Result of FASTA (omim) for
pFN21AE2593
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2593, 332 aa
1>>>pF1KE2593 332 - 332 aa - 332 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1747+/-0.000452; mu= -4.6258+/- 0.028
mean_var=392.9476+/-78.317, 0's: 0 Z-trim(121.7): 30 B-trim: 0 in 0/58
Lambda= 0.064700
statistics sampled from 38642 (38681) to 38642 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.454), width: 16
Scan time: 7.860
The best scores are: opt bits E(85289)
NP_001164657 (OMIM: 300477) protein FAM9A [Homo sa ( 332) 2116 211.2 2.6e-54
NP_777611 (OMIM: 300477) protein FAM9A [Homo sapie ( 332) 2116 211.2 2.6e-54
NP_995321 (OMIM: 300478) protein FAM9B [Homo sapie ( 186) 542 63.9 3e-10
XP_011543766 (OMIM: 300478) PREDICTED: protein FAM ( 186) 542 63.9 3e-10
XP_005274517 (OMIM: 300479) PREDICTED: protein FAM ( 166) 484 58.5 1.2e-08
NP_777561 (OMIM: 300479) protein FAM9C [Homo sapie ( 166) 484 58.5 1.2e-08
XP_016884810 (OMIM: 300479) PREDICTED: protein FAM ( 166) 484 58.5 1.2e-08
XP_011543767 (OMIM: 300478) PREDICTED: protein FAM ( 114) 457 55.8 5.2e-08
>>NP_001164657 (OMIM: 300477) protein FAM9A [Homo sapien (332 aa)
initn: 2116 init1: 2116 opt: 2116 Z-score: 1096.2 bits: 211.2 E(85289): 2.6e-54
Smith-Waterman score: 2116; 100.0% identity (100.0% similar) in 332 aa overlap (1-332:1-332)
10 20 30 40 50 60
pF1KE2 MEPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 EEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLRE
250 260 270 280 290 300
310 320 330
pF1KE2 MKPLLEQLLKAAKDTKDNYCIISSSEESELDN
::::::::::::::::::::::::::::::::
NP_001 MKPLLEQLLKAAKDTKDNYCIISSSEESELDN
310 320 330
>>NP_777611 (OMIM: 300477) protein FAM9A [Homo sapiens] (332 aa)
initn: 2116 init1: 2116 opt: 2116 Z-score: 1096.2 bits: 211.2 E(85289): 2.6e-54
Smith-Waterman score: 2116; 100.0% identity (100.0% similar) in 332 aa overlap (1-332:1-332)
10 20 30 40 50 60
pF1KE2 MEPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 MEPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 EAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 EAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 EHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 EHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 YIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 EEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_777 EEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLRE
250 260 270 280 290 300
310 320 330
pF1KE2 MKPLLEQLLKAAKDTKDNYCIISSSEESELDN
::::::::::::::::::::::::::::::::
NP_777 MKPLLEQLLKAAKDTKDNYCIISSSEESELDN
310 320 330
>>NP_995321 (OMIM: 300478) protein FAM9B [Homo sapiens] (186 aa)
initn: 549 init1: 322 opt: 542 Z-score: 305.1 bits: 63.9 E(85289): 3e-10
Smith-Waterman score: 584; 46.8% identity (57.7% similar) in 267 aa overlap (66-332:2-186)
40 50 60 70 80 90
pF1KE2 SNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREED
:: .:::.::::::::::::: ::::::::
NP_995 MAAWGKKHAGKDPVRDECEERNRFTETREED
10 20 30
100 110 120 130 140 150
pF1KE2 VTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERA
::::::::::::: ::::: .: : : : : :.:::. .:.::. :::: ..:
NP_995 VTDEHGEREPFAETDEHTGANTKKPEDTAED----LTAKRKRMKMDKTC-SKTKNKSKHA
40 50 60 70 80
160 170 180 190 200 210
pF1KE2 LKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAE
:.::::::::::: :. ::::::.:::...::
NP_995 LRKKQLKRQKRDYIHSLKLLNVLEEYITDEQK----------------------------
90 100 110
220 230 240 250 260 270
pF1KE2 VIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEE
:::::::::: :
NP_995 ------------------EEEEEEGEEE-------------------------------E
120
280 290 300 310 320 330
pF1KE2 QIKAFQEKQKRWQQPTGVRSWRLREMKPLLEQLLKAAKDTKDNYCIISSSEESELDN
:. :::.::.::: .:: ::.::: : .:..:: .: .: . :.:.:::::
NP_995 LIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDEDSELDN
130 140 150 160 170 180
>>XP_011543766 (OMIM: 300478) PREDICTED: protein FAM9B i (186 aa)
initn: 549 init1: 322 opt: 542 Z-score: 305.1 bits: 63.9 E(85289): 3e-10
Smith-Waterman score: 584; 46.8% identity (57.7% similar) in 267 aa overlap (66-332:2-186)
40 50 60 70 80 90
pF1KE2 SNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREED
:: .:::.::::::::::::: ::::::::
XP_011 MAAWGKKHAGKDPVRDECEERNRFTETREED
10 20 30
100 110 120 130 140 150
pF1KE2 VTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERA
::::::::::::: ::::: .: : : : : :.:::. .:.::. :::: ..:
XP_011 VTDEHGEREPFAETDEHTGANTKKPEDTAED----LTAKRKRMKMDKTC-SKTKNKSKHA
40 50 60 70 80
160 170 180 190 200 210
