Result of FASTA (omim) for
pFN21AE6635
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6635, 247 aa
1>>>pF1KE6635 247 - 247 aa - 247 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9267+/-0.000361; mu= 16.2317+/- 0.022
mean_var=62.7570+/-12.696, 0's: 0 Z-trim(112.5): 11 B-trim: 104 in 1/50
Lambda= 0.161899
statistics sampled from 21424 (21435) to 21424 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.251), width: 16
Scan time: 3.830
The best scores are: opt bits E(85289)
NP_056284 (OMIM: 608871) protein NipSnap homolog 3 ( 247) 1677 400.3 1.6e-111
NP_060846 (OMIM: 608872) protein NipSnap homolog 3 ( 247) 1492 357.1 1.7e-98
XP_016870378 (OMIM: 608872) PREDICTED: protein Nip ( 231) 1353 324.6 9.4e-89
NP_001316499 (OMIM: 608871) protein NipSnap homolo ( 197) 973 235.8 4.4e-62
XP_011517141 (OMIM: 608872) PREDICTED: protein Nip ( 197) 823 200.8 1.5e-51
NP_001474 (OMIM: 603004) protein NipSnap homolog 2 ( 286) 244 65.6 1.1e-10
NP_001189431 (OMIM: 603249) protein NipSnap homolo ( 264) 233 63.0 5.9e-10
NP_003625 (OMIM: 603249) protein NipSnap homolog 1 ( 284) 233 63.1 6.3e-10
NP_001189398 (OMIM: 603004) protein NipSnap homolo ( 247) 164 46.9 4e-05
>>NP_056284 (OMIM: 608871) protein NipSnap homolog 3A is (247 aa)
initn: 1677 init1: 1677 opt: 1677 Z-score: 2122.9 bits: 400.3 E(85289): 1.6e-111
Smith-Waterman score: 1677; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247)
10 20 30 40 50 60
pF1KE6 MLVLRSALTRALASRTLAPQMCSSFATGPRQYDGIFYEFRSYYLKPSKMNEFLENFEKNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MLVLRSALTRALASRTLAPQMCSSFATGPRQYDGIFYEFRSYYLKPSKMNEFLENFEKNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 HLRTAHSELVGYWSVEFGGRMNTVFHIWKYDNFAHRTEVRKALAKDKEWQEQFLIPNLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HLRTAHSELVGYWSVEFGGRMNTVFHIWKYDNFAHRTEVRKALAKDKEWQEQFLIPNLAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IDKQESEITYLVPWCKLEKPPKEGVYELATFQMKPGGPALWGDAFKRAVHAHVNLGYTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IDKQESEITYLVPWCKLEKPPKEGVYELATFQMKPGGPALWGDAFKRAVHAHVNLGYTKL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VGVFHTEYGALNRVHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VGVFHTEYGALNRVHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIP
190 200 210 220 230 240
pF1KE6 TSFSPLK
:::::::
NP_056 TSFSPLK
>>NP_060846 (OMIM: 608872) protein NipSnap homolog 3B [H (247 aa)
initn: 1492 init1: 1492 opt: 1492 Z-score: 1889.4 bits: 357.1 E(85289): 1.7e-98
Smith-Waterman score: 1492; 87.0% identity (96.0% similar) in 247 aa overlap (1-247:1-247)
10 20 30 40 50 60
pF1KE6 MLVLRSALTRALASRTLAPQMCSSFATGPRQYDGIFYEFRSYYLKPSKMNEFLENFEKNA
::::::.::.::::::::::.::::::::::::: :::::.::::::.:: :.::..::
NP_060 MLVLRSGLTKALASRTLAPQVCSSFATGPRQYDGTFYEFRTYYLKPSNMNAFMENLKKNI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 HLRTAHSELVGYWSVEFGGRMNTVFHIWKYDNFAHRTEVRKALAKDKEWQEQFLIPNLAL
::::..:::::.:::::::: : :::::::::::::.:::::::. :::::: .:::::
NP_060 HLRTSYSELVGFWSVEFGGRTNKVFHIWKYDNFAHRAEVRKALANCKEWQEQSIIPNLAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IDKQESEITYLVPWCKLEKPPKEGVYELATFQMKPGGPALWGDAFKRAVHAHVNLGYTKL
:::::.:::::.:: ::::::::::::::.:::::::::::::::.::..:::::::::.
