Result of FASTA (omim) for
pFN21AE6184
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6184, 142 aa
1>>>pF1KE6184 142 - 142 aa - 142 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5313+/-0.000318; mu= 9.5736+/- 0.020
mean_var=57.3187+/-11.517, 0's: 0 Z-trim(116.1): 26 B-trim: 244 in 1/50
Lambda= 0.169405
statistics sampled from 27055 (27081) to 27055 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.318), width: 16
Scan time: 3.870
The best scores are: opt bits E(85289)
NP_005322 (OMIM: 142240) hemoglobin subunit theta- ( 142) 918 232.1 2.3e-61
NP_000508 (OMIM: 140700,141850,604131,613978) hemo ( 142) 588 151.5 4.4e-37
NP_000549 (OMIM: 140700,141800,604131,613978) hemo ( 142) 588 151.5 4.4e-37
NP_005323 (OMIM: 142310) hemoglobin subunit zeta [ ( 142) 485 126.3 1.7e-29
XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin ( 142) 485 126.3 1.7e-29
XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin ( 154) 485 126.3 1.8e-29
NP_001003938 (OMIM: 609639) hemoglobin subunit mu ( 141) 364 96.7 1.3e-20
NP_000175 (OMIM: 141749,142250,613977) hemoglobin ( 147) 322 86.4 1.7e-17
NP_000510 (OMIM: 142000) hemoglobin subunit delta ( 147) 321 86.2 2e-17
NP_000550 (OMIM: 141749,142200) hemoglobin subunit ( 147) 318 85.5 3.3e-17
NP_005321 (OMIM: 142100) hemoglobin subunit epsilo ( 147) 318 85.5 3.3e-17
NP_000509 (OMIM: 140700,141749,141900,603902,60390 ( 147) 316 85.0 4.7e-17
NP_976312 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 176 50.8 9.7e-07
NP_976311 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 176 50.8 9.7e-07
NP_005359 (OMIM: 160000) myoglobin [Homo sapiens] ( 154) 176 50.8 9.7e-07
XP_005261662 (OMIM: 160000) PREDICTED: myoglobin i ( 154) 176 50.8 9.7e-07
XP_016879605 (OMIM: 608759) PREDICTED: cytoglobin ( 137) 150 44.4 7.1e-05
NP_599030 (OMIM: 608759) cytoglobin [Homo sapiens] ( 190) 145 43.2 0.00023
XP_005257062 (OMIM: 608759) PREDICTED: cytoglobin ( 202) 145 43.2 0.00024
>>NP_005322 (OMIM: 142240) hemoglobin subunit theta-1 [H (142 aa)
initn: 918 init1: 918 opt: 918 Z-score: 1222.6 bits: 232.1 E(85289): 2.3e-61
Smith-Waterman score: 918; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE6 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHLDLSPGSSQVRAHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHLDLSPGSSQVRAHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 QKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARHYPGDFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARHYPGDFSP
70 80 90 100 110 120
130 140
pF1KE6 ALQASLDKFLSHVISALVSEYR
::::::::::::::::::::::
NP_005 ALQASLDKFLSHVISALVSEYR
130 140
>>NP_000508 (OMIM: 140700,141850,604131,613978) hemoglob (142 aa)
initn: 588 init1: 588 opt: 588 Z-score: 786.7 bits: 151.5 E(85289): 4.4e-37
Smith-Waterman score: 588; 62.0% identity (87.3% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE6 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHLDLSPGSSQVRAHG
:.:: :.. :.: : :.:...: : .::::: ::.::.::::: :.::: ::.::..::
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 QKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARHYPGDFSP
.::::::. :: ..::.:.:::::: ::: .:::::..:.::.:::::::: : :..:.:
NP_000 KKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTP
70 80 90 100 110 120
130 140
pF1KE6 ALQASLDKFLSHVISALVSEYR
:..:::::::. : ..:.:.::
NP_000 AVHASLDKFLASVSTVLTSKYR
130 140
>>NP_000549 (OMIM: 140700,141800,604131,613978) hemoglob (142 aa)
initn: 588 init1: 588 opt: 588 Z-score: 786.7 bits: 151.5 E(85289): 4.4e-37