pF1KE2 LKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAE
:.::::::::::: :. ::::::.:::...::
XP_011 LRKKQLKRQKRDYIHSLKLLNVLEEYITDEQK----------------------------
90 100 110
220 230 240 250 260 270
pF1KE2 VIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEE
:::::::::: :
XP_011 ------------------EEEEEEGEEE-------------------------------E
120
280 290 300 310 320 330
pF1KE2 QIKAFQEKQKRWQQPTGVRSWRLREMKPLLEQLLKAAKDTKDNYCIISSSEESELDN
:. :::.::.::: .:: ::.::: : .:..:: .: .: . :.:.:::::
XP_011 LIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDEDSELDN
130 140 150 160 170 180
>>XP_005274517 (OMIM: 300479) PREDICTED: protein FAM9C i (166 aa)
initn: 616 init1: 483 opt: 484 Z-score: 276.4 bits: 58.5 E(85289): 1.2e-08
Smith-Waterman score: 484; 61.2% identity (77.0% similar) in 139 aa overlap (55-192:2-139)
30 40 50 60 70 80
pF1KE2 QGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEE
::: :::.:: :: . .::::: : ::
XP_005 MAAKDQLEVQVMAAQEMELAGKDPVSHEHEE
10 20 30
90 100 110 120 130 140
pF1KE2 RNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMI-KIDKA
:.: :::.: ::::::::: ::: :::::. : .:: ::::::. :::::. : :: ::
XP_005 RKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIAADIKEHLAAKRKRIEKIAKA
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 AYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEA
. :: :. .:. :::::::::: . :: :::.:.:...:::.:..
XP_005 C-SEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGEKEEQIKIFQ
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 AAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEE
XP_005 EQQKRWQQDGKGTERD
160
>>NP_777561 (OMIM: 300479) protein FAM9C [Homo sapiens] (166 aa)
initn: 616 init1: 483 opt: 484 Z-score: 276.4 bits: 58.5 E(85289): 1.2e-08
Smith-Waterman score: 484; 61.2% identity (77.0% similar) in 139 aa overlap (55-192:2-139)
30 40 50 60 70 80
pF1KE2 QGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEE
::: :::.:: :: . .::::: : ::
NP_777 MAAKDQLEVQVMAAQEMELAGKDPVSHEHEE
10 20 30
90 100 110 120 130 140
pF1KE2 RNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMI-KIDKA
:.: :::.: ::::::::: ::: :::::. : .:: ::::::. :::::. : :: ::
NP_777 RKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIAADIKEHLAAKRKRIEKIAKA
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 AYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEA
. :: :. .:. :::::::::: . :: :::.:.:...:::.:..
NP_777 C-SEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGEKEEQIKIFQ
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 AAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEE
NP_777 EQQKRWQQDGKGTERD
160
>>XP_016884810 (OMIM: 300479) PREDICTED: protein FAM9C i (166 aa)
initn: 616 init1: 483 opt: 484 Z-score: 276.4 bits: 58.5 E(85289): 1.2e-08
Smith-Waterman score: 484; 61.2% identity (77.0% similar) in 139 aa overlap (55-192:2-139)
30 40 50 60 70 80
pF1KE2 QGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEE
::: :::.:: :: . .::::: : ::
XP_016 MAAKDQLEVQVMAAQEMELAGKDPVSHEHEE
10 20 30
90 100 110 120 130 140
pF1KE2 RNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMI-KIDKA
:.: :::.: ::::::::: ::: :::::. : .:: ::::::. :::::. : :: ::
XP_016 RKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIAADIKEHLAAKRKRIEKIAKA
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 AYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEA
. :: :. .:. :::::::::: . :: :::.:.:...:::.:..
XP_016 C-SEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITDEQKDEEGDGEKEEQIKIFQ
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 AAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEE
XP_016 EQQKRWQQDGKGTERD
160
>>XP_011543767 (OMIM: 300478) PREDICTED: protein FAM9B i (114 aa)
initn: 516 init1: 361 opt: 457 Z-score: 264.7 bits: 55.8 E(85289): 5.2e-08
Smith-Waterman score: 457; 76.6% identity (84.0% similar) in 94 aa overlap (31-124:16-105)
10 20 30 40 50 60
pF1KE2 MEPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQL
::::::.:::::. .:::: .::::::
XP_011 MPGFLSFLSVSLRSPGSGIASSFPGQPATDPVGR----RAAKAQL
10 20 30 40
70 80 90 100 110 120
pF1KE2 EAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKL
::: :: .:::.::::::::::::: ::::::::::::::::::::: ::::: .: :
XP_011 EAQFMAAWGKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 EHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKE
: :
XP_011 EDTAVIFSYTNWN
110
332 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:44:40 2016 done: Tue Nov 8 16:44:41 2016
Total Scan time: 7.860 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]