Result of FASTA (omim) for
pFN21AE3510
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3510, 403 aa
1>>>pF1KE3510 403 - 403 aa - 403 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4044+/-0.000335; mu= 16.6470+/- 0.021
mean_var=72.6755+/-14.618, 0's: 0 Z-trim(115.2): 53 B-trim: 150 in 2/53
Lambda= 0.150446
statistics sampled from 25523 (25576) to 25523 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.3), width: 16
Scan time: 8.510
The best scores are: opt bits E(85289)
NP_653229 (OMIM: 611663,615663) TBC1 domain family ( 403) 2683 591.6 1.2e-168
XP_005260718 (OMIM: 611663,615663) PREDICTED: TBC1 ( 403) 2683 591.6 1.2e-168
XP_016883134 (OMIM: 611663,615663) PREDICTED: TBC1 ( 341) 2113 467.8 1.8e-131
XP_006723603 (OMIM: 611663,615663) PREDICTED: TBC1 ( 341) 2113 467.8 1.8e-131
NP_001161694 (OMIM: 616659) TBC1 domain family mem ( 615) 174 47.1 0.00014
NP_078958 (OMIM: 616659) TBC1 domain family member ( 648) 174 47.1 0.00015
XP_016857774 (OMIM: 602942) PREDICTED: ecotropic v ( 741) 169 46.1 0.00034
XP_016857772 (OMIM: 602942) PREDICTED: ecotropic v ( 785) 169 46.1 0.00036
XP_016857771 (OMIM: 602942) PREDICTED: ecotropic v ( 812) 168 45.9 0.00043
NP_001278391 (OMIM: 610810) TBC1 domain family mem ( 549) 155 43.0 0.0022
XP_005276971 (OMIM: 610810) PREDICTED: TBC1 domain ( 610) 155 43.0 0.0024
XP_011523477 (OMIM: 610811) PREDICTED: TBC1 domain ( 559) 153 42.5 0.003
XP_011523478 (OMIM: 610811) PREDICTED: TBC1 domain ( 390) 151 42.0 0.0031
NP_115634 (OMIM: 610809) TBC1 domain family member ( 549) 151 42.1 0.004
XP_006722118 (OMIM: 610811) PREDICTED: TBC1 domain ( 549) 151 42.1 0.004
NP_001116864 (OMIM: 610811) TBC1 domain family mem ( 549) 151 42.1 0.004
XP_011523474 (OMIM: 610811) PREDICTED: TBC1 domain ( 610) 151 42.1 0.0044
XP_011523475 (OMIM: 610811) PREDICTED: TBC1 domain ( 610) 151 42.1 0.0044
XP_011522361 (OMIM: 604334) PREDICTED: ubiquitin c ( 786) 151 42.2 0.0054
XP_016880135 (OMIM: 610806) PREDICTED: TBC1 domain ( 559) 149 41.7 0.0055
XP_006721971 (OMIM: 610806) PREDICTED: TBC1 domain ( 390) 147 41.1 0.0056
XP_016858483 (OMIM: 609238) PREDICTED: rab GTPase- ( 778) 150 42.0 0.0062
XP_006722317 (OMIM: 610808) PREDICTED: TBC1 domain ( 549) 148 41.4 0.0063
NP_001278395 (OMIM: 610808) TBC1 domain family mem ( 549) 148 41.4 0.0063
XP_011522360 (OMIM: 604334) PREDICTED: ubiquitin c (1031) 151 42.3 0.0067
NP_001116863 (OMIM: 607741) TBC1 domain family mem ( 549) 147 41.2 0.0074
NP_001001418 (OMIM: 610806) TBC1 domain family mem ( 549) 147 41.2 0.0074
XP_006721967 (OMIM: 610806) PREDICTED: TBC1 domain ( 610) 147 41.2 0.008
XP_011523116 (OMIM: 610806) PREDICTED: TBC1 domain ( 610) 147 41.2 0.008
XP_011522353 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 151 42.3 0.0087
NP_004496 (OMIM: 604334) ubiquitin carboxyl-termin (1406) 151 42.3 0.0087
XP_011522354 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 151 42.3 0.0087
XP_011522357 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 151 42.3 0.0087
XP_016880779 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 151 42.3 0.0087
XP_011522358 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 151 42.3 0.0087
NP_001291213 (OMIM: 604334) ubiquitin carboxyl-ter (1406) 151 42.3 0.0087
XP_011522352 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 151 42.3 0.0087
XP_011522356 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 151 42.3 0.0087
XP_011522355 (OMIM: 604334) PREDICTED: ubiquitin c (1406) 151 42.3 0.0087
XP_011545761 (OMIM: 610806) PREDICTED: TBC1 domain ( 559) 146 41.0 0.0087
>>NP_653229 (OMIM: 611663,615663) TBC1 domain family mem (403 aa)
initn: 2683 init1: 2683 opt: 2683 Z-score: 3149.1 bits: 591.6 E(85289): 1.2e-168
