Result of FASTA (ccds) for
pFN21AE3075
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3075, 235 aa
1>>>pF1KE3075 235 - 235 aa - 235 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7163+/-0.000807; mu= 11.2443+/- 0.048
mean_var=58.6098+/-11.496, 0's: 0 Z-trim(106.3): 15 B-trim: 32 in 1/48
Lambda= 0.167529
statistics sampled from 8920 (8932) to 8920 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.274), width: 16
Scan time: 2.190
The best scores are: opt bits E(32554)
CCDS13671.1 FAM3B gene_id:54097|Hs108|chr21 ( 235) 1580 390.1 6.8e-109
CCDS42930.1 FAM3B gene_id:54097|Hs108|chr21 ( 187) 1244 308.8 1.5e-84
CCDS76060.1 FAM3A gene_id:60343|Hs108|chrX ( 244) 509 131.2 5.9e-31
CCDS35453.1 FAM3A gene_id:60343|Hs108|chrX ( 230) 507 130.7 7.8e-31
CCDS5782.1 FAM3C gene_id:10447|Hs108|chr7 ( 227) 501 129.3 2.1e-30
CCDS55542.1 FAM3A gene_id:60343|Hs108|chrX ( 192) 497 128.3 3.5e-30
CCDS2893.1 FAM3D gene_id:131177|Hs108|chr3 ( 224) 464 120.3 1e-27
>>CCDS13671.1 FAM3B gene_id:54097|Hs108|chr21 (235 aa)
initn: 1580 init1: 1580 opt: 1580 Z-score: 2068.5 bits: 390.1 E(32554): 6.8e-109
Smith-Waterman score: 1580; 100.0% identity (100.0% similar) in 235 aa overlap (1-235:1-235)
10 20 30 40 50 60
pF1KE3 MRPLAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRSIGERPVLKAPVPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MRPLAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRSIGERPVLKAPVPKR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIR
130 140 150 160 170 180
190 200 210 220 230
pF1KE3 NMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS
190 200 210 220 230
>>CCDS42930.1 FAM3B gene_id:54097|Hs108|chr21 (187 aa)
initn: 1244 init1: 1244 opt: 1244 Z-score: 1631.3 bits: 308.8 E(32554): 1.5e-84
Smith-Waterman score: 1244; 98.4% identity (98.9% similar) in 186 aa overlap (50-235:2-187)
20 30 40 50 60 70
pF1KE3 CAWYSGYLLAELIPDAPLSSAAYSIRSIGERPVLKAPVPKRQKCDHWTPCPSDTYAYRLL
::. :::::::::::::::::::::::::
CCDS42 MRPLAGAPVPKRQKCDHWTPCPSDTYAYRLL
10 20 30
80 90 100 110 120 130
pF1KE3 SGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMT
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 KFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFRSSWVFIAAKGLELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFRSSWVFIAAKGLELP
100 110 120 130 140 150
200 210 220 230
pF1KE3 SEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS
::::::::::::::::::::::::::::::::::::
CCDS42 SEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS
160 170 180
>>CCDS76060.1 FAM3A gene_id:60343|Hs108|chrX (244 aa)
initn: 492 init1: 248 opt: 509 Z-score: 669.2 bits: 131.2 E(32554): 5.9e-31
Smith-Waterman score: 509; 37.1% identity (68.6% similar) in 210 aa overlap (26-235:38-242)
10 20 30 40 50
pF1KE3 MRPLAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRSIGERPVLKA
:::. .:: : .: . . : : :
CCDS76 PGWAWQWLSSHPATLHQLECSGAISVHCNLYLLGSSDSSAPASRVAET--TGPESSVTAA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 PVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVN
: .. :: ::: . :.:..::.. :::.::..::. ::.::.:::.::
CCDS76 PRARKYKCGLPQPCPEEHLAFRVVSGAANVIGPKICLEDKMLMSSVKDNVGRGLNIALVN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 YVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALG
:.:.. .: :::. :: . . :::. .:.:...::: .:..:..... . ::
CCDS76 GVSGELIEARAFDMWAGDVND-LLKFIRPLHEGTLVFVASYDDPATKMNEETRKLFSELG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 SKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS
:.. ... ::.::::..:::.. : .... : . ..:.: ::: ...:::::.. .
CCDS76 SRNAKELAFRDSWVFVGAKGVQNKSPFEQHVKN--SKHSNKYEGWPEALEMEGCIPRRST
190 200 210 220 230 240
CCDS76 AS
>>CCDS35453.1 FAM3A gene_id:60343|Hs108|chrX (230 aa)
initn: 497 init1: 248 opt: 507 Z-score: 667.0 bits: 130.7 E(32554): 7.8e-31
Smith-Waterman score: 507; 35.4% identity (68.4% similar) in 237 aa overlap (1-235:1-228)
10 20 30 40 50
pF1KE3 MRPLAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSS--AAYSIRSIGERPVLKAPVP
:: ::: : ::.:: ... .: ... .. .: :. .. . : : ::
CCDS35 MR-LAGPLRIVVLVVSVGV-TW----IVVSILLGGPGSGFPRIQQLFTSPESSVTAAPRA
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 KRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVT
.. :: ::: . :.:..::.. :::.::..::. ::.::.:::.:: :.
