Result of FASTA (omim) for
pFN21AE6451
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6451, 504 aa
1>>>pF1KE6451 504 - 504 aa - 504 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5933+/-0.00029; mu= 19.1999+/- 0.018
mean_var=103.0332+/-20.324, 0's: 0 Z-trim(119.7): 77 B-trim: 58 in 1/60
Lambda= 0.126353
statistics sampled from 34004 (34086) to 34004 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.4), width: 16
Scan time: 8.680
The best scores are: opt bits E(85289)
XP_016884174 (OMIM: 610409) PREDICTED: monocarboxy ( 504) 3337 618.6 1.3e-176
NP_037488 (OMIM: 610409) monocarboxylate transport ( 504) 3337 618.6 1.3e-176
NP_001257552 (OMIM: 603654) monocarboxylate transp ( 478) 1364 258.9 2.4e-68
NP_004722 (OMIM: 603654) monocarboxylate transport ( 478) 1364 258.9 2.4e-68
XP_005269288 (OMIM: 603654) PREDICTED: monocarboxy ( 478) 1364 258.9 2.4e-68
NP_001257551 (OMIM: 603654) monocarboxylate transp ( 478) 1364 258.9 2.4e-68
XP_011537293 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 1083 207.7 6.6e-53
XP_011537291 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 1083 207.7 6.6e-53
XP_011537294 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 1083 207.7 6.6e-53
XP_011537292 (OMIM: 603654) PREDICTED: monocarboxy ( 504) 1083 207.7 6.6e-53
NP_004198 (OMIM: 603877) monocarboxylate transport ( 465) 1022 196.5 1.4e-49
XP_011521909 (OMIM: 603877) PREDICTED: monocarboxy ( 465) 1022 196.5 1.4e-49
NP_001035887 (OMIM: 603877) monocarboxylate transp ( 465) 1022 196.5 1.4e-49
NP_001035888 (OMIM: 603877) monocarboxylate transp ( 465) 1022 196.5 1.4e-49
NP_001193881 (OMIM: 603877) monocarboxylate transp ( 465) 1022 196.5 1.4e-49
NP_001193879 (OMIM: 603877) monocarboxylate transp ( 465) 1022 196.5 1.4e-49
NP_001193880 (OMIM: 603877) monocarboxylate transp ( 465) 1022 196.5 1.4e-49
XP_016875713 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 962 185.5 2.3e-46
XP_011537295 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 962 185.5 2.3e-46
XP_016875716 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 962 185.5 2.3e-46
XP_016875714 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 962 185.5 2.3e-46
XP_016875715 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 962 185.5 2.3e-46
XP_011537297 (OMIM: 603654) PREDICTED: monocarboxy ( 379) 962 185.5 2.3e-46
NP_998771 (OMIM: 611910,612018) monocarboxylate tr ( 516) 856 166.3 1.9e-40
XP_016871728 (OMIM: 611910,612018) PREDICTED: mono ( 516) 856 166.3 1.9e-40
XP_016871726 (OMIM: 611910,612018) PREDICTED: mono ( 516) 856 166.3 1.9e-40
XP_016871727 (OMIM: 611910,612018) PREDICTED: mono ( 516) 856 166.3 1.9e-40
XP_011540329 (OMIM: 245340,600682,610021,616095) P ( 500) 809 157.7 7.1e-38
NP_003042 (OMIM: 245340,600682,610021,616095) mono ( 500) 809 157.7 7.1e-38
XP_011540328 (OMIM: 245340,600682,610021,616095) P ( 500) 809 157.7 7.1e-38
NP_001159968 (OMIM: 245340,600682,610021,616095) m ( 500) 809 157.7 7.1e-38
NP_001258694 (OMIM: 603879) monocarboxylate transp ( 505) 658 130.2 1.4e-29
NP_004686 (OMIM: 603879) monocarboxylate transport ( 505) 658 130.2 1.4e-29
XP_005257847 (OMIM: 603879) PREDICTED: monocarboxy ( 545) 658 130.2 1.5e-29
XP_011523764 (OMIM: 603879) PREDICTED: monocarboxy ( 532) 656 129.9 1.8e-29
NP_699188 (OMIM: 615765) monocarboxylate transport ( 471) 632 125.4 3.5e-28
XP_016879770 (OMIM: 615765) PREDICTED: monocarboxy ( 511) 632 125.5 3.7e-28
XP_005256545 (OMIM: 615765) PREDICTED: monocarboxy ( 566) 632 125.5 4e-28
NP_004685 (OMIM: 603880) monocarboxylate transport ( 523) 491 99.8 2.1e-20
NP_001167637 (OMIM: 603880) monocarboxylate transp ( 523) 491 99.8 2.1e-20
