Result of FASTA (omim) for
pFN21AB7612
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7612, 359 aa
1>>>pF1KB7612 359 - 359 aa - 359 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6706+/-0.000386; mu= 20.0800+/- 0.025
mean_var=234.0090+/-49.521, 0's: 0 Z-trim(120.2): 300 B-trim: 25 in 1/56
Lambda= 0.083841
statistics sampled from 34750 (35115) to 34750 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.412), width: 16
Scan time: 7.480
The best scores are: opt bits E(85289)
NP_665804 (OMIM: 609481) insulin gene enhancer pro ( 359) 2478 312.4 1e-84
XP_016877994 (OMIM: 609481) PREDICTED: insulin gen ( 534) 2258 286.0 1.3e-76
NP_002193 (OMIM: 600366) insulin gene enhancer pro ( 349) 1872 239.0 1.2e-62
XP_011541682 (OMIM: 600366) PREDICTED: insulin gen ( 285) 1412 183.2 6e-46
NP_001167617 (OMIM: 161200,602575) LIM homeobox tr ( 406) 638 89.9 1.1e-17
NP_002307 (OMIM: 161200,602575) LIM homeobox trans ( 395) 621 87.8 4.5e-17
NP_001167618 (OMIM: 161200,602575) LIM homeobox tr ( 402) 620 87.7 4.9e-17
NP_001167540 (OMIM: 600298) LIM homeobox transcrip ( 382) 612 86.7 9.3e-17
NP_796372 (OMIM: 600298) LIM homeobox transcriptio ( 382) 612 86.7 9.3e-17
XP_011507842 (OMIM: 600298) PREDICTED: LIM homeobo ( 279) 609 86.1 1e-16
XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobo ( 336) 522 75.7 1.7e-13
XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobo ( 378) 514 74.8 3.4e-13
NP_001014434 (OMIM: 606066) LIM/homeobox protein L ( 388) 514 74.9 3.5e-13
NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 ( 397) 514 74.9 3.5e-13
XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobo ( 403) 514 74.9 3.5e-13
XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobo ( 314) 461 68.3 2.7e-11
XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/ ( 386) 462 68.6 2.7e-11
NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 ( 406) 461 68.5 3e-11
NP_055379 (OMIM: 221750,600577) LIM/homeobox prote ( 402) 458 68.1 3.9e-11
XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/ ( 373) 457 67.9 4.1e-11
NP_835258 (OMIM: 221750,600577) LIM/homeobox prote ( 397) 457 68.0 4.2e-11
NP_203129 (OMIM: 262700,602146) LIM/homeobox prote ( 390) 435 65.3 2.6e-10
NP_001243043 (OMIM: 604425) LIM/homeobox protein L ( 346) 426 64.1 5.3e-10
NP_001001933 (OMIM: 604425) LIM/homeobox protein L ( 356) 426 64.1 5.3e-10
XP_016856806 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363) 426 64.2 5.4e-10
XP_016856805 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363) 426 64.2 5.4e-10
XP_011507840 (OMIM: 600298) PREDICTED: LIM homeobo ( 302) 422 63.5 6.9e-10
NP_001229263 (OMIM: 608215) LIM/homeobox protein L ( 363) 411 62.3 1.9e-09
NP_001229262 (OMIM: 608215) LIM/homeobox protein L ( 366) 411 62.4 1.9e-09
NP_954629 (OMIM: 608215) LIM/homeobox protein Lhx6 ( 377) 411 62.4 1.9e-09
XP_011516824 (OMIM: 608215) PREDICTED: LIM/homeobo ( 378) 411 62.4 1.9e-09
NP_055183 (OMIM: 608215) LIM/homeobox protein Lhx6 ( 392) 411 62.4 2e-09
XP_011516823 (OMIM: 608215) PREDICTED: LIM/homeobo ( 407) 411 62.4 2e-09
XP_005251973 (OMIM: 608215) PREDICTED: LIM/homeobo ( 230) 406 61.4 2.3e-09
NP_071758 (OMIM: 605992) LIM/homeobox protein Lhx5 ( 402) 409 62.2 2.4e-09
NP_005559 (OMIM: 601999) LIM/homeobox protein Lhx1 ( 406) 409 62.2 2.4e-09
XP_005271348 (OMIM: 603129) PREDICTED: LIM domain ( 165) 395 59.8 5e-09
NP_006760 (OMIM: 603129) LIM domain transcription ( 165) 395 59.8 5e-09
NP_061110 (OMIM: 180386) LIM domain only protein 3 ( 145) 377 57.5 2.1e-08
XP_006719173 (OMIM: 180386) PREDICTED: LIM domain ( 145) 377 57.5 2.1e-08
NP_001230539 (OMIM: 180386) LIM domain only protei ( 145) 377 57.5 2.1e-08
NP_001230538 (OMIM: 180386) LIM domain only protei ( 145) 377 57.5 2.1e-08
XP_011519065 (OMIM: 180386) PREDICTED: LIM domain ( 145) 377 57.5 2.1e-08
NP_001001395 (OMIM: 180386) LIM domain only protei ( 145) 377 57.5 2.1e-08
XP_006719174 (OMIM: 180386) PREDICTED: LIM domain ( 145) 377 57.5 2.1e-08