Smith-Waterman score: 588; 62.0% identity (87.3% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE6 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHLDLSPGSSQVRAHG
:.:: :.. :.: : :.:...: : .::::: ::.::.::::: :.::: ::.::..::
NP_000 MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 QKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARHYPGDFSP
.::::::. :: ..::.:.:::::: ::: .:::::..:.::.:::::::: : :..:.:
NP_000 KKVADALTNAVAHVDDMPNALSALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTP
70 80 90 100 110 120
130 140
pF1KE6 ALQASLDKFLSHVISALVSEYR
:..:::::::. : ..:.:.::
NP_000 AVHASLDKFLASVSTVLTSKYR
130 140
>>NP_005323 (OMIM: 142310) hemoglobin subunit zeta [Homo (142 aa)
initn: 485 init1: 485 opt: 485 Z-score: 650.7 bits: 126.3 E(85289): 1.7e-29
Smith-Waterman score: 485; 52.1% identity (80.3% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE6 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHLDLSPGSSQVRAHG
:.:. .:... ..: :..... . ::.::: ::. : ::::: :.:: :::.:.::::
NP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 QKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARHYPGDFSP
.::. :.. ::. .::. ::: ::.::: :::::..:.::.:::::::: ..:.::.
NP_005 SKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTA
70 80 90 100 110 120
130 140
pF1KE6 ALQASLDKFLSHVISALVSEYR
.:. ::::: : :.:. .::
NP_005 EAHAAWDKFLSVVSSVLTEKYR
130 140
>>XP_005255345 (OMIM: 142310) PREDICTED: hemoglobin subu (142 aa)
initn: 485 init1: 485 opt: 485 Z-score: 650.7 bits: 126.3 E(85289): 1.7e-29
Smith-Waterman score: 485; 52.1% identity (80.3% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KE6 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHLDLSPGSSQVRAHG
:.:. .:... ..: :..... . ::.::: ::. : ::::: :.:: :::.:.::::
XP_005 MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 QKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARHYPGDFSP
.::. :.. ::. .::. ::: ::.::: :::::..:.::.:::::::: ..:.::.
XP_005 SKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTA
70 80 90 100 110 120
130 140
pF1KE6 ALQASLDKFLSHVISALVSEYR
.:. ::::: : :.:. .::
XP_005 EAHAAWDKFLSVVSSVLTEKYR
130 140
>>XP_005255344 (OMIM: 142310) PREDICTED: hemoglobin subu (154 aa)
initn: 485 init1: 485 opt: 485 Z-score: 650.1 bits: 126.3 E(85289): 1.8e-29
Smith-Waterman score: 485; 52.1% identity (80.3% similar) in 142 aa overlap (1-142:13-154)
10 20 30 40
pF1KE6 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHLD
:.:. .:... ..: :..... . ::.::: ::. : ::::: :.:
XP_005 MTCFFDAAHPAAMSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 LSPGSSQVRAHGQKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLV
: :::.:.::::.::. :.. ::. .::. ::: ::.::: :::::..:.::.:::::
XP_005 LHPGSAQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLV
70 80 90 100 110 120
110 120 130 140
pF1KE6 TLARHYPGDFSPALQASLDKFLSHVISALVSEYR
::: ..:.::. .:. ::::: : :.:. .::
XP_005 TLAARFPADFTAEAHAAWDKFLSVVSSVLTEKYR
130 140 150
>>NP_001003938 (OMIM: 609639) hemoglobin subunit mu [Hom (141 aa)
initn: 364 init1: 364 opt: 364 Z-score: 490.9 bits: 96.7 E(85289): 1.3e-20
Smith-Waterman score: 364; 41.4% identity (70.7% similar) in 140 aa overlap (3-142:2-141)
10 20 30 40 50 60
pF1KE6 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHLDLSPGSSQVRAHG
:::..:: . .: .... . . .: : : : ..:.::.:: ::. ..:. .::
NP_001 MLSAQERAQIAQVWDLIAGHEAQFGAELLLRLFTVYPSTKVYFPHLSACQDATQLLSHG
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 QKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARHYPGDFSP
:.. :.. ::...:.: ::: :. ::: ::::::.: :: .:. :.:: : .:.
