Result of FASTA (omim) for
pFN21AE6748
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6748, 547 aa
1>>>pF1KE6748 547 - 547 aa - 547 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8000+/-0.000408; mu= 15.0167+/- 0.025
mean_var=60.6548+/-11.966, 0's: 0 Z-trim(109.3): 33 B-trim: 35 in 1/55
Lambda= 0.164680
statistics sampled from 17469 (17500) to 17469 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.559), E-opt: 0.2 (0.205), width: 16
Scan time: 6.710
The best scores are: opt bits E(85289)
NP_059125 (OMIM: 115300,605748) beta,beta-carotene ( 547) 3679 883.1 0
XP_016878776 (OMIM: 115300,605748) PREDICTED: beta ( 435) 2909 700.2 3.4e-201
XP_016878775 (OMIM: 115300,605748) PREDICTED: beta ( 478) 2694 649.1 8.9e-186
XP_016878777 (OMIM: 115300,605748) PREDICTED: beta ( 406) 2683 646.5 4.7e-185
XP_011521411 (OMIM: 115300,605748) PREDICTED: beta ( 480) 2471 596.1 8e-170
XP_016878778 (OMIM: 115300,605748) PREDICTED: beta ( 288) 1933 468.3 1.5e-131
NP_001032367 (OMIM: 611740) beta,beta-carotene 9', ( 545) 1420 346.4 1.3e-94
NP_114144 (OMIM: 611740) beta,beta-carotene 9',10' ( 579) 1420 346.4 1.4e-94
NP_001243326 (OMIM: 611740) beta,beta-carotene 9', ( 539) 1399 341.4 4.2e-93
NP_000320 (OMIM: 180069,204100,613794) retinoid is ( 533) 1374 335.5 2.5e-91
XP_016857516 (OMIM: 180069,204100,613794) PREDICTE ( 441) 1129 277.3 7e-74
NP_001243329 (OMIM: 611740) beta,beta-carotene 9', ( 474) 926 229.0 2.5e-59
NP_001243327 (OMIM: 611740) beta,beta-carotene 9', ( 506) 416 107.9 7.9e-23
>>NP_059125 (OMIM: 115300,605748) beta,beta-carotene 15, (547 aa)
initn: 3679 init1: 3679 opt: 3679 Z-score: 4720.0 bits: 883.1 E(85289): 0
Smith-Waterman score: 3679; 99.8% identity (99.8% similar) in 547 aa overlap (1-547:1-547)
10 20 30 40 50 60
pF1KE6 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHWFDGLALLHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHWFDGLALLHSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 TIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLATSHPHYDEAGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 TDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLATSHPHYDEAGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSLLSPSYYHSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 VLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSLLSPSYYHSFG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 VTENYVIFLEQPFRLDILKMATAYIRSMSWASCLAFHREEKTYIHIIDQRTRQPVQTKFY
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
NP_059 VTENYVIFLEQPFRLDILKMATAYIRRMSWASCLAFHREEKTYIHIIDQRTRQPVQTKFY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSRLTSVPTLRRFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 TDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSRLTSVPTLRRFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEGLELPRVNYAHNGKQYRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 VPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEGLELPRVNYAHNGKQYRY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 VFATGVQWSPIPTKIIKYDILTKSSLKWREDDCWPAEPLFVPAPGAKDEDDGVILSAIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 VFATGVQWSPIPTKIIKYDILTKSSLKWREDDCWPAEPLFVPAPGAKDEDDGVILSAIVS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 TDPQKLPFLLILDAKSFTELARASVDVDMHMDLHGLFITDMDWDTKKQAASEEQRDRASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 TDPQKLPFLLILDAKSFTELARASVDVDMHMDLHGLFITDMDWDTKKQAASEEQRDRASD
490 500 510 520 530 540
pF1KE6 CHGAPLT
:::::::
NP_059 CHGAPLT
>>XP_016878776 (OMIM: 115300,605748) PREDICTED: beta,bet (435 aa)
initn: 2909 init1: 2909 opt: 2909 Z-score: 3733.0 bits: 700.2 E(85289): 3.4e-201
Smith-Waterman score: 2909; 99.8% identity (99.8% similar) in 434 aa overlap (1-434:1-434)
10 20 30 40 50 60