NP_060 IDKQETEITYLIPWSKLEKPPKEGVYELAVFQMKPGGPALWGDAFERAINAHVNLGYTKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VGVFHTEYGALNRVHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIP
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VGVFHTEYGELNRVHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIP
190 200 210 220 230 240
pF1KE6 TSFSPLK
.::::::
NP_060 ASFSPLK
>>XP_016870378 (OMIM: 608872) PREDICTED: protein NipSnap (231 aa)
initn: 1396 init1: 1353 opt: 1353 Z-score: 1714.3 bits: 324.6 E(85289): 9.4e-89
Smith-Waterman score: 1353; 85.4% identity (95.1% similar) in 226 aa overlap (1-226:1-226)
10 20 30 40 50 60
pF1KE6 MLVLRSALTRALASRTLAPQMCSSFATGPRQYDGIFYEFRSYYLKPSKMNEFLENFEKNA
::::::.::.::::::::::.::::::::::::: :::::.::::::.:: :.::..::
XP_016 MLVLRSGLTKALASRTLAPQVCSSFATGPRQYDGTFYEFRTYYLKPSNMNAFMENLKKNI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 HLRTAHSELVGYWSVEFGGRMNTVFHIWKYDNFAHRTEVRKALAKDKEWQEQFLIPNLAL
::::..:::::.:::::::: : :::::::::::::.:::::::. :::::: .:::::
XP_016 HLRTSYSELVGFWSVEFGGRTNKVFHIWKYDNFAHRAEVRKALANCKEWQEQSIIPNLAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IDKQESEITYLVPWCKLEKPPKEGVYELATFQMKPGGPALWGDAFKRAVHAHVNLGYTKL
:::::.:::::.:: ::::::::::::::.:::::::::::::::.::..:::::::::.
XP_016 IDKQETEITYLIPWSKLEKPPKEGVYELAVFQMKPGGPALWGDAFERAINAHVNLGYTKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VGVFHTEYGALNRVHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIP
::::::::: :::::::::::::::::::::::::::::::: ::.
XP_016 VGVFHTEYGELNRVHVLWWNESADSRAAGRHKSHEDPRVVAAGRETDMQPI
190 200 210 220 230
pF1KE6 TSFSPLK
>>NP_001316499 (OMIM: 608871) protein NipSnap homolog 3A (197 aa)
initn: 1319 init1: 973 opt: 973 Z-score: 1235.7 bits: 235.8 E(85289): 4.4e-62
Smith-Waterman score: 1223; 79.8% identity (79.8% similar) in 247 aa overlap (1-247:1-197)
10 20 30 40 50 60
pF1KE6 MLVLRSALTRALASRTLAPQMCSSFATGPRQYDGIFYEFRSYYLKPSKMNEFLENFEKNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLVLRSALTRALASRTLAPQMCSSFATGPRQYDGIFYEFRSYYLKPSKMNEFLENFEKNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 HLRTAHSELVGYWSVEFGGRMNTVFHIWKYDNFAHRTEVRKALAKDKEWQEQFLIPNLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLRTAHSELVGYWSVEFGGRMNTVFHIWKYDNFAHRTEVRKALAKDKEWQEQFLIPNLAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IDKQESEITYLVPWCKLEKPPKEGVYELATFQMKPGGPALWGDAFKRAVHAHVNLGYTKL
:::::::::::::::::::::::
NP_001 IDKQESEITYLVPWCKLEKPPKE-------------------------------------
130 140
190 200 210 220 230 240
pF1KE6 VGVFHTEYGALNRVHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIP
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------------VHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIP
150 160 170 180 190
pF1KE6 TSFSPLK
:::::::
NP_001 TSFSPLK
>>XP_011517141 (OMIM: 608872) PREDICTED: protein NipSnap (197 aa)
initn: 1164 init1: 823 opt: 823 Z-score: 1046.3 bits: 200.8 E(85289): 1.5e-51
