Result of FASTA (omim) for
pFN21AE3224
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3224, 510 aa
1>>>pF1KE3224 510 - 510 aa - 510 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7740+/-0.000335; mu= 10.4900+/- 0.021
mean_var=215.2634+/-43.726, 0's: 0 Z-trim(122.7): 71 B-trim: 2008 in 1/57
Lambda= 0.087416
statistics sampled from 41242 (41315) to 41242 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.484), width: 16
Scan time: 9.630
The best scores are: opt bits E(85289)
NP_112506 (OMIM: 610924,615895) ranBP-type and C3H ( 510) 3657 473.6 5.9e-133
XP_005260702 (OMIM: 610924,615895) PREDICTED: ranB ( 527) 3613 468.1 2.8e-131
NP_006453 (OMIM: 610924,615895) ranBP-type and C3H ( 468) 3307 429.5 1.1e-119
XP_011527440 (OMIM: 610924,615895) PREDICTED: ranB ( 551) 3305 429.3 1.4e-119
XP_011527439 (OMIM: 610924,615895) PREDICTED: ranB ( 568) 3305 429.3 1.5e-119
XP_011527441 (OMIM: 610924,615895) PREDICTED: ranB ( 502) 2698 352.7 1.5e-96
XP_016883084 (OMIM: 610924,615895) PREDICTED: ranB ( 340) 1542 206.7 8.8e-53
NP_001310885 (OMIM: 610924,615895) ranBP-type and ( 340) 1542 206.7 8.8e-53
XP_016883083 (OMIM: 610924,615895) PREDICTED: ranB ( 340) 1542 206.7 8.8e-53
NP_001310887 (OMIM: 610924,615895) ranBP-type and ( 340) 1542 206.7 8.8e-53
XP_011527442 (OMIM: 610924,615895) PREDICTED: ranB ( 362) 1405 189.5 1.5e-47
XP_016869376 (OMIM: 611885) PREDICTED: sharpin iso ( 385) 422 65.5 3.2e-10
NP_112236 (OMIM: 611885) sharpin [Homo sapiens] ( 387) 419 65.1 4.1e-10
XP_016869377 (OMIM: 611885) PREDICTED: sharpin iso ( 326) 382 60.4 9.3e-09
NP_001310889 (OMIM: 610924,615895) ranBP-type and ( 105) 360 57.1 3e-08
XP_016867854 (OMIM: 212840,609948) PREDICTED: E3 u ( 488) 286 48.5 5.4e-05
XP_011513738 (OMIM: 212840,609948) PREDICTED: E3 u ( 488) 286 48.5 5.4e-05
XP_006710421 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 588) 286 48.6 6.1e-05
NP_001120833 (OMIM: 610872) E3 ubiquitin-protein l ( 587) 285 48.4 6.7e-05
XP_006710420 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 688) 286 48.6 6.8e-05
NP_699172 (OMIM: 610872) E3 ubiquitin-protein liga ( 732) 286 48.7 7.1e-05
XP_006710419 (OMIM: 610872) PREDICTED: E3 ubiquiti ( 732) 286 48.7 7.1e-05
NP_001287755 (OMIM: 610872) E3 ubiquitin-protein l ( 731) 285 48.5 7.8e-05
XP_016867852 (OMIM: 212840,609948) PREDICTED: E3 u ( 866) 286 48.7 8e-05
NP_996999 (OMIM: 212840,609948) E3 ubiquitin-prote ( 866) 286 48.7 8e-05
XP_005249842 (OMIM: 212840,609948) PREDICTED: E3 u ( 923) 286 48.8 8.3e-05
NP_996994 (OMIM: 212840,609948) E3 ubiquitin-prote ( 923) 286 48.8 8.3e-05
XP_011512731 (OMIM: 607489) PREDICTED: cullin-9 is (1834) 257 45.4 0.0017
XP_016866079 (OMIM: 607489) PREDICTED: cullin-9 is (1909) 257 45.5 0.0017
XP_011512729 (OMIM: 607489) PREDICTED: cullin-9 is (2095) 257 45.5 0.0018
XP_011512728 (OMIM: 607489) PREDICTED: cullin-9 is (2339) 257 45.5 0.002
XP_011512727 (OMIM: 607489) PREDICTED: cullin-9 is (2456) 257 45.6 0.002
NP_055904 (OMIM: 607489) cullin-9 [Homo sapiens] (2517) 257 45.6 0.0021
XP_011512726 (OMIM: 607489) PREDICTED: cullin-9 is (2539) 257 45.6 0.0021
XP_011512725 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 257 45.6 0.0021
XP_011512724 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 257 45.6 0.0021
XP_016866078 (OMIM: 607489) PREDICTED: cullin-9 is (2566) 257 45.6 0.0021
>>NP_112506 (OMIM: 610924,615895) ranBP-type and C3HC4-t (510 aa)
initn: 3657 init1: 3657 opt: 3657 Z-score: 2508.0 bits: 473.6 E(85289): 5.9e-133
Smith-Waterman score: 3657; 100.0% identity (100.0% similar) in 510 aa overlap (1-510:1-510)
10 20 30 40 50 60
