Result of FASTA (omim) for
pFN21AE2379
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2379, 1159 aa
1>>>pF1KE2379 1159 - 1159 aa - 1159 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4530+/-0.000378; mu= 5.0542+/- 0.024
mean_var=251.0289+/-51.872, 0's: 0 Z-trim(121.3): 88 B-trim: 1574 in 1/58
Lambda= 0.080949
statistics sampled from 37684 (37772) to 37684 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.746), E-opt: 0.2 (0.443), width: 16
Scan time: 16.540
The best scores are: opt bits E(85289)
NP_000229 (OMIM: 152427,609620,613688) potassium v (1159) 7844 930.0 0
XP_016867685 (OMIM: 152427,609620,613688) PREDICTE (1100) 7434 882.1 0
XP_011514487 (OMIM: 152427,609620,613688) PREDICTE (1059) 7140 847.8 0
XP_016867684 (OMIM: 152427,609620,613688) PREDICTE (1109) 7140 847.8 0
XP_011514488 (OMIM: 152427,609620,613688) PREDICTE ( 910) 6027 717.8 7.7e-206
NP_742053 (OMIM: 152427,609620,613688) potassium v ( 888) 5358 639.6 2.5e-182
NP_742054 (OMIM: 152427,609620,613688) potassium v ( 819) 5337 637.1 1.3e-181
XP_016860709 (OMIM: 608169) PREDICTED: potassium v (1189) 3984 479.3 6.3e-134
NP_150375 (OMIM: 608169) potassium voltage-gated c (1196) 3836 462.0 1e-128
XP_016860708 (OMIM: 608169) PREDICTED: potassium v (1193) 3805 458.4 1.2e-127
XP_016860707 (OMIM: 608169) PREDICTED: potassium v (1201) 3748 451.7 1.2e-125
XP_011510411 (OMIM: 608169) PREDICTED: potassium v (1204) 3124 378.8 1.1e-103
XP_011523610 (OMIM: 608168) PREDICTED: potassium v ( 918) 3078 373.4 3.6e-102
XP_011523611 (OMIM: 608168) PREDICTED: potassium v ( 915) 3077 373.3 3.9e-102
XP_016880669 (OMIM: 608168) PREDICTED: potassium v ( 871) 3076 373.1 4.1e-102
NP_110406 (OMIM: 608168) potassium voltage-gated c ( 994) 3076 373.2 4.6e-102
XP_016880664 (OMIM: 608168) PREDICTED: potassium v ( 994) 3076 373.2 4.6e-102
XP_016880665 (OMIM: 608168) PREDICTED: potassium v ( 983) 3048 369.9 4.4e-101
NP_001265849 (OMIM: 608168) potassium voltage-gate ( 835) 3031 367.9 1.5e-100
XP_016880666 (OMIM: 608168) PREDICTED: potassium v ( 958) 3031 367.9 1.7e-100
NP_001265848 (OMIM: 608168) potassium voltage-gate ( 958) 3031 367.9 1.7e-100
XP_016880667 (OMIM: 608168) PREDICTED: potassium v ( 947) 3030 367.8 1.8e-100
XP_011523613 (OMIM: 608168) PREDICTED: potassium v ( 726) 3010 365.4 7.5e-100
XP_011523614 (OMIM: 608168) PREDICTED: potassium v ( 726) 3010 365.4 7.5e-100
NP_775185 (OMIM: 608169) potassium voltage-gated c ( 732) 2954 358.8 7e-98
XP_011523615 (OMIM: 608168) PREDICTED: potassium v ( 711) 2951 358.5 8.7e-98
NP_001191727 (OMIM: 152427,609620,613688) potassiu ( 548) 2851 346.7 2.3e-94
XP_016860710 (OMIM: 608169) PREDICTED: potassium v ( 661) 1812 225.4 9.1e-58
NP_653234 (OMIM: 608260) potassium voltage-gated c (1107) 1627 204.0 4.3e-51
XP_016861188 (OMIM: 608260) PREDICTED: potassium v (1030) 1613 202.3 1.3e-50
XP_016861187 (OMIM: 608260) PREDICTED: potassium v (1108) 1613 202.3 1.3e-50
XP_016861190 (OMIM: 608260) PREDICTED: potassium v ( 930) 1605 201.4 2.2e-50
XP_016880668 (OMIM: 608168) PREDICTED: potassium v ( 941) 1543 194.1 3.4e-48
XP_011523612 (OMIM: 608168) PREDICTED: potassium v ( 905) 1498 188.8 1.3e-46
NP_775115 (OMIM: 608168) potassium voltage-gated c ( 905) 1498 188.8 1.3e-46
XP_016879891 (OMIM: 604528) PREDICTED: potassium v ( 957) 1442 182.3 1.2e-44
XP_016879890 (OMIM: 604528) PREDICTED: potassium v ( 968) 1442 182.3 1.2e-44
XP_016879889 (OMIM: 604528) PREDICTED: potassium v (1017) 1442 182.3 1.3e-44
NP_036417 (OMIM: 604528) potassium voltage-gated c (1017) 1442 182.3 1.3e-44
XP_016879892 (OMIM: 604528) PREDICTED: potassium v ( 532) 1119 144.4 1.8e-33
NP_002229 (OMIM: 135500,603305,611816) potassium v ( 962) 1118 144.5 3e-33
NP_647479 (OMIM: 605716) potassium voltage-gated c ( 988) 1086 140.8 4.1e-32
XP_016861189 (OMIM: 608260) PREDICTED: potassium v ( 986) 1027 133.9 4.9e-30
XP_016874586 (OMIM: 604527) PREDICTED: potassium v ( 720) 986 129.0 1.1e-28
NP_001300959 (OMIM: 604527) potassium voltage-gate (1023) 986 129.1 1.4e-28
NP_036416 (OMIM: 604527) potassium voltage-gated c (1083) 986 129.1 1.5e-28
XP_016874585 (OMIM: 604527) PREDICTED: potassium v (1016) 974 127.7 3.7e-28
XP_011536388 (OMIM: 604527) PREDICTED: potassium v (1034) 974 127.7 3.7e-28
XP_011536387 (OMIM: 604527) PREDICTED: potassium v (1094) 974 127.7 3.9e-28