Smith-Waterman score: 2683; 100.0% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KE3 MALRSAQGDGPTSGHWDGGAEKADFNAKRKKKVAEIHQALNSDPTDVAALRRMAISEGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 MALRSAQGDGPTSGHWDGGAEKADFNAKRKKKVAEIHQALNSDPTDVAALRRMAISEGGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LTDEIRRKVWPKLLNVNANDPPPISGKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 LTDEIRRKVWPKLLNVNANDPPPISGKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQRE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLQEELIDIILLILERNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 GLQEELIDIILLILERNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TMDNTKHILNYLMPIIDQVNPELHDFMQSAEVGTIFALSWLITWFGHVLSDFRHVVRLYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 TMDNTKHILNYLMPIIDQVNPELHDFMQSAEVGTIFALSWLITWFGHVLSDFRHVVRLYD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 FFLACHPLMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 FFLACHPLMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QFPPSELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 QFPPSELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLT
310 320 330 340 350 360
370 380 390 400
pF1KE3 KPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQLFP
:::::::::::::::::::::::::::::::::::::::::::
NP_653 KPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQLFP
370 380 390 400
>>XP_005260718 (OMIM: 611663,615663) PREDICTED: TBC1 dom (403 aa)
initn: 2683 init1: 2683 opt: 2683 Z-score: 3149.1 bits: 591.6 E(85289): 1.2e-168
Smith-Waterman score: 2683; 100.0% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KE3 MALRSAQGDGPTSGHWDGGAEKADFNAKRKKKVAEIHQALNSDPTDVAALRRMAISEGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MALRSAQGDGPTSGHWDGGAEKADFNAKRKKKVAEIHQALNSDPTDVAALRRMAISEGGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LTDEIRRKVWPKLLNVNANDPPPISGKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTDEIRRKVWPKLLNVNANDPPPISGKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQRE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLQEELIDIILLILERNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLQEELIDIILLILERNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TMDNTKHILNYLMPIIDQVNPELHDFMQSAEVGTIFALSWLITWFGHVLSDFRHVVRLYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TMDNTKHILNYLMPIIDQVNPELHDFMQSAEVGTIFALSWLITWFGHVLSDFRHVVRLYD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 FFLACHPLMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FFLACHPLMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QFPPSELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QFPPSELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLT
310 320 330 340 350 360
370 380 390 400
pF1KE3 KPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQLFP
:::::::::::::::::::::::::::::::::::::::::::
XP_005 KPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQLFP
370 380 390 400
>>XP_016883134 (OMIM: 611663,615663) PREDICTED: TBC1 dom (341 aa)
initn: 2113 init1: 2113 opt: 2113 Z-score: 2481.5 bits: 467.8 E(85289): 1.8e-131
Smith-Waterman score: 2142; 84.6% identity (84.6% similar) in 403 aa overlap (1-403:1-341)
10 20 30 40 50 60
pF1KE3 MALRSAQGDGPTSGHWDGGAEKADFNAKRKKKVAEIHQALNSDPTDVAALRRMAISEGGL
:::::::::::::::::::::::
XP_016 MALRSAQGDGPTSGHWDGGAEKA-------------------------------------
10 20
70 80 90 100 110 120
pF1KE3 LTDEIRRKVWPKLLNVNANDPPPISGKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQRE
:::::::::::::::::::::::::::::::::::
XP_016 -------------------------GKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQRE
30 40 50
130 140 150 160 170 180
pF1KE3 GLQEELIDIILLILERNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLQEELIDIILLILERNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDP
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE3 TMDNTKHILNYLMPIIDQVNPELHDFMQSAEVGTIFALSWLITWFGHVLSDFRHVVRLYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMDNTKHILNYLMPIIDQVNPELHDFMQSAEVGTIFALSWLITWFGHVLSDFRHVVRLYD
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE3 FFLACHPLMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFLACHPLMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFV
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE3 QFPPSELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QFPPSELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLT
240 250 260 270 280 290
370 380 390 400
pF1KE3 KPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQLFP
:::::::::::::::::::::::::::::::::::::::::::
XP_016 KPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQLFP
300 310 320 330 340
>>XP_006723603 (OMIM: 611663,615663) PREDICTED: TBC1 dom (341 aa)
initn: 2113 init1: 2113 opt: 2113 Z-score: 2481.5 bits: 467.8 E(85289): 1.8e-131
Smith-Waterman score: 2142; 84.6% identity (84.6% similar) in 403 aa overlap (1-403:1-341)
10 20 30 40 50 60
pF1KE3 MALRSAQGDGPTSGHWDGGAEKADFNAKRKKKVAEIHQALNSDPTDVAALRRMAISEGGL
:::::::::::::::::::::::
XP_006 MALRSAQGDGPTSGHWDGGAEKA-------------------------------------
10 20
70 80 90 100 110 120
pF1KE3 LTDEIRRKVWPKLLNVNANDPPPISGKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQRE
:::::::::::::::::::::::::::::::::::
XP_006 -------------------------GKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQRE
30 40 50
130 140 150 160 170 180
pF1KE3 GLQEELIDIILLILERNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLQEELIDIILLILERNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDP
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE3 TMDNTKHILNYLMPIIDQVNPELHDFMQSAEVGTIFALSWLITWFGHVLSDFRHVVRLYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TMDNTKHILNYLMPIIDQVNPELHDFMQSAEVGTIFALSWLITWFGHVLSDFRHVVRLYD
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE3 FFLACHPLMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FFLACHPLMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFV
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE3 QFPPSELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QFPPSELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLT
240 250 260 270 280 290
370 380 390 400
pF1KE3 KPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQLFP
:::::::::::::::::::::::::::::::::::::::::::
XP_006 KPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQLFP
300 310 320 330 340
>>NP_001161694 (OMIM: 616659) TBC1 domain family member (615 aa)
initn: 76 init1: 51 opt: 174 Z-score: 203.3 bits: 47.1 E(85289): 0.00014
Smith-Waterman score: 174; 24.6% identity (55.6% similar) in 207 aa overlap (102-302:345-545)
80 90 100 110 120
pF1KE3 KLLNVNANDPPPISGKNLRQMSKDYQQVLLDVRRSLR--RFPPGMPEEQREGLQEELIDI
:: :. : .: : ::. :: : ::
NP_001 FRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEG-PENPGLGL---LNDI
320 330 340 350 360 370
130 140 150 160 170 180
pF1KE3 ILLILERNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDPTMDNTKHIL
.: . .: : ::. :.. .: :. ... . . .. .. .... :. :
NP_001 LLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQL
380 390 400 410 420 430
190 200 210 220 230 240
pF1KE3 NYLMPIIDQVNPELHDFMQSAEVGTI-FALSWLITWFGHVLSDFRHVVRLYDFFLACHP-
. :. .. ..: : ::..: . :.. : . ::. :: . . : :.::.. . . :
NP_001 GRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFP-FPDVLRLWEVLWTGLPG
440 450 460 470 480
250 260 270 280 290 300
pF1KE3 --LMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFVQFPPS
: . :.. . :. .:. . ..:. ... . : : ...:: : :.