NP_001 QRMLAAVGAAVQHVDNLRAALSPLADLHALVLRVDPANFPLLIQCFHVVLASHLQDEFTV
60 70 80 90 100 110
130 140
pF1KE6 ALQASLDKFLSHVISALVSEYR
.::. ::::. : .:. .::
NP_001 QMQAAWDKFLTGVAVVLTEKYR
120 130 140
>>NP_000175 (OMIM: 141749,142250,613977) hemoglobin subu (147 aa)
initn: 279 init1: 243 opt: 322 Z-score: 435.2 bits: 86.4 E(85289): 1.7e-17
Smith-Waterman score: 322; 39.3% identity (71.0% similar) in 145 aa overlap (3-141:4-146)
10 20 30 40 50
pF1KE6 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHL-DLSP-----GS
.. ::.: . .:: :. :: :.: : ....: :. .:. . .:: :.
NP_000 MGHFTEEDKATITSLWGKV--NVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 SQVRAHGQKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARH
.:.:::.:: .:. :...:::: ... ::.:: .:.::: .:.:::. :...:: :
NP_000 PKVKAHGKKVLTSLGDAIKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
60 70 80 90 100 110
120 130 140
pF1KE6 YPGDFSPALQASLDKFLSHVISALVSEYR
. .:.: .::: .:... : ::: :.:
NP_000 FGKEFTPEVQASWQKMVTGVASALSSRYH
120 130 140
>>NP_000510 (OMIM: 142000) hemoglobin subunit delta [Hom (147 aa)
initn: 316 init1: 226 opt: 321 Z-score: 433.8 bits: 86.2 E(85289): 2e-17
Smith-Waterman score: 321; 40.7% identity (70.3% similar) in 145 aa overlap (3-141:4-146)
10 20 30 40 50
pF1KE6 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYF-SHLDLS-P----GS
:. :... : ::: :. :: . ::: : ....: :. .: : ::: : :.
NP_000 MVHLTPEEKTAVNALWGKV--NVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 SQVRAHGQKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARH
.:.:::.:: :.: .. .::.: ..: ::.:: .:.::: .:.:::. :. .:::.
NP_000 PKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVDPENFRLLGNVLVCVLARN
60 70 80 90 100 110
120 130 140
pF1KE6 YPGDFSPALQASLDKFLSHVISALVSEYR
. .:.: .::. .: .. : .::. .:
NP_000 FGKEFTPQMQAAYQKVVAGVANALAHKYH
120 130 140
>>NP_000550 (OMIM: 141749,142200) hemoglobin subunit gam (147 aa)
initn: 275 init1: 239 opt: 318 Z-score: 429.9 bits: 85.5 E(85289): 3.3e-17
Smith-Waterman score: 318; 39.3% identity (71.0% similar) in 145 aa overlap (3-141:4-146)
10 20 30 40 50
pF1KE6 MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHL-DLSP-----GS
.. ::.: . .:: :. :: :.: : ....: :. .:. . .:: :.
NP_000 MGHFTEEDKATITSLWGKV--NVEDAGGETLGRLLVVYPWTQRFFDSFGNLSSASAIMGN
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 SQVRAHGQKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARH
.:.:::.:: .:. :...:::: ... ::.:: .:.::: .:.:::. :...:: :
NP_000 PKVKAHGKKVLTSLGDATKHLDDLKGTFAQLSELHCDKLHVDPENFKLLGNVLVTVLAIH
60 70 80 90 100 110
120 130 140
pF1KE6 YPGDFSPALQASLDKFLSHVISALVSEYR
. .:.: .::: .:... : ::: :.:
NP_000 FGKEFTPEVQASWQKMVTAVASALSSRYH
120 130 140
142 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:09:57 2016 done: Tue Nov 8 10:09:58 2016
Total Scan time: 3.870 Total Display time: -0.040
Function used was FASTA [36.3.4 Apr, 2011]