XP_016856735 (OMIM: 135500,603305,611816) PREDICTE ( 597) 943 123.9 3e-27
>>NP_000229 (OMIM: 152427,609620,613688) potassium volta (1159 aa)
initn: 7844 init1: 7844 opt: 7844 Z-score: 4961.9 bits: 930.0 E(85289): 0
Smith-Waterman score: 7844; 100.0% identity (100.0% similar) in 1159 aa overlap (1-1159:1-1159)
10 20 30 40 50 60
pF1KE2 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTE
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 QPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 PRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 SLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 VTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPG
1090 1100 1110 1120 1130 1140
1150
pF1KE2 QLGALTSQPLHRHGSDPGS
:::::::::::::::::::
NP_000 QLGALTSQPLHRHGSDPGS
1150
>>XP_016867685 (OMIM: 152427,609620,613688) PREDICTED: p (1100 aa)
initn: 7434 init1: 7434 opt: 7434 Z-score: 4703.4 bits: 882.1 E(85289): 0
Smith-Waterman score: 7434; 100.0% identity (100.0% similar) in 1100 aa overlap (60-1159:1-1100)
30 40 50 60 70 80
pF1KE2 IIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGA
::::::::::::::::::::::::::::::
XP_016 MQRPCTCDFLHGPRTQRRAAAQIAQALLGA
10 20 30
90 100 110 120 130 140
pF1KE2 EERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRG
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 PPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSES
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE2 LALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLAR
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE2 TRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRT
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE2 ISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYK
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE2 LQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYAC
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE2 QPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFD
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE2 LLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWY
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE2 AIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGN
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE2 VSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQI
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE2 PNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKG
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE2 CLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPL
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE2 NLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIP
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE2 GSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGE
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE2 SPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSG
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE2 AFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQL
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE2 NRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLS
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150
pF1KE2 QVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
1060 1070 1080 1090 1100
>>XP_011514487 (OMIM: 152427,609620,613688) PREDICTED: p (1059 aa)
initn: 7140 init1: 7140 opt: 7140 Z-score: 4518.1 bits: 847.8 E(85289): 0
Smith-Waterman score: 7140; 100.0% identity (100.0% similar) in 1057 aa overlap (103-1159:3-1059)
80 90 100 110 120 130
pF1KE2 RTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVV
::::::::::::::::::::::::::::::
XP_011 MAGSCFLCLVDVVPVKNEDGAVIMFILNFEVV
10 20 30
140 150 160 170 180 190
pF1KE2 MEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPG
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE2 AVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPR
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE2 AHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLR
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE2 SGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTE
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE2 KVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFL
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE2 LKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVH
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE2 YFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFL
400 410 420 430 440 450
560 570 580 590 600 610
pF1KE2 LMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYV
460 470 480 490 500 510
620 630 640 650 660 670
pF1KE2 TALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTAR
520 530 540 550 560 570
680 690 700 710 720 730
pF1KE2 YHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL
580 590 600 610 620 630
740 750 760 770 780 790
pF1KE2 NRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG
640 650 660 670 680 690
800 810 820 830 840 850
pF1KE2 DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHF
700 710 720 730 740 750
860 870 880 890 900 910
pF1KE2 WSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGR
760 770 780 790 800 810
920 930 940 950 960 970
pF1KE2 AGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEP
820 830 840 850 860 870
980 990 1000 1010 1020 1030
pF1KE2 LMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGR
880 890 900 910 920 930
1040 1050 1060 1070 1080 1090
pF1KE2 RPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTS
940 950 960 970 980 990
1100 1110 1120 1130 1140 1150
pF1KE2 PLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHR
1000 1010 1020 1030 1040 1050
pF1KE2 HGSDPGS
:::::::
XP_011 HGSDPGS
>>XP_016867684 (OMIM: 152427,609620,613688) PREDICTED: p (1109 aa)
initn: 7140 init1: 7140 opt: 7140 Z-score: 4517.8 bits: 847.8 E(85289): 0
Smith-Waterman score: 7140; 100.0% identity (100.0% similar) in 1057 aa overlap (103-1159:53-1109)
80 90 100 110 120 130
pF1KE2 RTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVV
::::::::::::::::::::::::::::::
XP_016 VRGQEWLLQGDPDRAPELRALGRGCEGLGCGSCFLCLVDVVPVKNEDGAVIMFILNFEVV
30 40 50 60 70 80
140 150 160 170 180 190
pF1KE2 MEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPG
90 100 110 120 130 140
200 210 220 230 240 250
pF1KE2 AVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPR
150 160 170 180 190 200
260 270 280 290 300 310
pF1KE2 AHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLR
210 220 230 240 250 260
320 330 340 350 360 370
pF1KE2 SGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTE
270 280 290 300 310 320
380 390 400 410 420 430
pF1KE2 KVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFL
330 340 350 360 370 380
440 450 460 470 480 490
pF1KE2 LKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVH
390 400 410 420 430 440
500 510 520 530 540 550
pF1KE2 YFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFL
450 460 470 480 490 500
560 570 580 590 600 610
pF1KE2 LMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYV
510 520 530 540 550 560
620 630 640 650 660 670
pF1KE2 TALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTAR
570 580 590 600 610 620
680 690 700 710 720 730
pF1KE2 YHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHL
630 640 650 660 670 680
740 750 760 770 780 790
pF1KE2 NRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG
690 700 710 720 730 740
800 810 820 830 840 850
pF1KE2 DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHF
750 760 770 780 790 800
860 870 880 890 900 910
pF1KE2 WSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGR
810 820 830 840 850 860
920 930 940 950 960 970
pF1KE2 AGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEP
870 880 890 900 910 920
980 990 1000 1010 1020 1030
pF1KE2 LMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGR
930 940 950 960 970 980
1040 1050 1060 1070 1080 1090
pF1KE2 RPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTS
990 1000 1010 1020 1030 1040
1100 1110 1120 1130 1140 1150
pF1KE2 PLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHR
1050 1060 1070 1080 1090 1100
pF1KE2 HGSDPGS
:::::::
XP_016 HGSDPGS
>>XP_011514488 (OMIM: 152427,609620,613688) PREDICTED: p (910 aa)
initn: 6024 init1: 6024 opt: 6027 Z-score: 3816.5 bits: 717.8 E(85289): 7.7e-206
Smith-Waterman score: 6027; 99.6% identity (99.6% similar) in 902 aa overlap (1-902:1-902)
10 20 30 40 50 60
pF1KE2 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKAPG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 QPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSS
:
XP_011 PPESRRVGSP
910
>>NP_742053 (OMIM: 152427,609620,613688) potassium volta (888 aa)