NP_001 PNLHLLVACAILDMERDTLMLSGFGSNEILKHI-NELTMKLSVEDVLTRAEALHRQLTAC
490 500 510 520 530 540
310 320 330 340 350 360
pF1KE3 ELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLTKPRTN
NP_001 PELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDSSLEILPEE
550 560 570 580 590 600
>>NP_078958 (OMIM: 616659) TBC1 domain family member 17 (648 aa)
initn: 76 init1: 51 opt: 174 Z-score: 202.9 bits: 47.1 E(85289): 0.00015
Smith-Waterman score: 174; 24.6% identity (55.6% similar) in 207 aa overlap (102-302:378-578)
80 90 100 110 120
pF1KE3 KLLNVNANDPPPISGKNLRQMSKDYQQVLLDVRRSLR--RFPPGMPEEQREGLQEELIDI
:: :. : .: : ::. :: : ::
NP_078 FRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEG-PENPGLGL---LNDI
350 360 370 380 390 400
130 140 150 160 170 180
pF1KE3 ILLILERNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDPTMDNTKHIL
.: . .: : ::. :.. .: :. ... . . .. .. .... :. :
NP_078 LLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQL
410 420 430 440 450 460
190 200 210 220 230 240
pF1KE3 NYLMPIIDQVNPELHDFMQSAEVGTI-FALSWLITWFGHVLSDFRHVVRLYDFFLACHP-
. :. .. ..: : ::..: . :.. : . ::. :: . . : :.::.. . . :
NP_078 GRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFP-FPDVLRLWEVLWTGLPG
470 480 490 500 510 520
250 260 270 280 290 300
pF1KE3 --LMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFVQFPPS
: . :.. . :. .:. . ..:. ... . : : ...:: : :.
NP_078 PNLHLLVACAILDMERDTLMLSGFGSNEILKHI-NELTMKLSVEDVLTRAEALHRQLTAC
530 540 550 560 570 580
310 320 330 340 350 360
pF1KE3 ELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLTKPRTN
NP_078 PELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDSSLEILPEE
590 600 610 620 630 640
>>XP_016857774 (OMIM: 602942) PREDICTED: ecotropic viral (741 aa)
initn: 68 init1: 42 opt: 169 Z-score: 196.2 bits: 46.1 E(85289): 0.00034
Smith-Waterman score: 169; 22.6% identity (55.4% similar) in 381 aa overlap (2-366:58-420)
10 20 30
pF1KE3 MALRSAQGDGPTSGHWDGGAEKADFNAKRKK
.:::..:. .:: .. .:. : .. .
XP_016 PSSPSQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLE
30 40 50 60 70 80
40 50 60 70 80
pF1KE3 KVAEIHQA-LNSDPTDVAALRRMAISE---GGLLTDEIRRKVWPKLLNVNANDPPPISGK
. . : . . .. :: .. ..: :. ..: :: .:: . : . .
XP_016 EDSWILWGRIVNEWEDVRKKKEKQVKELVHKGI-PHHFRAIVW-QLLCSAQSMPIKDQYS
90 100 110 120 130 140
90 100 110 120 130 140
pF1KE3 NLRQMSKDYQQVLLDVRRSL-RRFPPGMPEEQREGL-QEELIDIILLILERNPQLHYYQG
.: .:.. ... .::.. : .: .....: :: :.... . .. : ::
XP_016 ELLKMTSPCEKL---IRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQG
150 160 170 180 190 200
150 160 170 180 190 200
pF1KE3 YHDIVVTFLLVVGERLATSLVEKL-STHHLRDFMDPTMDNTKHILNYLMPIIDQVNPELH
:: .:. . :. : . :: . ..::... :.: . . . .:.. :::
XP_016 SAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELF
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE3 DFMQSAEVGT-IFALSWLITWFGHVLSDFRHVV--RLYDFFLACHPLMPIYFAAVIVLYR
.:: : ..: ::..: : :. : . :..:.:.. . : .. ... .:
XP_016 VHFQSQSFHTSMYASSWFLTIF---LTTFPLPIATRIFDIFMS-EGLEIVFRVGLALLQM
270 280 290 300 310
270 280 290 300 310
pF1KE3 EQ-EVLDCDCDMASVHHLLSQIPQ--DLPYETLISRAGDLFVQFPPSELAREAAAQQQAE
.: :... : . . ..:. . ::. : . ::. : . :.. ... . . :
XP_016 NQAELMQLDME-GMLQHFQKVIPHQFDGVPDKLIQAAYQ--VKYNSKKMKK-----LEKE
320 330 340 350 360 370
320 330 340 350 360 370
pF1KE3 RTAASTFKDFELASAQQR---PDMVLRQRFRGLLRPEDRTKDVLTKPRTNRFVKLAVMGL
:. .: :..: .: . .:.::.. : . : : . ...:
XP_016 YTTIKT-KEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYL
380 390 400 410 420
380 390 400
pF1KE3 TVALGAAALAVVKSALEWAPKFQLQLFP
XP_016 IKRELATIKQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQARLS
430 440 450 460 470 480
>>XP_016857772 (OMIM: 602942) PREDICTED: ecotropic viral (785 aa)
initn: 68 init1: 42 opt: 169 Z-score: 195.8 bits: 46.1 E(85289): 0.00036
Smith-Waterman score: 169; 22.6% identity (55.4% similar) in 381 aa overlap (2-366:102-464)
10 20 30
pF1KE3 MALRSAQGDGPTSGHWDGGAEKADFNAKRKK
.:::..:. .:: .. .:. : .. .
