Result of FASTA (omim) for
pFN21AE5250
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5250, 194 aa
1>>>pF1KE5250 194 - 194 aa - 194 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6853+/-0.000341; mu= 16.0129+/- 0.021
mean_var=51.7257+/-10.251, 0's: 0 Z-trim(113.6): 19 B-trim: 0 in 0/53
Lambda= 0.178329
statistics sampled from 22950 (22969) to 22950 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.269), width: 16
Scan time: 4.920
The best scores are: opt bits E(85289)
NP_898881 (OMIM: 612748) lysozyme-like protein 2 [ ( 194) 1351 355.0 4.3e-98
XP_011517609 (OMIM: 612748) PREDICTED: lysozyme-li ( 163) 1002 265.2 4e-71
XP_011517608 (OMIM: 612748) PREDICTED: lysozyme-li ( 181) 1002 265.2 4.3e-71
NP_776246 (OMIM: 612749) sperm acrosome membrane-a ( 215) 532 144.3 1.3e-34
NP_995328 (OMIM: 300593) sperm acrosome-associated ( 159) 487 132.7 3e-31
XP_016885001 (OMIM: 300593) PREDICTED: sperm acros ( 159) 487 132.7 3e-31
NP_000230 (OMIM: 105200,153450) lysozyme C precurs ( 148) 485 132.2 4e-31
NP_001186880 (OMIM: 612751) lysozyme-like protein ( 148) 424 116.5 2.1e-26
NP_065159 (OMIM: 612751) lysozyme-like protein 6 p ( 148) 424 116.5 2.1e-26
NP_001291315 (OMIM: 612750) lysozyme-like protein ( 146) 395 109.0 3.7e-24
XP_016861194 (OMIM: 612750) PREDICTED: lysozyme-li ( 146) 395 109.0 3.7e-24
NP_653235 (OMIM: 612750) lysozyme-like protein 4 p ( 146) 395 109.0 3.7e-24
XP_016861195 (OMIM: 612750) PREDICTED: lysozyme-li ( 146) 395 109.0 3.7e-24
NP_001304155 (OMIM: 612749) sperm acrosome membran ( 112) 360 99.9 1.5e-21
NP_001304154 (OMIM: 612749) sperm acrosome membran ( 123) 360 100.0 1.6e-21
XP_011531657 (OMIM: 612750) PREDICTED: lysozyme-li ( 146) 329 92.0 4.8e-19
NP_002280 (OMIM: 149750) alpha-lactalbumin precurs ( 142) 323 90.5 1.4e-18
XP_006719458 (OMIM: 149750) PREDICTED: alpha-lacta ( 149) 323 90.5 1.4e-18
>>NP_898881 (OMIM: 612748) lysozyme-like protein 2 [Homo (194 aa)
initn: 1351 init1: 1351 opt: 1351 Z-score: 1882.1 bits: 355.0 E(85289): 4.3e-98
Smith-Waterman score: 1351; 100.0% identity (100.0% similar) in 194 aa overlap (1-194:1-194)
10 20 30 40 50 60
pF1KE5 MQDAPLSCLSPTKWSSVSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_898 MQDAPLSCLSPTKWSSVSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TGAESKIYTRCKLAKIFSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTVLDDGSIDYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_898 TGAESKIYTRCKLAKIFSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTVLDDGSIDYGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 FQINSFAWCRRGKLKENNHCHVACSALVTDDLTDAIICAKKIVKETQGMNYWQGWKKHCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_898 FQINSFAWCRRGKLKENNHCHVACSALVTDDLTDAIICAKKIVKETQGMNYWQGWKKHCE
130 140 150 160 170 180
190
pF1KE5 GRDLSDWKKDCEVS