initn: 5358 init1: 5358 opt: 5358 Z-score: 3394.4 bits: 639.6 E(85289): 2.5e-182
Smith-Waterman score: 5358; 100.0% identity (100.0% similar) in 800 aa overlap (1-800:1-800)
10 20 30 40 50 60
pF1KE2 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 PRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 RHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 PKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 TAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 EVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 RYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 AIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 PECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALY
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 FISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE
::::::::::::::::::::
NP_742 FISRGSIEILRGDVVVAILGMGWGAGTGLEMPSAASRGASLLNMQSLGLWTWDCLQGHWA
790 800 810 820 830 840
>>NP_742054 (OMIM: 152427,609620,613688) potassium volta (819 aa)
initn: 5335 init1: 5335 opt: 5337 Z-score: 3381.6 bits: 637.1 E(85289): 1.3e-181
Smith-Waterman score: 5337; 98.9% identity (99.4% similar) in 795 aa overlap (366-1159:25-819)
340 350 360 370 380 390
pF1KE2 ITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQ-VLSLGADVLPEYKLQAPR
:. .. :.: ::::::::::::::::::
NP_742 MAAPAGKASRTGALRPRAQKGRVRRAVRISSLVAQEVLSLGADVLPEYKLQAPR
10 20 30 40 50
400 410 420 430 440 450
pF1KE2 IHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 IHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAV
60 70 80 90 100 110
460 470 480 490 500 510
pF1KE2 VDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 VDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFG
120 130 140 150 160 170
520 530 540 550 560 570
pF1KE2 SGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 SGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNM
180 190 200 210 220 230
580 590 600 610 620 630
pF1KE2 EQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 EQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNT
240 250 260 270 280 290
640 650 660 670 680 690
pF1KE2 NSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 NSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLR
300 310 320 330 340 350
700 710 720 730 740 750
pF1KE2 QRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 QRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRAL
360 370 380 390 400 410
760 770 780 790 800 810
pF1KE2 AMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 AMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYAR
420 430 440 450 460 470
820 830 840 850 860 870
pF1KE2 PGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 PGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGS
480 490 500 510 520 530
880 890 900 910 920 930
pF1KE2 TELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 TELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSG
540 550 560 570 580 590
940 950 960 970 980 990
pF1KE2 PSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 PSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGV
600 610 620 630 640 650
1000 1010 1020 1030 1040 1050
pF1KE2 SNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 SNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLET
660 670 680 690 700 710
1060 1070 1080 1090 1100 1110
pF1KE2 RLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_742 RLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQF
720 730 740 750 760 770
1120 1130 1140 1150
pF1KE2 MACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
:::::::::::::::::::::::::::::::::::::::::::::
NP_742 MACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
780 790 800 810
>>XP_016860709 (OMIM: 608169) PREDICTED: potassium volta (1189 aa)
initn: 3272 init1: 1599 opt: 3984 Z-score: 2525.4 bits: 479.3 E(85289): 6.3e-134
Smith-Waterman score: 4185; 60.8% identity (77.5% similar) in 1149 aa overlap (1-1120:1-1105)
10 20 30 40 50 60
pF1KE2 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
::::::::::::::: :::::::::..:::::::::.:::.:::::::::. :.:: .::
XP_016 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
:.::::::::::.:.:. :::::::::.::::::...:.:.:: :.: . ..::::..:
XP_016 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
...:::.::: : ... ...: .: : . : : .:.:.: .:: :..:.