pF1KE6 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHWFDGLALLHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHWFDGLALLHSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLATSHPHYDEAGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLATSHPHYDEAGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSLLSPSYYHSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSLLSPSYYHSFG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 VTENYVIFLEQPFRLDILKMATAYIRSMSWASCLAFHREEKTYIHIIDQRTRQPVQTKFY
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_016 VTENYVIFLEQPFRLDILKMATAYIRRMSWASCLAFHREEKTYIHIIDQRTRQPVQTKFY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSRLTSVPTLRRFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSRLTSVPTLRRFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEGLELPRVNYAHNGKQYRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEGLELPRVNYAHNGKQYRY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 VFATGVQWSPIPTKIIKYDILTKSSLKWREDDCWPAEPLFVPAPGAKDEDDGVILSAIVS
::::::::::::::
XP_016 VFATGVQWSPIPTKE
430
>>XP_016878775 (OMIM: 115300,605748) PREDICTED: beta,bet (478 aa)
initn: 2718 init1: 2694 opt: 2694 Z-score: 3456.2 bits: 649.1 E(85289): 8.9e-186
Smith-Waterman score: 3036; 87.2% identity (87.2% similar) in 547 aa overlap (1-547:1-478)
10 20 30 40 50 60
pF1KE6 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHWFDGLALLHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHWFDGLALLHSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLATSHPHYDEAGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLATSHPHYDEAGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSLLSPSYYHSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSLLSPSYYHSFG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 VTENYVIFLEQPFRLDILKMATAYIRSMSWASCLAFHREEKTYIHIIDQRTRQPVQTKFY
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_016 VTENYVIFLEQPFRLDILKMATAYIRRMSWASCLAFHREEKTYIHIIDQRTRQPVQTKFY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSRLTSVPTLRRFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSRLTSVPTLRRFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEGLELPRVNYAHNGKQYRY
:::::::::::::::::::::::::::::::::::::::::::
XP_016 VPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEG-----------------
370 380 390 400
430 440 450 460 470 480
pF1KE6 VFATGVQWSPIPTKIIKYDILTKSSLKWREDDCWPAEPLFVPAPGAKDEDDGVILSAIVS
::::::::
XP_016 ----------------------------------------------------VILSAIVS
410
490 500 510 520 530 540
pF1KE6 TDPQKLPFLLILDAKSFTELARASVDVDMHMDLHGLFITDMDWDTKKQAASEEQRDRASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDPQKLPFLLILDAKSFTELARASVDVDMHMDLHGLFITDMDWDTKKQAASEEQRDRASD
420 430 440 450 460 470
pF1KE6 CHGAPLT
:::::::
XP_016 CHGAPLT
>>XP_016878777 (OMIM: 115300,605748) PREDICTED: beta,bet (406 aa)
initn: 2683 init1: 2683 opt: 2683 Z-score: 3443.3 bits: 646.5 E(85289): 4.7e-185
Smith-Waterman score: 2683; 99.8% identity (99.8% similar) in 402 aa overlap (1-402:1-402)
10 20 30 40 50 60
pF1KE6 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHWFDGLALLHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHWFDGLALLHSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLATSHPHYDEAGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLATSHPHYDEAGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSLLSPSYYHSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSLLSPSYYHSFG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 VTENYVIFLEQPFRLDILKMATAYIRSMSWASCLAFHREEKTYIHIIDQRTRQPVQTKFY
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_016 VTENYVIFLEQPFRLDILKMATAYIRRMSWASCLAFHREEKTYIHIIDQRTRQPVQTKFY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSRLTSVPTLRRFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSRLTSVPTLRRFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEGLELPRVNYAHNGKQYRY
::::::::::::::::::::::::::::::::::::::::::
XP_016 VPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEDNKI
370 380 390 400
430 440 450 460 470 480
pF1KE6 VFATGVQWSPIPTKIIKYDILTKSSLKWREDDCWPAEPLFVPAPGAKDEDDGVILSAIVS
>>XP_011521411 (OMIM: 115300,605748) PREDICTED: beta,bet (480 aa)
initn: 2462 init1: 2462 opt: 2471 Z-score: 3169.9 bits: 596.1 E(85289): 8e-170
Smith-Waterman score: 3088; 87.6% identity (87.6% similar) in 547 aa overlap (1-547:1-480)
10 20 30 40 50 60
pF1KE6 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHWFDGLALLHSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHWFDGLALLHSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAFSYLSHTIPDF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLATSHPHYDEAGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLATSHPHYDEAGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSLLSPSYYHSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSLLSPSYYHSFG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 VTENYVIFLEQPFRLDILKMATAYIRSMSWASCLAFHREEKTYIHIIDQRTRQPVQTKFY
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
XP_011 VTENYVIFLEQPFRLDILKMATAYIRRMSWASCLAFHREEKTYIHIIDQRTRQPVQTKFY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSRLTSVPTLRRFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSRLTSVPTLRRFA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEGLELPRVNYAHNGKQYRY
:::::::
XP_011 VPLHVDK-----------------------------------------------------
430 440 450 460 470 480
pF1KE6 VFATGVQWSPIPTKIIKYDILTKSSLKWREDDCWPAEPLFVPAPGAKDEDDGVILSAIVS
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 --------------IIKYDILTKSSLKWREDDCWPAEPLFVPAPGAKDEDDGVILSAIVS
370 380 390 400 410
490 500 510 520 530 540
pF1KE6 TDPQKLPFLLILDAKSFTELARASVDVDMHMDLHGLFITDMDWDTKKQAASEEQRDRASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDPQKLPFLLILDAKSFTELARASVDVDMHMDLHGLFITDMDWDTKKQAASEEQRDRASD
420 430 440 450 460 470
pF1KE6 CHGAPLT
:::::::
XP_011 CHGAPLT
480
>>XP_016878778 (OMIM: 115300,605748) PREDICTED: beta,bet (288 aa)
initn: 1933 init1: 1933 opt: 1933 Z-score: 2482.9 bits: 468.3 E(85289): 1.5e-131
Smith-Waterman score: 1933; 99.7% identity (99.7% similar) in 288 aa overlap (260-547:1-288)
230 240 250 260 270 280
pF1KE6 LLSPSYYHSFGVTENYVIFLEQPFRLDILKMATAYIRSMSWASCLAFHREEKTYIHIIDQ
::::::: ::::::::::::::::::::::
XP_016 MATAYIRRMSWASCLAFHREEKTYIHIIDQ
10 20 30
290 300 310 320 330 340
pF1KE6 RTRQPVQTKFYTDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTRQPVQTKFYTDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQDFKENSR
40 50 60 70 80 90
350 360 370 380 390 400
pF1KE6 LTSVPTLRRFAVPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEGLELPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSVPTLRRFAVPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEGLELPRV
100 110 120 130 140 150
410 420 430 440 450 460
pF1KE6 NYAHNGKQYRYVFATGVQWSPIPTKIIKYDILTKSSLKWREDDCWPAEPLFVPAPGAKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NYAHNGKQYRYVFATGVQWSPIPTKIIKYDILTKSSLKWREDDCWPAEPLFVPAPGAKDE
160 170 180 190 200 210
470 480 490 500 510 520
pF1KE6 DDGVILSAIVSTDPQKLPFLLILDAKSFTELARASVDVDMHMDLHGLFITDMDWDTKKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDGVILSAIVSTDPQKLPFLLILDAKSFTELARASVDVDMHMDLHGLFITDMDWDTKKQA
220 230 240 250 260 270
530 540
pF1KE6 ASEEQRDRASDCHGAPLT
::::::::::::::::::
XP_016 ASEEQRDRASDCHGAPLT
280
>>NP_001032367 (OMIM: 611740) beta,beta-carotene 9',10'- (545 aa)
initn: 1268 init1: 416 opt: 1420 Z-score: 1819.4 bits: 346.4 E(85289): 1.3e-94
Smith-Waterman score: 1420; 41.7% identity (71.6% similar) in 518 aa overlap (16-518:34-543)
10 20 30 40
pF1KE6 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGES
. :.: :..: ::.:.::: ::: :..
