Result of FASTA (omim) for
pFN21AE3413
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3413, 346 aa
1>>>pF1KE3413 346 - 346 aa - 346 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.3625+/-0.000536; mu= -6.5242+/- 0.032
mean_var=628.2799+/-139.728, 0's: 0 Z-trim(119.4): 1352 B-trim: 33 in 1/55
Lambda= 0.051168
statistics sampled from 31377 (33452) to 31377 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.737), E-opt: 0.2 (0.392), width: 16
Scan time: 9.120
The best scores are: opt bits E(85289)
NP_001034892 (OMIM: 610076) cyclin-dependent kinas ( 346) 2363 189.5 9.2e-48
XP_016870050 (OMIM: 610076) PREDICTED: cyclin-depe ( 351) 2343 188.0 2.6e-47
XP_016870051 (OMIM: 610076) PREDICTED: cyclin-depe ( 329) 1872 153.2 7.3e-37
NP_848519 (OMIM: 610076) cyclin-dependent kinase 2 ( 338) 1255 107.7 3.8e-23
NP_036251 (OMIM: 610076) cyclin-dependent kinase 2 ( 325) 1133 98.7 1.9e-20
NP_001164110 (OMIM: 610076) cyclin-dependent kinas ( 275) 1100 96.1 9.5e-20
XP_016870053 (OMIM: 610076) PREDICTED: cyclin-depe ( 303) 1100 96.2 1e-19
NP_001164111 (OMIM: 610076) cyclin-dependent kinas ( 243) 1089 95.2 1.6e-19
XP_016870052 (OMIM: 610076) PREDICTED: cyclin-depe ( 310) 1089 95.4 1.8e-19
NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 887 80.5 5.4e-15
NP_001790 (OMIM: 601955) cyclin-dependent kinase 7 ( 346) 844 77.4 5.2e-14
NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 ( 298) 830 76.2 9.9e-14
NP_001307847 (OMIM: 116940) cyclin-dependent kinas ( 297) 814 75.0 2.2e-13
NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 ( 297) 814 75.0 2.2e-13
XP_005270360 (OMIM: 116940) PREDICTED: cyclin-depe ( 297) 814 75.0 2.2e-13
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 813 75.0 2.3e-13
NP_277022 (OMIM: 176873) cyclin-dependent kinase 1 ( 526) 814 75.4 3e-13
NP_277025 (OMIM: 176873) cyclin-dependent kinase 1 ( 565) 814 75.5 3.2e-13
XP_011540798 (OMIM: 176873) PREDICTED: cyclin-depe ( 578) 814 75.5 3.2e-13
NP_277024 (OMIM: 176873) cyclin-dependent kinase 1 ( 748) 814 75.7 3.7e-13
XP_011540797 (OMIM: 176873) PREDICTED: cyclin-depe ( 760) 814 75.7 3.7e-13
XP_016858417 (OMIM: 176873) PREDICTED: cyclin-depe ( 761) 814 75.7 3.7e-13
XP_016858416 (OMIM: 176873) PREDICTED: cyclin-depe ( 770) 814 75.7 3.7e-13
XP_011540796 (OMIM: 176873) PREDICTED: cyclin-depe ( 770) 814 75.7 3.7e-13
NP_001278274 (OMIM: 176873) cyclin-dependent kinas ( 772) 814 75.7 3.7e-13
XP_016858415 (OMIM: 176873) PREDICTED: cyclin-depe ( 781) 814 75.7 3.7e-13
NP_277021 (OMIM: 176873) cyclin-dependent kinase 1 ( 782) 814 75.7 3.8e-13
XP_006711128 (OMIM: 176873) PREDICTED: cyclin-depe ( 785) 814 75.7 3.8e-13
XP_016858414 (OMIM: 176873) PREDICTED: cyclin-depe ( 791) 814 75.7 3.8e-13
XP_011540795 (OMIM: 176873) PREDICTED: cyclin-depe ( 794) 814 75.7 3.8e-13
NP_001778 (OMIM: 176873) cyclin-dependent kinase 1 ( 795) 814 75.7 3.8e-13
XP_011540794 (OMIM: 176873) PREDICTED: cyclin-depe ( 804) 814 75.7 3.8e-13
XP_011540793 (OMIM: 176873) PREDICTED: cyclin-depe ( 804) 814 75.7 3.8e-13
XP_011540792 (OMIM: 176873) PREDICTED: cyclin-depe ( 804) 814 75.7 3.8e-13
NP_277071 (OMIM: 116951) cyclin-dependent kinase 1 ( 770) 810 75.4 4.6e-13
NP_001300911 (OMIM: 116951) cyclin-dependent kinas ( 779) 810 75.4 4.6e-13
NP_076916 (OMIM: 116951) cyclin-dependent kinase 1 ( 780) 810 75.4 4.6e-13
NP_001300825 (OMIM: 116951) cyclin-dependent kinas ( 783) 810 75.4 4.6e-13
NP_001310998 (OMIM: 601955) cyclin-dependent kinas ( 305) 773 72.0 1.9e-12
NP_443714 (OMIM: 603464) cyclin-dependent kinase 1 ( 360) 747 70.2 7.7e-12
NP_002587 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 730 69.2 2.1e-11
NP_997667 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 730 69.2 2.1e-11
NP_997668 (OMIM: 169190) cyclin-dependent kinase 1 ( 504) 730 69.2 2.2e-11
XP_011507904 (OMIM: 169190) PREDICTED: cyclin-depe ( 542) 730 69.3 2.3e-11
XP_016856912 (OMIM: 169190) PREDICTED: cyclin-depe ( 572) 730 69.3 2.3e-11
XP_006721373 (OMIM: 603464) PREDICTED: cyclin-depe ( 343) 715 67.8 3.8e-11
XP_006721371 (OMIM: 603464) PREDICTED: cyclin-depe ( 354) 705 67.1 6.5e-11
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 709 67.7 6.5e-11
NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 709 67.7 6.5e-11
XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 709 67.7 6.5e-11
>>NP_001034892 (OMIM: 610076) cyclin-dependent kinase 20 (346 aa)
