE3 DKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRE
: : :. : .::.:.:. :: :.:::::: ..:::::.:::::: : : .::.:.:
XP_016 CKMRK-RGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQE
40 50 60 70 80
160 170 180 190 200
pF1KE3 NIAEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKAN-----------------
.: ...: .::. . ..:::. :.:.:: . .:.:: : . :.
XP_016 EIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVA
90 100 110 120 130 140
210 220 230 240
pF1KE3 ------EVDRMV--------LVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYA
:. .. .:::: :.::.:::. : .. ::. : :: :...
XP_016 AIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFV
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE3 ILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAIRRTHNG
. :::..:. : ::...:.. ::::::::.: . .: ::...::::::.::::: :::
XP_016 MATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNG
210 220 230 240 250 260
310
pF1KE3 ESVSYLFSHVPL
::.:::: .. :
XP_016 ESMSYLFRNIGLDD
270 280
318 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:52:36 2016 done: Sun Nov 6 12:52:37 2016
Total Scan time: 6.830 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]