XP_016 VAMMFIINFEYVTDNENAATP-----ERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSL
130 140 150 160 170
190 200 210 220 230
pF1KE2 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPG--
. : .::.: . :..:.:. . . .. . . :.. .::. :.
XP_016 PQED------PDVVVID----SSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKC
180 190 200 210 220
240 250 260 270 280 290
pF1KE2 SPPRSAPGQLP--SPRAH--SLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAG
:: . : : ::. . : :: :: .:...::::: :.:::::. :::.. :
XP_016 SPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGF--G
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE2 VLPPP---PRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLAS
: : :::: : .. ..:.::.:::::.: .: ::.::::.:::: ..: . .:
XP_016 VHPKNIFRDRHASEGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSS
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE2 P-TSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVW
: .::. :::::.:.::::::::::::::::::::::::::.:::...::::::::::::
XP_016 PPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVW
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE2 DWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILIN
::::::::::::.::::::::::.. :: ::::.:.:: :::::::::::.:::::
XP_016 DWLILLLVIYTAIFTPYSAAFLLNDREE-QKRRECGYSCSPLNVVDLIVDIMFIIDILIN
410 420 430 440 450 460
480 490 500 510 520
pF1KE2 FRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEE---LIGLLKTA
::::::: :::::: :..::.::::::::::::::::::::::::::.: ::::::::
XP_016 FRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTA
470 480 490 500 510 520
530 540 550 560 570 580
pF1KE2 RLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLH
:::::::::::::::::::::::.:::: :::::::::::::::::.:.:.. ..::::
XP_016 RLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLD
530 540 550 560 570 580
590 600 610 620 630 640
pF1KE2 NLGDQIGKPYNSS-GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML
.::.:::: ::.: . .:::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVML
590 600 610 620 630 640
650 660 670 680 690 700
pF1KE2 IGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWS
:::::::::::::::::::::::::::: :::::.::::::::::::::::::::::::.
XP_016 IGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWT
650 660 670 680 690 700
710 720 730 740 750 760
pF1KE2 YTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPG
:::::::: ::::::::::::::::::..:::.:: ::::.:::::::::::::::::::
XP_016 YTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPG
710 720 730 740 750 760
770 780 790 800 810 820
pF1KE2 DTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALT
::::: ::.::::::.::::::::. :.::::::::::::: ..:::.:::::.::::::
XP_016 DTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALT
770 780 790 800 810 820
830 840 850 860 870 880
pF1KE2 YCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPG---SPGSTELEGGFSR
:::::::.:.:::::::::::::::: ..::.::::: . : . .. :: .
XP_016 YCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAKADLLRSQSMNDSEGDNCK
830 840 850 860 870 880
890 900 910 920 930 940
pF1KE2 QRKRKLSFRRRTDKD--TEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESS
:.:::::. . .:. :..: : :: ::. . . :. : . : :
XP_016 LRRRKLSFESEGEKENSTNDP-EDSA---DTIRHYQSSKRH----FEEKKSRSSSFISSI
890 900 910 920 930
950 960 970 980 990 1000
pF1KE2 EDEGPGRSSSPLRLVPFSSPRPPGEPPG-GEPLMEDCEKSSDTCNPLSGAFSGVSNIFSF
.:: ..:: ::. . :: :. : :.. : :: . . :
XP_016 DDE-----QKPL----FSGIVDSS--PGIGKASGLDFEETV----PTSGRMHIDKRSHSC
940 950 960 970
1010 1020 1030 1040 1050
pF1KE2 WGDSRGRQYQELPRCPAP---TPSLLNIPL----SSPGRRPRGDVESRLDALQRQLNRLE
. :.... : : .:: :. . . :.::.::: ::.::::::
XP_016 KDITDMRSWERENAHPQPEDSSPSALQRAAWGISETESDLTYGEVEQRLDLLQEQLNRLE
980 990 1000 1010 1020 1030
1060 1070 1080 1090 1100 1110
pF1KE2 TRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVS-PLPTLTLD-SLSQV
.....:. :.:::::.: :.:::::: ::. . :. .: : .. : :.:
XP_016 SQMTTDIQTILQLLQKQTTVVPPAYSMVTAGSEYQRPIIQLMRTSQPEASIKTDRSFSPS
1040 1050 1060 1070 1080 1090
1120 1130 1140 1150
pF1KE2 SQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
:: : :.
