Result of FASTA (omim) for
pFN21AE3990
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3990, 208 aa
1>>>pF1KE3990 208 - 208 aa - 208 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3485+/-0.000345; mu= 14.6267+/- 0.022
mean_var=90.3577+/-17.977, 0's: 0 Z-trim(117.9): 391 B-trim: 1366 in 2/52
Lambda= 0.134925
statistics sampled from 29913 (30377) to 29913 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.356), width: 16
Scan time: 5.650
The best scores are: opt bits E(85289)
NP_057614 (OMIM: 613532) ras-related protein Rab-8 ( 207) 495 105.7 5.7e-23
NP_005361 (OMIM: 165040) ras-related protein Rab-8 ( 207) 492 105.1 8.5e-23
XP_011526322 (OMIM: 165040) PREDICTED: ras-related ( 215) 492 105.1 8.8e-23
NP_057215 (OMIM: 612672) ras-related protein Rab-1 ( 200) 487 104.1 1.6e-22
NP_002861 (OMIM: 602672) ras-related protein Rab-1 ( 203) 480 102.7 4.2e-22
NP_001161078 (OMIM: 604199) ras-related protein Ra ( 152) 476 101.8 5.9e-22
NP_112243 (OMIM: 612565) ras-related protein Rab-1 ( 201) 469 100.6 1.9e-21
XP_016873867 (OMIM: 612565) PREDICTED: ras-related ( 237) 468 100.5 2.4e-21
NP_004152 (OMIM: 179508) ras-related protein Rab-1 ( 205) 465 99.8 3.2e-21
NP_006852 (OMIM: 604199) ras-related protein Rab-3 ( 201) 454 97.7 1.4e-20
NP_055168 (OMIM: 605455) ras-related protein Rab-2 ( 256) 426 92.3 7.3e-19
XP_011520750 (OMIM: 605455) PREDICTED: ras-related ( 231) 420 91.1 1.5e-18
NP_001006639 (OMIM: 609956) ras-related protein Ra ( 223) 408 88.8 7.5e-18
NP_001193765 (OMIM: 605570) ras-related protein Ra ( 155) 397 86.5 2.6e-17
XP_011519971 (OMIM: 613532) PREDICTED: ras-related ( 122) 394 85.8 3.2e-17
NP_004654 (OMIM: 605570) ras-related protein Rab-1 ( 216) 397 86.6 3.2e-17
NP_004209 (OMIM: 604198) ras-related protein Rab-1 ( 218) 397 86.6 3.3e-17
NP_001317400 (OMIM: 609956) ras-related protein Ra ( 196) 396 86.4 3.5e-17
NP_001157461 (OMIM: 609956) ras-related protein Ra ( 228) 396 86.4 3.9e-17
NP_001294982 (OMIM: 605455) ras-related protein Ra ( 190) 395 86.2 3.9e-17
NP_001272989 (OMIM: 605693) ras-related protein Ra ( 203) 395 86.2 4.1e-17
NP_055303 (OMIM: 605693) ras-related protein Rab-3 ( 203) 395 86.2 4.1e-17
NP_001272990 (OMIM: 605693) ras-related protein Ra ( 203) 395 86.2 4.1e-17
NP_001272988 (OMIM: 605693) ras-related protein Ra ( 203) 395 86.2 4.1e-17
NP_116235 (OMIM: 607466) ras-related protein Rab-2 ( 216) 381 83.5 2.8e-16
NP_001020471 (OMIM: 616448) ras-related protein Ra ( 244) 381 83.5 3.1e-16
NP_057238 (OMIM: 612945) ras-related protein Rab-4 ( 213) 380 83.3 3.2e-16
NP_001304844 (OMIM: 612829) ras-related protein Ra ( 225) 380 83.3 3.3e-16
NP_612462 (OMIM: 612829) ras-related protein Rab-3 ( 227) 380 83.3 3.3e-16
NP_002856 (OMIM: 179509) ras-related protein Rab-2 ( 212) 378 82.9 4.1e-16
XP_011519340 (OMIM: 614178) PREDICTED: EF-hand cal ( 493) 380 83.6 5.8e-16
XP_011519339 (OMIM: 614178) PREDICTED: EF-hand cal ( 493) 380 83.6 5.8e-16
NP_057406 (OMIM: 612673) ras-related protein Rab-1 ( 215) 375 82.3 6.3e-16
XP_016857447 (OMIM: 179510) PREDICTED: ras-related ( 219) 375 82.3 6.4e-16
NP_002858 (OMIM: 179510) ras-related protein Rab-3 ( 219) 375 82.3 6.4e-16
XP_011526466 (OMIM: 179490) PREDICTED: ras-related ( 220) 375 82.3 6.4e-16
