Result of FASTA (omim) for
pFN21AE5196
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5196, 161 aa
1>>>pF1KE5196 161 - 161 aa - 161 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2454+/-0.000292; mu= 12.5378+/- 0.018
mean_var=64.8210+/-12.665, 0's: 0 Z-trim(118.3): 23 B-trim: 63 in 1/48
Lambda= 0.159300
statistics sampled from 31043 (31066) to 31043 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.364), width: 16
Scan time: 4.170
The best scores are: opt bits E(85289)
NP_002925 (OMIM: 131410) non-secretory ribonucleas ( 161) 1141 270.2 1e-72
NP_002926 (OMIM: 131398) eosinophil cationic prote ( 160) 790 189.5 2e-48
XP_016877055 (OMIM: 601981) PREDICTED: ribonucleas ( 150) 424 105.4 3.9e-23
NP_005606 (OMIM: 601981) ribonuclease K6 precursor ( 150) 424 105.4 3.9e-23
XP_016877056 (OMIM: 601981) PREDICTED: ribonucleas ( 150) 424 105.4 3.9e-23
NP_612204 (OMIM: 612485) ribonuclease 8 precursor ( 154) 423 105.1 4.7e-23
NP_115961 (OMIM: 612484) ribonuclease 7 precursor ( 156) 415 103.3 1.7e-22
NP_002924 (OMIM: 180440) ribonuclease pancreatic p ( 156) 224 59.4 2.8e-09
NP_937878 (OMIM: 180440) ribonuclease pancreatic p ( 156) 224 59.4 2.8e-09
NP_937877 (OMIM: 180440) ribonuclease pancreatic p ( 156) 224 59.4 2.8e-09
NP_937875 (OMIM: 180440) ribonuclease pancreatic p ( 156) 224 59.4 2.8e-09
NP_001269122 (OMIM: 601030) ribonuclease 4 precurs ( 147) 179 49.1 3.4e-06
NP_919412 (OMIM: 601030) ribonuclease 4 precursor ( 147) 179 49.1 3.4e-06
NP_002928 (OMIM: 601030) ribonuclease 4 precursor ( 147) 179 49.1 3.4e-06
NP_001269121 (OMIM: 601030) ribonuclease 4 precurs ( 147) 179 49.1 3.4e-06
>>NP_002925 (OMIM: 131410) non-secretory ribonuclease pr (161 aa)
initn: 1141 init1: 1141 opt: 1141 Z-score: 1426.4 bits: 270.2 E(85289): 1e-72
Smith-Waterman score: 1141; 100.0% identity (100.0% similar) in 161 aa overlap (1-161:1-161)
10 20 30 40 50 60
pF1KE5 MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTSQQCTNAMQVINNY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTSQQCTNAMQVINNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 QRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNI
70 80 90 100 110 120
130 140 150 160
pF1KE5 SNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
:::::::::::::::::::::::::::::::::::::::::
NP_002 SNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
130 140 150 160
>>NP_002926 (OMIM: 131398) eosinophil cationic protein p (160 aa)
initn: 803 init1: 723 opt: 790 Z-score: 990.5 bits: 189.5 E(85289): 2e-48
Smith-Waterman score: 790; 68.9% identity (84.5% similar) in 161 aa overlap (1-161:1-160)
10 20 30 40 50 60
pF1KE5 MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTSQQCTNAMQVINNY
::::::::::::::::::..::::::..::::: :::: :::... .:: ::..::::
NP_002 MVPKLFTSQICLLLLLGLMGVEGSLHARPPQFTRAQWFAIQHISLNPPRCTIAMRAINNY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 QRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNI
. ::::::::: :::::::::::: .. :: :.: .:::.: .:::.::.: .:. :::
NP_002 RWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNNCHRSRFRVPLLHCDLINPGAQNI
70 80 90 100 110 120
130 140 150 160
pF1KE5 SNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
::: ::. :. ::.::::::: : : :.::::::::: :
NP_002 SNCTYADRPGRRFYVVACDNRDPR-DSPRYPVVPVHLDTTI
130 140 150 160
>>XP_016877055 (OMIM: 601981) PREDICTED: ribonuclease K6 (150 aa)
initn: 401 init1: 231 opt: 424 Z-score: 536.3 bits: 105.4 E(85289): 3.9e-23
Smith-Waterman score: 424; 46.2% identity (68.6% similar) in 156 aa overlap (10-161:3-150)
10 20 30 40 50
pF1KE5 MVPKLFTSQICLLLLLGLLAVEGS---LHVKPPQFTWAQWFETQHINMTSQQCTNAMQVI
.:. ::: ::.. : ::. : ..: :.::: :::. . ::. ::. :
XP_016 MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGI
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 NNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPS-
::: ..::.::::: .: ::. :: ...: .:. :.:::.:.. : . : ::. .
