Result of FASTA (omim) for
pFN21AE3073
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3073, 234 aa
1>>>pF1KE3073 234 - 234 aa - 234 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0627+/-0.00044; mu= 15.5454+/- 0.027
mean_var=59.3107+/-12.169, 0's: 0 Z-trim(108.9): 66 B-trim: 1005 in 1/47
Lambda= 0.166536
statistics sampled from 17013 (17044) to 17013 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.574), E-opt: 0.2 (0.2), width: 16
Scan time: 5.970
The best scores are: opt bits E(85289)
NP_075601 (OMIM: 608338) ubiquitin thioesterase OT ( 234) 1526 375.2 5.4e-104
XP_005268112 (OMIM: 608338) PREDICTED: ubiquitin t ( 235) 1519 373.5 1.7e-103
XP_011535450 (OMIM: 608338) PREDICTED: ubiquitin t ( 252) 1519 373.5 1.9e-103
NP_060140 (OMIM: 608337) ubiquitin thioesterase OT ( 271) 728 183.5 3.2e-46
>>NP_075601 (OMIM: 608338) ubiquitin thioesterase OTUB2 (234 aa)
initn: 1526 init1: 1526 opt: 1526 Z-score: 1988.0 bits: 375.2 E(85289): 5.4e-104
Smith-Waterman score: 1526; 100.0% identity (100.0% similar) in 234 aa overlap (1-234:1-234)
10 20 30 40 50 60
pF1KE3 MSETSFNLISEKCDILSILRDHPENRIYRRKIEELSKRFTAIRKTKGDGNCFYRALGYSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 MSETSFNLISEKCDILSILRDHPENRIYRRKIEELSKRFTAIRKTKGDGNCFYRALGYSY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LESLLGKSREIFKFKERVLQTPNDLLAAGFEEHKFRNFFNAFYSVVELVEKDGSVSSLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 LESLLGKSREIFKFKERVLQTPNDLLAAGFEEHKFRNFFNAFYSVVELVEKDGSVSSLLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VFNDQSASDHIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMATECDHIQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 VFNDQSASDHIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMATECDHIQI
130 140 150 160 170 180
190 200 210 220 230
pF1KE3 TALSQALSIALQVEYVDEMDTALNHHVFPEAATPSVYLLYKTSHYNILYAADKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 TALSQALSIALQVEYVDEMDTALNHHVFPEAATPSVYLLYKTSHYNILYAADKH
190 200 210 220 230
>>XP_005268112 (OMIM: 608338) PREDICTED: ubiquitin thioe (235 aa)
initn: 1519 init1: 1519 opt: 1519 Z-score: 1978.9 bits: 373.5 E(85289): 1.7e-103
Smith-Waterman score: 1519; 100.0% identity (100.0% similar) in 233 aa overlap (2-234:3-235)
10 20 30 40 50
pF1KE3 MSETSFNLISEKCDILSILRDHPENRIYRRKIEELSKRFTAIRKTKGDGNCFYRALGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MESETSFNLISEKCDILSILRDHPENRIYRRKIEELSKRFTAIRKTKGDGNCFYRALGYS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 YLESLLGKSREIFKFKERVLQTPNDLLAAGFEEHKFRNFFNAFYSVVELVEKDGSVSSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLESLLGKSREIFKFKERVLQTPNDLLAAGFEEHKFRNFFNAFYSVVELVEKDGSVSSLL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 KVFNDQSASDHIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMATECDHIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVFNDQSASDHIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMATECDHIQ
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 ITALSQALSIALQVEYVDEMDTALNHHVFPEAATPSVYLLYKTSHYNILYAADKH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITALSQALSIALQVEYVDEMDTALNHHVFPEAATPSVYLLYKTSHYNILYAADKH
190 200 210 220 230
>>XP_011535450 (OMIM: 608338) PREDICTED: ubiquitin thioe (252 aa)
initn: 1519 init1: 1519 opt: 1519 Z-score: 1978.4 bits: 373.5 E(85289): 1.9e-103
Smith-Waterman score: 1519; 100.0% identity (100.0% similar) in 233 aa overlap (2-234:20-252)
10 20 30 40
pF1KE3 MSETSFNLISEKCDILSILRDHPENRIYRRKIEELSKRFTAI
:::::::::::::::::::::::::::::::::::::::::
XP_011 MLLWTLSPQDQELDGELSWSETSFNLISEKCDILSILRDHPENRIYRRKIEELSKRFTAI
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RKTKGDGNCFYRALGYSYLESLLGKSREIFKFKERVLQTPNDLLAAGFEEHKFRNFFNAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKTKGDGNCFYRALGYSYLESLLGKSREIFKFKERVLQTPNDLLAAGFEEHKFRNFFNAF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 YSVVELVEKDGSVSSLLKVFNDQSASDHIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSVVELVEKDGSVSSLLKVFNDQSASDHIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKD
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 FCTHEVEPMATECDHIQITALSQALSIALQVEYVDEMDTALNHHVFPEAATPSVYLLYKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FCTHEVEPMATECDHIQITALSQALSIALQVEYVDEMDTALNHHVFPEAATPSVYLLYKT
190 200 210 220 230 240
230
pF1KE3 SHYNILYAADKH
::::::::::::
XP_011 SHYNILYAADKH
250
>>NP_060140 (OMIM: 608337) ubiquitin thioesterase OTUB1 (271 aa)
initn: 708 init1: 598 opt: 728 Z-score: 950.8 bits: 183.5 E(85289): 3.2e-46
Smith-Waterman score: 728; 47.8% identity (79.5% similar) in 224 aa overlap (8-229:47-270)
10 20 30
pF1KE3 MSETSFNLISEKCDILSILRDHPEN-RIYRRKIEELS
:.::. .. . ... :. ::..::..:
NP_060 DSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLH
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE3 KRFTAIRKTKGDGNCFYRALGYSYLESLLGKSREIFKFKERVLQTPNDLLAAGFEEHKFR
:... ::::. ::::::::.:.:.::.:: :.:. .:: .. .::.. :: : ..
NP_060 KKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQGFTEFTIE
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE3 NFFNAFYSVVELVEKDGSVSSLLKVFNDQSASDHIVQFLRLLTSAFIRNRADFFRHFIDE
.: :.:....: :::. ::..:: :::::.::..: .::::::.... .. ::.:::.
NP_060 DFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE3 EMDIKDFCTHEVEPMATECDHIQITALSQALSIALQVEYVDEMDTAL-NHHVFPEAATPS
.:.:: .::::: : :::.: ::.::::...::::.:. . . : :.:::.. :.
NP_060 GRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDRGEGGTTNPHIFPEGSEPK
200 210 220 230 240 250
220 230
pF1KE3 VYLLYKTSHYNILYAADKH
:::::. .::.:::
NP_060 VYLLYRPGHYDILYK
260 270
234 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 05:19:02 2016 done: Sun Nov 6 05:19:03 2016
Total Scan time: 5.970 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]