XP_016 PSSPSQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLE
80 90 100 110 120 130
40 50 60 70 80
pF1KE3 KVAEIHQA-LNSDPTDVAALRRMAISE---GGLLTDEIRRKVWPKLLNVNANDPPPISGK
. . : . . .. :: .. ..: :. ..: :: .:: . : . .
XP_016 EDSWILWGRIVNEWEDVRKKKEKQVKELVHKGI-PHHFRAIVW-QLLCSAQSMPIKDQYS
140 150 160 170 180
90 100 110 120 130 140
pF1KE3 NLRQMSKDYQQVLLDVRRSL-RRFPPGMPEEQREGL-QEELIDIILLILERNPQLHYYQG
.: .:.. ... .::.. : .: .....: :: :.... . .. : ::
XP_016 ELLKMTSPCEKL---IRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQG
190 200 210 220 230 240
150 160 170 180 190 200
pF1KE3 YHDIVVTFLLVVGERLATSLVEKL-STHHLRDFMDPTMDNTKHILNYLMPIIDQVNPELH
:: .:. . :. : . :: . ..::... :.: . . . .:.. :::
XP_016 SAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELF
250 260 270 280 290 300
210 220 230 240 250 260
pF1KE3 DFMQSAEVGT-IFALSWLITWFGHVLSDFRHVV--RLYDFFLACHPLMPIYFAAVIVLYR
.:: : ..: ::..: : :. : . :..:.:.. . : .. ... .:
XP_016 VHFQSQSFHTSMYASSWFLTIF---LTTFPLPIATRIFDIFMS-EGLEIVFRVGLALLQM
310 320 330 340 350 360
270 280 290 300 310
pF1KE3 EQ-EVLDCDCDMASVHHLLSQIPQ--DLPYETLISRAGDLFVQFPPSELAREAAAQQQAE
.: :... : . . ..:. . ::. : . ::. : . :.. ... . . :
XP_016 NQAELMQLDME-GMLQHFQKVIPHQFDGVPDKLIQAAYQ--VKYNSKKMKK-----LEKE
370 380 390 400 410
320 330 340 350 360 370
pF1KE3 RTAASTFKDFELASAQQR---PDMVLRQRFRGLLRPEDRTKDVLTKPRTNRFVKLAVMGL
:. .: :..: .: . .:.::.. : . : : . ...:
XP_016 YTTIKT-KEMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYL
420 430 440 450 460 470
380 390 400
pF1KE3 TVALGAAALAVVKSALEWAPKFQLQLFP
XP_016 IKRELATIKQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQARLS
480 490 500 510 520 530
>>XP_016857771 (OMIM: 602942) PREDICTED: ecotropic viral (812 aa)
initn: 68 init1: 42 opt: 168 Z-score: 194.5 bits: 45.9 E(85289): 0.00043
Smith-Waterman score: 168; 23.3% identity (55.3% similar) in 313 aa overlap (66-366:196-491)
40 50 60 70 80 90
pF1KE3 IHQALNSDPTDVAALRRMAISEGGLLTDEIRRKVWPKLLNVNANDPPPISGKNLRQMSKD
: :: .:: . : . ..: .:..