XP_016 NNYTQHCKHQNTFLHDSFQNVAAVCDLLSIVC-KNR-RHNCHQSSKPVNMTDCRLTSGKY
60 70 80 90 100 110
120 130 140 150 160
pF1KE5 PQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
:: :::. . :.::::: :. ::: : .:::::: :.
XP_016 PQ----CRYSAAAQYKFFIVACDP-PQKSDPP-YKLVPVHLDSIL
120 130 140 150
>>NP_005606 (OMIM: 601981) ribonuclease K6 precursor [Ho (150 aa)
initn: 401 init1: 231 opt: 424 Z-score: 536.3 bits: 105.4 E(85289): 3.9e-23
Smith-Waterman score: 424; 46.2% identity (68.6% similar) in 156 aa overlap (10-161:3-150)
10 20 30 40 50
pF1KE5 MVPKLFTSQICLLLLLGLLAVEGS---LHVKPPQFTWAQWFETQHINMTSQQCTNAMQVI
.:. ::: ::.. : ::. : ..: :.::: :::. . ::. ::. :
NP_005 MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGI
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 NNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPS-
::: ..::.::::: .: ::. :: ...: .:. :.:::.:.. : . : ::. .
NP_005 NNYTQHCKHQNTFLHDSFQNVAAVCDLLSIVC-KNR-RHNCHQSSKPVNMTDCRLTSGKY
60 70 80 90 100 110
120 130 140 150 160
pF1KE5 PQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
:: :::. . :.::::: :. ::: : .:::::: :.
NP_005 PQ----CRYSAAAQYKFFIVACDP-PQKSDPP-YKLVPVHLDSIL
120 130 140 150
>>XP_016877056 (OMIM: 601981) PREDICTED: ribonuclease K6 (150 aa)
initn: 401 init1: 231 opt: 424 Z-score: 536.3 bits: 105.4 E(85289): 3.9e-23
Smith-Waterman score: 424; 46.2% identity (68.6% similar) in 156 aa overlap (10-161:3-150)
10 20 30 40 50
pF1KE5 MVPKLFTSQICLLLLLGLLAVEGS---LHVKPPQFTWAQWFETQHINMTSQQCTNAMQVI
.:. ::: ::.. : ::. : ..: :.::: :::. . ::. ::. :
XP_016 MVLCFPLLLLLLVLWGPVCPLHAWPKRLTKAHWFEIQHIQPSPLQCNRAMSGI
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 NNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPS-
::: ..::.::::: .: ::. :: ...: .:. :.:::.:.. : . : ::. .
XP_016 NNYTQHCKHQNTFLHDSFQNVAAVCDLLSIVC-KNR-RHNCHQSSKPVNMTDCRLTSGKY
60 70 80 90 100 110
120 130 140 150 160
pF1KE5 PQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
:: :::. . :.::::: :. ::: : .:::::: :.
XP_016 PQ----CRYSAAAQYKFFIVACDP-PQKSDPP-YKLVPVHLDSIL
120 130 140 150
>>NP_612204 (OMIM: 612485) ribonuclease 8 precursor [Hom (154 aa)
initn: 424 init1: 265 opt: 423 Z-score: 534.9 bits: 105.1 E(85289): 4.7e-23
Smith-Waterman score: 423; 44.7% identity (71.3% similar) in 150 aa overlap (12-161:12-154)
10 20 30 40 50 60
pF1KE5 MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTSQQCTNAMQVINNY
::::::: ..: ...:: ..: .:::.:::.. . : :..::..::.:
NP_612 MAPARAGCCPLLLLLLGLWVAEVLVRAKPKDMTSSQWFKTQHVQPSPQACNSAMSIINKY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 QRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQNI
.:::. :::: :..:. .: .::..: .. ::::.: . . : .::. .
NP_612 TERCKDLNTFLHEPFSSVAITCQTPNIACKNSC--KNCHQSHGPMSLTMGELTSG---KY
70 80 90 100 110
130 140 150 160
pF1KE5 SNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
:::: . : :::::: :. :: ::.::::::...