Smith-Waterman score: 1068; 69.2% identity (76.1% similar) in 247 aa overlap (1-247:1-197)
10 20 30 40 50 60
pF1KE6 MLVLRSALTRALASRTLAPQMCSSFATGPRQYDGIFYEFRSYYLKPSKMNEFLENFEKNA
::::::.::.::::::::::.::::::::::::: :::::.::::::.:: :.::..::
XP_011 MLVLRSGLTKALASRTLAPQVCSSFATGPRQYDGTFYEFRTYYLKPSNMNAFMENLKKNI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 HLRTAHSELVGYWSVEFGGRMNTVFHIWKYDNFAHRTEVRKALAKDKEWQEQFLIPNLAL
::::..:::::.:::::::: : :::::::::::::.:::::::. :::::: .:::::
XP_011 HLRTSYSELVGFWSVEFGGRTNKVFHIWKYDNFAHRAEVRKALANCKEWQEQSIIPNLAR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 IDKQESEITYLVPWCKLEKPPKEGVYELATFQMKPGGPALWGDAFKRAVHAHVNLGYTKL
:::::.:::::.:: ::::::::
XP_011 IDKQETEITYLIPWSKLEKPPKE-------------------------------------
130 140
190 200 210 220 230 240
pF1KE6 VGVFHTEYGALNRVHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIP
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -------------VHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIP
150 160 170 180 190
pF1KE6 TSFSPLK
.::::::
XP_011 ASFSPLK
>>NP_001474 (OMIM: 603004) protein NipSnap homolog 2 iso (286 aa)
initn: 204 init1: 131 opt: 244 Z-score: 313.1 bits: 65.6 E(85289): 1.1e-10
Smith-Waterman score: 244; 24.5% identity (54.6% similar) in 249 aa overlap (10-247:47-286)
10 20 30
pF1KE6 MLVLRSALTRALASRTLAPQMCSSFATGPRQYDGIFYEF
..: : . :. . .. . .:..
NP_001 LLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKL
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 RSYYLKPSKMNEFLENFEKNAH--LRTAHSE------LVGYWSVEFGGRMNTVFHIWKYD
. . .:: : :: ..: . : : . ::: :.. .: ... . :.:.:.
NP_001 QFHNVKP----ECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYG-EQDQAVHLWRYE
80 90 100 110 120 130
100 110 120 130 140
pF1KE6 N-FAHRTEVRKALAKDKEWQEQFLIPNLALIDKQESEITYLVPWCKLEKPPKEG--VYEL
. . ::: . : ..::. : . :...... . . : : :. : .:::
NP_001 GGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWN--EPVPRSGPNIYEL
140 150 160 170 180
150 160 170 180 190 200
pF1KE6 ATFQMKPGGPALWGDAFKRAVHAHVNLGYTKLVGVFHTEYGALNRVHVLWWNESADSRAA
..:..:: ::. . ::.. . . : .. :: : .. : : :: :: .. ..:
NP_001 RSYQLRPGTMIEWGNYWARAIRFRQD-G-NEAVGGFFSQIGQLYMVHHLWAYRDLQTRED
190 200 210 220 230 240
210 220 230 240
pF1KE6 GRHKSHEDPRVVAAVRESVNYLVSQQNMLLIPTSFSPLK
:. . . : .: . ... ..:: . :::.
NP_001 IRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
250 260 270 280
>>NP_001189431 (OMIM: 603249) protein NipSnap homolog 1 (264 aa)
initn: 192 init1: 93 opt: 233 Z-score: 299.7 bits: 63.0 E(85289): 5.9e-10
Smith-Waterman score: 233; 22.9% identity (53.9% similar) in 245 aa overlap (10-247:25-264)
10 20 30 40
pF1KE6 MLVLRSALTRALASRTLAPQMCSSFATGPRQYDGIFYEFRSYYLK
:.: . . :. . . .. . .:... . .:
NP_001 MAPRLCSISVTARFYSKDNEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 PSKM---NEFLENFEKNAHLRTAHS-ELVGYWSVEFGGRMNTVFHIWKYDN-FAHRTEVR
: . : . : . :: . ::: :.. .: ... . :.:.... . .