XP_011519064 (OMIM: 180386) PREDICTED: LIM domain ( 145) 377 57.5 2.1e-08
NP_001230540 (OMIM: 180386) LIM domain only protei ( 156) 377 57.6 2.2e-08
NP_001230541 (OMIM: 180386) LIM domain only protei ( 163) 377 57.6 2.2e-08
XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 370 56.7 3.8e-08
XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 370 56.7 3.8e-08
>>NP_665804 (OMIM: 609481) insulin gene enhancer protein (359 aa)
initn: 2478 init1: 2478 opt: 2478 Z-score: 1641.9 bits: 312.4 E(85289): 1e-84
Smith-Waterman score: 2478; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359)
10 20 30 40 50 60
pF1KB7 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 YLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 YLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 SRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 RPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 NKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 NKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPP
250 260 270 280 290 300
310 320 330 340 350
pF1KB7 WKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 WKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET
310 320 330 340 350
>>XP_016877994 (OMIM: 609481) PREDICTED: insulin gene en (534 aa)
initn: 2240 init1: 2240 opt: 2258 Z-score: 1496.6 bits: 286.0 E(85289): 1.3e-76
Smith-Waterman score: 2258; 93.2% identity (95.5% similar) in 354 aa overlap (1-354:1-349)
10 20 30 40 50 60
pF1KB7 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 YLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 SRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLPDAGSGRQPAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 NKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQPP
250 260 270 280 290 300
310 320 330 340 350
pF1KB7 WKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET
::::::::::::::::::::: .: :. : :. :... : .: . ::
XP_016 WKALSEFALQSDLDQPAFQQLGLLSA----GGRSPRDTFRLGARGPGAP-ARVPLHLPLP
310 320 330 340 350
XP_016 GVSAAPGLLLRVRLPRQLLRQRRDLPVLAAPGHPQQYGAESRGDVRGTPPCQPADLACSL
360 370 380 390 400 410
>>NP_002193 (OMIM: 600366) insulin gene enhancer protein (349 aa)
initn: 1920 init1: 1813 opt: 1872 Z-score: 1245.8 bits: 239.0 E(85289): 1.2e-62
Smith-Waterman score: 1872; 75.6% identity (91.4% similar) in 349 aa overlap (11-358:1-348)
10 20 30 40 50 60
pF1KB7 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQ
.: ::: ::: ..:::::.:::::.::::::::::::::::::::.:
NP_002 MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 YLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVC
::::.::::::::::::::::.::.:::::::..:::..:.:::::..::::::::: .:
NP_002 YLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVAC
60 70 80 90 100 110
130 140 150 160 170
pF1KB7 SRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLP-DAGSGRQPA
::::.:::::.::: :.::::: .. :::. :. .:: :: :.. . :.::::
NP_002 SRQLIPGDEFALREDGLFCRADHDVV-ERASLGAGDPLSPLHPARPLQMAAEPISARQPA
120 130 140 150 160
180 190 200 210 220 230
pF1KB7 LRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWF
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWF
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 QNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAVEVQTYQP
:::::::::.::.:::::::: .:::..::.::::.::.:: ::....:.. ::::.:::
NP_002 QNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQP
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB7 PWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSMVPSPVET
:::.::.::::::.:::::::::.:::.: .::.::.:.:.:::::::::::: ::.:
NP_002 PWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA
290 300 310 320 330 340
>>XP_011541682 (OMIM: 600366) PREDICTED: insulin gene en (285 aa)
initn: 1460 init1: 1353 opt: 1412 Z-score: 945.9 bits: 183.2 E(85289): 6e-46
Smith-Waterman score: 1412; 74.3% identity (91.3% similar) in 276 aa overlap (84-358:10-284)
60 70 80 90 100 110
pF1KB7 KCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIE
:.:::::::..:::..:.:::::..:::::
XP_011 MEPIKIVPWLYGIKCAKCSIGFSKNDFVMRARSKVYHIE