XP_016880781 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 491 99.8 2.1e-20
XP_016880780 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 491 99.8 2.1e-20
XP_011523763 (OMIM: 603880) PREDICTED: monocarboxy ( 523) 491 99.8 2.1e-20
XP_005257846 (OMIM: 603880) PREDICTED: monocarboxy ( 527) 491 99.8 2.1e-20
XP_016871373 (OMIM: 614242) PREDICTED: monocarboxy ( 509) 464 94.9 6.1e-19
NP_001310910 (OMIM: 614242) monocarboxylate transp ( 509) 464 94.9 6.1e-19
NP_919274 (OMIM: 614242) monocarboxylate transport ( 509) 464 94.9 6.1e-19
XP_016871372 (OMIM: 614242) PREDICTED: monocarboxy ( 551) 464 94.9 6.5e-19
XP_016880782 (OMIM: 603879) PREDICTED: monocarboxy ( 435) 438 90.0 1.5e-17
XP_011533724 (OMIM: 607550) PREDICTED: monocarboxy ( 321) 406 84.1 6.7e-16
>>XP_016884174 (OMIM: 610409) PREDICTED: monocarboxylate (504 aa)
initn: 3337 init1: 3337 opt: 3337 Z-score: 3291.5 bits: 618.6 E(85289): 1.3e-176
Smith-Waterman score: 3337; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)
10 20 30 40 50 60
pF1KE6 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 RLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 GALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 ALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEALE
430 440 450 460 470 480
490 500
pF1KE6 VLSARGEPTEPEIEARPRLAAESV
::::::::::::::::::::::::
XP_016 VLSARGEPTEPEIEARPRLAAESV
490 500
>>NP_037488 (OMIM: 610409) monocarboxylate transporter 3 (504 aa)
initn: 3337 init1: 3337 opt: 3337 Z-score: 3291.5 bits: 618.6 E(85289): 1.3e-176
Smith-Waterman score: 3337; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)
10 20 30 40 50 60
pF1KE6 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 RLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 RLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 VARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 GALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 ALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 ALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEALE
430 440 450 460 470 480
490 500
pF1KE6 VLSARGEPTEPEIEARPRLAAESV
::::::::::::::::::::::::
NP_037 VLSARGEPTEPEIEARPRLAAESV
490 500
>>NP_001257552 (OMIM: 603654) monocarboxylate transporte (478 aa)
initn: 1356 init1: 833 opt: 1364 Z-score: 1348.0 bits: 258.9 E(85289): 2.4e-68
Smith-Waterman score: 1364; 46.8% identity (76.2% similar) in 425 aa overlap (12-436:13-430)
10 20 30 40 50
pF1KE6 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAW
::::::::.:.:: :. ::.:.:::::.:::. ... : . ::. ::
NP_001 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 VSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLT
.::::::..:. :::::.::...: :::..::::: ::.::::.. ...:::: : .:
NP_001 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLL
:::::.:.::.: ..: :: :.::.::::: ::::::::.:.:..: :.. :::.:.::.
NP_001 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LGGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPR
::.:::. :. :..::: :: ... ... . :..: :.. ... . .
NP_001 LGSLLLNACVAGSLMRP---LGP----NQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKV
190 200 210 220 230
240 250 260 270 280 290
pF1KE6 RRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVD
. ::... :.: .: . .: ::.:.: :.:. :::: :. . .::::::...:::
NP_001 NKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 IVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGM
. :::. : .:. .::.. :.::.:.. ::. : :..: .:: . : :::..:
NP_001 MFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGS
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 VGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSE
:... ::.:: :::::: ::.::: .:: . ::.::: ::.:::. .:. ... :.
