Result of FASTA (omim) for
pFN21AE5320
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5320, 291 aa
1>>>pF1KE5320 291 - 291 aa - 291 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6432+/-0.000394; mu= 18.4501+/- 0.024
mean_var=55.7714+/-11.134, 0's: 0 Z-trim(111.8): 18 B-trim: 89 in 1/51
Lambda= 0.171739
statistics sampled from 20459 (20474) to 20459 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.24), width: 16
Scan time: 5.160
The best scores are: opt bits E(85289)
NP_060582 (OMIM: 611236,615066) trimeric intracell ( 291) 1975 497.5 1.2e-140
XP_005252132 (OMIM: 611236,615066) PREDICTED: trim ( 237) 1603 405.3 5.9e-113
XP_005252134 (OMIM: 611236,615066) PREDICTED: trim ( 220) 1504 380.7 1.3e-105
XP_005252133 (OMIM: 611236,615066) PREDICTED: trim ( 225) 1504 380.7 1.4e-105
XP_011517131 (OMIM: 611236,615066) PREDICTED: trim ( 215) 1260 320.3 2.1e-87
XP_011517133 (OMIM: 611236,615066) PREDICTED: trim ( 215) 1260 320.3 2.1e-87
XP_011517135 (OMIM: 611236,615066) PREDICTED: trim ( 175) 1173 298.6 5.5e-81
NP_076979 (OMIM: 611235) trimeric intracellular ca ( 299) 836 215.3 1.1e-55
XP_011517134 (OMIM: 611236,615066) PREDICTED: trim ( 200) 715 185.2 8.8e-47
>>NP_060582 (OMIM: 611236,615066) trimeric intracellular (291 aa)
initn: 1975 init1: 1975 opt: 1975 Z-score: 2645.8 bits: 497.5 E(85289): 1.2e-140
Smith-Waterman score: 1975; 100.0% identity (100.0% similar) in 291 aa overlap (1-291:1-291)
10 20 30 40 50 60
pF1KE5 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 YPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 YPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTL
190 200 210 220 230 240
250 260 270 280 290
pF1KE5 SWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVKKKHTKKNE
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVKKKHTKKNE
250 260 270 280 290
>>XP_005252132 (OMIM: 611236,615066) PREDICTED: trimeric (237 aa)
initn: 1603 init1: 1603 opt: 1603 Z-score: 2148.9 bits: 405.3 E(85289): 5.9e-113
Smith-Waterman score: 1603; 100.0% identity (100.0% similar) in 237 aa overlap (55-291:1-237)
30 40 50 60 70 80
pF1KE5 HYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFGGGILSCLLLAEPPLKFLANHTNIL
::::::::::::::::::::::::::::::
XP_005 MLHCFGGGILSCLLLAEPPLKFLANHTNIL
10 20 30
90 100 110 120 130 140
pF1KE5 LASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEVTRTWKIVGGVTHANSYYKNGWIVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEVTRTWKIVGGVTHANSYYKNGWIVM
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE5 IAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMSYPAKVTLLGSVIFTFQHTQHLAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMSYPAKVTLLGSVIFTFQHTQHLAIS
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE5 KHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKSPS
160 170 180 190 200 210
270 280 290
pF1KE5 NGVGSLASKPVDVASDNVKKKHTKKNE
:::::::::::::::::::::::::::
XP_005 NGVGSLASKPVDVASDNVKKKHTKKNE
220 230
>>XP_005252134 (OMIM: 611236,615066) PREDICTED: trimeric (220 aa)
initn: 1504 init1: 1504 opt: 1504 Z-score: 2016.8 bits: 380.7 E(85289): 1.3e-105
Smith-Waterman score: 1504; 100.0% identity (100.0% similar) in 220 aa overlap (1-220:1-220)
10 20 30 40 50 60
pF1KE5 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 YPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTL
::::::::::::::::::::::::::::::::::::::::
XP_005 YPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATK
190 200 210 220
250 260 270 280 290
pF1KE5 SWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVKKKHTKKNE
>>XP_005252133 (OMIM: 611236,615066) PREDICTED: trimeric (225 aa)
initn: 1504 init1: 1504 opt: 1504 Z-score: 2016.7 bits: 380.7 E(85289): 1.4e-105
Smith-Waterman score: 1504; 100.0% identity (100.0% similar) in 220 aa overlap (1-220:1-220)
10 20 30 40 50 60
pF1KE5 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 YPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTL
::::::::::::::::::::::::::::::::::::::::
XP_005 YPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKSLNWR
190 200 210 220
250 260 270 280 290
pF1KE5 SWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVKKKHTKKNE
>>XP_011517131 (OMIM: 611236,615066) PREDICTED: trimeric (215 aa)
initn: 1260 init1: 1260 opt: 1260 Z-score: 1690.2 bits: 320.3 E(85289): 2.1e-87
Smith-Waterman score: 1260; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181)
10 20 30 40 50 60