::::::::::::::
NP_898 GRDLSDWKKDCEVS
190
>>XP_011517609 (OMIM: 612748) PREDICTED: lysozyme-like p (163 aa)
initn: 997 init1: 997 opt: 1002 Z-score: 1398.0 bits: 265.2 E(85289): 4e-71
Smith-Waterman score: 1002; 94.8% identity (96.8% similar) in 155 aa overlap (1-155:1-155)
10 20 30 40 50 60
pF1KE5 MQDAPLSCLSPTKWSSVSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQDAPLSCLSPTKWSSVSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TGAESKIYTRCKLAKIFSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTVLDDGSIDYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGAESKIYTRCKLAKIFSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTVLDDGSIDYGI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 FQINSFAWCRRGKLKENNHCHVACSALVTDDLTDAIICAKKIVKETQGMNYWQGWKKHCE
::::::::::::::::::::::::: .. :.:
XP_011 FQINSFAWCRRGKLKENNHCHVACSESWLENRTNANWVIGREY
130 140 150 160
190
pF1KE5 GRDLSDWKKDCEVS
>>XP_011517608 (OMIM: 612748) PREDICTED: lysozyme-like p (181 aa)
initn: 997 init1: 997 opt: 1002 Z-score: 1397.3 bits: 265.2 E(85289): 4.3e-71
Smith-Waterman score: 1002; 89.8% identity (94.0% similar) in 166 aa overlap (1-164:1-166)
10 20 30 40 50 60
pF1KE5 MQDAPLSCLSPTKWSSVSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQDAPLSCLSPTKWSSVSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TGAESKIYTRCKLAKIFSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTVLDDGSIDYGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGAESKIYTRCKLAKIFSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTVLDDGSIDYGI
70 80 90 100 110 120
130 140 150 160 170
pF1KE5 FQINSFAWCRRGKLKENNHCHVACSALVTDDLTDAIIC--AKKIVKETQGMNYWQGWKKH
:::::::::::::::::::::::::. . . . . : .:: :.
XP_011 FQINSFAWCRRGKLKENNHCHVACSGKAGRNTVRGETCPTGKKTVRFPKLELDPGCFAAT
130 140 150 160 170 180
180 190
pF1KE5 CEGRDLSDWKKDCEVS
XP_011 P
>>NP_776246 (OMIM: 612749) sperm acrosome membrane-assoc (215 aa)
initn: 526 init1: 488 opt: 532 Z-score: 742.7 bits: 144.3 E(85289): 1.3e-34
Smith-Waterman score: 532; 39.4% identity (70.2% similar) in 188 aa overlap (6-192:30-214)
10 20 30
pF1KE5 MQDAPLSCLSPTKWS-SVSSADSTEKSASAAGTRNL
.:::: . . : :.. :: .. : .: :
NP_776 MVSALRGAPLIRVHSSPVSSPSVSGPRRLVSCLSSQSSALSQSGGGSTSAAGIEARSRAL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE5 PFQFCLRQALRMKAAGILTLIGCLVTGAESKIYTRCKLAKIFSRAGLDNYWGFSLGNWIC
..: . . ... :..::. ..:.:.: ::.::... :::.: :.::..:.:
NP_776 RRRWCPAGIMLL---ALVCLLSCLLPSSEAKLYGRCELARVLHDFGLDGYRGYSLADWVC
70 80 90 100 110
100 110 120 130 140 150
pF1KE5 MAYYESGYNTTAQTVLDDGSIDYGIFQINSFAWCRRGKLKENNHCHVACSALVTDDLTDA
.::. ::.:..: ::: . ::::::: :: . : :.. :: :.. .: :.
NP_776 LAYFTSGFNAAALDYEADGSTNNGIFQINSRRWCSNLTPNVPNVCRMYCSDLLNPNLKDT
120 130 140 150 160 170
160 170 180 190
pF1KE5 IICAKKIVKETQGMNYWQGWKKHCEGRDLSDWKKDCEVS
.::: ::..: ::..::..:..::.:.::..: :.
