Result of FASTA (ccds) for
pFN21AE2524
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2524, 457 aa
1>>>pF1KE2524 457 - 457 aa - 457 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.5765+/-0.00105; mu= -3.9002+/- 0.064
mean_var=338.5712+/-69.984, 0's: 0 Z-trim(115.2): 7 B-trim: 429 in 1/52
Lambda= 0.069703
statistics sampled from 15799 (15806) to 15799 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.486), width: 16
Scan time: 3.740
The best scores are: opt bits E(32554)
CCDS8178.1 CHKA gene_id:1119|Hs108|chr11 ( 457) 3124 327.6 1.7e-89
CCDS8179.1 CHKA gene_id:1119|Hs108|chr11 ( 439) 1912 205.7 7.9e-53
CCDS14099.1 CHKB gene_id:1120|Hs108|chr22 ( 395) 1227 136.8 4e-32
>>CCDS8178.1 CHKA gene_id:1119|Hs108|chr11 (457 aa)
initn: 3124 init1: 3124 opt: 3124 Z-score: 1720.3 bits: 327.6 E(32554): 1.7e-89
Smith-Waterman score: 3124; 100.0% identity (100.0% similar) in 457 aa overlap (1-457:1-457)
10 20 30 40 50 60
pF1KE2 MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 PPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 SNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENEFQGAEAMVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENEFQGAEAMVLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 PFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 PFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 VFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 FFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 FFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLW
370 380 390 400 410 420
430 440 450
pF1KE2 GLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
:::::::::::::::::::::::::::::::::::::
CCDS81 GLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
430 440 450
>>CCDS8179.1 CHKA gene_id:1119|Hs108|chr11 (439 aa)
initn: 2988 init1: 1902 opt: 1912 Z-score: 1061.9 bits: 205.7 E(32554): 7.9e-53
Smith-Waterman score: 2956; 96.1% identity (96.1% similar) in 457 aa overlap (1-457:1-439)
10 20 30 40 50 60
pF1KE2 MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 PPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 PPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 SNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENEFQGAEAMVLE
:::::::::::::::::::::::::::::::::: ::::::::
CCDS81 SNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQM------------------GAEAMVLE
130 140 150 160
190 200 210 220 230 240
pF1KE2 SVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKM
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE2 PFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 PFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE2 VFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYP
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE2 FFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 FFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLW
350 360 370 380 390 400
430 440 450
pF1KE2 GLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
:::::::::::::::::::::::::::::::::::::
CCDS81 GLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
410 420 430
>>CCDS14099.1 CHKB gene_id:1120|Hs108|chr22 (395 aa)
initn: 1047 init1: 456 opt: 1227 Z-score: 690.2 bits: 136.8 E(32554): 4e-32
Smith-Waterman score: 1475; 57.9% identity (77.7% similar) in 385 aa overlap (74-455:29-388)
50 60 70 80 90 100
pF1KE2 ESKQLGGQQPPLALPPPPPLPLPLPLPQPPPPQPPADEQPEPRTR---RRAYLWCKEFLP
: : .. .: :::: ::.:.:
CCDS14 MAAEATAVAGSGAVGGCLAKDGLQQSKCPDTTPKRRRASSLSRDAERRAYQWCREYLG
10 20 30 40 50
110 120 130 140 150 160
pF1KE2 GAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKE
:::: .. .:... . :::::.::.::::: ..:.:::.:::::::::::
CCDS14 GAWRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQ-------
60 70 80 90 100 110
170 180 190 200 210 220
pF1KE2 GSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELS
:....:::::::::::::::::.:::.::.:::::.:::: : :.::
CCDS14 ------------GVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELR
120 130 140 150
230 240 250 260 270 280
pF1KE2 LPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSY
: .:: :: ::: ::::.:::.:::.:::::::.:::.. . : . ... : :
CCDS14 EPVLSAAIATKMAQFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPT---GLPEMNLLEMY
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE2 NLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRG
.: :. :::.::::::::::::::: :::::::: ::... :::.:::::::::::
CCDS14 SLKDEMGNLRKLLESTPSPVVFCHNDIQEGNILLLSEPENADS--LMLVDFEYSSYNYRG
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE2 FDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSI
::::::::::.:::..:..::..: :::..:::::: :: .. :.:: ::.
CCDS14 FDIGNHFCEWVYDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKG-ETLSQEEQRK
280 290 300 310 320 330
410 420 430 440 450
pF1KE2 IKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
..:..:.::.:.::::::.::::::.::..:.:::::.::::.::. ::.:: .:
CCDS14 LEEDLLVEVSRYALASHFFWGLWSILQASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHS
340 350 360 370 380 390
CCDS14 SS
457 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:26:37 2016 done: Tue Nov 8 03:26:38 2016
Total Scan time: 3.740 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]