10 20 30
120 130 140 150 160 170
pF1KB7 CFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGARGLHLP-DA
:::: .:::::.:::::.::: :.::::: .. :::. :. .:: :: :.. .
XP_011 CFRCVACSRQLIPGDEFALREDGLFCRADHDVV-ERASLGAGDPLSPLHPARPLQMAAEP
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB7 GSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSP
:.:::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSP
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB7 RVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAV
::::::::::::::::.::.:::::::: .:::..::.::::.::.:: ::....:.. :
XP_011 RVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPV
160 170 180 190 200 210
300 310 320 330 340 350
pF1KB7 EVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSM
:::.::::::.::.::::::.:::::::::.:::.: .::.::.:.:.:::::::::::
XP_011 EVQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSM
220 230 240 250 260 270
pF1KB7 VPSPVET
: ::.:
XP_011 VASPIEA
280
>>NP_001167617 (OMIM: 161200,602575) LIM homeobox transc (406 aa)
initn: 466 init1: 307 opt: 638 Z-score: 438.6 bits: 89.9 E(85289): 1.1e-17
Smith-Waterman score: 638; 34.3% identity (59.0% similar) in 327 aa overlap (22-343:51-371)
10 20 30 40 50
pF1KB7 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAA
: :.: :: : :.:..::. . ::
NP_001 CAKMLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVN-ESSWHEE
30 40 50 60 70
60 70 80 90 100 110
pF1KB7 CLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYH
::.:: :.: : : .:. :: : :::.:: .::. ::. :. .. ...:::: . :::
NP_001 CLQCAACQQAL--TTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYH
80 90 100 110 120 130
120 130 140 150 160
pF1KB7 IECFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGAR--GLHL
. :: : :: ::: :::: :.: .:::..:. . .. :: . . :
NP_001 LGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMK
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB7 PDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTG
: :.: : :. .. : ::.:. .: ..... . .. .: ..: :. ::
NP_001 PAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETG
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB7 LSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQG
:: ::..:::::.: : :: . .: :.::.:.. . :: : :. . . ..:
NP_001 LSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLG-QGEPGPGQGLGQEVLS-SRMEG
260 270 280 290 300 310
290 300 310 320 330 340
pF1KB7 SAVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSE---SGSLGNSSGSDVTSLSSQLP
. :: . . . . .. ::: .. . . :. .. :: :::.:
NP_001 MMASYTPLAPPQQQIVAMEQSPYGSSDPFQQGLTPPQMPGNDSIFHDIDSD-TSLTSLSD
320 330 340 350 360 370
350
pF1KB7 DTPNSMVPSPVET
NP_001 CFLGSSDVGSLQARVGNPIDRLYSMQSSYFAS
380 390 400
>>NP_002307 (OMIM: 161200,602575) LIM homeobox transcrip (395 aa)
initn: 436 init1: 307 opt: 621 Z-score: 427.6 bits: 87.8 E(85289): 4.5e-17
Smith-Waterman score: 636; 34.4% identity (60.5% similar) in 337 aa overlap (22-345:51-378)
10 20 30 40 50
pF1KB7 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAA
: :.: :: : :.:..::. . ::
NP_002 CAKMLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVN-ESSWHEE
30 40 50 60 70
60 70 80 90 100 110
pF1KB7 CLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYH
::.:: :.: : : .:. :: : :::.:: .::. ::. :. .. ...:::: . :::
NP_002 CLQCAACQQAL--TTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYH
80 90 100 110 120 130
120 130 140 150 160
pF1KB7 IECFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGAR--GLHL
. :: : :: ::: :::: :.: .:::..:. . .. :: . . :
NP_002 LGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMK
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB7 PDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTG
: :.: : :. .. : ::.:. .: ..... . .. .: ..: :. ::
NP_002 PAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETG
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB7 LSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDK-------TSLQGLTG--TPLVAGSP
:: ::..:::::.: : :: . .: :.::.:.. . ..:. . :::. .