XP_016 SQ---CPEFLDLEKSKLKSKESLSSGVHLNTASEDNLTSLLKQDSDLSLELHLRQRKTYV
1100 1110 1120 1130 1140 1150
>>NP_150375 (OMIM: 608169) potassium voltage-gated chann (1196 aa)
initn: 2938 init1: 1599 opt: 3836 Z-score: 2432.0 bits: 462.0 E(85289): 1e-128
Smith-Waterman score: 4161; 60.5% identity (77.0% similar) in 1156 aa overlap (1-1120:1-1112)
10 20 30 40 50 60
pF1KE2 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
::::::::::::::: :::::::::..:::::::::.:::.:::::::::. :.:: .::
NP_150 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
:.::::::::::.:.:. :::::::::.::::::...:.:.:: :.: . ..::::..:
NP_150 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
...:::.::: : ... ...: .: : . : : .:.:.: .:: :..:.
NP_150 VAMMFIINFEYVTDNENAATP-----ERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSL
130 140 150 160 170
190 200 210 220 230
pF1KE2 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPG--
. : .::.: . :..:.:. . . .. . . :.. .::. :.
NP_150 PQED------PDVVVID----SSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKC
180 190 200 210 220
240 250 260 270 280 290
pF1KE2 SPPRSAPGQLP--SPRAH--SLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAG
:: . : : ::. . : :: :: .:...::::: :.:::::. :::.. :
NP_150 SPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGF--G
230 240 250 260 270 280
300 310 320 330 340
pF1KE2 VLPPP---PRHAST-------GAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLK
: : :::: : .. ..:.::.:::::.: .: ::.::::.:::: ..:
NP_150 VHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVK
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE2 GDPFLASP-TSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHY
. .:: .::. :::::.:.::::::::::::::::::::::::::.:::...:::::
NP_150 TEKKNSSPPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHY
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE2 SPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMF
:::::::::::::::::::.::::::::::.. :: ::::.:.:: ::::::::::
NP_150 SPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREE-QKRRECGYSCSPLNVVDLIVDIMF
410 420 430 440 450 460
470 480 490 500 510 520
pF1KE2 IVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEE---L
:.:::::::::::: :::::: :..::.::::::::::::::::::::::::::.: :
NP_150 IIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTL
470 480 490 500 510 520
530 540 550 560 570 580
pF1KE2 IGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMD
::::::::::::::::::::::::::::::.:::: :::::::::::::::::.:.:..
NP_150 IGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLT
530 540 550 560 570 580
590 600 610 620 630
pF1KE2 SRIGWLHNLGDQIGKPYNSS-GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKI
..:::: .::.:::: ::.: . .::::::::::::::::::::::::::::::::::::
NP_150 DKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKI
590 600 610 620 630 640
640 650 660 670 680 690
pF1KE2 FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEE
::::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::
NP_150 FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEE
650 660 670 680 690 700
700 710 720 730 740 750
pF1KE2 YFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFK
::::::.:::::::: ::::::::::::::::::..:::.:: ::::.::::::::::::
NP_150 YFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFK
710 720 730 740 750 760
760 770 780 790 800 810
pF1KE2 TTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSN
:::::::::::: ::.::::::.::::::::. :.::::::::::::: ..:::.:::::
NP_150 TTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSN
770 780 790 800 810 820
820 830 840 850 860 870
pF1KE2 GDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPG---SPGSTE
.:::::::::::::.:.:::::::::::::::: ..::.::::: . : . ..