CCDS35 RKYKCGLPQPCPEEHLAFRVVSGAANVIGPKICLEDKMLMSSVKDNVGRGLNIALVNGVS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 GNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKE
:.. .: :::. :: . . :::. .:.:...::: .:..:..... . :::..
CCDS35 GELIEARAFDMWAGD-VNDLLKFIRPLHEGTLVFVASYDDPATKMNEETRKLFSELGSRN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 IRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS
... ::.::::..:::.. : .. .....: ..:.: ::: ...:::::.. .
CCDS35 AKELAFRDSWVFVGAKGVQNKSPFE-QHVKNSK-HSNKYEGWPEALEMEGCIPRRSTAS
180 190 200 210 220 230
>>CCDS5782.1 FAM3C gene_id:10447|Hs108|chr7 (227 aa)
initn: 437 init1: 221 opt: 501 Z-score: 659.3 bits: 129.3 E(32554): 2.1e-30
Smith-Waterman score: 501; 36.8% identity (65.8% similar) in 228 aa overlap (7-234:5-226)
10 20 30 40 50 60
pF1KE3 MRPLAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRSIGERPVLKAPVPKR
: :.: .: . : ..: . :. :: :.. :: . . .. : :
CCDS57 MRVAGAAKLVVAVAVFLLTFYVISQVFEIKMDASLGN--LFARSALDTAA-RSTKPPR
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 QKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGN
:: :: .:... ::.. :::.:::.::. .::.::::.:..: ::.
CCDS57 YKCGISKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 VTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIR
: :. :::. :: .:. .:... ....: :::::.:.::..:. : ::: :
CCDS57 VLDTKYFDMWGGD-VAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSIT
120 130 140 150 160 170
190 200 210 220 230
pF1KE3 NMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS
:. ::..::: ..::.. : .... :..:. :.: ::: ...:::::...
CCDS57 NLGFRDNWVFCGGKGIKTKSPFEQHIKNNKDT--NKYEGWPEVVEMEGCIPQKQD
180 190 200 210 220
>>CCDS55542.1 FAM3A gene_id:60343|Hs108|chrX (192 aa)
initn: 475 init1: 248 opt: 497 Z-score: 655.3 bits: 128.3 E(32554): 3.5e-30
Smith-Waterman score: 497; 37.8% identity (71.0% similar) in 193 aa overlap (44-235:1-190)
20 30 40 50 60 70
pF1KE3 VVFASLCAWYSGYLLAELIPDAPLSSAAYSIRSIG-ERPVLKAPVPKRQKCDHWTPCPSD
.: : : : :: .. :: ::: .
CCDS55 MRLAGPESSVTAAPRARKYKCGLPQPCPEE
10 20 30
80 90 100 110 120 130
pF1KE3 TYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTATRCFDMYEG
:.:..::.. :::.::..::. ::.::.:::.:: :.:.. .: :::. :
CCDS55 HLAFRVVSGAANVIGPKICLEDKMLMSSVKDNVGRGLNIALVNGVSGELIEARAFDMWAG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 DNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFRSSWVFIA
: . . :::. .:.:...::: .:..:..... . :::.. ... ::.::::..
CCDS55 DVND-LLKFIRPLHEGTLVFVASYDDPATKMNEETRKLFSELGSRNAKELAFRDSWVFVG
100 110 120 130 140
200 210 220 230
pF1KE3 AKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS
:::.. : .. .....: ..:.: ::: ...:::::.. .
CCDS55 AKGVQNKSPFE-QHVKNSK-HSNKYEGWPEALEMEGCIPRRSTAS
150 160 170 180 190
>>CCDS2893.1 FAM3D gene_id:131177|Hs108|chr3 (224 aa)
initn: 430 init1: 232 opt: 464 Z-score: 611.1 bits: 120.3 E(32554): 1e-27
Smith-Waterman score: 464; 32.9% identity (64.9% similar) in 228 aa overlap (7-231:5-220)
10 20 30 40 50
pF1KE3 MRPLAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRS---IGERPVLKAPV
:.:... ..:: . .: .. . .: . .:: .. :. . :
CCDS28 MRVSGVLRLLALIFAIVTTW--------MFIRSYMSFSMKTIRLPRWLAASPTKEIQV
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 PKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYV
:. :: :::.. .:... ::.. .:::: ..:. .::.::.:::.:: .
CCDS28 -KKYKCGLIKPCPANYFAFKICSGAANVVGPTMCFEDRMIMSPVKNNVGRGLNIALVNGT
60 70 80 90 100
120 130 140 150 160 170
pF1KE3 TGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSK
:: : . . :::: :: ..::.. .:.....::: .:..:..... . :::.
CCDS28 TGAVLGQKAFDMYSGDVMH-LVKFLKEIPGGALVLVASYDDPGTKMNDESRKLFSDLGSS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE3 EIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS
... ::.:::::.:: :. : ... : :. :.: ::: ...:::.:
CCDS28 YAKQLGFRDSWVFIGAKDLRGKSPFEQFLKNSPDT--NKYEGWPELLEMEGCMPPKPF
170 180 190 200 210 220
235 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:26:33 2016 done: Sun Nov 6 04:26:33 2016
Total Scan time: 2.190 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]