pF1KE3 MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSVQLKPEVSPTQDIRLWVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSVQLKPEVSPTQDIRLWVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 VEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 QNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 PGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 PGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 AGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLREC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 AGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLREC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 LHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 AENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 AENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLAL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 RAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 RAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPR
430 440 450 460 470 480
490 500 510
pF1KE3 WGPGGPGDTSGGCRCRVNGIPCHPSCQNCH
::::::::::::::::::::::::::::::
NP_112 WGPGGPGDTSGGCRCRVNGIPCHPSCQNCH
490 500 510
>>XP_005260702 (OMIM: 610924,615895) PREDICTED: ranBP-ty (527 aa)
initn: 3613 init1: 3613 opt: 3613 Z-score: 2477.8 bits: 468.1 E(85289): 2.8e-131
Smith-Waterman score: 3613; 100.0% identity (100.0% similar) in 503 aa overlap (8-510:25-527)
10 20 30 40
pF1KE3 MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSV
::::::::::::::::::::::::::::::::::::
XP_005 MDEKTKKAPENKPCANWLLLYWLSAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 QLKPEVSPTQDIRLWVSVEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLKPEVSPTQDIRLWVSVEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVI
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 GQRLARDQETLHSHGVRQNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQRLARDQETLHSHGVRQNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQ
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 PRGPLEPGPPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRGPLEPGPPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEA
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 YQVPASYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YQVPASYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECP
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 VCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKA
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 LLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCK
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 AIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWI
430 440 450 460 470 480
470 480 490 500 510
pF1KE3 RCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH
490 500 510 520
>>NP_006453 (OMIM: 610924,615895) ranBP-type and C3HC4-t (468 aa)
initn: 3305 init1: 3305 opt: 3307 Z-score: 2269.9 bits: 429.5 E(85289): 1.1e-119
Smith-Waterman score: 3307; 98.5% identity (98.9% similar) in 464 aa overlap (47-510:6-468)
20 30 40 50 60 70
pF1KE3 RAVAGGDEQVAMKCAIWLAEQRVPLSVQLKPEVSPTQDIRLWVSVEDAQMHTVTIWLTVR
:. :. :::::::::::::::::::::
NP_006 MGTATPDGREDQE-RLWVSVEDAQMHTVTIWLTVR
10 20 30
80 90 100 110 120 130
pF1KE3 PDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVRQNGDSAYLYLLSARNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVRQNGDSAYLYLLSARNT
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 SLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPGRGQPDAVPEPPPVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPGRGQPDAVPEPPPVG
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE3 WQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAGEEEALRQYQQRKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 WQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAGEEEALRQYQQRKQQ
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE3 QQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNS
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE3 QEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDC
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE3 KGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLK
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE3 VMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCR
400 410 420 430 440 450
500 510
pF1KE3 VNGIPCHPSCQNCH
::::::::::::::
NP_006 VNGIPCHPSCQNCH
460
>>XP_011527440 (OMIM: 610924,615895) PREDICTED: ranBP-ty (551 aa)
initn: 3643 init1: 3298 opt: 3305 Z-score: 2267.7 bits: 429.3 E(85289): 1.4e-119
Smith-Waterman score: 3510; 92.4% identity (92.4% similar) in 542 aa overlap (10-510:10-551)
