Result of FASTA (omim) for
pFN21AE1927
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1927, 433 aa
1>>>pF1KE1927 433 - 433 aa - 433 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4842+/-0.000314; mu= 8.3333+/- 0.020
mean_var=124.2845+/-25.256, 0's: 0 Z-trim(120.7): 443 B-trim: 1237 in 1/54
Lambda= 0.115044
statistics sampled from 35715 (36186) to 35715 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.424), width: 16
Scan time: 7.890
The best scores are: opt bits E(85289)
NP_851852 (OMIM: 609405) rho GTPase-activating pro ( 433) 2910 493.6 4e-139
NP_001017526 (OMIM: 609405) rho GTPase-activating ( 464) 2224 379.8 8e-105
NP_001185655 (OMIM: 609405) rho GTPase-activating ( 305) 2004 343.2 5.5e-94
XP_011518397 (OMIM: 602732) PREDICTED: rho GTPase- ( 439) 1496 259.0 1.8e-68
NP_004299 (OMIM: 602732) rho GTPase-activating pro ( 439) 1496 259.0 1.8e-68
XP_016873209 (OMIM: 602732) PREDICTED: rho GTPase- ( 395) 1025 180.8 5.6e-45
XP_016869847 (OMIM: 610691) PREDICTED: protein pru ( 337) 362 70.7 6.5e-12
NP_001294978 (OMIM: 610691) protein prune homolog ( 337) 362 70.7 6.5e-12
NP_001294979 (OMIM: 610691) protein prune homolog ( 352) 362 70.7 6.8e-12
NP_001317609 (OMIM: 610691) protein prune homolog ( 353) 362 70.7 6.8e-12
XP_016869848 (OMIM: 610691) PREDICTED: protein pru ( 336) 359 70.2 9.2e-12
XP_016869845 (OMIM: 610691) PREDICTED: protein pru ( 352) 359 70.2 9.6e-12
XP_016869843 (OMIM: 610691) PREDICTED: protein pru ( 365) 359 70.2 9.9e-12
XP_011538307 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 363 71.0 9.9e-12
XP_005270071 (OMIM: 610585) PREDICTED: rho GTPase- ( 624) 363 71.0 9.9e-12
XP_011538309 (OMIM: 610585) PREDICTED: rho GTPase- ( 637) 363 71.0 1e-11
NP_001242953 (OMIM: 610585) rho GTPase-activating ( 714) 363 71.0 1.1e-11
XP_011538304 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 363 71.0 1.1e-11
XP_011538305 (OMIM: 610585) PREDICTED: rho GTPase- ( 720) 363 71.0 1.1e-11
XP_011538317 (OMIM: 610585) PREDICTED: rho GTPase- ( 359) 353 69.2 1.9e-11
XP_011538315 (OMIM: 610585) PREDICTED: rho GTPase- ( 436) 353 69.3 2.3e-11
NP_001294980 (OMIM: 610691) protein prune homolog ( 324) 349 68.5 2.8e-11
NP_149053 (OMIM: 601238,608179) caytaxin [Homo sap ( 371) 348 68.4 3.5e-11
NP_056040 (OMIM: 610691) protein prune homolog 2 i (3088) 362 71.1 4.4e-11
XP_011516625 (OMIM: 610691) PREDICTED: protein pru (3089) 362 71.1 4.4e-11
XP_016869834 (OMIM: 610691) PREDICTED: protein pru (3091) 362 71.1 4.4e-11
XP_005251802 (OMIM: 610691) PREDICTED: protein pru (3092) 362 71.1 4.4e-11
NP_001307603 (OMIM: 603292) BCL2/adenovirus E1B 19 ( 447) 347 68.3 4.7e-11
NP_001307604 (OMIM: 603292) BCL2/adenovirus E1B 19 ( 376) 345 67.9 5.1e-11
NP_004321 (OMIM: 603292) BCL2/adenovirus E1B 19 kD ( 435) 345 67.9 5.7e-11
XP_016869841 (OMIM: 610691) PREDICTED: protein pru (3071) 359 70.6 6.2e-11
XP_016869840 (OMIM: 610691) PREDICTED: protein pru (3072) 359 70.6 6.2e-11
XP_011516630 (OMIM: 610691) PREDICTED: protein pru (3072) 359 70.6 6.2e-11
XP_016869839 (OMIM: 610691) PREDICTED: protein pru (3074) 359 70.6 6.2e-11
XP_005251808 (OMIM: 610691) PREDICTED: protein pru (3075) 359 70.6 6.2e-11
XP_011516628 (OMIM: 610691) PREDICTED: protein pru (3085) 359 70.6 6.2e-11
XP_016869835 (OMIM: 610691) PREDICTED: protein pru (3087) 359 70.6 6.2e-11
XP_005251807 (OMIM: 610691) PREDICTED: protein pru (3088) 359 70.6 6.2e-11
XP_005251805 (OMIM: 610691) PREDICTED: protein pru (3090) 359 70.6 6.2e-11
XP_005251803 (OMIM: 610691) PREDICTED: protein pru (3091) 359 70.6 6.2e-11
XP_006717049 (OMIM: 610691) PREDICTED: protein pru (3100) 359 70.6 6.2e-11
XP_006717048 (OMIM: 610691) PREDICTED: protein pru (3101) 359 70.6 6.2e-11
XP_006717047 (OMIM: 610691) PREDICTED: protein pru (3101) 359 70.6 6.2e-11
XP_006717046 (OMIM: 610691) PREDICTED: protein pru (3103) 359 70.6 6.2e-11
XP_006717045 (OMIM: 610691) PREDICTED: protein pru (3104) 359 70.6 6.2e-11
XP_016871959 (OMIM: 610585) PREDICTED: rho GTPase- ( 655) 346 68.2 7.3e-11
XP_011538308 (OMIM: 610585) PREDICTED: rho GTPase- ( 661) 346 68.2 7.3e-11