NP_002 LSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQ
260 270 280 290 300 310
290 300 310 320 330
pF1KB7 --IRHENAVQGSAVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDV
. :.. ::. : : . .. .. :.:. . .:.:.:. ::.: ::
NP_002 QIVAMEQSPYGSSDPFQQGLTPPQMPGNDSIFHDIDSDT--SLTSLSDC-FLGSS---DV
320 330 340 350 360 370
340 350
pF1KB7 TSLSSQLPDTPNSMVPSPVET
::....
NP_002 GSLQARVGNPIDRLYSMQSSYFAS
380 390
>>NP_001167618 (OMIM: 161200,602575) LIM homeobox transc (402 aa)
initn: 445 init1: 307 opt: 620 Z-score: 426.9 bits: 87.7 E(85289): 4.9e-17
Smith-Waterman score: 625; 33.6% identity (60.5% similar) in 339 aa overlap (22-345:51-385)
10 20 30 40 50
pF1KB7 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAA
: :.: :: : :.:..::. . ::
NP_001 CAKMLDGIKMEEHALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVN-ESSWHEE
30 40 50 60 70
60 70 80 90 100 110
pF1KB7 CLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYH
::.:: :.: : : .:. :: : :::.:: .::. ::. :. .. ...:::: . :::
NP_001 CLQCAACQQAL--TTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYH
80 90 100 110 120 130
120 130 140 150 160
pF1KB7 IECFRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSPGPLPGAR--GLHL
. :: : :: ::: :::: :.: .:::..:. . .. :: . . :
NP_001 LGCFCCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMK
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB7 PDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTG
: :.: : :. .. : ::.:. .: ..... . .. .: ..: :. ::
NP_001 PAKGQGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETG
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB7 LSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTP---LVAGSPIRHENA
:: ::..:::::.: : :: . .: :.::.:.. . . :.. ... .:. .
NP_001 LSVRVVQVWFQNQRAKMKKLARRHQQQQEQQNSQRLGQEVLSSRMEGMMASYTPLAPPQQ
260 270 280 290 300 310
290 300 310 320 330
pF1KB7 VQGSAVEVQTY---QPPWKALSEFALQSDLDQP-----AFQQLVSFSESGSLGNS--SGS
: :.: . : .: ..:. . .: .: :... : . ::.. ..:
NP_001 -QIVAMEQSPYGSSDPFQQGLTPPQMPGDHMNPYGNDSIFHDIDSDTSLTSLSDCFLGSS
320 330 340 350 360 370
340 350
pF1KB7 DVTSLSSQLPDTPNSMVPSPVET
:: ::....
NP_001 DVGSLQARVGNPIDRLYSMQSSYFAS
380 390 400
>>NP_001167540 (OMIM: 600298) LIM homeobox transcription (382 aa)
initn: 535 init1: 322 opt: 612 Z-score: 421.8 bits: 86.7 E(85289): 9.3e-17
Smith-Waterman score: 612; 38.7% identity (64.1% similar) in 256 aa overlap (25-278:33-278)
10 20 30 40 50
pF1KB7 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLK
..: :: : :.:.::.. : :: :..
