Result of FASTA (omim) for
pFN21AE5730
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5730, 630 aa
1>>>pF1KE5730 630 - 630 aa - 630 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1302+/-0.000374; mu= 20.1500+/- 0.023
mean_var=65.1239+/-12.717, 0's: 0 Z-trim(112.9): 82 B-trim: 40 in 1/55
Lambda= 0.158929
statistics sampled from 21863 (21957) to 21863 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.257), width: 16
Scan time: 8.900
The best scores are: opt bits E(85289)
NP_066265 (OMIM: 118490,254210) choline O-acetyltr ( 630) 4216 975.9 0
NP_066266 (OMIM: 118490,254210) choline O-acetyltr ( 630) 4216 975.9 0
NP_066264 (OMIM: 118490,254210) choline O-acetyltr ( 630) 4216 975.9 0
NP_001136401 (OMIM: 118490,254210) choline O-acety ( 630) 4216 975.9 0
NP_001136406 (OMIM: 118490,254210) choline O-acety ( 630) 4216 975.9 0
NP_001136405 (OMIM: 118490,254210) choline O-acety ( 666) 4216 975.9 0
NP_065574 (OMIM: 118490,254210) choline O-acetyltr ( 748) 4216 975.9 0
NP_003994 (OMIM: 600184) carnitine O-acetyltransfe ( 605) 1636 384.3 6.8e-106
NP_001244292 (OMIM: 600184) carnitine O-acetyltran ( 605) 1636 384.3 6.8e-106
NP_000746 (OMIM: 600184) carnitine O-acetyltransfe ( 626) 1636 384.3 6.9e-106
NP_001333475 (OMIM: 600184) carnitine O-acetyltran ( 627) 1636 384.3 7e-106
XP_005251765 (OMIM: 600184) PREDICTED: carnitine O ( 605) 1635 384.1 7.9e-106
XP_016869764 (OMIM: 600184) PREDICTED: carnitine O ( 627) 1635 384.1 8.2e-106
XP_016869763 (OMIM: 600184) PREDICTED: carnitine O ( 627) 1635 384.1 8.2e-106
NP_001333478 (OMIM: 600184) carnitine O-acetyltran ( 586) 1417 334.1 8.6e-91
NP_001333477 (OMIM: 600184) carnitine O-acetyltran ( 581) 1354 319.6 1.9e-86
NP_001333476 (OMIM: 600184) carnitine O-acetyltran ( 602) 1354 319.6 2e-86
NP_066974 (OMIM: 606090) peroxisomal carnitine O-o ( 612) 927 221.7 5.9e-57
XP_016872709 (OMIM: 255120,600528) PREDICTED: carn ( 773) 925 221.3 9.8e-57
NP_001867 (OMIM: 255120,600528) carnitine O-palmit ( 773) 925 221.3 9.8e-57
XP_005273819 (OMIM: 255120,600528) PREDICTED: carn ( 805) 925 221.3 1e-56
NP_001027017 (OMIM: 255120,600528) carnitine O-pal ( 756) 885 212.2 5.5e-54
XP_005273820 (OMIM: 255120,600528) PREDICTED: carn ( 788) 885 212.2 5.7e-54
XP_011514639 (OMIM: 606090) PREDICTED: peroxisomal ( 584) 882 211.4 7.2e-54
NP_001138609 (OMIM: 601987) carnitine O-palmitoylt ( 772) 882 211.5 9.1e-54
NP_689451 (OMIM: 601987) carnitine O-palmitoyltran ( 772) 882 211.5 9.1e-54
NP_001138607 (OMIM: 601987) carnitine O-palmitoylt ( 772) 882 211.5 9.1e-54
NP_689452 (OMIM: 601987) carnitine O-palmitoyltran ( 772) 882 211.5 9.1e-54
NP_004368 (OMIM: 601987) carnitine O-palmitoyltran ( 772) 882 211.5 9.1e-54
NP_001137407 (OMIM: 606090) peroxisomal carnitine ( 640) 853 204.8 7.8e-52
NP_001138606 (OMIM: 601987) carnitine O-palmitoylt ( 738) 823 197.9 1e-49
XP_016881759 (OMIM: 608846,616282) PREDICTED: carn ( 641) 799 192.4 4.2e-48
XP_016881757 (OMIM: 608846,616282) PREDICTED: carn ( 641) 799 192.4 4.2e-48
XP_016881758 (OMIM: 608846,616282) PREDICTED: carn ( 641) 799 192.4 4.2e-48
XP_016881756 (OMIM: 608846,616282) PREDICTED: carn ( 641) 799 192.4 4.2e-48
XP_011524740 (OMIM: 608846,616282) PREDICTED: carn ( 803) 799 192.5 5e-48
XP_005258562 (OMIM: 608846,616282) PREDICTED: carn ( 803) 799 192.5 5e-48
NP_001186682 (OMIM: 608846,616282) carnitine O-pal ( 803) 799 192.5 5e-48
XP_005258563 (OMIM: 608846,616282) PREDICTED: carn ( 803) 799 192.5 5e-48
NP_689572 (OMIM: 608846,616282) carnitine O-palmit ( 803) 799 192.5 5e-48
XP_011524741 (OMIM: 608846,616282) PREDICTED: carn ( 803) 799 192.5 5e-48
NP_001186681 (OMIM: 608846,616282) carnitine O-pal ( 803) 799 192.5 5e-48
XP_016881760 (OMIM: 608846,616282) PREDICTED: carn ( 630) 662 161.0 1.2e-38
NP_001129524 (OMIM: 608846,616282) carnitine O-pal ( 792) 662 161.0 1.4e-38
NP_000089 (OMIM: 255110,600649,600650,608836,61421 ( 658) 641 156.2 3.4e-37
XP_006723072 (OMIM: 608846,616282) PREDICTED: carn ( 674) 641 156.2 3.5e-37
XP_016881761 (OMIM: 608846,616282) PREDICTED: carn ( 596) 539 132.8 3.5e-30
XP_016881762 (OMIM: 608846,616282) PREDICTED: carn ( 596) 539 132.8 3.5e-30
XP_016881754 (OMIM: 608846,616282) PREDICTED: carn ( 758) 539 132.8 4.2e-30
XP_011524742 (OMIM: 608846,616282) PREDICTED: carn ( 758) 539 132.8 4.2e-30
>>NP_066265 (OMIM: 118490,254210) choline O-acetyltransf (630 aa)
initn: 4216 init1: 4216 opt: 4216 Z-score: 5219.0 bits: 975.9 E(85289): 0
Smith-Waterman score: 4216; 100.0% identity (100.0% similar) in 630 aa overlap (1-630:1-630)