NP_001036134 (OMIM: 610586) rho GTPase-activating ( 653) 345 68.0 8.1e-11
XP_011530602 (OMIM: 610586) PREDICTED: rho GTPase- ( 653) 345 68.0 8.1e-11
NP_112595 (OMIM: 610586) rho GTPase-activating pro ( 655) 345 68.0 8.2e-11
>>NP_851852 (OMIM: 609405) rho GTPase-activating protein (433 aa)
initn: 2910 init1: 2910 opt: 2910 Z-score: 2618.7 bits: 493.6 E(85289): 4e-139
Smith-Waterman score: 2910; 99.8% identity (99.8% similar) in 433 aa overlap (1-433:1-433)
10 20 30 40 50 60
pF1KE1 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 TLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 WNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPPTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 WNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPPTK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 TPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 REIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 REIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_851 TGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 SALVPLNMFTELLIEYYEKIFSTLEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPT
::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_851 SALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPT
370 380 390 400 410 420
430
pF1KE1 LPPSPLMAARRRL
:::::::::::::
NP_851 LPPSPLMAARRRL
430
>>NP_001017526 (OMIM: 609405) rho GTPase-activating prot (464 aa)
initn: 2224 init1: 2224 opt: 2224 Z-score: 2002.9 bits: 379.8 E(85289): 8e-105
Smith-Waterman score: 2838; 93.1% identity (93.1% similar) in 464 aa overlap (1-433:1-464)
10 20 30 40 50 60
pF1KE1 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKY
10 20 30 40 50 60
70 80 90 100
pF1KE1 TLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRK--------------------
::::::::::::::::::::::::::::::::::::::::
NP_001 TLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKDGDLTMWPRLVSNSKLKRSS
70 80 90 100 110 120
110 120 130 140
pF1KE1 -----------YKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLSLPKYWDYRYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHL
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE1 KYDQLVIPPEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KYDQLVIPPEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELI
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE1 PPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILK
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE1 TFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVS
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE1 RESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTLEAPGE
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_001 RESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGE
370 380 390 400 410 420
390 400 410 420 430
pF1KE1 HGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL
::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL
430 440 450 460
>>NP_001185655 (OMIM: 609405) rho GTPase-activating prot (305 aa)
initn: 2004 init1: 2004 opt: 2004 Z-score: 1808.4 bits: 343.2 E(85289): 5.5e-94
Smith-Waterman score: 2004; 100.0% identity (100.0% similar) in 294 aa overlap (1-294:1-294)
10 20 30 40 50 60
pF1KE1 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 TLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 WNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPPTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPPTK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 TPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 REIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVPGEHLQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 TGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSL
NP_001 QNEQL
>>XP_011518397 (OMIM: 602732) PREDICTED: rho GTPase-acti (439 aa)
initn: 1508 init1: 1359 opt: 1496 Z-score: 1350.3 bits: 259.0 E(85289): 1.8e-68
Smith-Waterman score: 1496; 57.1% identity (84.3% similar) in 382 aa overlap (8-388:58-438)
10 20 30
pF1KE1 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVT
:. . :.::.::: :..:::::..::....
