Result of FASTA (ccds) for
pFN21AE2642
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2642, 397 aa
1>>>pF1KE2642 397 - 397 aa - 397 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0774+/-0.00095; mu= 13.1897+/- 0.057
mean_var=82.7059+/-16.237, 0's: 0 Z-trim(106.2): 37 B-trim: 2 in 1/50
Lambda= 0.141028
statistics sampled from 8848 (8875) to 8848 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.659), E-opt: 0.2 (0.273), width: 16
Scan time: 2.580
The best scores are: opt bits E(32554)
CCDS46724.1 PARVB gene_id:29780|Hs108|chr22 ( 397) 2597 538.3 4.7e-153
CCDS14056.1 PARVB gene_id:29780|Hs108|chr22 ( 364) 2102 437.5 9.1e-123
CCDS58808.1 PARVB gene_id:29780|Hs108|chr22 ( 327) 2098 436.7 1.5e-122
CCDS44541.2 PARVA gene_id:55742|Hs108|chr11 ( 412) 1612 337.9 1e-92
CCDS74874.1 PARVB gene_id:29780|Hs108|chr22 ( 289) 1325 279.4 2.9e-75
CCDS14057.1 PARVG gene_id:64098|Hs108|chr22 ( 331) 863 185.4 6.4e-47
>>CCDS46724.1 PARVB gene_id:29780|Hs108|chr22 (397 aa)
initn: 2597 init1: 2597 opt: 2597 Z-score: 2861.3 bits: 538.3 E(32554): 4.7e-153
Smith-Waterman score: 2597; 99.7% identity (100.0% similar) in 397 aa overlap (1-397:1-397)
10 20 30 40 50 60
pF1KE2 MHHVFKDHQRGEKRGFLSPENKNCRRLELRRGCSCSWGLCSQALMASLAGSLLPGSDRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MHHVFKDHQRGEKRGFLSPENKNCRRLELRRGCSCSWGLCSQALMASLAGSLLPGSDRSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQLEENEERTMIDPTSKEDPKFK
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
CCDS46 VETSEYAQGGVSDLQEEGKNAINSPMSPALVDVHPEDTQLEENEERTMIDPTSKEDPKFK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 ELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 VVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLITFVNKH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELML
310 320 330 340 350 360
370 380 390
pF1KE2 DGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
:::::::::::::::::::::::::::::::::::::
CCDS46 DGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
370 380 390
>>CCDS14056.1 PARVB gene_id:29780|Hs108|chr22 (364 aa)
initn: 2102 init1: 2102 opt: 2102 Z-score: 2317.6 bits: 437.5 E(32554): 9.1e-123
Smith-Waterman score: 2102; 99.7% identity (100.0% similar) in 327 aa overlap (71-397:38-364)
50 60 70 80 90 100
pF1KE2 SQALMASLAGSLLPGSDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQL
::::::::::::::::::::.:::::::::
CCDS14 PTPRPRRMKKDESFLGKLGGTLARKRRAREVSDLQEEGKNAINSPMSPALVDVHPEDTQL
10 20 30 40 50 60
110 120 130 140 150 160
pF1KE2 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
70 80 90 100 110 120
170 180 190 200 210 220
pF1KE2 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLV
130 140 150 160 170 180
230 240 250 260 270 280
pF1KE2 SLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 SLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFD
190 200 210 220 230 240
290 300 310 320 330 340
pF1KE2 HAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 HAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYL
250 260 270 280 290 300
350 360 370 380 390
pF1KE2 TPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 TPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
310 320 330 340 350 360
>>CCDS58808.1 PARVB gene_id:29780|Hs108|chr22 (327 aa)
initn: 2098 init1: 2098 opt: 2098 Z-score: 2313.9 bits: 436.7 E(32554): 1.5e-122
Smith-Waterman score: 2098; 99.4% identity (100.0% similar) in 327 aa overlap (71-397:1-327)
50 60 70 80 90 100
pF1KE2 SQALMASLAGSLLPGSDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQL
.:::::::::::::::::::.:::::::::
CCDS58 MSDLQEEGKNAINSPMSPALVDVHPEDTQL
10 20 30
110 120 130 140 150 160
pF1KE2 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE2 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE2 SLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 SLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFD
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE2 HAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 HAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYL
220 230 240 250 260 270
350 360 370 380 390
pF1KE2 TPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 TPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
280 290 300 310 320
>>CCDS44541.2 PARVA gene_id:55742|Hs108|chr11 (412 aa)
initn: 1611 init1: 1611 opt: 1612 Z-score: 1777.9 bits: 337.9 E(32554): 1e-92
Smith-Waterman score: 1612; 76.0% identity (91.2% similar) in 329 aa overlap (71-397:86-412)
50 60 70 80 90 100
pF1KE2 SQALMASLAGSLLPGSDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQL
::.::::: :::: :.:: .. ::::.:
CCDS44 TPKSPPSRKKDDSFLGKLGGTLARRKKAKEVSELQEEGMNAINLPLSPIPFELDPEDTML
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 EENEERTMIDPTSKEDPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEK
:::: :::.::.:. :::..::.:::.:::::::: ::::::.: ::::::::::::.::
CCDS44 EENEVRTMVDPNSRSDPKLQELMKVLIDWINDVLVGERIIVKDLAEDLYDGQVLQKLFEK
120 130 140 150 160 170
170 180 190 200 210
pF1KE2 LAGCKLNVAEVTQSEIGQKQKLQTVLEAVHDLLR--PRGWALRWSVDSIHGKNLVAILHL
: . ::::::::::::.:::::::::: ... :. :: ...:.:::.:.:.:::::::
CCDS44 LESEKLNVAEVTQSEIAQKQKLQTVLEKINETLKLPPR--SIKWNVDSVHAKSLVAILHL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE2 LVSLAMHFRAPIRLPEHVTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTL
::.:...::::::::.::..:::::.::::.:.: .:.::.: .:: . :: ::::::::
CCDS44 LVALSQYFRAPIRLPDHVSIQVVVVQKREGILQSRQIQEEITGNTEALSGRHERDAFDTL
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE2 FDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHF
::::::::.::::.::::::::::::::::::::::::::::::::::::: :::::: :
CCDS44 FDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSF
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE2 YLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
.:::.::.::: ::::::::: ::::.::: ::::.:: ::::::::::::::::.:::
CCDS44 FLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE
360 370 380 390 400 410
>>CCDS74874.1 PARVB gene_id:29780|Hs108|chr22 (289 aa)
initn: 1325 init1: 1325 opt: 1325 Z-score: 1464.7 bits: 279.4 E(32554): 2.9e-75
Smith-Waterman score: 1815; 92.3% identity (92.6% similar) in 312 aa overlap (86-397:1-289)
60 70 80 90 100 110
pF1KE2 SDRSGVETSEYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQLEENEERTMIDPTSKE
:::::.::::::::::::::::::::::::
CCDS74 MSPALVDVHPEDTQLEENEERTMIDPTSKE
10 20 30
120 130 140 150 160 170
pF1KE2 DPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 DPKFKELVKVLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSE
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE2 IGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 IGQKQKLQTVLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEH
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE2 VTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKKSLIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 VTVQVVVVRKREGLLHSSHISEELTTTTEMMMGRFERDAFDTLFDHAPDKLSVVKK----
160 170 180 190 200
300 310 320 330 340 350
pF1KE2 FVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFA
:::::::::::::::::::::::::::::::::::::::::
CCDS74 -------------------FADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFA
210 220 230 240
360 370 380 390
pF1KE2 FELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
::::::::::::::::::::::::::::::::::::::::::
CCDS74 FELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
250 260 270 280
>>CCDS14057.1 PARVG gene_id:64098|Hs108|chr22 (331 aa)
initn: 862 init1: 465 opt: 863 Z-score: 955.8 bits: 185.4 E(32554): 6.4e-47
Smith-Waterman score: 863; 45.2% identity (78.7% similar) in 301 aa overlap (95-393:19-316)
70 80 90 100 110 120
pF1KE2 EYAQGGVSDLQEEGKNAINSPMSPALADVHPEDTQLEENEERTMIDPTSKEDPKFKELVK
: . .: .. .. .. :::..::::.:: :
CCDS14 MEPEFLYDLLQLPKGVEPPAEEELSKGGKKKYLPPTSRKDPKFEELQK
10 20 30 40
130 140 150 160 170 180
pF1KE2 VLLDWINDVLVEERIIVKQLEEDLYDGQVLQKLLEKLAGCKLNVAEVTQSEIGQKQKLQT
::..::: .:. :.:.:..::::..:: .:..:...::. ::.. ... . .::.:: .
CCDS14 VLMEWINATLLPEHIVVRSLEEDMFDGLILHHLFQRLAALKLEAEDIALTATSQKHKLTV
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE2 VLEAVHDLLRPRGWALRWSVDSIHGKNLVAILHLLVSLAMHFRAPIRLPEHVTVQVVVVR
:::::. :. . : .:::.:: .:.:.. :::::.:: .:. . :: .: :.:....
CCDS14 VLEAVNRSLQLEEWQAKWSVESIFNKDLLSTLHLLVALAKRFQPDLSLPTNVQVEVITIE
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE2 KREGLLHSSHISEELTTTTEMMMGRFE--RDAFDTLFDHAPDKLSVVKKSLITFVNKHLN
. .. :.: .. :.:: :. . : .:.:: :: ::.:...::.....:::..:.
CCDS14 STKSGLKSEKLVEQLT---EYSTDKDEPPKDVFDELFKLAPEKVNAVKEAIVNFVNQKLD
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE2 KLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDG
.:.: : .:.::::::: :.::.: :: .:. :..:::::.: . .:::..:.::. :
CCDS14 RLGLSVQNLDTQFADGVILLLLIGQLEGFFLHLKEFYLTPNSPAEMLHNVTLALELLKDE
230 240 250 260 270 280
370 380 390
pF1KE2 GLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
:: . . :::.:: : ::::::::.:: :.
CCDS14 GLLSCPVSPEDIVNKDAKSTLRVLYGLFCKHTQKAHRDRTPHGAPN
290 300 310 320 330
397 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:43:22 2016 done: Tue Nov 8 17:43:22 2016
Total Scan time: 2.580 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]