FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6632, 247 aa
  1>>>pF1KE6632 247 - 247 aa - 247 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.1732+/-0.000378; mu= 20.6655+/- 0.023
 mean_var=58.5102+/-12.651, 0's: 0 Z-trim(111.6): 22  B-trim: 897 in 1/53
 Lambda= 0.167671
 statistics sampled from 20190 (20199) to 20190 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.237), width:  16
 Scan time:  6.410

The best scores are:                                      opt bits E(85289)
NP_004861 (OMIM: 604041,609180) mannose-P-dolichol ( 247) 1589 392.6 3.3e-109
XP_006721661 (OMIM: 604041,609180) PREDICTED: mann ( 259) 1083 270.2 2.4e-72
XP_011522383 (OMIM: 604041,609180) PREDICTED: mann ( 138)  884 221.8 4.8e-58
NP_001317002 (OMIM: 604041,609180) mannose-P-dolic ( 192)  850 213.8 1.8e-55
XP_006721660 (OMIM: 604041,609180) PREDICTED: mann ( 260)  838 211.0 1.7e-54


>>NP_004861 (OMIM: 604041,609180) mannose-P-dolichol uti  (247 aa)
 initn: 1589 init1: 1589 opt: 1589  Z-score: 2081.5  bits: 392.6 E(85289): 3.3e-109
Smith-Waterman score: 1589; 99.6% identity (100.0% similar) in 247 aa overlap (1-247:1-247)

               10        20        30        40        50        60
pF1KE6 MAAEADGPLKRLLVPILLPEKCYDQLFVQWDLLHVPCLKILLSKGLGLGIVAGSLLVKLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAAEADGPLKRLLVPILLPEKCYDQLFVQWDLLHVPCLKILLSKGLGLGIVAGSLLVKLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 QVFKILGAKSAEGLSLQSVMLELVALTGTMVYSITNNFPFSSWGEALFLMLQTITICFLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QVFKILGAKSAEGLSLQSVMLELVALTGTMVYSITNNFPFSSWGEALFLMLQTITICFLV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 MHYRGQTVKGVAFLACYGLVLLVLLSPLTPLTVVTLLQASNVPAVVVGRLLQAATNYHNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MHYRGQTVKGVAFLACYGLVLLVLLSPLTPLTVVTLLQASNVPAVVVGRLLQAATNYHNG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 HTGQLSAITVFLLFGGSLARIFTSIQETGDPLMAGTFVVSSLCNGLIATQLLFYWNAKPP
       ::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
NP_004 HTGQLSAITVFLLFGGSLARIFTSIQETGDPLMAGTFVVSSLCNGLIAAQLLFYWNAKPP
              190       200       210       220       230       240

              
pF1KE6 HKQKKAQ
       :::::::
NP_004 HKQKKAQ
              

>>XP_006721661 (OMIM: 604041,609180) PREDICTED: mannose-  (259 aa)
 initn: 1083 init1: 1083 opt: 1083  Z-score: 1419.7  bits: 270.2 E(85289): 2.4e-72
Smith-Waterman score: 1083; 99.4% identity (100.0% similar) in 170 aa overlap (1-170:1-170)

               10        20        30        40        50        60
pF1KE6 MAAEADGPLKRLLVPILLPEKCYDQLFVQWDLLHVPCLKILLSKGLGLGIVAGSLLVKLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAEADGPLKRLLVPILLPEKCYDQLFVQWDLLHVPCLKILLSKGLGLGIVAGSLLVKLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 QVFKILGAKSAEGLSLQSVMLELVALTGTMVYSITNNFPFSSWGEALFLMLQTITICFLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVFKILGAKSAEGLSLQSVMLELVALTGTMVYSITNNFPFSSWGEALFLMLQTITICFLV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 MHYRGQTVKGVAFLACYGLVLLVLLSPLTPLTVVTLLQASNVPAVVVGRLLQAATNYHNG
       :::::::::::::::::::::::::::::::::::::::::::::::::.          
XP_006 MHYRGQTVKGVAFLACYGLVLLVLLSPLTPLTVVTLLQASNVPAVVVGRVGTRSKGQDVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 HTGQLSAITVFLLFGGSLARIFTSIQETGDPLMAGTFVVSSLCNGLIATQLLFYWNAKPP
                                                                   
XP_006 GAGWGGRVEDQSVGVLYLGEHGKSSGDRAKGLNSSPSFSRQPPTTTTGTQASSQPSQSSC
              190       200       210       220       230       240