10 20 30 40 50 60
pF1KE5 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 ISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 PEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 PEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 SEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 NRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 NRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 APRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 APRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 QVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDM
550 560 570 580 590 600
610 620 630
pF1KE5 RDLCSLLPPTESKPLATKEKATRPSQGHQP
::::::::::::::::::::::::::::::
NP_066 RDLCSLLPPTESKPLATKEKATRPSQGHQP
610 620 630
>>NP_066266 (OMIM: 118490,254210) choline O-acetyltransf (630 aa)
initn: 4216 init1: 4216 opt: 4216 Z-score: 5219.0 bits: 975.9 E(85289): 0
Smith-Waterman score: 4216; 100.0% identity (100.0% similar) in 630 aa overlap (1-630:1-630)
10 20 30 40 50 60
pF1KE5 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 ISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 PEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 PEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 SEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 NRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 NRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 APRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 APRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 QVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDM
550 560 570 580 590 600
610 620 630
pF1KE5 RDLCSLLPPTESKPLATKEKATRPSQGHQP
::::::::::::::::::::::::::::::
NP_066 RDLCSLLPPTESKPLATKEKATRPSQGHQP
610 620 630
>>NP_066264 (OMIM: 118490,254210) choline O-acetyltransf (630 aa)
initn: 4216 init1: 4216 opt: 4216 Z-score: 5219.0 bits: 975.9 E(85289): 0
Smith-Waterman score: 4216; 100.0% identity (100.0% similar) in 630 aa overlap (1-630:1-630)
10 20 30 40 50 60
pF1KE5 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 ISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 PEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 PEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 SEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 NRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 NRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 APRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 APRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 QVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDM
550 560 570 580 590 600
610 620 630
pF1KE5 RDLCSLLPPTESKPLATKEKATRPSQGHQP
::::::::::::::::::::::::::::::
NP_066 RDLCSLLPPTESKPLATKEKATRPSQGHQP
610 620 630
>>NP_001136401 (OMIM: 118490,254210) choline O-acetyltra (630 aa)
initn: 4216 init1: 4216 opt: 4216 Z-score: 5219.0 bits: 975.9 E(85289): 0
Smith-Waterman score: 4216; 100.0% identity (100.0% similar) in 630 aa overlap (1-630:1-630)
10 20 30 40 50 60
pF1KE5 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 PEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 SEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 NRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 APRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 QVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDM
550 560 570 580 590 600
610 620 630
pF1KE5 RDLCSLLPPTESKPLATKEKATRPSQGHQP
::::::::::::::::::::::::::::::
NP_001 RDLCSLLPPTESKPLATKEKATRPSQGHQP
610 620 630
>>NP_001136406 (OMIM: 118490,254210) choline O-acetyltra (630 aa)
initn: 4216 init1: 4216 opt: 4216 Z-score: 5219.0 bits: 975.9 E(85289): 0
Smith-Waterman score: 4216; 100.0% identity (100.0% similar) in 630 aa overlap (1-630:1-630)
10 20 30 40 50 60
pF1KE5 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 PEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEPEHVIVACCNQFFVLDVVINFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 SEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEWAEARTVLVKDSTNRDSLDMIERCICLVCLDAPGGVELSDTHRALQLLHGGGYSKNGA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 NRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADSVSELP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 APRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 LQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 LLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRFVLSTS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 QVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEESLIDM
550 560 570 580 590 600
610 620 630
pF1KE5 RDLCSLLPPTESKPLATKEKATRPSQGHQP
::::::::::::::::::::::::::::::
NP_001 RDLCSLLPPTESKPLATKEKATRPSQGHQP
610 620 630
>>NP_001136405 (OMIM: 118490,254210) choline O-acetyltra (666 aa)
initn: 4216 init1: 4216 opt: 4216 Z-score: 5218.6 bits: 975.9 E(85289): 0
Smith-Waterman score: 4216; 100.0% identity (100.0% similar) in 630 aa overlap (1-630:37-666)
10 20 30
pF1KE5 MAAKTPSSEESGLPKLPVPPLQQTLATYLQ
::::::::::::::::::::::::::::::
NP_001 DEALSTVGPHLCIPAPGLTKTPILEKVPRKMAAKTPSSEESGLPKLPVPPLQQTLATYLQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 CMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRL
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE5 ALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 CMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGD
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE5 LFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE5 CLDAPGGVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLDAPGGVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGI
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE5 VLVQCTEHLLKHMTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLVQCTEHLLKHMTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKN
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE5 LDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVD
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE5 NIRSATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NIRSATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALR
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE5 ELARAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELARAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPET
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE5 ILFCISSFHSCKETSSSKFAKAVEESLIDMRDLCSLLPPTESKPLATKEKATRPSQGHQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILFCISSFHSCKETSSSKFAKAVEESLIDMRDLCSLLPPTESKPLATKEKATRPSQGHQP
610 620 630 640 650 660
>>NP_065574 (OMIM: 118490,254210) choline O-acetyltransf (748 aa)
initn: 4216 init1: 4216 opt: 4216 Z-score: 5217.9 bits: 975.9 E(85289): 0
Smith-Waterman score: 4216; 100.0% identity (100.0% similar) in 630 aa overlap (1-630:119-748)
10 20 30
pF1KE5 MAAKTPSSEESGLPKLPVPPLQQTLATYLQ
::::::::::::::::::::::::::::::
NP_065 AAEPRRAGPHLCIPAPGLTKTPILEKVPRKMAAKTPSSEESGLPKLPVPPLQQTLATYLQ
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE5 CMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRL
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE5 ALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPL
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE5 CMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVVINFRRLSEGD
270 280 290 300 310 320
220 230 240 250 260 270
pF1KE5 LFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLV
330 340 350 360 370 380
280 290 300 310 320 330
pF1KE5 CLDAPGGVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CLDAPGGVELSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGI
390 400 410 420 430 440
340 350 360 370 380 390
pF1KE5 VLVQCTEHLLKHMTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VLVQCTEHLLKHMTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKN
450 460 470 480 490 500
400 410 420 430 440 450
pF1KE5 LDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVD
510 520 530 540 550 560
460 470 480 490 500 510
pF1KE5 NIRSATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 NIRSATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALR
570 580 590 600 610 620
520 530 540 550 560 570
pF1KE5 ELARAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ELARAMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPET
630 640 650 660 670 680
580 590 600 610 620 630
pF1KE5 ILFCISSFHSCKETSSSKFAKAVEESLIDMRDLCSLLPPTESKPLATKEKATRPSQGHQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ILFCISSFHSCKETSSSKFAKAVEESLIDMRDLCSLLPPTESKPLATKEKATRPSQGHQP
690 700 710 720 730 740
>>NP_003994 (OMIM: 600184) carnitine O-acetyltransferase (605 aa)
initn: 1187 init1: 426 opt: 1636 Z-score: 2022.2 bits: 384.3 E(85289): 6.8e-106
Smith-Waterman score: 1636; 42.6% identity (73.3% similar) in 611 aa overlap (2-608:3-601)
10 20 30 40 50
pF1KE5 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGE
:.. ......::.::::::::.: ::. .. .::::.. ... .:..: : ::.::
NP_003 MKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 TLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAAS
::. : .: .:: ::.::.::. ::. : . . :::.:.. .: : . ::::::.