XP_016 HHSQLCRFQVHYLKRSHTEELVHKGIPHHFRAIVW-QLLCSAQSMPIKDQYSELLKMTSP
170 180 190 200 210 220
100 110 120 130 140 150
pF1KE3 YQQVLLDVRRSL-RRFPPGMPEEQREGL-QEELIDIILLILERNPQLHYYQGYHDIVVTF
... .::.. : .: .....: :: :.... . .. : :: :: .
XP_016 CEKL---IRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLL
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE3 LLVVGERLATSLVEKL-STHHLRDFMDPTMDNTKHILNYLMPIIDQVNPELHDFMQSAEV
:. . :. : . :: . ..::... :.: . . . .:.. ::: .::
XP_016 LMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELFVHFQSQSF
290 300 310 320 330 340
220 230 240 250 260
pF1KE3 GT-IFALSWLITWFGHVLSDFRHVV--RLYDFFLACHPLMPIYFAAVIVLYREQ-EVLDC
: ..: ::..: : :. : . :..:.:.. . : .. ... .: .: :...
XP_016 HTSMYASSWFLTIF---LTTFPLPIATRIFDIFMS-EGLEIVFRVGLALLQMNQAELMQL
350 360 370 380 390
270 280 290 300 310 320
pF1KE3 DCDMASVHHLLSQIPQ--DLPYETLISRAGDLFVQFPPSELAREAAAQQQAERTAASTFK
: . . ..:. . ::. : . ::. : . :.. ... . . : :. .: :
XP_016 DME-GMLQHFQKVIPHQFDGVPDKLIQAAYQ--VKYNSKKMKK-----LEKEYTTIKT-K
400 410 420 430 440
330 340 350 360 370 380
pF1KE3 DFELASAQQR---PDMVLRQRFRGLLRPEDRTKDVLTKPRTNRFVKLAVMGLTVALGAAA
..: .: . .:.::.. : . : : . ...:
XP_016 EMEEQVEIKRLRTENRLLKQRIETLEKESASLADRLIQGQVTRAQEAEENYLIKRELATI
450 460 470 480 490 500
390 400
pF1KE3 LAVVKSALEWAPKFQLQLFP
XP_016 KQQSDEASAKLEQAENTIRKLQHQQQWHKCSSNYNEDFVLQLEKELVQARLSEAESQCAL
510 520 530 540 550 560
>>NP_001278391 (OMIM: 610810) TBC1 domain family member (549 aa)
initn: 70 init1: 70 opt: 155 Z-score: 181.7 bits: 43.0 E(85289): 0.0022
Smith-Waterman score: 155; 26.1% identity (55.3% similar) in 199 aa overlap (65-251:106-300)
40 50 60 70 80
pF1KE3 EIHQALNSDPTDVAALRRMAISEGGLLTDEIRRKVWPKLLNVNA---NDPP--PISGKNL
:: .: :::.. ..: : ..
NP_001 SKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKG
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE3 RQMSKDYQQVLLDVRRSLRRFPPGMPEEQREGL-QEELIDIILLILERNPQLHYYQGYHD
.. :. :.. :. .::. : ..: : :.::. :.: : ::.. : .
NP_001 KRSSEHIQRIDRDISGTLRKH---MFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSH
140 150 160 170 180 190
150 160 170 180 190 200
pF1KE3 IVVTFLLVVGERLAT-SLVEKLST--HHLRDFMDPTMDNTKHILNYLMPIIDQVNPELHD
:.. ::: . :. : .::. :.. : :. : .:. ... . . .. .:.
NP_001 IAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMG
200 210 220 230 240 250
210 220 230 240 250 260
pF1KE3 FMQSAEV-GTIFALSWLITWFGHVLSDFRHVVRLYDFFLAC--HPLMPIYFAAVIVLYRE
... .. : :. :: . .: . ..::.: .:. . ::::
NP_001 HQDKKDLCGQCSPLGCLIRILIDGIS-LGLTLRLWDVYLVEGEQALMPITRIAFKVQQKR
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE3 QEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFVQFPPSELAREAAAQQQAERTAA
NP_001 LTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASR
320 330 340 350 360 370
403 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:34:35 2016 done: Sat Nov 5 22:34:36 2016
Total Scan time: 8.510 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]