NP_150 ADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAKADLLRSQSMND
830 840 850 860 870 880
880 890 900 910 920 930
pF1KE2 LEGGFSRQRKRKLSFRRRTDKD--TEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSG
:: . :.:::::. . .:. :..: : :: ::. . . :. : .
NP_150 SEGDNCKLRRRKLSFESEGEKENSTNDP-EDSA---DTIRHYQSSKRH----FEEKKSRS
890 900 910 920 930
940 950 960 970 980 990
pF1KE2 PSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPG-GEPLMEDCEKSSDTCNPLSGAFSG
: : .:: ..:: ::. . :: :. : :.. : :: .
NP_150 SSFISSIDDE-----QKPL----FSGIVDSS--PGIGKASGLDFEETV----PTSGRMHI
940 950 960 970
1000 1010 1020 1030 1040
pF1KE2 VSNIFSFWGDSRGRQYQELPRCPAP---TPSLLNIPL----SSPGRRPRGDVESRLDALQ
. : . :.... : : .:: :. . . :.::.::: ::
NP_150 DKRSHSCKDITDMRSWERENAHPQPEDSSPSALQRAAWGISETESDLTYGEVEQRLDLLQ
980 990 1000 1010 1020 1030
1050 1060 1070 1080 1090 1100
pF1KE2 RQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVS-PLPTLTL
.::::::.....:. :.:::::.: :.:::::: ::. . :. .: : ..
NP_150 EQLNRLESQMTTDIQTILQLLQKQTTVVPPAYSMVTAGSEYQRPIIQLMRTSQPEASIKT
1040 1050 1060 1070 1080 1090
1110 1120 1130 1140 1150
pF1KE2 D-SLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
: :.: :: : :.
NP_150 DRSFSPSSQ---CPEFLDLEKSKLKSKESLSSGVHLNTASEDNLTSLLKQDSDLSLELHL
1100 1110 1120 1130 1140 1150
>>XP_016860708 (OMIM: 608169) PREDICTED: potassium volta (1193 aa)
initn: 1866 init1: 1625 opt: 3805 Z-score: 2412.4 bits: 458.4 E(85289): 1.2e-127
Smith-Waterman score: 4129; 60.2% identity (76.7% similar) in 1156 aa overlap (1-1120:1-1109)
10 20 30 40 50 60
pF1KE2 MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVM
::::::::::::::: :::::::::..:::::::::.:::.:::::::::. :.:: .::
XP_016 MPVRRGHVAPQNTFLGTIIRKFEGQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDG
:.::::::::::.:.:. :::::::::.::::::...:.:.:: :.: . ..::::..:
XP_016 QKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSV
...:::.::: : ... ...: .: : . : : .:.:.: .:: :..:.
XP_016 VAMMFIINFEYVTDNENAATP-----ERVNPILPIKTVNRKFFGFKFPGLRVLTYRKQSL
130 140 150 160 170
190 200 210 220 230
pF1KE2 RSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPG--
. : .::.: . :..:.:. . . .. . . :.. .::. :.