initn: 2363 init1: 2363 opt: 2363 Z-score: 978.5 bits: 189.5 E(85289): 9.2e-48
Smith-Waterman score: 2363; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346)
10 20 30 40 50 60
pF1KE3 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL
250 260 270 280 290 300
310 320 330 340
pF1KE3 PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
310 320 330 340
>>XP_016870050 (OMIM: 610076) PREDICTED: cyclin-dependen (351 aa)
initn: 1283 init1: 1283 opt: 2343 Z-score: 970.4 bits: 188.0 E(85289): 2.6e-47
Smith-Waterman score: 2343; 98.6% identity (98.6% similar) in 351 aa overlap (1-346:1-351)
10 20 30 40 50 60
pF1KE3 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVAT-----RWYRAPELL
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_016 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATSPLPRRWYRAPELL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 YGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 DYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPA
250 260 270 280 290 300
300 310 320 330 340
pF1KE3 HPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
310 320 330 340 350
>>XP_016870051 (OMIM: 610076) PREDICTED: cyclin-dependen (329 aa)
initn: 1082 init1: 1082 opt: 1872 Z-score: 782.8 bits: 153.2 E(85289): 7.3e-37
Smith-Waterman score: 1872; 98.3% identity (98.3% similar) in 286 aa overlap (1-281:1-286)
10 20 30 40 50 60
pF1KE3 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVAT-----RWYRAPELL
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_016 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATSPLPRRWYRAPELL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 YGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 DYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPA
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKMSYAWVPSPHDAAC
250 260 270 280 290 300
300 310 320 330 340
pF1KE3 HPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
XP_016 CCALCSLLSSPRGSPPSVLLHSSPACPSI
310 320
>>NP_848519 (OMIM: 610076) cyclin-dependent kinase 20 is (338 aa)
initn: 2018 init1: 1114 opt: 1255 Z-score: 536.5 bits: 107.7 E(85289): 3.8e-23
Smith-Waterman score: 2115; 90.5% identity (90.5% similar) in 359 aa overlap (1-346:1-338)
10 20 30 40
pF1KE3 MDQYCILGRIGEGAHGIVFKAKHVE-------------TGEIVALKKVALRRLEDGFPNQ
::::::::::::::::::::::::: ::::::::::::::::::::::
NP_848 MDQYCILGRIGEGAHGIVFKAKHVEPRVGWQCLPSILQTGEIVALKKVALRRLEDGFPNQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 ALREIKALQEMEDNQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSY
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 LQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 WYRAPELLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV
:::::::::::::::::::::::::::::::::::::::
NP_848 ---------------------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQV
190 200 210
230 240 250 260 270 280
pF1KE3 WPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 WPELTELPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQY
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE3 FFTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 FFTAPLPAHPSELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
280 290 300 310 320 330
>>NP_036251 (OMIM: 610076) cyclin-dependent kinase 20 is (325 aa)
initn: 2189 init1: 1114 opt: 1133 Z-score: 488.0 bits: 98.7 E(85289): 1.9e-20
Smith-Waterman score: 2151; 93.9% identity (93.9% similar) in 346 aa overlap (1-346:1-325)
10 20 30 40 50 60
pF1KE3 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ
:::::::::::::::::::::::::::::::::::::::::::::::
NP_036 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR-------------
130 140 150 160
190 200 210 220 230 240
pF1KE3 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 --------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI
170 180 190 200 210
250 260 270 280 290 300
pF1KE3 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL
220 230 240 250 260 270
310 320 330 340
pF1KE3 PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
280 290 300 310 320
>>NP_001164110 (OMIM: 610076) cyclin-dependent kinase 20 (275 aa)
initn: 1740 init1: 1089 opt: 1100 Z-score: 475.5 bits: 96.1 E(85289): 9.5e-20
Smith-Waterman score: 1680; 92.5% identity (92.5% similar) in 281 aa overlap (1-281:1-260)
10 20 30 40 50 60
pF1KE3 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR-------------