>>XP_011522383 (OMIM: 604041,609180) PREDICTED: mannose-  (138 aa)
 initn: 884 init1: 884 opt: 884  Z-score: 1163.0  bits: 221.8 E(85289): 4.8e-58
Smith-Waterman score: 884; 99.3% identity (100.0% similar) in 138 aa overlap (110-247:1-138)

      80        90       100       110       120       130         
pF1KE6 MLELVALTGTMVYSITNNFPFSSWGEALFLMLQTITICFLVMHYRGQTVKGVAFLACYGL
                                     ::::::::::::::::::::::::::::::
XP_011                               MLQTITICFLVMHYRGQTVKGVAFLACYGL
                                             10        20        30

     140       150       160       170       180       190         
pF1KE6 VLLVLLSPLTPLTVVTLLQASNVPAVVVGRLLQAATNYHNGHTGQLSAITVFLLFGGSLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLVLLSPLTPLTVVTLLQASNVPAVVVGRLLQAATNYHNGHTGQLSAITVFLLFGGSLA
               40        50        60        70        80        90

     200       210       220       230       240       
pF1KE6 RIFTSIQETGDPLMAGTFVVSSLCNGLIATQLLFYWNAKPPHKQKKAQ
       :::::::::::::::::::::::::::::.::::::::::::::::::
XP_011 RIFTSIQETGDPLMAGTFVVSSLCNGLIAAQLLFYWNAKPPHKQKKAQ
              100       110       120       130        

>>NP_001317002 (OMIM: 604041,609180) mannose-P-dolichol   (192 aa)
 initn: 846 init1: 846 opt: 850  Z-score: 1116.8  bits: 213.8 E(85289): 1.8e-55
Smith-Waterman score: 850; 83.4% identity (87.6% similar) in 169 aa overlap (1-164:1-169)

               10        20        30        40        50        60
pF1KE6 MAAEADGPLKRLLVPILLPEKCYDQLFVQWDLLHVPCLKILLSKGLGLGIVAGSLLVKLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAEADGPLKRLLVPILLPEKCYDQLFVQWDLLHVPCLKILLSKGLGLGIVAGSLLVKLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 QVFKILGAKSAEGLSLQSVMLELVALTGTMVYSITNNFPFSSWGEALFLMLQTITICFLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVFKILGAKSAEGLSLQSVMLELVALTGTMVYSITNNFPFSSWGEALFLMLQTITICFLV
               70        80        90       100       110       120

              130           140        150       160       170     
pF1KE6 MHYRGQTVKGVAFLA----CYGLVLLVLLS-PLTPLTVVTLLQASNVPAVVVGRLLQAAT
       ::::::::::.. :     : .      ::    : :..:  :::. :.           
NP_001 MHYRGQTVKGAGDLPKSRLCGSWEPCWELSFSRQPPTTTTGTQASSQPSQSSCCLGAPWP
              130       140       150       160       170       180

         180       190       200       210       220       230     
pF1KE6 NYHNGHTGQLSAITVFLLFGGSLARIFTSIQETGDPLMAGTFVVSSLCNGLIATQLLFYW
                                                                   
NP_001 ESSLPFRKPEIP                                                
              190                                                  

>>XP_006721660 (OMIM: 604041,609180) PREDICTED: mannose-  (260 aa)
 initn: 838 init1: 838 opt: 838  Z-score: 1099.4  bits: 211.0 E(85289): 1.7e-54
Smith-Waterman score: 838; 100.0% identity (100.0% similar) in 129 aa overlap (1-129:1-129)

               10        20        30        40        50        60
pF1KE6 MAAEADGPLKRLLVPILLPEKCYDQLFVQWDLLHVPCLKILLSKGLGLGIVAGSLLVKLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAAEADGPLKRLLVPILLPEKCYDQLFVQWDLLHVPCLKILLSKGLGLGIVAGSLLVKLP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 QVFKILGAKSAEGLSLQSVMLELVALTGTMVYSITNNFPFSSWGEALFLMLQTITICFLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QVFKILGAKSAEGLSLQSVMLELVALTGTMVYSITNNFPFSSWGEALFLMLQTITICFLV
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 MHYRGQTVKGVAFLACYGLVLLVLLSPLTPLTVVTLLQASNVPAVVVGRLLQAATNYHNG
       :::::::::                                                   
XP_006 MHYRGQTVKASPGSHQLPQRAHRPALSHHSLPAVWGLPGPNLHFHSGNRRSPDGWDLCGL
              130       140       150       160       170       180




247 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 14:57:14 2016 done: Tue Nov  8 14:57:15 2016
 Total Scan time:  6.410 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]