FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1684, 196 aa
  1>>>pF1KE1684 196 - 196 aa - 196 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2394+/-0.000304; mu= 14.3048+/- 0.019
 mean_var=68.5959+/-13.571, 0's: 0 Z-trim(118.4): 23  B-trim: 916 in 1/54
 Lambda= 0.154855
 statistics sampled from 31367 (31390) to 31367 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.756), E-opt: 0.2 (0.368), width:  16
 Scan time:  6.310

The best scores are:                                      opt bits E(85289)
NP_742151 (OMIM: 607402,609532) interferon lambda- ( 196) 1321 303.3 1.7e-82
XP_005258822 (OMIM: 607402,609532) PREDICTED: inte ( 200) 1321 303.3 1.7e-82
NP_742150 (OMIM: 607401) interferon lambda-2 [Homo ( 200) 1268 291.4 6.3e-79
NP_742152 (OMIM: 607403) interferon lambda-1 precu ( 200)  899 209.0 4.1e-54
NP_001263183 (OMIM: 615090) interferon lambda-4 pr ( 179)  157 43.2  0.0003


>>NP_742151 (OMIM: 607402,609532) interferon lambda-3 pr  (196 aa)
 initn: 1321 init1: 1321 opt: 1321  Z-score: 1602.1  bits: 303.3 E(85289): 1.7e-82
Smith-Waterman score: 1321; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:1-196)

               10        20        30        40        50        60
pF1KE1 MTGDCMPVLVLMAAVLTVTGAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRAKDAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 MTGDCMPVLVLMAAVLTVTGAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRAKDAL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 EESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALGDVLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 EESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALGDVLD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 QPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTFNLFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 QPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTFNLFR
              130       140       150       160       170       180

              190      
pF1KE1 LLTRDLNCVASGDLCV
       ::::::::::::::::
NP_742 LLTRDLNCVASGDLCV
              190      

>>XP_005258822 (OMIM: 607402,609532) PREDICTED: interfer  (200 aa)
 initn: 1321 init1: 1321 opt: 1321  Z-score: 1602.0  bits: 303.3 E(85289): 1.7e-82
Smith-Waterman score: 1321; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:5-200)

                   10        20        30        40        50      
pF1KE1     MTGDCMPVLVLMAAVLTVTGAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRA
           ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKLDMTGDCMPVLVLMAAVLTVTGAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRA
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KE1 KDALEESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDALEESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALG
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KE1 DVLDQPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVLDQPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTF
              130       140       150       160       170       180

        180       190      
pF1KE1 NLFRLLTRDLNCVASGDLCV
       ::::::::::::::::::::
XP_005 NLFRLLTRDLNCVASGDLCV
              190       200

>>NP_742150 (OMIM: 607401) interferon lambda-2 [Homo sap  (200 aa)
 initn: 1268 init1: 1268 opt: 1268  Z-score: 1538.0  bits: 291.4 E(85289): 6.3e-79
Smith-Waterman score: 1268; 95.9% identity (99.0% similar) in 196 aa overlap (1-196:5-200)

                   10        20        30        40        50      
pF1KE1     MTGDCMPVLVLMAAVLTVTGAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRA
           ::::: :::::::::::::::::::::.::::::::::::::::::::::::::::
NP_742 MKLDMTGDCTPVLVLMAAVLTVTGAVPVARLHGALPDARGCHIAQFKSLSPQELQAFKRA
               10        20        30        40        50        60

         60        70        80        90       100       110      
pF1KE1 KDALEESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALG
       :::::::::::::.:.:::::::::::::::::::.::::::::::::::::::::::: 
NP_742 KDALEESLLLKDCRCHSRLFPRTWDLRQLQVRERPMALEAELALTLKVLEATADTDPALV
               70        80        90       100       110       120