10 20 30 40 50
pF1KE3 MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSVQLKPEVSPTQDIR----
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSVQLKPEVSPTQDIRSRGE
10 20 30 40 50 60
60 70
pF1KE3 -------------------------------------LWVSVEDAQMHTVTIWLTVRPDM
:::::::::::::::::::::::
XP_011 KTEEVGEVREVPDHGGPRVLPRVDSKSSVEPLEGPNWLWVSVEDAQMHTVTIWLTVRPDM
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE3 TVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVRQNGDSAYLYLLSARNTSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVRQNGDSAYLYLLSARNTSLN
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE3 PQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPGRGQPDAVPEPPPVGWQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPGRGQPDAVPEPPPVGWQC
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE3 PGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAGEEEALRQYQQRKQQQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAGEEEALRQYQQRKQQQQE
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE3 GNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEA
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE3 EVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGW
370 380 390 400 410 420
380 390 400 410 420 430
pF1KE3 CFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVML
430 440 450 460 470 480
440 450 460 470 480 490
pF1KE3 QQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNG
490 500 510 520 530 540
500 510
pF1KE3 IPCHPSCQNCH
:::::::::::
XP_011 IPCHPSCQNCH
550
>>XP_011527439 (OMIM: 610924,615895) PREDICTED: ranBP-ty (568 aa)
initn: 3599 init1: 3298 opt: 3305 Z-score: 2267.5 bits: 429.3 E(85289): 1.5e-119
Smith-Waterman score: 3510; 92.4% identity (92.4% similar) in 542 aa overlap (10-510:27-568)
10 20 30 40
pF1KE3 MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSV
::::::::::::::::::::::::::::::::::
XP_011 MDEKTKKAPENKPCANWLLLYWLSAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSV
10 20 30 40 50 60
50 60
pF1KE3 QLKPEVSPTQDIR-----------------------------------------LWVSVE
::::::::::::: ::::::
XP_011 QLKPEVSPTQDIRSRGEKTEEVGEVREVPDHGGPRVLPRVDSKSSVEPLEGPNWLWVSVE
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE3 DAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVRQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVRQN
130 140 150 160 170 180
130 140 150 160 170 180
pF1KE3 GDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPG
190 200 210 220 230 240
190 200 210 220 230 240
pF1KE3 RGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAG
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE3 EEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLH
310 320 330 340 350 360
310 320 330 340 350 360
pF1KE3 TFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAE
370 380 390 400 410 420
370 380 390 400 410 420
pF1KE3 NRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRA
430 440 450 460 470 480
430 440 450 460 470 480
pF1KE3 QNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWG
490 500 510 520 530 540
490 500 510
pF1KE3 PGGPGDTSGGCRCRVNGIPCHPSCQNCH
::::::::::::::::::::::::::::
XP_011 PGGPGDTSGGCRCRVNGIPCHPSCQNCH
550 560
>>XP_011527441 (OMIM: 610924,615895) PREDICTED: ranBP-ty (502 aa)
initn: 2992 init1: 2691 opt: 2698 Z-score: 1854.4 bits: 352.7 E(85289): 1.5e-96
Smith-Waterman score: 2903; 91.2% identity (91.2% similar) in 468 aa overlap (10-436:27-494)
10 20 30 40
pF1KE3 MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSV
::::::::::::::::::::::::::::::::::
XP_011 MDEKTKKAPENKPCANWLLLYWLSAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSV
10 20 30 40 50 60
50 60
pF1KE3 QLKPEVSPTQDIR-----------------------------------------LWVSVE
::::::::::::: ::::::
XP_011 QLKPEVSPTQDIRSRGEKTEEVGEVREVPDHGGPRVLPRVDSKSSVEPLEGPNWLWVSVE
70 80 90 100 110 120
70 80 90 100 110 120
pF1KE3 DAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVRQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVRQN
130 140 150 160 170 180
130 140 150 160 170 180
pF1KE3 GDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPG
190 200 210 220 230 240
190 200 210 220 230 240