NP_003 RLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 LISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSI
:: :::..:...:....:.. :.:.::::.::: ..:: :.:: ::: :.. :.
NP_003 LIEGVLDFKVMIDNETLPVE----YLGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKT
130 140 150 160 170
180 190 200 210 220 230
pF1KE5 MPEPEHVIVACCNQFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSD
: :. :. ::: ::: . :. ..:.::.:: . . . ... :.:.:::.
NP_003 KKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKE--PVGILTSN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 GRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDA--PGGVE-LSDTHRALQLLHGGGY
:. ::.: ..:.::..::::. :.. : ::::: : : . .: : :.:::::
NP_003 HRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE5 SKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADS
:..:::.::.:::.:..::.::.: ::. .: .: ...... . .:.:.
NP_003 RLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKP--ELVRSPM
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE5 VSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDA
: :: :..::.. .:::.. . .. ..:. ....::. :. : ..:: : :..: ::::
NP_003 VP-LPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDA
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE5 FIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPA
:::.:::::.::.. . ::::::.: :. ::.:.::::. ..:.::.:. : ..:
NP_003 FIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDD--SSVTE
420 430 440 450 460
480 490 500 510 520 530
pF1KE5 SEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRF
.:. ::. :..:. .:: :: : :.: :::.:. : .:..::: .: .. .:
NP_003 HQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHF
470 480 490 500 510 520
540 550 560 570 580 590
pF1KE5 VLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEE
:::::::. :. .:::::.:::.::::. : : .:...:: ::.....:. .:.
NP_003 HLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEK
530 540 550 560 570 580
600 610 620 630
pF1KE5 SLIDMRDLCSLLPPTESKPLATKEKATRPSQGHQP
.:.::: : . :
NP_003 ALLDMRALLQSHPRAKL
590 600
>>NP_001244292 (OMIM: 600184) carnitine O-acetyltransfer (605 aa)
initn: 1187 init1: 426 opt: 1636 Z-score: 2022.2 bits: 384.3 E(85289): 6.8e-106
Smith-Waterman score: 1636; 42.6% identity (73.3% similar) in 611 aa overlap (2-608:3-601)
10 20 30 40 50
pF1KE5 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGE
:.. ......::.::::::::.: ::. .. .::::.. ... .:..: : ::.::
NP_001 MKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 TLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAAS
::. : .: .:: ::.::.::. ::. : . . :::.:.. .: : . ::::::.
NP_001 RLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 LISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSI
:: :::..:...:....:.. :.:.::::.::: ..:: :.:: ::: :.. :.
NP_001 LIEGVLDFKVMIDNETLPVE----YLGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKT
130 140 150 160 170
180 190 200 210 220 230
pF1KE5 MPEPEHVIVACCNQFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSD
: :. :. ::: ::: . :. ..:.::.:: . . . ... :.:.:::.
NP_001 KKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKE--PVGILTSN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE5 GRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDA--PGGVE-LSDTHRALQLLHGGGY
:. ::.: ..:.::..::::. :.. : ::::: : : . .: : :.:::::
NP_001 HRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE5 SKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQSSRKLIRADS
:..:::.::.:::.:..::.::.: ::. .: .: ...... . .:.:.
NP_001 RLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKP--ELVRSPM
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE5 VSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDA
: :: :..::.. .:::.. . .. ..:. ....::. :. : ..:: : :..: ::::
NP_001 VP-LPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDA
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE5 FIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPA
:::.:::::.::.. . ::::::.: :. ::.:.::::. ..:.::.:. : ..:
NP_001 FIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDD--SSVTE
420 430 440 450 460
480 490 500 510 520 530
pF1KE5 SEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELARAMCKELPEMFMDETYLMSNRF
.:. ::. :..:. .:: :: : :.: :::.:. : .:..::: .: .. .:
NP_001 HQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHF
470 480 490 500 510 520
540 550 560 570 580 590
pF1KE5 VLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCKETSSSKFAKAVEE
:::::::. :. .:::::.:::.::::. : : .:...:: ::.....:. .:.