NP_776 VICAMKITQEPQGLGYWEAWRHHCQGKDLTEWVDGCDF
180 190 200 210
>>NP_995328 (OMIM: 300593) sperm acrosome-associated pro (159 aa)
initn: 493 init1: 473 opt: 487 Z-score: 682.1 bits: 132.7 E(85289): 3e-31
Smith-Waterman score: 487; 45.0% identity (70.5% similar) in 149 aa overlap (47-193:1-149)
20 30 40 50 60 70
pF1KE5 VSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAG--ILTLIGCLVTGAESKIYTRCKLA
::: : ..:: .:. ...::: ::.::
NP_995 MKAWGTVVVTLATLMVVTVDAKIYERCELA
10 20 30
80 90 100 110 120 130
pF1KE5 KIFSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTVLDDGSIDYGIFQINSFAWCRRGKL
. ::::..: :...:.:.:::.::::..:. ::: .:::::.:: :: :
NP_995 ARLERAGLNGYKGYGVGDWLCMAHYESGFDTAFVDHNPDGSSEYGIFQLNSAWWCDNGIT
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE5 KENNHCHVACSALVTDDLTDAIICAKKIVKETQGMNYWQGWKKHCEGRDLSDWKKDCEVS
.: ::. : :.. . : : :::.::. .:.. : .:. :: :.:::.: : :..
NP_995 PTKNLCHMDCHDLLNRHILDDIRCAKQIVSSQNGLSAWTSWRLHCSGHDLSEWLKGCDMH
100 110 120 130 140 150
NP_995 VKIDPKIHP
>>XP_016885001 (OMIM: 300593) PREDICTED: sperm acrosome- (159 aa)
initn: 493 init1: 473 opt: 487 Z-score: 682.1 bits: 132.7 E(85289): 3e-31
Smith-Waterman score: 487; 45.0% identity (70.5% similar) in 149 aa overlap (47-193:1-149)
20 30 40 50 60 70
pF1KE5 VSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAG--ILTLIGCLVTGAESKIYTRCKLA
::: : ..:: .:. ...::: ::.::
XP_016 MKAWGTVVVTLATLMVVTVDAKIYERCELA
10 20 30
80 90 100 110 120 130
pF1KE5 KIFSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTVLDDGSIDYGIFQINSFAWCRRGKL
. ::::..: :...:.:.:::.::::..:. ::: .:::::.:: :: :
XP_016 ARLERAGLNGYKGYGVGDWLCMAHYESGFDTAFVDHNPDGSSEYGIFQLNSAWWCDNGIT
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE5 KENNHCHVACSALVTDDLTDAIICAKKIVKETQGMNYWQGWKKHCEGRDLSDWKKDCEVS
.: ::. : :.. . : : :::.::. .:.. : .:. :: :.:::.: : :..
XP_016 PTKNLCHMDCHDLLNRHILDDIRCAKQIVSSQNGLSAWTSWRLHCSGHDLSEWLKGCDMH
100 110 120 130 140 150
XP_016 VKIDPKIHP
>>NP_000230 (OMIM: 105200,153450) lysozyme C precursor [ (148 aa)
initn: 487 init1: 210 opt: 485 Z-score: 679.8 bits: 132.2 E(85289): 4e-31
Smith-Waterman score: 485; 45.6% identity (73.2% similar) in 149 aa overlap (47-193:1-148)
20 30 40 50 60 70
pF1KE5 VSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLVTGAESKIYTRCKLAKI
::: .: :. :: ...:.. ::.::.
NP_000 MKALIVLGLVLLSVT-VQGKVFERCELART
10 20
80 90 100 110 120 130
pF1KE5 FSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTV-LDDGSIDYGIFQINSFAWCRRGKLK
..: :.:.: :.::.::.:.: .:::::: : . : : ::::::::: :: ::
NP_000 LKRLGMDGYRGISLANWMCLAKWESGYNTRATNYNAGDRSTDYGIFQINSRYWCNDGKTP
30 40 50 60 70 80
140 150 160 170 180 190
pF1KE5 EN-NHCHVACSALVTDDLTDAIICAKKIVKETQGMNYWQGWKKHCEGRDLSDWKKDCEVS
: ::..::::. :...::. :::..:.. ::. : .:...:..::. .. . : :
NP_000 GAVNACHLSCSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQYVQGCGV
90 100 110 120 130 140
>>NP_001186880 (OMIM: 612751) lysozyme-like protein 6 pr (148 aa)
initn: 387 init1: 387 opt: 424 Z-score: 594.9 bits: 116.5 E(85289): 2.1e-26
Smith-Waterman score: 424; 38.8% identity (67.3% similar) in 147 aa overlap (47-193:1-147)
20 30 40 50 60 70
pF1KE5 VSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLVTGAESKIYTRCKLAKI
: : .. :.. ... .... .:: ::..