130 140 150 160
190 200 210 220 230 240
pF1KE3 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI
170 180 190 200 210
250 260 270 280 290 300
pF1KE3 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL
:::::::::::::::::::::::::::::::::::::::::
NP_001 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKLPCLPIHLSCRFLSV
220 230 240 250 260 270
310 320 330 340
pF1KE3 PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
>>XP_016870053 (OMIM: 610076) PREDICTED: cyclin-dependen (303 aa)
initn: 1718 init1: 1089 opt: 1100 Z-score: 475.1 bits: 96.2 E(85289): 1e-19
Smith-Waterman score: 1680; 92.5% identity (92.5% similar) in 281 aa overlap (1-281:1-260)
10 20 30 40 50 60
pF1KE3 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATR-------------
130 140 150 160
190 200 210 220 230 240
pF1KE3 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 --------SVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI
170 180 190 200 210
250 260 270 280 290 300
pF1KE3 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL
:::::::::::::::::::::::::::::::::::::::::
XP_016 SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKMSYAWVPSPHDAACCCALC
220 230 240 250 260 270
310 320 330 340
pF1KE3 PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
XP_016 SLLSSPRGSPPSVLLHSSPACPSI
280 290 300
>>NP_001164111 (OMIM: 610076) cyclin-dependent kinase 20 (243 aa)
initn: 1113 init1: 1089 opt: 1089 Z-score: 471.7 bits: 95.2 E(85289): 1.6e-19
Smith-Waterman score: 1089; 100.0% identity (100.0% similar) in 167 aa overlap (1-167:1-167)
10 20 30 40 50 60
pF1KE3 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRSSLSCRTTTRSPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI
NP_001 RSRCPCPWRRCCLTSLPRHWICWVNSFSTLLTSASQLPRLSSISTSSQLPCLPIHLSCRF
190 200 210 220 230 240
>>XP_016870052 (OMIM: 610076) PREDICTED: cyclin-dependen (310 aa)
initn: 1548 init1: 1089 opt: 1089 Z-score: 470.6 bits: 95.4 E(85289): 1.8e-19
Smith-Waterman score: 1480; 71.6% identity (77.3% similar) in 348 aa overlap (1-346:1-310)
10 20 30 40 50 60
pF1KE3 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ
::::::::::::::::::::::::::::::::::::::::::::::: . . .
XP_016 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRSSLSCRTTTRSPL
130 140 150 160 170 180
190 200 210 220 230
pF1KE3 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYV--LRILGTPNPQVWPELTELPDYN
.. : :. . .: . .:.: . : : :. :. : ..
XP_016 RSRCPCPWRRCCLTS--------LPR----HWICWVNSFSTLLTSASQL-PRCRMLGCHH
190 200 210 220
240 250 260 270 280 290
pF1KE3 KISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPS
.. :: : : : :. : . :::::::::::::::::
XP_016 LMT------------LPAVVPCA------------HSSPAPG-ALLHQYFFTAPLPAHPS
230 240 250 260
300 310 320 330 340
pF1KE3 ELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
270 280 290 300 310
>>NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 [Ho (305 aa)
initn: 826 init1: 374 opt: 887 Z-score: 390.1 bits: 80.5 E(85289): 5.4e-15
Smith-Waterman score: 887; 45.3% identity (73.3% similar) in 307 aa overlap (1-306:1-303)
10 20 30 40 50 60
pF1KE3 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
::.. . .::::..:.:.:::. :::..:::::. : .: :. :.:::. :.:..
NP_001 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELK-
10 20 30 40 50
70 80 90 100 110
pF1KE3 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQ-RPLAQAQVKSYLQMLLKGVAFCH
. .:.: : . . :.:::. .:: . . . : .:::: .::.::.:::
NP_001 HPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR
.. ..:::::: ::::. : .:.:::::::.:. : :::.:.: ::::::.: :..
NP_001 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVP-LRTYTHEVVTLWYRAPEILLGSK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK
: .::.::.:::..:... . :::: ..:.:: ..:.::::. ..:: .:.:::: :
NP_001 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDY-K
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 ISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSE
:: . . :::..:.. :.. ::: :.: : : :::.:. :: : :: ..: :. ..
NP_001 GSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF-SSPEPSPAAR
240 250 260 270 280 290
300 310 320 330 340
pF1KE3 LPIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
. ::.
NP_001 QYVLQRFRH
300
346 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:44:01 2016 done: Sun Nov 6 04:44:03 2016
Total Scan time: 9.120 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]