Result of FASTA (omim) for
pFN21AE1784
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1784, 292 aa
1>>>pF1KE1784 292 - 292 aa - 292 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7054+/-0.000352; mu= 18.1687+/- 0.022
mean_var=64.1981+/-13.041, 0's: 0 Z-trim(114.1): 50 B-trim: 0 in 0/51
Lambda= 0.160071
statistics sampled from 23640 (23707) to 23640 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.278), width: 16
Scan time: 6.730
The best scores are: opt bits E(85289)
NP_004916 (OMIM: 600170,607457) aquaporin-3 isofor ( 292) 1985 467.1 1.8e-131
NP_001305073 (OMIM: 600170,607457) aquaporin-3 iso ( 237) 1105 263.8 2.3e-70
NP_066190 (OMIM: 602914) aquaporin-9 isoform 1 [Ho ( 295) 952 228.5 1.2e-59
NP_536354 (OMIM: 606578) aquaporin-10 [Homo sapien ( 301) 931 223.7 3.4e-58
XP_016870189 (OMIM: 602974,614411) PREDICTED: aqua ( 341) 926 222.6 8.3e-58
XP_005251510 (OMIM: 602974,614411) PREDICTED: aqua ( 342) 926 222.6 8.4e-58
NP_001161 (OMIM: 602974,614411) aquaporin-7 isofor ( 342) 926 222.6 8.4e-58
XP_011516168 (OMIM: 602974,614411) PREDICTED: aqua ( 342) 926 222.6 8.4e-58
XP_011508406 (OMIM: 606578) PREDICTED: aquaporin-1 ( 302) 919 220.9 2.3e-57
XP_006716828 (OMIM: 602974,614411) PREDICTED: aqua ( 285) 841 202.9 5.9e-52
XP_011516169 (OMIM: 602974,614411) PREDICTED: aqua ( 285) 841 202.9 5.9e-52
NP_001307565 (OMIM: 602914) aquaporin-9 isoform 3 ( 230) 781 189.0 7.5e-48
NP_001305086 (OMIM: 602974,614411) aquaporin-7 iso ( 256) 781 189.0 8.1e-48
NP_001305087 (OMIM: 602974,614411) aquaporin-7 iso ( 257) 781 189.0 8.1e-48
NP_001305085 (OMIM: 602974,614411) aquaporin-7 iso ( 216) 733 177.9 1.5e-44
XP_016870192 (OMIM: 602974,614411) PREDICTED: aqua ( 250) 710 172.6 6.8e-43
XP_016870194 (OMIM: 602974,614411) PREDICTED: aqua ( 250) 710 172.6 6.8e-43
XP_016870191 (OMIM: 602974,614411) PREDICTED: aqua ( 250) 710 172.6 6.8e-43
XP_016870190 (OMIM: 602974,614411) PREDICTED: aqua ( 250) 710 172.6 6.8e-43
XP_016870193 (OMIM: 602974,614411) PREDICTED: aqua ( 250) 710 172.6 6.8e-43
XP_016870195 (OMIM: 602974,614411) PREDICTED: aqua ( 200) 696 169.3 5.4e-42
NP_001307564 (OMIM: 602914) aquaporin-9 isoform 2 ( 193) 550 135.6 7.5e-32
XP_005268895 (OMIM: 600442) PREDICTED: aquaporin-5 ( 222) 212 57.6 2.6e-08
NP_001642 (OMIM: 600442) aquaporin-5 [Homo sapiens ( 265) 212 57.6 3e-08
NP_001160 (OMIM: 603750) aquaporin-8 [Homo sapiens ( 261) 197 54.1 3.3e-07
XP_011544124 (OMIM: 603750) PREDICTED: aquaporin-8 ( 262) 197 54.2 3.3e-07
NP_036196 (OMIM: 154050,615274) lens fiber major i ( 263) 195 53.7 4.5e-07
NP_000477 (OMIM: 107777,125800) aquaporin-2 [Homo ( 271) 180 50.2 5.1e-06
NP_001304316 (OMIM: 600308) aquaporin-4 isoform de ( 296) 179 50.0 6.4e-06
NP_004019 (OMIM: 600308) aquaporin-4 isoform M23 [ ( 301) 179 50.0 6.5e-06
XP_011524244 (OMIM: 600308) PREDICTED: aquaporin-4 ( 316) 179 50.1 6.7e-06
NP_001641 (OMIM: 600308) aquaporin-4 isoform M1 [H ( 323) 179 50.1 6.8e-06
NP_001304313 (OMIM: 600308) aquaporin-4 isoform M1 ( 352) 179 50.1 7.3e-06
NP_001643 (OMIM: 601383) aquaporin-6 [Homo sapiens ( 282) 168 47.5 3.6e-05
NP_932766 (OMIM: 107776,110450) aquaporin-1 isofor ( 269) 158 45.2 0.00017
NP_001316801 (OMIM: 107776,110450) aquaporin-1 iso ( 323) 158 45.2 0.0002
XP_011544125 (OMIM: 603750) PREDICTED: aquaporin-8 ( 148) 145 41.9 0.00087
>>NP_004916 (OMIM: 600170,607457) aquaporin-3 isoform 1 (292 aa)
initn: 1985 init1: 1985 opt: 1985 Z-score: 2481.4 bits: 467.1 E(85289): 1.8e-131
Smith-Waterman score: 1985; 100.0% identity (100.0% similar) in 292 aa overlap (1-292:1-292)
10 20 30 40 50 60
pF1KE1 MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQ
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 HWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHVKHKEQI
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHVKHKEQI
250 260 270 280 290