NP_001 TPQKKAVFGQCRGLPCVAPLLTTVEEAPRGISARVWGHFPKWLNGSLLRIGPGKFEFGKD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 RYNHWFDGLALLHSFTIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNI
.:::::::.::::.: . : : ::::.:.::::..: ::::.:::::.: ::::::.
NP_001 KYNHWFDGMALLHQFRMAKGTVTYRSKFLQSDTYKANSAKNRIVISEFGTLALPDPCKNV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 FSKAFSY--LSHTIPDFTDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKY
: . .: : .::: .: .. :.: .:::.. :.. .::: ::::. :.
NP_001 FERFMSRFELPGKAAAMTDNTNVNYVRYKGDYYLCTETNFMNKVDIETLEKTEKVDWSKF
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE6 VAVNLATSHPHYDEAGNVLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFC
.::: ::.::::: :.. :::.:. : . : ....: :: :.. . ..:.:
NP_001 IAVNGATAHPHYDPDGTAYNMGNSFGPYGFS-YKVIRVP---PEKVDLGETI-HGVQVIC
190 200 210 220 230
230 240 250 260 270 280
pF1KE6 SIPSRSLLSPSYYHSFGVTENYVIFLEQPFRLDILKMATAYIRSMSWASCLAFHREEKTY
:: : .::::::::.:.::.::.:::..... :.::. ::. .... .... . .:
NP_001 SIASTEKGKPSYYHSFGMTRNYIIFIEQPLKMNLWKIATSKIRGKAFSDGISWEPQCNTR
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE6 IHIIDQRTRQPVQTKFYTDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQ-
.:....:: : . ..:. .:.::..::.:..::...:. ... ... : :: .
NP_001 FHVVEKRTGQLLPGRYYSKPFVTFHQINAFEDQGCVIIDLCCQDNGRTLEVYQLQNLRKA
300 310 320 330 340 350
350 360 370 380 390
pF1KE6 ----DFKENSRLTSVPTLRRFAVPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPE
: .:: : : :::..::.:. :: : :: .. :.:.:.:. :: ..:. :
NP_001 GEGLDQVHNSAAKSFP--RRFVLPLNVSLNAPEGDNLSPLSYTSASAVKQADGTIWCSHE
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE6 FLYE-------GLELPRVNYAH-NGKQYRYVFATGVQWSPIPTKIIKYDILTKSSLKWRE
:.. :.:.:.. : . .::.:.. .. : . . ..:: :...:. :::
NP_001 NLHQEDLEKEGGIEFPQIYYDRFSGKKYHFFYGCGFR-HLVGDSLIKVDVVNKTLKVWRE
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE6 DDCWPAEPLFVPAPGAKDEDDGVILSAIVSTDPQKLPFLLILDAKSFTELARASVDVDMH
: .:.::.::::::...:: :::::.... . .. :::.::::.: ::.:: : :.:
NP_001 DGFYPSEPVFVPAPGTNEEDGGVILSVVITPNQNESNFLLVLDAKNFEELGRAEVPVQMP
480 490 500 510 520 530
520 530 540
pF1KE6 MDLHGLFITDMDWDTKKQAASEEQRDRASDCHGAPLT
. .:: ::
NP_001 YGFHGTFIPI
540
>>NP_114144 (OMIM: 611740) beta,beta-carotene 9',10'-oxy (579 aa)
initn: 1268 init1: 416 opt: 1420 Z-score: 1819.0 bits: 346.4 E(85289): 1.4e-94
Smith-Waterman score: 1420; 41.7% identity (71.6% similar) in 518 aa overlap (16-518:68-577)
10 20 30 40
pF1KE6 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGES
. :.: :..: ::.:.::: ::: :..