NP_002857 (OMIM: 179490) ras-related protein Rab-3 ( 220) 375 82.3 6.4e-16
NP_004274 (OMIM: 604350) ras-related protein Rab-3 ( 219) 374 82.1 7.3e-16
NP_001138430 (OMIM: 614178) EF-hand calcium-bindin ( 731) 380 83.8 7.7e-16
XP_006719084 (OMIM: 614178) PREDICTED: EF-hand cal ( 732) 380 83.8 7.7e-16
XP_011519338 (OMIM: 614178) PREDICTED: EF-hand cal ( 732) 380 83.8 7.7e-16
XP_011519336 (OMIM: 614178) PREDICTED: EF-hand cal ( 732) 380 83.8 7.7e-16
NP_004569 (OMIM: 179511) ras-related protein Rab-4 ( 218) 373 81.9 8.3e-16
NP_001243340 (OMIM: 602207,614222) ras-related pro ( 197) 371 81.5 1e-15
NP_067075 (OMIM: 602207,614222) ras-related protei ( 206) 371 81.5 1e-15
NP_783865 (OMIM: 609956) ras-related protein Rab-3 ( 216) 370 81.4 1.2e-15
NP_741995 (OMIM: 300774) ras-related protein Rab-3 ( 213) 347 76.9 2.7e-14
XP_005251788 (OMIM: 611344) PREDICTED: ras and EF- ( 611) 352 78.3 3e-14
NP_065120 (OMIM: 612942) ras-related protein Rab-2 ( 213) 346 76.7 3.1e-14
XP_005251787 (OMIM: 611344) PREDICTED: ras and EF- ( 717) 352 78.3 3.3e-14
>>NP_057614 (OMIM: 613532) ras-related protein Rab-8B [H (207 aa)
initn: 495 init1: 495 opt: 495 Z-score: 533.4 bits: 105.7 E(85289): 5.7e-23
Smith-Waterman score: 495; 63.0% identity (89.8% similar) in 108 aa overlap (1-108:1-108)
10 20 30 40 50 60
pF1KE3 MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQ
::: :: ::.::::::::::::::: ::... :... :::::.:::..:::.:: :...:
NP_057 MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 IWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEVGDATSLPGCGE
:::::::::..::: ::: :.::.:::::..:.:...: .:. ...:
NP_057 IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GASPGKARRGPDGKANASRKLCLPQPWMKTSGTHQKASRRSLLGIRLMRSRNGRWEESKG
NP_057 NKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDS
130 140 150 160 170 180
>>NP_005361 (OMIM: 165040) ras-related protein Rab-8A [H (207 aa)
initn: 511 init1: 492 opt: 492 Z-score: 530.2 bits: 105.1 E(85289): 8.5e-23
Smith-Waterman score: 492; 60.7% identity (89.3% similar) in 112 aa overlap (1-112:1-112)
10 20 30 40 50 60
pF1KE3 MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQ
::: :: ::.:::::::::::::.: ::... :.:. :::::.:::..:::.:: ....:
NP_005 MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 IWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEVGDATSLPGCGE
:::::::::..::: ::: :.::.:::::..:.:...: .:. ...: ..:
NP_005 IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GASPGKARRGPDGKANASRKLCLPQPWMKTSGTHQKASRRSLLGIRLMRSRNGRWEESKG
NP_005 NKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGN
130 140 150 160 170 180
>>XP_011526322 (OMIM: 165040) PREDICTED: ras-related pro (215 aa)
initn: 508 init1: 492 opt: 492 Z-score: 530.0 bits: 105.1 E(85289): 8.8e-23
Smith-Waterman score: 492; 60.7% identity (89.3% similar) in 112 aa overlap (1-112:1-112)
10 20 30 40 50 60
pF1KE3 MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQ
::: :: ::.:::::::::::::.: ::... :.:. :::::.:::..:::.:: ....:
XP_011 MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 IWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEVGDATSLPGCGE
:::::::::..::: ::: :.::.:::::..:.:...: .:. ...: ..:
XP_011 IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GASPGKARRGPDGKANASRKLCLPQPWMKTSGTHQKASRRSLLGIRLMRSRNGRWEESKG
XP_011 NKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLGQK
130 140 150 160 170 180
>>NP_057215 (OMIM: 612672) ras-related protein Rab-10 [H (200 aa)
initn: 484 init1: 484 opt: 487 Z-score: 525.2 bits: 104.1 E(85289): 1.6e-22
Smith-Waterman score: 487; 62.4% identity (90.8% similar) in 109 aa overlap (1-108:1-109)
10 20 30 40 50
pF1KE3 MAKQ-YDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRI
:::. ::.::.:::::::::::::.: ::.:. :... :::::.:::.::.:..: :...
NP_057 MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 QIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEVGDATSLPGCG
::::::::::..::: .::: :.::.:::::.. .:...: ::. ..::
NP_057 QIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 EGASPGKARRGPDGKANASRKLCLPQPWMKTSGTHQKASRRSLLGIRLMRSRNGRWEESK
NP_057 GNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPN
130 140 150 160 170 180
>>NP_002861 (OMIM: 602672) ras-related protein Rab-13 is (203 aa)
initn: 480 init1: 480 opt: 480 Z-score: 517.7 bits: 102.7 E(85289): 4.2e-22
Smith-Waterman score: 480; 57.1% identity (92.0% similar) in 112 aa overlap (1-112:1-112)
10 20 30 40 50 60
pF1KE3 MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQ
::: :: ::.::::::::::::::. ::....:....:::::.:::..:....: :...:
NP_002 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 IWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEVGDATSLPGCGE
.::::::::..::: ::: :.::.:::::..:.:...:..:.... : ..:
NP_002 VWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GASPGKARRGPDGKANASRKLCLPQPWMKTSGTHQKASRRSLLGIRLMRSRNGRWEESKG
NP_002 NKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGN
130 140 150 160 170 180
>>NP_001161078 (OMIM: 604199) ras-related protein Rab-35 (152 aa)
initn: 452 init1: 452 opt: 476 Z-score: 515.1 bits: 101.8 E(85289): 5.9e-22
Smith-Waterman score: 476; 47.6% identity (77.9% similar) in 145 aa overlap (1-142:1-145)
10 20 30 40 50 60
pF1KE3 MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQ
::..:: ::.::.::::::::. :: ::.:: : .:.:.:::::::..:.:..: ::..:
NP_001 MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQ
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 IWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDE-VGDATSLPGCG
:::::::::..:::. ::: ..:...:::..: .:. .. .:. .... :. .
NP_001 IWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILDVQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 --EGASPGKARRGPDGKANASRKLCLPQPWMKTSGTHQKASRRSLLGIRLMRSRNGRWEE
.::.: . .: : : :. . :
NP_001 LHHGAGPPSKERQPGKTAAATTERCGEAHEEQ
130 140 150
>>NP_112243 (OMIM: 612565) ras-related protein Rab-1B [H (201 aa)
initn: 468 init1: 468 opt: 469 Z-score: 506.2 bits: 100.6 E(85289): 1.9e-21
Smith-Waterman score: 469; 40.3% identity (71.3% similar) in 181 aa overlap (1-180:1-181)
10 20 30 40 50 60
pF1KE3 MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQ
: .:: ::.:::::::::::.::: ::.:. . :.:::::::::..:::.:: ...:
NP_112 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 IWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEVGDATSLPGCGE
:::::::::..:::..::: :.::..:::.....:: .. .:....:. .. .