NP_001 VSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAI
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 VALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEAL
:. :.:.. ... :
NP_001 VVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSE
420 430 440 450 460 470
>>NP_004722 (OMIM: 603654) monocarboxylate transporter 2 (478 aa)
initn: 1356 init1: 833 opt: 1364 Z-score: 1348.0 bits: 258.9 E(85289): 2.4e-68
Smith-Waterman score: 1364; 46.8% identity (76.2% similar) in 425 aa overlap (12-436:13-430)
10 20 30 40 50
pF1KE6 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAW
::::::::.:.:: :. ::.:.:::::.:::. ... : . ::. ::
NP_004 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 VSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLT
.::::::..:. :::::.::...: :::..::::: ::.::::.. ...:::: : .:
NP_004 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLL
:::::.:.::.: ..: :: :.::.::::: ::::::::.:.:..: :.. :::.:.::.
NP_004 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LGGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPR
::.:::. :. :..::: :: ... ... . :..: :.. ... . .
NP_004 LGSLLLNACVAGSLMRP---LGP----NQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKV
190 200 210 220 230
240 250 260 270 280 290
pF1KE6 RRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVD
. ::... :.: .: . .: ::.:.: :.:. :::: :. . .::::::...:::
NP_004 NKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 IVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGM
. :::. : .:. .::.. :.::.:.. ::. : :..: .:: . : :::..:
NP_004 MFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGS
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 VGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSE
:... ::.:: :::::: ::.::: .:: . ::.::: ::.:::. .:. ... :.
NP_004 VSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAI
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 VALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEAL
:. :.:.. ... :
NP_004 VVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSE
420 430 440 450 460 470
>>XP_005269288 (OMIM: 603654) PREDICTED: monocarboxylate (478 aa)
initn: 1356 init1: 833 opt: 1364 Z-score: 1348.0 bits: 258.9 E(85289): 2.4e-68
Smith-Waterman score: 1364; 46.8% identity (76.2% similar) in 425 aa overlap (12-436:13-430)
10 20 30 40 50
pF1KE6 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAW
::::::::.:.:: :. ::.:.:::::.:::. ... : . ::. ::
XP_005 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 VSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLT
.::::::..:. :::::.::...: :::..::::: ::.::::.. ...:::: : .:
XP_005 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLL
:::::.:.::.: ..: :: :.::.::::: ::::::::.:.:..: :.. :::.:.::.
XP_005 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LGGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPR
::.:::. :. :..::: :: ... ... . :..: :.. ... . .
XP_005 LGSLLLNACVAGSLMRP---LGP----NQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKV
190 200 210 220 230
240 250 260 270 280 290
pF1KE6 RRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVD
. ::... :.: .: . .: ::.:.: :.:. :::: :. . .::::::...:::
XP_005 NKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 IVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGM
. :::. : .:. .::.. :.::.:.. ::. : :..: .:: . : :::..:
XP_005 MFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGS
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 VGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSE
:... ::.:: :::::: ::.::: .:: . ::.::: ::.:::. .:. ... :.
XP_005 VSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAI
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 VALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEAL
:. :.:.. ... :
XP_005 VVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSE
420 430 440 450 460 470
>>NP_001257551 (OMIM: 603654) monocarboxylate transporte (478 aa)
initn: 1356 init1: 833 opt: 1364 Z-score: 1348.0 bits: 258.9 E(85289): 2.4e-68
Smith-Waterman score: 1364; 46.8% identity (76.2% similar) in 425 aa overlap (12-436:13-430)
10 20 30 40 50
pF1KE6 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAW
::::::::.:.:: :. ::.:.:::::.:::. ... : . ::. ::
NP_001 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 VSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLT
.::::::..:. :::::.::...: :::..::::: ::.::::.. ...:::: : .:
NP_001 ISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLL
:::::.:.::.: ..: :: :.::.::::: ::::::::.:.:..: :.. :::.:.::.
NP_001 GLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LGGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPR
::.:::. :. :..::: :: ... ... . :..: :.. ... . .
NP_001 LGSLLLNACVAGSLMRP---LGP----NQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKV
190 200 210 220 230
240 250 260 270 280 290
pF1KE6 RRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVD
. ::... :.: .: . .: ::.:.: :.:. :::: :. . .::::::...:::
NP_001 NKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 IVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGM
. :::. : .:. .::.. :.::.:.. ::. : :..: .:: . : :::..:
NP_001 MFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGS
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 VGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSE
:... ::.:: :::::: ::.::: .:: . ::.::: ::.:::. .:. ... :.