NP_612 PNCRYKEKHLNTPYIVACDP-PQQGDPG-YPLVPVHLDKVV
120 130 140 150
>>NP_115961 (OMIM: 612484) ribonuclease 7 precursor [Hom (156 aa)
initn: 363 init1: 197 opt: 415 Z-score: 524.9 bits: 103.3 E(85289): 1.7e-22
Smith-Waterman score: 415; 42.0% identity (69.3% similar) in 150 aa overlap (12-161:13-156)
10 20 30 40 50
pF1KE5 MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINMTSQQCTNAMQVINN
::::::: ..: . .:: .: .:::. ::.. . : :..::. ::.
NP_115 MAPARAGFCPLLLLLLLGLWVAEIPVSAKPKGMTSSQWFKIQHMQPSPQACNSAMKNINK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 YQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTTPSPQN
. .:::. :::: :..:. .: .:...: .. ::::.: . : : :.::. .
NP_115 HTKRCKDLNTFLHEPFSSVAATCQTPKIACKNGD--KNCHQSHGAVSLTMCKLTSG---K
70 80 90 100 110
120 130 140 150 160
pF1KE5 ISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
:::: . : :.::: . :..: :. .:::::::..
NP_115 YPNCRYKEKRQNKSYVVAC-KPPQKKDSQQFHLVPVHLDRVL
120 130 140 150
>>NP_002924 (OMIM: 180440) ribonuclease pancreatic precu (156 aa)
initn: 281 init1: 111 opt: 224 Z-score: 287.6 bits: 59.4 E(85289): 2.8e-09
Smith-Waterman score: 243; 32.5% identity (56.2% similar) in 160 aa overlap (5-158:3-149)
10 20 30 40 50
pF1KE5 MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINM------TSQQCTNAM
: : . ::::. .: : : .. . . . :. :. ::.. .: :.. :
NP_002 MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMM
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 QVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTT
. : : ::: :::. ...: ::: . ..:: ... ::..:.:.. . : ::.
NP_002 RRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQ--GNCYKSNSSMHITDCRLTN
60 70 80 90 100 110
120 130 140 150 160
pF1KE5 PSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
: :: : .: . ::::.. : ::::.:
NP_002 GS--RYPNCAYRTSPKERHIIVACEGS---------PYVPVHFDASVEDST
120 130 140 150
>>NP_937878 (OMIM: 180440) ribonuclease pancreatic precu (156 aa)
initn: 281 init1: 111 opt: 224 Z-score: 287.6 bits: 59.4 E(85289): 2.8e-09
Smith-Waterman score: 243; 32.5% identity (56.2% similar) in 160 aa overlap (5-158:3-149)
10 20 30 40 50
pF1KE5 MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINM------TSQQCTNAM
: : . ::::. .: : : .. . . . :. :. ::.. .: :.. :
NP_937 MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMM
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 QVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTT
. : : ::: :::. ...: ::: . ..:: ... ::..:.:.. . : ::.
NP_937 RRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQ--GNCYKSNSSMHITDCRLTN
60 70 80 90 100 110
120 130 140 150 160
pF1KE5 PSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
: :: : .: . ::::.. : ::::.:
NP_937 GS--RYPNCAYRTSPKERHIIVACEGS---------PYVPVHFDASVEDST
120 130 140 150
>>NP_937877 (OMIM: 180440) ribonuclease pancreatic precu (156 aa)
initn: 281 init1: 111 opt: 224 Z-score: 287.6 bits: 59.4 E(85289): 2.8e-09
Smith-Waterman score: 243; 32.5% identity (56.2% similar) in 160 aa overlap (5-158:3-149)
10 20 30 40 50
pF1KE5 MVPKLFTSQICLLLLLGLLAVEGSLHVKPPQFTWAQWFETQHINM------TSQQCTNAM
: : . ::::. .: : : .. . . . :. :. ::.. .: :.. :
NP_937 MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMM
10 20 30 40 50
60 70 80 90 100 110
pF1KE5 QVINNYQRRCKNQNTFLLTTFANVVNVCGNPNMTCPSNKTRKNCHHSGSQVPLIHCNLTT
. : : ::: :::. ...: ::: . ..:: ... ::..:.:.. . : ::.
NP_937 RRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQ--GNCYKSNSSMHITDCRLTN
60 70 80 90 100 110
120 130 140 150 160
pF1KE5 PSPQNISNCRYAQTPANMFYIVACDNRDQRRDPPQYPVVPVHLDRII
: :: : .: . ::::.. : ::::.:
NP_937 GS--RYPNCAYRTSPKERHIIVACEGS---------PYVPVHFDASVEDST
120 130 140 150
161 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:27:19 2016 done: Mon Nov 7 22:27:19 2016
Total Scan time: 4.170 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]