>>NP_001305073 (OMIM: 600170,607457) aquaporin-3 isoform (237 aa)
initn: 1105 init1: 1105 opt: 1105 Z-score: 1384.3 bits: 263.8 E(85289): 2.3e-70
Smith-Waterman score: 1105; 100.0% identity (100.0% similar) in 164 aa overlap (1-164:1-164)
10 20 30 40 50 60
pF1KE1 MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTIN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 GLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVD
::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQDRPALVVGAHRVPTPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 PYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQ
NP_001 LHCGCLRVPADDRLPPGAAPTLQRGRECEAGPCEAQGADLSGQGPSPHSAALALSIH
190 200 210 220 230
>>NP_066190 (OMIM: 602914) aquaporin-9 isoform 1 [Homo s (295 aa)
initn: 964 init1: 918 opt: 952 Z-score: 1192.1 bits: 228.5 E(85289): 1.2e-59
Smith-Waterman score: 952; 51.6% identity (82.2% similar) in 258 aa overlap (15-272:16-273)
10 20 30 40 50
pF1KE1 MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTI
: .. : ...:.: :::.::...::: :::..:::: :: .::
NP_066 MQPEGAEKGKSFKQRLVLKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 NLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIV
:..:..::...: .:: :::.:.::::..:::...: :.:::.:. :: ::::.::. :
NP_066 NVGFSMAVAMAIYVAGGVSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 FGLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIV
::.:::.. :: ..:.. : :.:: ::::::. .:.. :.: :: ..: :.. :.::
NP_066 FGIYYDGLMSFAGGKLLIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE1 DPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTG
: : .::::: ...::...::..:.:.::: :.:::::..::::::::::: :: .:
NP_066 DSRNLGAPRGLEPIAIGLLIIVIASSLGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE1 QHWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHVKHKEQI
...::.:.:.::.:.. : ..: :.: : .:
NP_066 NNFWWIPVVGPLVGAVIGGLIYVLVIEIHHPEPDSVFKTEQSEDKPEKYELSVIM
250 260 270 280 290
>>NP_536354 (OMIM: 606578) aquaporin-10 [Homo sapiens] (301 aa)
initn: 978 init1: 918 opt: 931 Z-score: 1165.7 bits: 223.7 E(85289): 3.4e-58
Smith-Waterman score: 931; 50.2% identity (78.9% similar) in 279 aa overlap (14-289:11-284)
10 20 30 40 50
pF1KE1 MGRQKELVSRCGEMLHIRYR--LLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLT
: :.: : : :: ::: ::...:... :.:::.: : :.:.:.:
NP_536 MVFTQAPAEIMGHLRIRSLLARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFT
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 INLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGI
. :: ..:::..: ..:.::::::::: ..:::...: ::.::::: :.: :.:: ..:
NP_536 MFLAGSLAVTIAIYVGGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 VFGLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAI
.. ::.::. ... ..: :.::. ::.::::::. .:.. :::.:: .::. ::: .:::
NP_536 TYVLYHDALQNYTGGNLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 VDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTT
.: :. :: ::: .::...:..: ::: : : .:::::.:::::: .:::: ::..
NP_536 LDRRNKGVPAGLEPVVVGMLILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 GQHWWWVPIVSPLLGSIAGVFVYQLMIGCHL-EQPPPSNEEENVKLAHVKHKEQI
:. :::::.:.::.:. .:. .:::... : : : :... :. ..::
NP_536 GNGWWWVPVVAPLVGATVGTATYQLLVALHHPEGPEPAQD-----LVSAQHKASELETPA
240 250 260 270 280 290
NP_536 SAQMLECKL
300
>>XP_016870189 (OMIM: 602974,614411) PREDICTED: aquapori (341 aa)
initn: 929 init1: 818 opt: 926 Z-score: 1158.8 bits: 222.6 E(85289): 8.3e-58
Smith-Waterman score: 926; 47.2% identity (80.9% similar) in 267 aa overlap (7-273:20-283)
10 20 30 40
pF1KE1 MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQVV
.... :.:. ...:. ::: ..: ....:: ::::..:
XP_016 MGSGHCLRSTRGSKMVSWSVIAKIQEILQ--RKMVREFLAEFMSTYVMMVFGLGSVAHMV
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 LSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLA
:.. .:..: .::.:::.::.:. .::..::::.: ::::: : :.: :: :.:.:.:.