NP_114 TPQKKAVFGQCRGLPCVAPLLTTVEEAPRGISARVWGHFPKWLNGSLLRIGPGKFEFGKD
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE6 RYNHWFDGLALLHSFTIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNI
.:::::::.::::.: . : : ::::.:.::::..: ::::.:::::.: ::::::.
NP_114 KYNHWFDGMALLHQFRMAKGTVTYRSKFLQSDTYKANSAKNRIVISEFGTLALPDPCKNV
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE6 FSKAFSY--LSHTIPDFTDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKY
: . .: : .::: .: .. :.: .:::.. :.. .::: ::::. :.
NP_114 FERFMSRFELPGKAAAMTDNTNVNYVRYKGDYYLCTETNFMNKVDIETLEKTEKVDWSKF
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE6 VAVNLATSHPHYDEAGNVLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFC
.::: ::.::::: :.. :::.:. : . : ....: :: :.. . ..:.:
NP_114 IAVNGATAHPHYDPDGTAYNMGNSFGPYGFS-YKVIRVP---PEKVDLGETI-HGVQVIC
220 230 240 250 260 270
230 240 250 260 270 280
pF1KE6 SIPSRSLLSPSYYHSFGVTENYVIFLEQPFRLDILKMATAYIRSMSWASCLAFHREEKTY
:: : .::::::::.:.::.::.:::..... :.::. ::. .... .... . .:
NP_114 SIASTEKGKPSYYHSFGMTRNYIIFIEQPLKMNLWKIATSKIRGKAFSDGISWEPQCNTR
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE6 IHIIDQRTRQPVQTKFYTDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQ-
.:....:: : . ..:. .:.::..::.:..::...:. ... ... : :: .
NP_114 FHVVEKRTGQLLPGRYYSKPFVTFHQINAFEDQGCVIIDLCCQDNGRTLEVYQLQNLRKA
340 350 360 370 380 390
350 360 370 380 390
pF1KE6 ----DFKENSRLTSVPTLRRFAVPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPE
: .:: : : :::..::.:. :: : :: .. :.:.:.:. :: ..:. :
NP_114 GEGLDQVHNSAAKSFP--RRFVLPLNVSLNAPEGDNLSPLSYTSASAVKQADGTIWCSHE
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE6 FLYE-------GLELPRVNYAH-NGKQYRYVFATGVQWSPIPTKIIKYDILTKSSLKWRE
:.. :.:.:.. : . .::.:.. .. : . . ..:: :...:. :::
NP_114 NLHQEDLEKEGGIEFPQIYYDRFSGKKYHFFYGCGFR-HLVGDSLIKVDVVNKTLKVWRE
460 470 480 490 500
460 470 480 490 500 510
pF1KE6 DDCWPAEPLFVPAPGAKDEDDGVILSAIVSTDPQKLPFLLILDAKSFTELARASVDVDMH
: .:.::.::::::...:: :::::.... . .. :::.::::.: ::.:: : :.:
NP_114 DGFYPSEPVFVPAPGTNEEDGGVILSVVITPNQNESNFLLVLDAKNFEELGRAEVPVQMP
510 520 530 540 550 560
520 530 540
pF1KE6 MDLHGLFITDMDWDTKKQAASEEQRDRASDCHGAPLT
. .:: ::
NP_114 YGFHGTFIPI
570
>>NP_001243326 (OMIM: 611740) beta,beta-carotene 9',10'- (539 aa)
initn: 1254 init1: 416 opt: 1399 Z-score: 1792.6 bits: 341.4 E(85289): 4.2e-93
Smith-Waterman score: 1399; 41.5% identity (71.0% similar) in 518 aa overlap (16-518:34-537)
10 20 30 40
pF1KE6 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGES
. :.: :..: ::.:.::: ::: :..
