FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE9285, 246 aa
  1>>>pF1KE9285 246 - 246 aa - 246 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.2896+/-0.000322; mu= 1.6853+/- 0.020
 mean_var=189.9915+/-37.613, 0's: 0 Z-trim(121.6): 3  B-trim: 0 in 0/56
 Lambda= 0.093048
 statistics sampled from 38510 (38513) to 38510 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.452), width:  16
 Scan time:  6.290

The best scores are:                                      opt bits E(85289)
NP_056214 (OMIM: 606259) breast cancer metastasis- ( 246) 1618 228.7 7.3e-60
NP_001020128 (OMIM: 606259) breast cancer metastas ( 290) 1600 226.4 4.4e-59


>>NP_056214 (OMIM: 606259) breast cancer metastasis-supp  (246 aa)
 initn: 1618 init1: 1618 opt: 1618  Z-score: 1195.7  bits: 228.7 E(85289): 7.3e-60
Smith-Waterman score: 1618; 100.0% identity (100.0% similar) in 246 aa overlap (1-246:1-246)

               10        20        30        40        50        60
pF1KE9 MPVQPPSKDTEEMEAEGDSAAEMNGEEEESEEERSGSQTESEEESSEMDDEDYERRRSEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MPVQPPSKDTEEMEAEGDSAAEMNGEEEESEEERSGSQTESEEESSEMDDEDYERRRSEC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 VSEMLDLEKQFSELKEKLFRERLSQLRLRLEEVGAERAPEYTEPLGGLQRSLKIRIQVAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VSEMLDLEKQFSELKEKLFRERLSQLRLRLEEVGAERAPEYTEPLGGLQRSLKIRIQVAG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 IYKGFCLDVIRNKYECELQGAKQHLESEKLLLYDTLQGELQERIQRLEEDRQSLDLSSEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IYKGFCLDVIRNKYECELQGAKQHLESEKLLLYDTLQGELQERIQRLEEDRQSLDLSSEW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 WDDKLHARGSSRSWDSLPPSKRKKAPLVSGPYIVYMLQEIDILEDWTAIKKARAAVSPQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 WDDKLHARGSSRSWDSLPPSKRKKAPLVSGPYIVYMLQEIDILEDWTAIKKARAAVSPQK
              190       200       210       220       230       240

             
pF1KE9 RKSDGP
       ::::::
NP_056 RKSDGP
             

>>NP_001020128 (OMIM: 606259) breast cancer metastasis-s  (290 aa)
 initn: 1600 init1: 1600 opt: 1600  Z-score: 1181.7  bits: 226.4 E(85289): 4.4e-59
Smith-Waterman score: 1600; 100.0% identity (100.0% similar) in 244 aa overlap (1-244:1-244)

               10        20        30        40        50        60
pF1KE9 MPVQPPSKDTEEMEAEGDSAAEMNGEEEESEEERSGSQTESEEESSEMDDEDYERRRSEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPVQPPSKDTEEMEAEGDSAAEMNGEEEESEEERSGSQTESEEESSEMDDEDYERRRSEC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 VSEMLDLEKQFSELKEKLFRERLSQLRLRLEEVGAERAPEYTEPLGGLQRSLKIRIQVAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSEMLDLEKQFSELKEKLFRERLSQLRLRLEEVGAERAPEYTEPLGGLQRSLKIRIQVAG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 IYKGFCLDVIRNKYECELQGAKQHLESEKLLLYDTLQGELQERIQRLEEDRQSLDLSSEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IYKGFCLDVIRNKYECELQGAKQHLESEKLLLYDTLQGELQERIQRLEEDRQSLDLSSEW
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE9 WDDKLHARGSSRSWDSLPPSKRKKAPLVSGPYIVYMLQEIDILEDWTAIKKARAAVSPQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WDDKLHARGSSRSWDSLPPSKRKKAPLVSGPYIVYMLQEIDILEDWTAIKKARAAVSPQK
              190       200       210       220       230       240

                                                         
pF1KE9 RKSDGP                                            
       ::::                                              
NP_001 RKSDDRRTHRPLRVCPARLLWCCWALPLHLALAWTPPLPSSRPAQLWPWS
              250       260       270       280       290




246 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 10:20:19 2016 done: Tue Nov  8 10:20:20 2016
 Total Scan time:  6.290 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]