NP_001 VSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAI
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 VALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEAL
:. :.:.. ... :
NP_001 VVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSE
420 430 440 450 460 470
>>XP_011537293 (OMIM: 603654) PREDICTED: monocarboxylate (504 aa)
initn: 1075 init1: 552 opt: 1083 Z-score: 1070.9 bits: 207.7 E(85289): 6.6e-53
Smith-Waterman score: 1304; 44.3% identity (72.1% similar) in 451 aa overlap (12-436:13-456)
10 20 30 40 50
pF1KE6 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAW
::::::::.:.:: :. ::.:.:::::.:::. ... : . ::. ::
XP_011 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90
pF1KE6 VSSIMLAMLY------------------------GT--GPVSSILVTRFGCRPVMLAGGL
.::::::..: :. :::::.::...: :::..::::
XP_011 ISSIMLAVMYAGGRIFESFLIFTSLRIQCSFTQSGSCLGPVSSVLVNKYGSRPVVIAGGL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 LASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGS
: ::.::::.. ...:::: : .::::::.:.::.: ..: :: :.::.::::: :::
XP_011 LCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGS
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 PVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRA
:::::.:.:..: :.. :::.:.::.::.:::. :. :..::: :: ... ...
XP_011 PVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRP---LGP----NQTTSKS
190 200 210 220 230
220 230 240 250 260 270
pF1KE6 GDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAIL
. :..: :.. ... . . . ::... :.: .: . .: ::.:.: :.
XP_011 KNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIF
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE6 LVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLT
:. :::: :. . .::::::...:::. :::. : .:. .::.. :.::.:.. ::.
XP_011 LAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVC
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE6 DLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVL
: :..: .:: . : :::..: :... ::.:: :::::: ::.::: .:: . ::
XP_011 HLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVL
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE6 IGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASD
.::: ::.:::. .:. ... :. :. :.:.. ... :
XP_011 LGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRE
420 430 440 450 460 470
460 470 480 490 500
pF1KE6 TEDAEAEGDSEPLPVVAEEPGNLEALEVLSARGEPTEPEIEARPRLAAESV
XP_011 SEPLSKSKHSEDVNVKVSNAQSVTSERETNI
480 490 500
>>XP_011537291 (OMIM: 603654) PREDICTED: monocarboxylate (504 aa)
initn: 1075 init1: 552 opt: 1083 Z-score: 1070.9 bits: 207.7 E(85289): 6.6e-53
Smith-Waterman score: 1304; 44.3% identity (72.1% similar) in 451 aa overlap (12-436:13-456)
10 20 30 40 50
pF1KE6 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAW
::::::::.:.:: :. ::.:.:::::.:::. ... : . ::. ::
XP_011 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90
pF1KE6 VSSIMLAMLY------------------------GT--GPVSSILVTRFGCRPVMLAGGL
.::::::..: :. :::::.::...: :::..::::
XP_011 ISSIMLAVMYAGGRIFESFLIFTSLRIQCSFTQSGSCLGPVSSVLVNKYGSRPVVIAGGL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 LASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGS
: ::.::::.. ...:::: : .::::::.:.::.: ..: :: :.::.::::: :::
XP_011 LCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGS
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 PVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRA
:::::.:.:..: :.. :::.:.::.::.:::. :. :..::: :: ... ...
XP_011 PVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRP---LGP----NQTTSKS
190 200 210 220 230
220 230 240 250 260 270
pF1KE6 GDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAIL
. :..: :.. ... . . . ::... :.: .: . .: ::.:.: :.
XP_011 KNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIF
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE6 LVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLT
:. :::: :. . .::::::...:::. :::. : .:. .::.. :.::.:.. ::.