NP_001 MTKALLIYLVSSFLALNQASLISRCDLAQV
10 20 30
80 90 100 110 120 130
pF1KE5 FSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTVLDDGSIDYGIFQINSFAWCRRGKLKE
.. ::.. :.::..:.:.:. :: .: . . :::.:::.::::: :: :
NP_001 LQLEDLDGFEGYSLSDWLCLAFVESKFNISKINENADGSFDYGLFQINSHYWCNDYKSYS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE5 NNHCHVACSALVTDDLTDAIICAKKIVKETQGMNYWQGWKKHCEGRDLSDWKKDCEVS
.: ::: :. :.. .: .: :::.::. ..::: : :. :: :: : : :..
NP_001 ENLCHVDCQDLLNPNLLAGIHCAKRIVSGARGMNNWVEWRLHCSGRPLFYWLTGCRLR
100 110 120 130 140
>>NP_065159 (OMIM: 612751) lysozyme-like protein 6 precu (148 aa)
initn: 387 init1: 387 opt: 424 Z-score: 594.9 bits: 116.5 E(85289): 2.1e-26
Smith-Waterman score: 424; 38.8% identity (67.3% similar) in 147 aa overlap (47-193:1-147)
20 30 40 50 60 70
pF1KE5 VSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLVTGAESKIYTRCKLAKI
: : .. :.. ... .... .:: ::..
NP_065 MTKALLIYLVSSFLALNQASLISRCDLAQV
10 20 30
80 90 100 110 120 130
pF1KE5 FSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTVLDDGSIDYGIFQINSFAWCRRGKLKE
.. ::.. :.::..:.:.:. :: .: . . :::.:::.::::: :: :
NP_065 LQLEDLDGFEGYSLSDWLCLAFVESKFNISKINENADGSFDYGLFQINSHYWCNDYKSYS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE5 NNHCHVACSALVTDDLTDAIICAKKIVKETQGMNYWQGWKKHCEGRDLSDWKKDCEVS
.: ::: :. :.. .: .: :::.::. ..::: : :. :: :: : : :..
NP_065 ENLCHVDCQDLLNPNLLAGIHCAKRIVSGARGMNNWVEWRLHCSGRPLFYWLTGCRLR
100 110 120 130 140
>>NP_001291315 (OMIM: 612750) lysozyme-like protein 4 pr (146 aa)
initn: 384 init1: 192 opt: 395 Z-score: 554.7 bits: 109.0 E(85289): 3.7e-24
Smith-Waterman score: 395; 39.3% identity (65.3% similar) in 150 aa overlap (47-193:1-146)
20 30 40 50 60 70
pF1KE5 VSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLVTGAESKIYTRCKLAKI
:::. .:.:.: ::. . . : :: .::
NP_001 MKASVVLSLLGYLVVPSGAYILGRCTVAKK
10 20 30
80 90 100 110 120 130
pF1KE5 FSRAGLDNYWGFSLGNWICMAYYESGYNTTA-QTVLDDGSIDYGIFQINSFAWC-RRGKL
. .::: . :.:: ::.:.::.:: .: : .: .:.::. . :: .:.
NP_001 LHDGGLDYFEGYSLENWVCLAYFESKFNPMAIYENTREGYTGFGLFQMRGSDWCGDHGR-
40 50 60 70 80
140 150 160 170 180 190
pF1KE5 KENNHCHVACSALVTDDLTDAIICAKKIVKETQGMNYWQGWKKHCEGRD-LSDWKKDCEV
:.::..::::.. .: .: ::: ::: .::. : :...:. : :. : :..
NP_001 ---NRCHMSCSALLNPNLEKTIKCAKTIVKGKEGMGAWPTWSRYCQYSDTLARWLDGCKL
90 100 110 120 130 140
pF1KE5 S
194 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 07:23:50 2016 done: Tue Nov 8 07:23:51 2016
Total Scan time: 4.920 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]