NP_001 DGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLN-DSFWHEQCVQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 CAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIEC
:: :.. :. : :: :: : ::: :: .::..::. : ... ...::::. ::::. :
NP_001 CASCKEPLETT--CFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSC
70 80 90 100 110
120 130 140 150 160 170
pF1KB7 FRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSP--GPLPGARGLHLPDA
: : :: ::: :::: :.: .:::..:. : . :: . : ..:
NP_001 FCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 GSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSP
:.:. : . . :: . : ::.:. .: ..... . .. .: ..: :. ::::
NP_001 GAGKGTAEEGKDHK---RPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 RVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAV
::..:::::.: : :: . . ::::..:. . : :... .:
NP_001 RVVQVWFQNQRAKMKK----LARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 EVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSM
NP_001 LPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCF
300 310 320 330 340 350
>>NP_796372 (OMIM: 600298) LIM homeobox transcription fa (382 aa)
initn: 535 init1: 322 opt: 612 Z-score: 421.8 bits: 86.7 E(85289): 9.3e-17
Smith-Waterman score: 612; 38.7% identity (64.1% similar) in 256 aa overlap (25-278:33-278)
10 20 30 40 50
pF1KB7 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLK
..: :: : :.:.::.. : :: :..
NP_796 DGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLN-DSFWHEQCVQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 CAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIEC
:: :.. :. : :: :: : ::: :: .::..::. : ... ...::::. ::::. :
NP_796 CASCKEPLETT--CFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSC
70 80 90 100 110
120 130 140 150 160 170
pF1KB7 FRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSP--GPLPGARGLHLPDA
: : :: ::: :::: :.: .:::..:. : . :: . : ..:
NP_796 FCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 GSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSP
:.:. : . . :: . : ::.:. .: ..... . .. .: ..: :. ::::
NP_796 GAGKGTAEEGKDHK---RPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 RVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAV
::..:::::.: : :: . . ::::..:. . : :... .:
NP_796 RVVQVWFQNQRAKMKK----LARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 EVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSM
NP_796 LPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCF
300 310 320 330 340 350
>>XP_011507842 (OMIM: 600298) PREDICTED: LIM homeobox tr (279 aa)
initn: 550 init1: 322 opt: 609 Z-score: 421.0 bits: 86.1 E(85289): 1e-16
Smith-Waterman score: 609; 39.4% identity (64.7% similar) in 249 aa overlap (25-271:33-271)
10 20 30 40 50
pF1KB7 MVDIIFHYPFLGAMGDHSKKKPGTAMCVGCGSQIHDQFILRVSPDLEWHAACLK
..: :: : :.:.::.. : :: :..
XP_011 DGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLN-DSFWHEQCVQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 CAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCQVGFSSSDLVMRARDSVYHIEC
:: :.. :. : :: :: : ::: :: .::..::. : ... ...::::. ::::. :
XP_011 CASCKEPLETT--CFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSC
70 80 90 100 110
120 130 140 150 160 170
pF1KB7 FRCSVCSRQLLPGDEFSLREHELLCRADHGLLLERAAAGSPRSP--GPLPGARGLHLPDA
: : :: ::: :::: :.: .:::..:. : . :: . : ..:
XP_011 FCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 GSGRQPALRPHVHKQTEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSP
:.:. : . . ::. . : ::.:. .: ..... . .. .: ..: :. ::::
XP_011 GAGKGTAEEGKDHKRPK---RPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 RVIRVWFQNKRCKDKKKSILMKQLQQQQHSDKTSLQGLTGTPLVAGSPIRHENAVQGSAV
::..:::::.: : :: . . ::::..:. . : :.
XP_011 RVVQVWFQNQRAKMKK----LARRQQQQQQDQQNTQRLSSDWCSHTC
240 250 260 270
300 310 320 330 340 350
pF1KB7 EVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSLGNSSGSDVTSLSSQLPDTPNSM
359 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 01:28:55 2016 done: Tue Nov 8 01:28:56 2016
Total Scan time: 7.480 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]