pF1KE3 RGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAG
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE3 EEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLH
310 320 330 340 350 360
310 320 330 340 350 360
pF1KE3 TFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAE
370 380 390 400 410 420
370 380 390 400 410 420
pF1KE3 NRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRA
430 440 450 460 470 480
430 440 450 460 470 480
pF1KE3 QNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWG
::::::::::::::
XP_011 QNDVAARQTTEMLKGQHLPHSR
490 500
>>XP_016883084 (OMIM: 610924,615895) PREDICTED: ranBP-ty (340 aa)
initn: 1530 init1: 1530 opt: 1542 Z-score: 1068.6 bits: 206.7 E(85289): 8.8e-53
Smith-Waterman score: 1542; 97.7% identity (98.6% similar) in 213 aa overlap (298-510:129-340)
270 280 290 300 310 320
pF1KE3 LDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFID
:.:. : ::::::::::::::::::::::
XP_016 CAAGRAPRPTRSPPHTSPTRRSERAWRARRRRCVST-SRECLQGTIRNSQEAEVSCPFID
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE3 NTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVN
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE3 EFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRC
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE3 PQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQ
280 290 300 310 320 330
510
pF1KE3 NCH
:::
XP_016 NCH
340
>>NP_001310885 (OMIM: 610924,615895) ranBP-type and C3HC (340 aa)
initn: 1530 init1: 1530 opt: 1542 Z-score: 1068.6 bits: 206.7 E(85289): 8.8e-53
Smith-Waterman score: 1542; 97.7% identity (98.6% similar) in 213 aa overlap (298-510:129-340)
270 280 290 300 310 320
pF1KE3 LDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFID
:.:. : ::::::::::::::::::::::
NP_001 CAAGRAPRPTRSPPHTSPTRRSERAWRARRRRCVST-SRECLQGTIRNSQEAEVSCPFID
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE3 NTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVN
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE3 EFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRC
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE3 PQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQ
280 290 300 310 320 330
510
pF1KE3 NCH
:::
NP_001 NCH
340
>>XP_016883083 (OMIM: 610924,615895) PREDICTED: ranBP-ty (340 aa)
initn: 1530 init1: 1530 opt: 1542 Z-score: 1068.6 bits: 206.7 E(85289): 8.8e-53
Smith-Waterman score: 1542; 97.7% identity (98.6% similar) in 213 aa overlap (298-510:129-340)
270 280 290 300 310 320
pF1KE3 LDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFID
:.:. : ::::::::::::::::::::::
XP_016 CAAGRAPRPTRSPPHTSPTRRSERAWRARRRRCVST-SRECLQGTIRNSQEAEVSCPFID
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE3 NTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVN
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE3 EFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRC
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE3 PQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQ
280 290 300 310 320 330
510
pF1KE3 NCH
:::
XP_016 NCH
340
>>NP_001310887 (OMIM: 610924,615895) ranBP-type and C3HC (340 aa)
initn: 1530 init1: 1530 opt: 1542 Z-score: 1068.6 bits: 206.7 E(85289): 8.8e-53
Smith-Waterman score: 1542; 97.7% identity (98.6% similar) in 213 aa overlap (298-510:129-340)
270 280 290 300 310 320
pF1KE3 LDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFID
:.:. : ::::::::::::::::::::::
NP_001 CAAGRAPRPTRSPPHTSPTRRSERAWRARRRRCVST-SRECLQGTIRNSQEAEVSCPFID
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE3 NTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVN
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE3 EFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRC
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE3 PQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQ
280 290 300 310 320 330
510
pF1KE3 NCH
:::
NP_001 NCH
340
510 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 13:10:45 2016 done: Sun Nov 6 13:10:46 2016
Total Scan time: 9.630 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]