NP_001 TPQKKAVFGQCRGLPCVAPLLTTVEEAPRGISARVWGHFPKWLNGSLLRIGPGKFEFGKD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 RYNHWFDGLALLHSFTIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNI
.:::::::.::::.: . : : ::::.:.::::..: ::::.:::::.: ::::::.
NP_001 KYNHWFDGMALLHQFRMAKGTVTYRSKFLQSDTYKANSAKNRIVISEFGTLALPDPCKNV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 FSKAFSY--LSHTIPDFTDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKY
: . .: : .::: .: .. :.: .:::.. :.. .::: ::::. :.
NP_001 FERFMSRFELPGKAAAMTDNTNVNYVRYKGDYYLCTETNFMNKVDIETLEKTEKVDWSKF
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE6 VAVNLATSHPHYDEAGNVLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFC
.::: ::.::::: :.. :::.:. : . : ....: :: :.. . ..:.:
NP_001 IAVNGATAHPHYDPDGTAYNMGNSFGPYGFS-YKVIRVP---PEKVDLGETI-HGVQVIC
190 200 210 220 230
230 240 250 260 270 280
pF1KE6 SIPSRSLLSPSYYHSFGVTENYVIFLEQPFRLDILKMATAYIRSMSWASCLAFHREEKTY
:: : .::::::::.:.::.::.:::..... :.::. ::. .... .... . .:
NP_001 SIASTEKGKPSYYHSFGMTRNYIIFIEQPLKMNLWKIATSKIRGKAFSDGISWEPQCNTR
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE6 IHIIDQRTRQPVQTKFYTDAMVVFHHVNAYEEDGCIVFDVIAYEDNSLYQLFYLANLNQ-
.:....:: : . ..:. .:.::..::.:..::...:. ... ... : :: .
NP_001 FHVVEKRTGQLLPGRYYSKPFVTFHQINAFEDQGCVIIDLCCQDNGRTLEVYQLQNLRKA
300 310 320 330 340 350
350 360 370 380 390
pF1KE6 ----DFKENSRLTSVPTLRRFAVPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPE
: .:: : : :::..::.:. :: : :: .. :.:.:.:. :: ..:. :
NP_001 GEGLDQVHNSAAKSFP--RRFVLPLNVSLNAPEGDNLSPLSYTSASAVKQADGTIWCSHE
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE6 FLYE-------GLELPRVNYAH-NGKQYRYVFATGVQWSPIPTKIIKYDILTKSSLKWRE
:.. :.:.:.. : . .::.:.. .. : . . ..:: :.. :::
NP_001 NLHQEDLEKEGGIEFPQIYYDRFSGKKYHFFYGCGFR-HLVGDSLIKVDVV------WRE
420 430 440 450 460
460 470 480 490 500 510
pF1KE6 DDCWPAEPLFVPAPGAKDEDDGVILSAIVSTDPQKLPFLLILDAKSFTELARASVDVDMH
: .:.::.::::::...:: :::::.... . .. :::.::::.: ::.:: : :.:
NP_001 DGFYPSEPVFVPAPGTNEEDGGVILSVVITPNQNESNFLLVLDAKNFEELGRAEVPVQMP
470 480 490 500 510 520
520 530 540
pF1KE6 MDLHGLFITDMDWDTKKQAASEEQRDRASDCHGAPLT
. .:: ::
NP_001 YGFHGTFIPI
530
>>NP_000320 (OMIM: 180069,204100,613794) retinoid isomer (533 aa)
initn: 1222 init1: 395 opt: 1374 Z-score: 1760.5 bits: 335.5 E(85289): 2.5e-91
Smith-Waterman score: 1374; 39.7% identity (72.1% similar) in 519 aa overlap (10-517:20-530)