NP_112 IWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVG
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 GASPGKARRGPDGKANASRKLCLPQPWMKTSGTHQKASRRSLLGIRL-MRSRNGRWEESK
. : ... :. . : :...::. . ..... . ...: : :
NP_112 NKSDLTTKKVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASG
130 140 150 160 170 180
180 190 200
pF1KE3 GSSWRRSMAWTSMKQVPAPTSTLKSHSRV
:
NP_112 GERPNLKIDSTPVKPAGGGCC
190 200
>>XP_016873867 (OMIM: 612565) PREDICTED: ras-related pro (237 aa)
initn: 478 init1: 461 opt: 468 Z-score: 504.2 bits: 100.5 E(85289): 2.4e-21
Smith-Waterman score: 468; 58.9% identity (88.8% similar) in 107 aa overlap (1-107:1-107)
10 20 30 40 50 60
pF1KE3 MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQ
: .:: ::.:::::::::::.::: ::.:. . :.:::::::::..:::.:: ...:
XP_016 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 IWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEVGDATSLPGCGE
:::::::::..:::..::: :.::..:::.....:: .. .:....:
XP_016 IWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GASPGKARRGPDGKANASRKLCLPQPWMKTSGTHQKASRRSLLGIRLMRSRNGRWEESKG
XP_016 NKSDLTTKKVVDNTTAKVADGPVCPGSGRWGLLPLTCSPLLFSPLLFSPLPCQEFADSLG
130 140 150 160 170 180
>>NP_004152 (OMIM: 179508) ras-related protein Rab-1A is (205 aa)
initn: 465 init1: 465 opt: 465 Z-score: 501.9 bits: 99.8 E(85289): 3.2e-21
Smith-Waterman score: 465; 57.9% identity (89.7% similar) in 107 aa overlap (1-107:4-110)
10 20 30 40 50
pF1KE3 MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKV
: .:: ::.:::::::::::.::: ::.:. . :.:::::::::..:::.:: .
NP_004 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 RIQIWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEVGDATSLPG
..::::::::::..:::..::: :.::..:::.....:.... .:....:
NP_004 KLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 CGEGASPGKARRGPDGKANASRKLCLPQPWMKTSGTHQKASRRSLLGIRLMRSRNGRWEE
NP_004 LVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGA
130 140 150 160 170 180
>>NP_006852 (OMIM: 604199) ras-related protein Rab-35 is (201 aa)
initn: 452 init1: 452 opt: 454 Z-score: 490.4 bits: 97.7 E(85289): 1.4e-20
Smith-Waterman score: 454; 55.0% identity (87.4% similar) in 111 aa overlap (1-111:1-111)
10 20 30 40 50 60
pF1KE3 MAKQYDVLFRLLLIGDSGVGKTCLLCRFTDNEFHSSHISTIGVDFKMKTIEVDGIKVRIQ
::..:: ::.::.::::::::. :: ::.:: : .:.:.:::::::..:.:..: ::..:
NP_006 MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 IWDTAGQERYQTITKQYYRRAQGIFLVYDISSERSYQHIMKWVSDVDEVGDATSLPGCGE
:::::::::..:::. ::: ..:...:::..: .:. .. .:. .... :
NP_006 IWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GASPGKARRGPDGKANASRKLCLPQPWMKTSGTHQKASRRSLLGIRLMRSRNGRWEESKG
NP_006 KNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQ
130 140 150 160 170 180
208 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:11:27 2016 done: Sun Nov 6 08:11:28 2016
Total Scan time: 5.650 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]