XP_011 IDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 FSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEF
:: :::::::.:::..:: :::.:::::::.:::..:.:.::.: :::::.::..::.::
XP_011 FSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREF
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE1 DRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIP
:::::::.::::.:::: :::.: ..::::: :::.:..: :::::: ::.: .:: ::
XP_011 DRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIP
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE1 PEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKN-QGELIPPVLRFT
.::.::. :.: ... . : : :::::::.::::::::.:..:: . : :: ::: :
XP_011 RQVLKYDDFLKSTQKSPATAP-KPMPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRET
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE1 VTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELP
:.::. ..: :::.:::::..:.:::.:. ::.: ::.::.:...:.:::::::::::::
XP_011 VAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELP
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 QPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNK
.:::::. : ...:. .. : :: . :.:..:::.:: :::.: .:: .: .: ::
XP_011 EPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNK
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE1 MNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTLEAPGEHGLAPWE
:...::: ::: ::.: .... .:.:. :.: ::..:... ..: . . :
XP_011 MTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDPSGL
390 400 410 420 430
400 410 420 430
pF1KE1 QGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL
>>NP_004299 (OMIM: 602732) rho GTPase-activating protein (439 aa)
initn: 1508 init1: 1359 opt: 1496 Z-score: 1350.3 bits: 259.0 E(85289): 1.8e-68
Smith-Waterman score: 1496; 57.1% identity (84.3% similar) in 382 aa overlap (8-388:58-438)
10 20 30
pF1KE1 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVT
:. . :.::.::: :..:::::..::....
NP_004 IDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 FSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEF
:: :::::::.:::..:: :::.:::::::.:::..:.:.::.: :::::.::..::.::
NP_004 FSACRMPPSHQLDHSKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWLRDAYREF
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE1 DRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIP
:::::::.::::.:::: :::.: ..::::: :::.:..: :::::: ::.: .:: ::
NP_004 DRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIP
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE1 PEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKN-QGELIPPVLRFT
.::.::. :.: ... . : : :::::::.::::::::.:..:: . : :: ::: :
NP_004 RQVLKYDDFLKSTQKSPATAP-KPMPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRET
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE1 VTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELP
:.::. ..: :::.:::::..:.:::.:. ::.: ::.::.:...:.:::::::::::::
NP_004 VAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELP
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE1 QPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNK
.:::::. : ...:. .. : :: . :.:..:::.:: :::.: .:: .: .: ::
NP_004 EPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNK
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE1 MNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTLEAPGEHGLAPWE
:...::: ::: ::.: .... .:.:. :.: ::..:... ..: . . :
NP_004 MTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDPSGL
390 400 410 420 430
400 410 420 430
pF1KE1 QGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL
>>XP_016873209 (OMIM: 602732) PREDICTED: rho GTPase-acti (395 aa)
initn: 1250 init1: 903 opt: 1025 Z-score: 928.5 bits: 180.8 E(85289): 5.6e-45
Smith-Waterman score: 1167; 49.0% identity (73.3% similar) in 382 aa overlap (8-388:58-394)
10 20 30
pF1KE1 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVT
:. . :.::.::: :..:::::..::....
XP_016 IDEKNWPSDEMPDFPKSDDSKSSSPELVTHLKWDDPYYDIARHQIVEVAGDDKYGRKIIV
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE1 FSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEF
:: :::::::.:::..:: :
XP_016 FSACRMPPSHQLDHSKLL----------------------G-------------------
90 100
100 110 120 130 140 150
pF1KE1 DRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIP
::::.::::.:::: :::.: ..::::: :::.:..: :::::: ::.: .:: ::
XP_016 ---YKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVKLEQLGIP
110 120 130 140 150 160
160 170 180 190 200 210
pF1KE1 PEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKN-QGELIPPVLRFT
.::.::. :.: ... . : : :::::::.::::::::.:..:: . : :: ::: :
XP_016 RQVLKYDDFLKSTQKSPATAP-KPMPPRPPLPNQQFGVSLQHLQEKNPEQEPIPIVLRET
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE1 VTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELP
:.::. ..: :::.:::::..:.:::.:. ::.: ::.::.:...:.:::::::::::::
XP_016 VAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVILKTFLRELP
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE1 QPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNK
.:::::. : ...:. .. : :: . :.:..:::.:: :::.: .:: .: .: ::
XP_016 EPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTLPEENYQVLRFLTAFLVQISAHSDQNK
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE1 MNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTLEAPGEHGLAPWE
:...::: ::: ::.: .... .:.:. :.: ::..:... ..: . . :
XP_016 MTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFPSPDPSGL
350 360 370 380 390
400 410 420 430
pF1KE1 QGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL
>>XP_016869847 (OMIM: 610691) PREDICTED: protein prune h (337 aa)
initn: 304 init1: 304 opt: 362 Z-score: 334.9 bits: 70.7 E(85289): 6.5e-12
Smith-Waterman score: 362; 32.3% identity (61.5% similar) in 195 aa overlap (13-203:150-336)
10 20 30 40
pF1KE1 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCR
:. : :: :: ...:. :
XP_016 TAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHG--GYYGDGL--NAIIVFAACF
120 130 140 150 160 170
50 60 70 80 90
pF1KE1 MPPSHELDHQRLLE----YLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFD
.: : . :.. ..: :. ::. .: .:: :::.. . : :.:::... :. .:
XP_016 LPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMID
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE1 RKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPP
:. .::::.. .:::. ::... . .:.:: ::..:. : : :::: . .: . ::
XP_016 RRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPE
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE1 EVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVT
... ::.:. :. :. : . ... ..:. ::.:
XP_016 SIIKLDEELR---EASEAAKTSCLYNDPEMSSMEKDIDLK-LKEKP
300 310 320 330
220 230 240 250 260 270
pF1KE1 YLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQP
>>NP_001294978 (OMIM: 610691) protein prune homolog 2 is (337 aa)
initn: 304 init1: 304 opt: 362 Z-score: 334.9 bits: 70.7 E(85289): 6.5e-12
Smith-Waterman score: 362; 32.3% identity (61.5% similar) in 195 aa overlap (13-203:150-336)
10 20 30 40
pF1KE1 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCR
:. : :: :: ...:. :
NP_001 TAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHG--GYYGDGL--NAIIVFAACF
120 130 140 150 160 170
50 60 70 80 90
pF1KE1 MPPSHELDHQRLLE----YLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFD
.: : . :.. ..: :. ::. .: .:: :::.. . : :.:::... :. .:
NP_001 LPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMID
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE1 RKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPP
:. .::::.. .:::. ::... . .:.:: ::..:. : : :::: . .: . ::
NP_001 RRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPE
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE1 EVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVT
... ::.:. :. :. : . ... ..:. ::.:
NP_001 SIIKLDEELR---EASEAAKTSCLYNDPEMSSMEKDIDLK-LKEKP
300 310 320 330
220 230 240 250 260 270
pF1KE1 YLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQP
>>NP_001294979 (OMIM: 610691) protein prune homolog 2 is (352 aa)
initn: 304 init1: 304 opt: 362 Z-score: 334.6 bits: 70.7 E(85289): 6.8e-12
Smith-Waterman score: 362; 32.3% identity (61.5% similar) in 195 aa overlap (13-203:165-351)
10 20 30 40
pF1KE1 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCR
:. : :: :: ...:. :
NP_001 TAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHG--GYYGDGL--NAIIVFAACF
140 150 160 170 180 190
50 60 70 80 90
pF1KE1 MPPSHELDHQRLLE----YLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFD
.: : . :.. ..: :. ::. .: .:: :::.. . : :.:::... :. .:
NP_001 LPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMID
200 210 220 230 240 250
100 110 120 130 140 150
pF1KE1 RKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPP
:. .::::.. .:::. ::... . .:.:: ::..:. : : :::: . .: . ::
NP_001 RRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPE
260 270 280 290 300 310
160 170 180 190 200 210
pF1KE1 EVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVT
... ::.:. :. :. : . ... ..:. ::.:
NP_001 SIIKLDEELR---EASEAAKTSCLYNDPEMSSMEKDIDLK-LKEKP
320 330 340 350
220 230 240 250 260 270
pF1KE1 YLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQP
>>NP_001317609 (OMIM: 610691) protein prune homolog 2 is (353 aa)
initn: 304 init1: 304 opt: 362 Z-score: 334.5 bits: 70.7 E(85289): 6.8e-12
Smith-Waterman score: 362; 32.3% identity (61.5% similar) in 195 aa overlap (13-203:166-352)
10 20 30 40
pF1KE1 MAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCR
:. : :: :: ...:. :
NP_001 TAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHG--GYYGDGL--NAIIVFAACF
140 150 160 170 180 190
50 60 70 80 90
pF1KE1 MPPSHELDHQRLLE----YLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFD
.: : . :.. ..: :. ::. .: .:: :::.. . : :.:::... :. .:
NP_001 LPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMID
200 210 220 230 240 250
100 110 120 130 140 150
pF1KE1 RKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPP
:. .::::.. .:::. ::... . .:.:: ::..:. : : :::: . .: . ::
NP_001 RRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPE
260 270 280 290 300 310
160 170 180 190 200 210
pF1KE1 EVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVT
... ::.:. :. :. : . ... ..:. ::.:
NP_001 SIIKLDEELR---EASEAAKTSCLYNDPEMSSMEKDIDLK-LKEKP
320 330 340 350
220 230 240 250 260 270
pF1KE1 YLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQP
433 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 12:54:28 2016 done: Sun Nov 6 12:54:29 2016
Total Scan time: 7.890 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]