XP_016 PQED------PDVVVID----SSKHSDDSVAMKHFKSPTKESCSPSEADDTKALIQPSKC
180 190 200 210 220
240 250 260 270 280 290
pF1KE2 SPPRSAPGQLP--SPRAH--SLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAG
:: . : : ::. . : :: :: .:...::::: :.:::::. :::.. :
XP_016 SPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGF--G
230 240 250 260 270 280
300 310 320 330 340
pF1KE2 VLPPP---PRHAST-------GAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLK
: : :::: : .. ..:.::.:::::.: .: ::.::::.:::: ..:
XP_016 VHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVK
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE2 GDPFLASP-TSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHY
. .:: .::. :::::.:.::::::::::::::::::::::::::.:::...:::::
XP_016 TEKKNSSPPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHY
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE2 SPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMF
:::::::::::::::::::.::::::::::.. :: ::::.:.:: ::::::::::
XP_016 SPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREE-QKRRECGYSCSPLNVVDLIVDIMF
410 420 430 440 450 460
470 480 490 500 510 520
pF1KE2 IVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEE---L
:.:::::::::::: :::::: :..::.::::::::::::::::::::::::::.: :
XP_016 IIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTL
470 480 490 500 510 520
530 540 550 560 570 580
pF1KE2 IGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMD
::::::::::::::::::::::::::::::.:::: :::::::::::::::::.:.:..
XP_016 IGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLT
530 540 550 560 570 580
590 600 610 620 630
pF1KE2 SRIGWLHNLGDQIGKPYNSS-GLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKI
..:::: .::.:::: ::.: . .::::::::::::::::::::::::::::::::::::
XP_016 DKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKI
590 600 610 620 630 640
640 650 660 670 680 690
pF1KE2 FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEE
::::::::::::::::::::::::::::::::::: :::::.::::::::::::::::::
XP_016 FSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEE
650 660 670 680 690 700
700 710 720 730 740 750
pF1KE2 YFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFK
::::::.:::::::: :::::::::::::::..:::.:: ::::.::::::::::::
XP_016 YFQHAWTYTNGIDMNM---GFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFK
710 720 730 740 750
760 770 780 790 800 810
pF1KE2 TTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSN
:::::::::::: ::.::::::.::::::::. :.::::::::::::: ..:::.:::::
XP_016 TTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSN
760 770 780 790 800 810
820 830 840 850 860 870
pF1KE2 GDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPG---SPGSTE
.:::::::::::::.:.:::::::::::::::: ..::.::::: . : . ..
XP_016 ADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAKADLLRSQSMND
820 830 840 850 860 870
880 890 900 910 920 930
pF1KE2 LEGGFSRQRKRKLSFRRRTDKD--TEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSG
:: . :.:::::. . .:. :..: : :: ::. . . :. : .
XP_016 SEGDNCKLRRRKLSFESEGEKENSTNDP-EDSA---DTIRHYQSSKRH----FEEKKSRS
880 890 900 910 920 930
940 950 960 970 980 990
pF1KE2 PSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPG-GEPLMEDCEKSSDTCNPLSGAFSG
: : .:: ..:: ::. . :: :. : :.. : :: .
XP_016 SSFISSIDDE-----QKPL----FSGIVDSS--PGIGKASGLDFEETV----PTSGRMHI
940 950 960 970
1000 1010 1020 1030 1040
pF1KE2 VSNIFSFWGDSRGRQYQELPRCPAP---TPSLLNIPL----SSPGRRPRGDVESRLDALQ
. : . :.... : : .:: :. . . :.::.::: ::
XP_016 DKRSHSCKDITDMRSWERENAHPQPEDSSPSALQRAAWGISETESDLTYGEVEQRLDLLQ
980 990 1000 1010 1020 1030
1050 1060 1070 1080 1090 1100
pF1KE2 RQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVS-PLPTLTL
.::::::.....:. :.:::::.: :.:::::: ::. . :. .: : ..
XP_016 EQLNRLESQMTTDIQTILQLLQKQTTVVPPAYSMVTAGSEYQRPIIQLMRTSQPEASIKT
1040 1050 1060 1070 1080 1090
1110 1120 1130 1140 1150
pF1KE2 D-SLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS
: :.: :: : :.
XP_016 DRSFSPSSQ---CPEFLDLEKSKLKSKESLSSGVHLNTASEDNLTSLLKQDSDLSLELHL
1100 1110 1120 1130 1140 1150
1159 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 16:14:20 2016 done: Sun Nov 6 16:14:22 2016
Total Scan time: 16.540 Total Display time: 0.320
Function used was FASTA [36.3.4 Apr, 2011]