NP_001 HLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEK
530 540 550 560 570 580
600 610 620 630
pF1KE5 SLIDMRDLCSLLPPTESKPLATKEKATRPSQGHQP
.:.::: : . :
NP_001 ALLDMRALLQSHPRAKL
590 600
>>NP_000746 (OMIM: 600184) carnitine O-acetyltransferase (626 aa)
initn: 1187 init1: 426 opt: 1636 Z-score: 2022.0 bits: 384.3 E(85289): 6.9e-106
Smith-Waterman score: 1636; 42.6% identity (73.3% similar) in 611 aa overlap (2-608:24-622)
10 20 30
pF1KE5 MAAKTPSSEESGLPKLPVPPLQQTLATYLQCMRHLVSE
:.. ......::.::::::::.: ::. .. .:::
NP_000 MLAFAARTVVKPLGFLKPFSLMKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 EQFRKSQAIVQQFGAPGGLGETLQQKLLERQEKTANWVSEYWLNDMYLNNRLALPVNSSP
:.. ... .:..: : ::.:: ::. : .: .:: ::.::.::. ::. : . . :::
NP_000 EEWAHTKQLVDEFQASGGVGERLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSP
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE5 AVIFARQHFPGTDDQLRFAASLISGVLSYKALLDSHSIPTDCAKGQLSGQPLCMKQYYGL
.:.. .: : . ::::::.:: :::..:...:....:.. :.:.::::.::: .
NP_000 GVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMIDNETLPVE----YLGGKPLCMNQYYQI
130 140 150 160 170
160 170 180 190 200 210
pF1KE5 FSSYRLPGHTQDTLVAQNSSIMPEPEHVIVACCNQFFVLDVV-INFRRLSEGDLFTQLRK
.:: :.:: ::: :.. :. : :. :. ::: ::: . :. ..:.::.:
NP_000 LSSCRVPGPKQDT-VSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEK
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE5 IVKMASNEDERLPPIGLLTSDGRSEWAEARTVLVKDSTNRDSLDMIERCICLVCLDA--P
: . . . ... :.:.:::. :. ::.: ..:.::..::::. :.. : ::::: :
NP_000 IWNSSLQTNKE--PVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMP
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE5 GGVE-LSDTHRALQLLHGGGYSKNGANRWYDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQ
: . .: : :.::::: :..:::.::.:::.:..::.::.: ::. .: .:
NP_000 RVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVT
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE5 CTEHLLKHMTQSSRKLIRADSVSELPAPRRLRWKCSPEIQGHLASSAEKLQRIVKNLDFI
...... . .:.:. : :: :..::.. .:::.. . .. ..:. ....::.
NP_000 LLDYVIEYTKKP--ELVRSPMVP-LPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDIT
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE5 VYKFDNYGKTFIKKQKCSPDAFIQVALQLAFYRLHRRLVPTYESASIRRFQEGRVDNIRS
:. : ..:: : :..: :::::::.:::::.::.. . ::::::.: :. ::.:.:::
NP_000 VMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRS
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE5 ATPEALAFVRAVTDHKAAVPASEKLLLLKDAIRAQTAYTVMAITGMAIDNHLLALRELAR
:. ..:.::.:. : ..: .:. ::. :..:. .:: :: : :.: :::.:. :
NP_000 ASMDSLTFVKAMDD--SSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAI
480 490 500 510 520
520 530 540 550 560 570
pF1KE5 AMCKELPEMFMDETYLMSNRFVLSTSQVPTTTEMFCCYGPVVPNGYGACYNPQPETILFC
.:..::: .: .. .: :::::::. :. .:::::.:::.::::. : :
NP_000 EDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEAHINFS
530 540 550 560 570 580
580 590 600 610 620 630
pF1KE5 ISSFHSCKETSSSKFAKAVEESLIDMRDLCSLLPPTESKPLATKEKATRPSQGHQP
.:...:: ::.....:. .:..:.::: : . :
NP_000 LSAYNSCAETNAARLAHYLEKALLDMRALLQSHPRAKL
590 600 610 620
630 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 06:09:29 2016 done: Tue Nov 8 06:09:30 2016
Total Scan time: 8.900 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]