XP_016 LNK-KYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLG
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 QTLGAFLGAGIVFGLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIG
: ::.::.:. ...:.: :: ::. .::.:.:: .:::::::: :. . ::...
XP_016 QFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 TASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTA
:. : .:..::.: :::. : ::...:..:..::.:.:.:.:::.::.::. ::.::
XP_016 TGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFTF
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 LAGWGSAVFTTGQHWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHVK
.::::. ::..:..:::::.:.::::. : ..: ..:: . . :
XP_016 IAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHGI
240 250 260 270 280 290
290
pF1KE1 HKEQI
XP_016 TVLPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF
300 310 320 330 340
>>XP_005251510 (OMIM: 602974,614411) PREDICTED: aquapori (342 aa)
initn: 929 init1: 818 opt: 926 Z-score: 1158.8 bits: 222.6 E(85289): 8.4e-58
Smith-Waterman score: 926; 47.2% identity (80.9% similar) in 267 aa overlap (7-273:21-284)
10 20 30 40
pF1KE1 MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQV
.... :.:. ...:. ::: ..: ....:: ::::..
XP_005 MVQASGHRRSTRGSKMVSWSVIAKIQEILQ--RKMVREFLAEFMSTYVMMVFGLGSVAHM
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 VLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTL
::.. .:..: .::.:::.::.:. .::..::::.: ::::: : :.: :: :.:.:.:
XP_005 VLNK-KYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 AQTLGAFLGAGIVFGLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFI
.: ::.::.:. ...:.: :: ::. .::.:.:: .:::::::: :. . ::...
XP_005 GQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAW
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 GTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFT
:. : .:..::.: :::. : ::...:..:..::.:.:.:.:::.::.::. ::.::
XP_005 LTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFT
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 ALAGWGSAVFTTGQHWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHV
.::::. ::..:..:::::.:.::::. : ..: ..:: . . :
XP_005 FIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHG
240 250 260 270 280 290
290
pF1KE1 KHKEQI
XP_005 ITVLPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF
300 310 320 330 340
>>NP_001161 (OMIM: 602974,614411) aquaporin-7 isoform 1 (342 aa)
initn: 929 init1: 818 opt: 926 Z-score: 1158.8 bits: 222.6 E(85289): 8.4e-58
Smith-Waterman score: 926; 47.2% identity (80.9% similar) in 267 aa overlap (7-273:21-284)
10 20 30 40
pF1KE1 MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQV
.... :.:. ...:. ::: ..: ....:: ::::..
NP_001 MVQASGHRRSTRGSKMVSWSVIAKIQEILQ--RKMVREFLAEFMSTYVMMVFGLGSVAHM
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 VLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTL
::.. .:..: .::.:::.::.:. .::..::::.: ::::: : :.: :: :.:.:.:
NP_001 VLNK-KYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 AQTLGAFLGAGIVFGLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFI
.: ::.::.:. ...:.: :: ::. .::.:.:: .:::::::: :. . ::...
NP_001 GQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAW
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 GTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFT
:. : .:..::.: :::. : ::...:..:..::.:.:.:.:::.::.::. ::.::
NP_001 LTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFT
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 ALAGWGSAVFTTGQHWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHV
.::::. ::..:..:::::.:.::::. : ..: ..:: . . :
NP_001 FIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHG
240 250 260 270 280 290
290
pF1KE1 KHKEQI
NP_001 ITVLPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF
300 310 320 330 340
>>XP_011516168 (OMIM: 602974,614411) PREDICTED: aquapori (342 aa)
initn: 929 init1: 818 opt: 926 Z-score: 1158.8 bits: 222.6 E(85289): 8.4e-58
Smith-Waterman score: 926; 47.2% identity (80.9% similar) in 267 aa overlap (7-273:21-284)
10 20 30 40
pF1KE1 MGRQKELVSRCGEMLHIRYRLLRQALAECLGTLILVMFGCGSVAQV
.... :.:. ...:. ::: ..: ....:: ::::..