        120       130       140       150       160       170      
pF1KE1 DVLDQPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTF
       ::::::::::::::::.::::::::::::::::::::::.::::::::::::::::::::
NP_742 DVLDQPLHTLHHILSQFRACIQPQPTAGPRTRGRLHHWLYRLQEAPKKESPGCLEASVTF
              130       140       150       160       170       180

        180       190      
pF1KE1 NLFRLLTRDLNCVASGDLCV
       ::::::::::::::::::::
NP_742 NLFRLLTRDLNCVASGDLCV
              190       200

>>NP_742152 (OMIM: 607403) interferon lambda-1 precursor  (200 aa)
 initn: 948 init1: 521 opt: 899  Z-score: 1092.5  bits: 209.0 E(85289): 4.1e-54
Smith-Waterman score: 899; 74.1% identity (86.8% similar) in 189 aa overlap (8-196:8-191)

               10        20        30        40        50        60
pF1KE1 MTGDCMPVLVLMAAVLTVTGAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRAKDAL
              ::: ..  :.:.: ::...       ..::::..::::::::: .::.:.:::
NP_742 MAAAWTVVLVTLVLGLAVAGPVPTSK---PTTTGKGCHIGRFKSLSPQELASFKKARDAL
               10        20           30        40        50       

               70        80        90       100       110       120
pF1KE1 EESLLLKDCKCRSRLFPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALGDVLD
       :::: ::. .: : .:: .:::: :::::::::::::::::::::::.:   ::: ::::
NP_742 EESLKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAG--PALEDVLD
        60        70        80        90       100         110     

              130       140       150       160       170       180
pF1KE1 QPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTFNLFR
       :::::::::::::.:::::::::::: ::::::::::::::::::: :::::::::::::
NP_742 QPLHTLHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTFNLFR
         120       130       140       150       160       170     

              190               
pF1KE1 LLTRDLNCVASGDLCV         
       ::::::. ::.:.::.         
NP_742 LLTRDLKYVADGNLCLRTSTHPEST
         180       190       200

>>NP_001263183 (OMIM: 615090) interferon lambda-4 precur  (179 aa)
 initn: 120 init1:  87 opt: 157  Z-score: 197.3  bits: 43.2 E(85289): 0.0003
Smith-Waterman score: 170; 28.3% identity (53.6% similar) in 166 aa overlap (35-196:25-179)

           10        20        30        40        50        60    
pF1KE1 CMPVLVLMAAVLTVTGAVPVARLRGALPDARGCHIAQFKSLSPQELQAFKRAKDALEESL
                                     : : .....:: :. : : :  .:  ::  
NP_001       MRPSVWAAVAAGLWVLCTVIAAAPRRCLLSHYRSLEPRTLAAAKALRDRYEEEA
                     10        20        30        40        50    

              70         80        90       100       110       120
pF1KE1 L---LKDCKCRSRL-FPRTWDLRQLQVRERPVALEAELALTLKVLEATADTDPALGDVLD
       :    ..:. : :   ::  .  .:.   : .: .:. .:.       ..  :. : .:.
NP_001 LSWGQRNCSFRPRRDPPRPSSCARLRHVARGIA-DAQAVLS---GLHRSELLPGAGPILE
           60        70        80         90          100       110

              130       140       150       160       170       180
pF1KE1 QPLHTLHHILSQLRACIQPQPTAGPRTRGRLHHWLHRLQEAPKKESPGCLEASVTFNLFR
            :     .. ::..    : : .  ..    .: ..  . .:: : .:::.:::.:
NP_001 ----LLAAAGRDVAACLE---LARPGSSRKVPGAQKRRHKPRRADSPRCRKASVVFNLLR
                  120          130       140       150       160   

              190      
pF1KE1 LLTRDLNCVASGDLCV
       ::: .:  .: .  :.
NP_001 LLTWELRLAAHSGPCL
           170         




196 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 15:26:07 2016 done: Mon Nov  7 15:26:08 2016
 Total Scan time:  6.310 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]