XP_011 LAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVC
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE6 DLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVL
: :..: .:: . : :::..: :... ::.:: :::::: ::.::: .:: . ::
XP_011 HLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVL
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE6 IGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASD
.::: ::.:::. .:. ... :. :. :.:.. ... :
XP_011 LGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRE
420 430 440 450 460 470
460 470 480 490 500
pF1KE6 TEDAEAEGDSEPLPVVAEEPGNLEALEVLSARGEPTEPEIEARPRLAAESV
XP_011 SEPLSKSKHSEDVNVKVSNAQSVTSERETNI
480 490 500
>>XP_011537294 (OMIM: 603654) PREDICTED: monocarboxylate (504 aa)
initn: 1075 init1: 552 opt: 1083 Z-score: 1070.9 bits: 207.7 E(85289): 6.6e-53
Smith-Waterman score: 1304; 44.3% identity (72.1% similar) in 451 aa overlap (12-436:13-456)
10 20 30 40 50
pF1KE6 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAW
::::::::.:.:: :. ::.:.:::::.:::. ... : . ::. ::
XP_011 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90
pF1KE6 VSSIMLAMLY------------------------GT--GPVSSILVTRFGCRPVMLAGGL
.::::::..: :. :::::.::...: :::..::::
XP_011 ISSIMLAVMYAGGRIFESFLIFTSLRIQCSFTQSGSCLGPVSSVLVNKYGSRPVVIAGGL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 LASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGS
: ::.::::.. ...:::: : .::::::.:.::.: ..: :: :.::.::::: :::
XP_011 LCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGS
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 PVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRA
:::::.:.:..: :.. :::.:.::.::.:::. :. :..::: :: ... ...
XP_011 PVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRP---LGP----NQTTSKS
190 200 210 220 230
220 230 240 250 260 270
pF1KE6 GDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAIL
. :..: :.. ... . . . ::... :.: .: . .: ::.:.: :.
XP_011 KNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIF
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE6 LVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLT
:. :::: :. . .::::::...:::. :::. : .:. .::.. :.::.:.. ::.
XP_011 LAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVC
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE6 DLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVL
: :..: .:: . : :::..: :... ::.:: :::::: ::.::: .:: . ::
XP_011 HLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVL
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE6 IGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASD
.::: ::.:::. .:. ... :. :. :.:.. ... :
XP_011 LGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRE
420 430 440 450 460 470
460 470 480 490 500
pF1KE6 TEDAEAEGDSEPLPVVAEEPGNLEALEVLSARGEPTEPEIEARPRLAAESV
XP_011 SEPLSKSKHSEDVNVKVSNAQSVTSERETNI
480 490 500
>>XP_011537292 (OMIM: 603654) PREDICTED: monocarboxylate (504 aa)
initn: 1075 init1: 552 opt: 1083 Z-score: 1070.9 bits: 207.7 E(85289): 6.6e-53
Smith-Waterman score: 1304; 44.3% identity (72.1% similar) in 451 aa overlap (12-436:13-456)
10 20 30 40 50
pF1KE6 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAW
::::::::.:.:: :. ::.:.:::::.:::. ... : . ::. ::
XP_011 MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAW
10 20 30 40 50 60
60 70 80 90
pF1KE6 VSSIMLAMLY------------------------GT--GPVSSILVTRFGCRPVMLAGGL
.::::::..: :. :::::.::...: :::..::::
XP_011 ISSIMLAVMYAGGRIFESFLIFTSLRIQCSFTQSGSCLGPVSSVLVNKYGSRPVVIAGGL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 LASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGS
: ::.::::.. ...:::: : .::::::.:.::.: ..: :: :.::.::::: :::
XP_011 LCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGS
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 PVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRA
:::::.:.:..: :.. :::.:.::.::.:::. :. :..::: :: ... ...
XP_011 PVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRP---LGP----NQTTSKS
190 200 210 220 230
220 230 240 250 260 270
pF1KE6 GDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAIL
. :..: :.. ... . . . ::... :.: .: . .: ::.:.: :.
XP_011 KNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIF
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE6 LVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLT
:. :::: :. . .::::::...:::. :::. : .:. .::.. :.::.:.. ::.
XP_011 LAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVC
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE6 DLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVL
: :..: .:: . : :::..: :... ::.:: :::::: ::.::: .:: . ::
XP_011 HLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVL
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE6 IGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASD
.::: ::.:::. .:. ... :. :. :.:.. ... :
XP_011 LGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRE
420 430 440 450 460 470
460 470 480 490 500
pF1KE6 TEDAEAEGDSEPLPVVAEEPGNLEALEVLSARGEPTEPEIEARPRLAAESV
XP_011 SEPLSKSKHSEDVNVKVSNAQSVTSERETNI
480 490 500
504 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:26:18 2016 done: Tue Nov 8 13:26:19 2016
Total Scan time: 8.680 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]