10 20 30 40 50
pF1KE6 MDIIFGRNRKEQLEPVRAKVTGKIPAWLQGTLLRNGPGMHTVGESRYNHW
.: :. :.:::.:: :: :.::: :::. :: . :
NP_000 MSIQVEHPAGGYKKLFETVEELSSPLTAHVTGRIPLWLTGSLLRCGPGLFEVGSEPFYHL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 FDGLALLHSFTIRDGEVYYRSKYLRSDTYNTNIEANRIVVSEFGTMAYPDPCKNIFSKAF
::: ::::.: ...:.: :. ...:.:.: . .:::..:::: :.:::::::::. :
NP_000 FDGQALLHKFDFKEGHVTYHRRFIRTDAYVRAMTEKRIVITEFGTCAFPDPCKNIFSRFF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 SYLSHTIPDFTDNCLINIMKCGEDFYATSETNYIRKINPQTLETLEKVDYRKYVAVNLAT
::. . . ::: :.:.. :::.:: .:::.: ::::.::::...:: .::.:: ::
NP_000 SYFRGV--EVTDNALVNVYPVGEDYYACTETNFITKINPETLETIKQVDLCNYVSVNGAT
130 140 150 160 170
180 190 200 210 220 230
pF1KE6 SHPHYDEAGNVLNMGTSIVEKGKTKYVIFKIPATVPEGKKQGKSPWKHTEVFCSIPSRSL
.::: .. :.: :.:. . .. . : : ::: . . ..: ...:. ..: .
NP_000 AHPHIENDGTVYNIGNCFGKNFSIAYNIVKIPPL----QADKEDPISKSEIVVQFPCSDR
180 190 200 210 220 230
240 250 260 270 280
pF1KE6 LSPSYYHSFGVTENYVIFLEQPFRLDILKMATAY-IRSMSWASCLAFHREEKTYIHIIDQ
..::: ::::.: ::..:.: : .....:. ... . . .. .:. .. ...:: :.
NP_000 FKPSYVHSFGLTPNYIVFVETPVKINLFKFLSSWSLWGANYMDCFESNETMGVWLHIADK
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE6 RTRQPVQTKFYTDAMVVFHHVNAYEEDGCIVFDVIAYED-NSLYQLFYLANLNQDFKE--
. .. ...:. :. . .:::.:.::..: .. :. .. . .:. .::::: ....:
NP_000 KRKKYLNNKYRTSPFNLFHHINTYEDNGFLIVDLCCWKGFEFVYNYLYLANLRENWEEVK
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE6 -NSRLTSVPTLRRFAVPLHVDKNAEVGTNLIKVASTTATALKEEDGQVYCQPEFLYEG--
:.: . : .::...::..:: :..: ::. . .:::::. : .. .:: :. :
NP_000 KNARKAPQPEVRRYVLPLNIDK-ADTGKNLVTLPNTTATAILCSDETIWLEPEVLFSGPR
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE6 --LELPRVNYA-HNGKQYRYVFATGVQWSPIPTKIIKYDILTKSSLKWREDDCWPAEPLF
.:.:..:: . :: : :... :.. .: .. : .. :: . :.: : .:.::.:
NP_000 QAFEFPQINYQKYCGKPYTYAYGLGLN-HFVPDRLCKLNVKTKETWVWQEPDSYPSEPIF
420 430 440 450 460 470
470 480 490 500 510
pF1KE6 VPAPGAKDEDDGVILSAIVSTDP-QKLPFLLILDAKSFTELARASVDVDMHMDLHGLFIT
: : : .:::::.::..:: :: .::::.::...:.::: :.... . .::::
NP_000 VSHPDALEEDDGVVLSVVVSPGAGQKPAYLLILNAKDLSEVARAEVEINIPVTFHGLFKK
480 490 500 510 520 530
520 530 540
pF1KE6 DMDWDTKKQAASEEQRDRASDCHGAPLT
NP_000 S
547 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:59:35 2016 done: Tue Nov 8 15:59:36 2016
Total Scan time: 6.710 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]