Result of FASTA (ccds) for
pFN21AE5319
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5319, 319 aa
1>>>pF1KE5319 319 - 319 aa - 319 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5901+/-0.000897; mu= 14.4360+/- 0.054
mean_var=65.3855+/-12.817, 0's: 0 Z-trim(105.7): 16 B-trim: 0 in 0/50
Lambda= 0.158611
statistics sampled from 8552 (8564) to 8552 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.263), width: 16
Scan time: 2.150
The best scores are: opt bits E(32554)
CCDS11795.1 PYCR1 gene_id:5831|Hs108|chr17 ( 319) 2033 473.9 7.2e-134
CCDS62366.1 PYCR1 gene_id:5831|Hs108|chr17 ( 346) 2033 473.9 7.7e-134
CCDS11794.1 PYCR1 gene_id:5831|Hs108|chr17 ( 316) 1860 434.3 5.9e-122
CCDS31043.1 PYCR2 gene_id:29920|Hs108|chr1 ( 320) 1742 407.3 8e-114
CCDS82221.1 PYCR1 gene_id:5831|Hs108|chr17 ( 217) 1359 319.6 1.4e-87
CCDS62365.1 PYCR1 gene_id:5831|Hs108|chr17 ( 288) 1149 271.6 5.1e-73
CCDS6407.2 PYCRL gene_id:65263|Hs108|chr8 ( 286) 768 184.4 8.9e-47
CCDS73039.1 PYCR2 gene_id:29920|Hs108|chr1 ( 246) 742 178.5 4.8e-45
>>CCDS11795.1 PYCR1 gene_id:5831|Hs108|chr17 (319 aa)
initn: 2033 init1: 2033 opt: 2033 Z-score: 2516.9 bits: 473.9 E(32554): 7.2e-134
Smith-Waterman score: 2033; 100.0% identity (100.0% similar) in 319 aa overlap (1-319:1-319)
10 20 30 40 50 60
pF1KE5 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL
250 260 270 280 290 300
310
pF1KE5 SPSGHTKLLPRSLAPAGKD
:::::::::::::::::::
CCDS11 SPSGHTKLLPRSLAPAGKD
310
>>CCDS62366.1 PYCR1 gene_id:5831|Hs108|chr17 (346 aa)
initn: 2033 init1: 2033 opt: 2033 Z-score: 2516.3 bits: 473.9 E(32554): 7.7e-134
Smith-Waterman score: 2033; 100.0% identity (100.0% similar) in 319 aa overlap (1-319:28-346)
10 20 30
pF1KE5 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMAS
:::::::::::::::::::::::::::::::::
CCDS62 MVGGGRRVGRDEPVPSVGALGQGSPDSMSVGFIGAGQLAFALAKGFTAAGVLAAHKIMAS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 SPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 SPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE5 SCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 SCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 SSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 SSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGA
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE5 AKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 AKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMAD
250 260 270 280 290 300
280 290 300 310
pF1KE5 QEQVSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD
::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 QEQVSPAAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD
310 320 330 340
>>CCDS11794.1 PYCR1 gene_id:5831|Hs108|chr17 (316 aa)
initn: 1842 init1: 1842 opt: 1860 Z-score: 2303.0 bits: 434.3 E(32554): 5.9e-122
Smith-Waterman score: 1860; 94.6% identity (95.3% similar) in 317 aa overlap (1-316:1-314)
10 20 30 40 50 60
pF1KE5 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL
::::::::::::::::::::::::::::::::::::::::::::::::: .: :
CCDS11 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKDHLPLELG---
250 260 270 280 290
310
pF1KE5 SPSG-HTKLLPRSLAPAGKD
:: : : :: .:: :
CCDS11 SPEGLHPLLLQYQLARAPS
300 310
>>CCDS31043.1 PYCR2 gene_id:29920|Hs108|chr1 (320 aa)
initn: 1742 init1: 1742 opt: 1742 Z-score: 2157.0 bits: 407.3 E(32554): 8e-114
Smith-Waterman score: 1742; 84.9% identity (95.0% similar) in 318 aa overlap (1-318:1-318)
10 20 30 40 50 60
pF1KE5 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
::::::::::::.:::.::::::.:.::::.::::.:.: ::::::::::.:: :::::
CCDS31 MSVGFIGAGQLAYALARGFTAAGILSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
.::::::::::::::::::::::::.. :::::::::::::::.:::: ::.:::.::::
CCDS31 KHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKKLMAFQPAPKVIRC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
::::::::.:::::::::::: ::::.:.:::.:::::::::::::::::::::::::::
CCDS31 MTNTPVVVQEGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH
:: :::::::::::::::::::..:::::::::::::: ::::: :::::: ::::::::
CCDS31 AFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL
::: :::::::::::::::::::::::::::::::..::::.:::.::.:::.::. ..:
CCDS31 ALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDRVKLESPTVSTL
250 260 270 280 290 300
310
pF1KE5 SPSGHTKLLPRSLAPAGKD
.::. ::: :::: .::
CCDS31 TPSSPGKLLTRSLALGGKKD
310 320
>>CCDS82221.1 PYCR1 gene_id:5831|Hs108|chr17 (217 aa)
initn: 1359 init1: 1359 opt: 1359 Z-score: 1686.0 bits: 319.6 E(32554): 1.4e-87
Smith-Waterman score: 1359; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214)
10 20 30 40 50 60
pF1KE5 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH
::::::::::::::::::::::::::::::::::
CCDS82 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAVHG
190 200 210
250 260 270 280 290 300
pF1KE5 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL
>>CCDS62365.1 PYCR1 gene_id:5831|Hs108|chr17 (288 aa)
initn: 1827 init1: 1149 opt: 1149 Z-score: 1424.4 bits: 271.6 E(32554): 5.1e-73
Smith-Waterman score: 1769; 90.3% identity (90.3% similar) in 319 aa overlap (1-319:1-288)
10 20 30 40 50 60
pF1KE5 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH
:::::::::::::::::::::::::::::
CCDS62 -------------------------------GAAKMLLHSEQHPGQLKDNVSSPGGATIH
190 200
250 260 270 280 290 300
pF1KE5 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL
210 220 230 240 250 260
310
pF1KE5 SPSGHTKLLPRSLAPAGKD
:::::::::::::::::::
CCDS62 SPSGHTKLLPRSLAPAGKD
270 280
>>CCDS6407.2 PYCRL gene_id:65263|Hs108|chr8 (286 aa)
initn: 758 init1: 519 opt: 768 Z-score: 953.2 bits: 184.4 E(32554): 8.9e-47
Smith-Waterman score: 768; 46.4% identity (74.5% similar) in 267 aa overlap (3-268:23-283)
10 20 30
pF1KE5 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSP-DMDL
:::.:::..: :.:.:. :: . :..:.::.: : .:
CCDS64 MGGERSGVRGNKMAAAEPSPRRVGFVGAGRMAGAIAQGLIRAGKVEAQHILASAPTDRNL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 ATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGV
.:: : . : :.:..: ....:.:::..: .: :.. . .::.:: ::::
CCDS64 CHFQAL---GCRTTHSNQEVLQSCLLVIFATKPHVLPAVLAEVAPVVTTEHILVSVAAGV
70 80 90 100 110
100 110 120 130 140 150
pF1KE5 TISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFC
..:..:. : : ::.: . : : ::.::: :.: : :. . .:...:: . : :
CCDS64 SLSTLEELLP---PNTRVLRVLPNLPCVVQEGAIVMARGRHVGSSETKLLQHLLEACGRC
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE5 TEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLH
:: : .: ::::::: :.. . .:::.:.::::.: :: :..::.:::.::::::
CCDS64 EEVPEAYVDIHTGLSGSGVAFVCAFSEALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLH
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE5 SEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSP
:::.::...: .:::.::..::.::.::.:. ..::::. :..::
CCDS64 EGQHPAQLRSDVCTPGGTTIYGLHALEQGGLRAATMSAVEAATCRAKELSRK
240 250 260 270 280
280 290 300 310
pF1KE5 AAIKKTILDKVKLDSPAGTALSPSGHTKLLPRSLAPAGKD
>>CCDS73039.1 PYCR2 gene_id:29920|Hs108|chr1 (246 aa)
initn: 745 init1: 723 opt: 742 Z-score: 922.1 bits: 178.5 E(32554): 4.8e-45
Smith-Waterman score: 1148; 64.2% identity (72.3% similar) in 318 aa overlap (1-318:1-244)
10 20 30 40 50 60
pF1KE5 MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETV
::::::::::::.:::.::::::.:.::::.::::.:.: ::::::::::.:: :::::
CCDS73 MSVGFIGAGQLAYALARGFTAAGILSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 QHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC
.::::::::::::::::::::::::.. :::::::::::::::.::
CCDS73 KHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEK--------------
70 80 90 100
130 140 150 160 170 180
pF1KE5 MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAY
CCDS73 ------------------------------------------------------------
190 200 210 220 230 240
pF1KE5 AFTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH
:: :::::::::::::::::::..:::::::::::::: ::::: :::::: ::::::::
CCDS73 AFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIH
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE5 ALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPAAIKKTILDKVKLDSPAGTAL
::: :::::::::::::::::::::::::::::::..::::.:::.::.:::.::. ..:
CCDS73 ALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDRVKLESPTVSTL
170 180 190 200 210 220
310
pF1KE5 SPSGHTKLLPRSLAPAGKD
.::. ::: :::: .::
CCDS73 TPSSPGKLLTRSLALGGKKD
230 240
319 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:45:52 2016 done: Mon Nov 7 23:45:52 2016
Total Scan time: 2.150 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]