XP_011 MVQASGHRRSTRGSKMVSWSVIAKIQEILQ--RKMVREFLAEFMSTYVMMVFGLGSVAHM
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 VLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTL
::.. .:..: .::.:::.::.:. .::..::::.: ::::: : :.: :: :.:.:.:
XP_011 VLNK-KYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 AQTLGAFLGAGIVFGLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFI
.: ::.::.:. ...:.: :: ::. .::.:.:: .:::::::: :. . ::...
XP_011 GQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAW
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 GTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFT
:. : .:..::.: :::. : ::...:..:..::.:.:.:.:::.::.::. ::.::
XP_011 LTGMLQLCLFAITDQENNPALPGTEALVIGILVVIIGVSLGMNTGYAINPSRDLPPRIFT
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 ALAGWGSAVFTTGQHWWWVPIVSPLLGSIAGVFVYQLMIGCHLEQPPPSNEEENVKLAHV
.::::. ::..:..:::::.:.::::. : ..: ..:: . . :
XP_011 FIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIYLVFIGSTIPREPLKLEDSVAYEDHG
240 250 260 270 280 290
290
pF1KE1 KHKEQI
XP_011 ITVLPKMGSHEPTISPLTPVSVSPANRSSVHPAPPLHESMALEHF
300 310 320 330 340
>>XP_011508406 (OMIM: 606578) PREDICTED: aquaporin-10 is (302 aa)
initn: 957 init1: 849 opt: 919 Z-score: 1150.7 bits: 220.9 E(85289): 2.3e-57
Smith-Waterman score: 919; 50.0% identity (78.6% similar) in 280 aa overlap (14-289:11-285)
10 20 30 40 50
pF1KE1 MGRQKELVSRCGEMLHIRYR--LLRQALAECLGTLILV-MFGCGSVAQVVLSRGTHGGFL
: :.: : : :: ::: ::...:. .. :.:::.: : :.:.:.
XP_011 MVFTQAPAEIMGHLRIRSLLARQCLAEFLGVFVLMQLLTQGAVAQAVTSGETKGNFF
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 TINLAFGFAVTLGILIAGQVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAG
:. :: ..:::..: ..:.::::::::: ..:::...: ::.::::: :.: :.:: ..:
XP_011 TMFLAGSLAVTIAIYVGGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 IVFGLYYDAIWHFADNQLFVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLA
.. ::.::. ... ..: :.::. ::.::::::. .:.. :::.:: .::. ::: .::
XP_011 ATYVLYHDALQNYTGGNLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE1 IVDPYNNPVPRGLEAFTVGLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFT
:.: :. :: ::: .::...:..: ::: : : .:::::.:::::: .:::: ::.
XP_011 ILDRRNKGVPAGLEPVVVGMLILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 TGQHWWWVPIVSPLLGSIAGVFVYQLMIGCHL-EQPPPSNEEENVKLAHVKHKEQI
.:. :::::.:.::.:. .:. .:::... : : : :... :. ..::
XP_011 AGNGWWWVPVVAPLVGATVGTATYQLLVALHHPEGPEPAQD-----LVSAQHKASELETP
240 250 260 270 280 290
XP_011 ASAQMLECKL
300
>>XP_006716828 (OMIM: 602974,614411) PREDICTED: aquapori (285 aa)
initn: 860 init1: 818 opt: 841 Z-score: 1053.7 bits: 202.9 E(85289): 5.9e-52
Smith-Waterman score: 841; 49.6% identity (81.6% similar) in 228 aa overlap (46-273:1-227)
20 30 40 50 60 70
pF1KE1 HIRYRLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAG
.::.. .:..: .::.:::.::.:. .::
XP_006 MVLNK-KYGSYLGVNLGFGFGVTMGVHVAG
10 20
80 90 100 110 120 130
pF1KE1 QVSGAHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWHFADNQL
..::::.: ::::: : :.: :: :.:.:.:.: ::.::.:. ...:.: :: ::. .::
XP_006 RISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQL
30 40 50 60 70 80
140 150 160 170 180 190
pF1KE1 FVSGPNGTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTV
.:.:: .:::::::: :. . ::... :. : .:..::.: :::. : ::...
XP_006 MVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVI
90 100 110 120 130 140
200 210 220 230 240 250
pF1KE1 GLVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHWWWVPIVSPLLGSI
:..:..::.:.:.:.:::.::.::. ::.:: .::::. ::..:..:::::.:.::::.
XP_006 GILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAY
150 160 170 180 190 200
260 270 280 290
pF1KE1 AGVFVYQLMIGCHLEQPPPSNEEENVKLAHVKHKEQI
: ..: ..:: . . :
XP_006 LGGIIYLVFIGSTIPREPLKLEDSVAYEDHGITVLPKMGSHEPTISPLTPVSVSPANRSS
210 220 230 240 250 260
292 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:47:07 2016 done: Sun Nov 6 15:47:09 2016
Total Scan time: 6.730 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]