NP_001 PEYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYG-EQDQAVHLWRFSGGYPALMDCM
70 80 90 100 110
110 120 130 140 150
pF1KE6 KALAKDKEWQEQFLIPNLALIDKQESEITYLVPWCKLEKPPKEG--VYELATFQMKPGGP
. : ..::. : . :...... . . : : :. : .::: :...:::
NP_001 NKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWN--EPQPRMGPNIYELRTYKLKPGTM
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE6 ALWGDAFKRAVHAHVNLGYTKLVGVFHTEYGALNRVHVLWWNESADSRAAGRHKSHEDPR
::. . ::.. . . . :: : .. : : :: :: .. .:: :. . .
NP_001 IEWGNNWARAIKYRQE--NQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRG
180 190 200 210 220 230
220 230 240
pF1KE6 VVAAVRESVNYLVSQQNMLLIPTSFSPLK
: .: . ... ..:: ..:::.
NP_001 WDENVYYTVPLVRHMESRIMIPLKISPLQ
240 250 260
>>NP_003625 (OMIM: 603249) protein NipSnap homolog 1 iso (284 aa)
initn: 192 init1: 93 opt: 233 Z-score: 299.3 bits: 63.1 E(85289): 6.3e-10
Smith-Waterman score: 233; 22.9% identity (53.9% similar) in 245 aa overlap (10-247:45-284)
10 20 30
pF1KE6 MLVLRSALTRALASRTLAPQMCSSFATGPRQYDGIFYEF
:.: . . :. . . .. . .:..
NP_003 LLGGPGPRAGDVASAAAARFYSKDNEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKI
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 RSYYLKPSKM---NEFLENFEKNAHLRTAHS-ELVGYWSVEFGGRMNTVFHIWKYDN-FA
. . .:: . : . : . :: . ::: :.. .: ... . :.:.... .
NP_003 QFHNVKPEYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYG-EQDQAVHLWRFSGGYP
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 HRTEVRKALAKDKEWQEQFLIPNLALIDKQESEITYLVPWCKLEKPPKEG--VYELATFQ
. . : ..::. : . :...... . . : : :. : .::: :..
NP_003 ALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWN--EPQPRMGPNIYELRTYK
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE6 MKPGGPALWGDAFKRAVHAHVNLGYTKLVGVFHTEYGALNRVHVLWWNESADSRAAGRHK
.::: ::. . ::.. . . . :: : .. : : :: :: .. .:: :.
NP_003 LKPGTMIEWGNNWARAIKYRQE--NQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNA
200 210 220 230 240
220 230 240
pF1KE6 SHEDPRVVAAVRESVNYLVSQQNMLLIPTSFSPLK
. . : .: . ... ..:: ..:::.
NP_003 AWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ
250 260 270 280
>>NP_001189398 (OMIM: 603004) protein NipSnap homolog 2 (247 aa)
initn: 161 init1: 88 opt: 164 Z-score: 213.0 bits: 46.9 E(85289): 4e-05
Smith-Waterman score: 176; 29.6% identity (58.5% similar) in 135 aa overlap (2-133:112-240)
10 20 30
pF1KE6 MLVLRSALTRALASRTLAPQMCSSFATGPRQ
: .:.: . : :: . :: . :
NP_001 CQRFTKINTTLVLWWGLGTRGMASRTKLEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE6 YDGI-FYEFRSYYLKPSKMNEFLENFEKNAHLRTAHSELVGYWSVEFGGRMNTVFHIWKY
.: .::.::: :.:. : :. . . . ..: .: :: . ..: .. : :.: :
NP_001 RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIG-QLYMVHHLWAY
150 160 170 180 190 200
100 110 120 130 140
pF1KE6 DNFAHRTEVRKALAKDKEWQE--QFLIPNLALIDKQESEITYLVPWCKLEKPPKEGVYEL
.. : ..:.: . . :.: . .: ::...::.: ..:
NP_001 RDLQTREDIRNAAWHKHGWEELVYYTVP---LIQEMESRI--MIPLKTSPLQ
210 220 230 240
150 160 170 180 190 200
pF1KE6 ATFQMKPGGPALWGDAFKRAVHAHVNLGYTKLVGVFHTEYGALNRVHVLWWNESADSRAA
247 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:58:42 2016 done: Tue Nov 8 14:58:42 2016
Total Scan time: 3.830 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]