pF1KE5 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 YPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTL
:
XP_011 YFRVHVQNVQPCQGNPAGVSYLHIPAHPASGNIKA
190 200 210
>>XP_011517133 (OMIM: 611236,615066) PREDICTED: trimeric (215 aa)
initn: 1260 init1: 1260 opt: 1260 Z-score: 1690.2 bits: 320.3 E(85289): 2.1e-87
Smith-Waterman score: 1260; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181)
10 20 30 40 50 60
pF1KE5 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 TRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 YPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTL
:
XP_011 YFRVHVQNVQPCQGNPAGVSYLHIPAHPASGNIKA
190 200 210
>>XP_011517135 (OMIM: 611236,615066) PREDICTED: trimeric (175 aa)
initn: 1173 init1: 1173 opt: 1173 Z-score: 1575.0 bits: 298.6 E(85289): 5.5e-81
Smith-Waterman score: 1173; 100.0% identity (100.0% similar) in 175 aa overlap (117-291:1-175)
90 100 110 120 130 140
pF1KE5 SSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEVTRTWKIVGGVTHANSYYKNGWIVMIA
::::::::::::::::::::::::::::::
XP_011 MKEVTRTWKIVGGVTHANSYYKNGWIVMIA
10 20 30
150 160 170 180 190 200
pF1KE5 IGWARGAGGTIITNFERLVKGDWKPEGDEWLKMSYPAKVTLLGSVIFTFQHTQHLAISKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGWARGAGGTIITNFERLVKGDWKPEGDEWLKMSYPAKVTLLGSVIFTFQHTQHLAISKH
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE5 NLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKSPSNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKSPSNG
100 110 120 130 140 150
270 280 290
pF1KE5 VGSLASKPVDVASDNVKKKHTKKNE
:::::::::::::::::::::::::
XP_011 VGSLASKPVDVASDNVKKKHTKKNE
160 170
>>NP_076979 (OMIM: 611235) trimeric intracellular cation (299 aa)
initn: 829 init1: 829 opt: 836 Z-score: 1120.4 bits: 215.3 E(85289): 1.1e-55
Smith-Waterman score: 836; 41.2% identity (76.2% similar) in 294 aa overlap (7-291:11-299)
10 20 30 40 50
pF1KE5 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAML
::::.:::. .:: ::.....::.. .: .:::. :. ..::.::. :::
NP_076 MELLSALSLGELALSFSRVPLFPVFDLSYFIVSILYLKYEPGAVELSRRHPIASWLCAML
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 HCFGGGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASG
::::. ::. :::.:: . ...:...:::::..::. :::: :: . .:::.:. .
NP_076 HCFGSYILADLLLGEPLIDYFSNNSSILLASAVWYLIFFCPLDLFYKCVCFLPVKLIFVA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 MKEVTRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEW
::::.:. ::. :. ::. .:..::.:::: ::..:.: ....:::.:..: :::: .:
NP_076 MKEVVRVRKIAVGIHHAHHHYHHGWFVMIATGWVKGSGVALMSNFEQLLRGVWKPETNEI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 LKMSYPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKITMMTTQTSTMTFAPF
:.::.:.:..: :...::.:.:. : .:: .:.:..:.:.:. :. . .:.. . : .
NP_076 LHMSFPTKASLYGAILFTLQQTRWLPVSKASLIFIFTLFMVSCKVFLTATHSHSSPFDAL
190 200 210 220 230 240
240 250 260 270 280
pF1KE5 EDTLSWMLFGWQQPFSSC--EKKSEAKSPSNGVG-------SLASKPVDVASDNVKKKHT
: . .::: :.: ... . .. :.. : .. .: . :.. .::..
NP_076 EGYICPVLFG-----SACGGDHHHDNHGGSHSGGGPGAQHSAMPAKSKEELSEGSRKKKA
250 260 270 280 290
290
pF1KE5 KKNE
:: .
NP_076 KKAD
>>XP_011517134 (OMIM: 611236,615066) PREDICTED: trimeric (200 aa)
initn: 1307 init1: 715 opt: 715 Z-score: 960.9 bits: 185.2 E(85289): 8.8e-47
Smith-Waterman score: 1132; 68.7% identity (68.7% similar) in 291 aa overlap (1-291:1-200)
10 20 30 40 50 60
pF1KE5 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDSPWDELALAFSRTSMFPFFDIAHYLVSVMAVKRQPGAAALAWKNPISSWFTAMLHCFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 GGILSCLLLAEPPLKFLANHTNILLASSIWYITFFCPHDLVSQGYSYLPVQLLASGMKEV
::::::::::::::::::::::::::::: ::
XP_011 GGILSCLLLAEPPLKFLANHTNILLASSI------CP-----------------------
70 80 90
130 140 150 160 170 180
pF1KE5 TRTWKIVGGVTHANSYYKNGWIVMIAIGWARGAGGTIITNFERLVKGDWKPEGDEWLKMS
XP_011 ------------------------------------------------------------
190 200 210 220 230 240
pF1KE5 YPAKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 --AKVTLLGSVIFTFQHTQHLAISKHNLMFLYTIFIVATKITMMTTQTSTMTFAPFEDTL
100 110 120 130 140
250 260 270 280 290
pF1KE5 SWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVKKKHTKKNE
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVKKKHTKKNE
150 160 170 180 190 200
291 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 07:31:48 2016 done: Tue Nov 8 07:31:48 2016
Total Scan time: 5.160 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]