Result of FASTA (omim) for
pFN21AE1847
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1847, 365 aa
1>>>pF1KE1847 365 - 365 aa - 365 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3177+/-0.000351; mu= 16.9737+/- 0.022
mean_var=71.7640+/-14.177, 0's: 0 Z-trim(114.9): 76 B-trim: 128 in 1/50
Lambda= 0.151398
statistics sampled from 24927 (25003) to 24927 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.293), width: 16
Scan time: 7.670
The best scores are: opt bits E(85289)
NP_476509 (OMIM: 606267) protein Wnt-16 isoform 1 ( 365) 2594 575.7 5.8e-164
NP_057171 (OMIM: 606267) protein Wnt-16 isoform 2 ( 355) 2375 527.8 1.4e-149
NP_478679 (OMIM: 601967) protein Wnt-7b precursor ( 349) 1131 256.1 8.8e-68
XP_011528668 (OMIM: 601967) PREDICTED: protein Wnt ( 353) 1131 256.1 8.9e-68
NP_004616 (OMIM: 228930,276820,601570) protein Wnt ( 349) 1083 245.6 1.3e-64
NP_110402 (OMIM: 606361) protein Wnt-5b precursor ( 359) 1037 235.6 1.4e-61
NP_116031 (OMIM: 606361) protein Wnt-5b precursor ( 359) 1037 235.6 1.4e-61
XP_011532393 (OMIM: 228930,276820,601570) PREDICTE ( 282) 1009 229.4 7.8e-60
XP_016862617 (OMIM: 164975,180700) PREDICTED: prot ( 365) 990 225.3 1.7e-58
XP_011532389 (OMIM: 164975,180700) PREDICTED: prot ( 365) 990 225.3 1.7e-58
XP_011532391 (OMIM: 164975,180700) PREDICTED: prot ( 365) 990 225.3 1.7e-58
NP_001243034 (OMIM: 164975,180700) protein Wnt-5a ( 365) 990 225.3 1.7e-58
XP_011532390 (OMIM: 164975,180700) PREDICTED: prot ( 365) 990 225.3 1.7e-58
XP_011532387 (OMIM: 164975,180700) PREDICTED: prot ( 365) 990 225.3 1.7e-58
XP_011532388 (OMIM: 164975,180700) PREDICTED: prot ( 365) 990 225.3 1.7e-58
XP_006713387 (OMIM: 164975,180700) PREDICTED: prot ( 365) 990 225.3 1.7e-58
NP_003383 (OMIM: 164975,180700) protein Wnt-5a iso ( 380) 990 225.3 1.8e-58
XP_016862616 (OMIM: 164975,180700) PREDICTED: prot ( 394) 990 225.3 1.8e-58
NP_005421 (OMIM: 164820,615220,615221) proto-oncog ( 370) 966 220.1 6.5e-57
NP_110388 (OMIM: 158330,603490,611812) protein Wnt ( 351) 930 212.2 1.5e-54
XP_011539900 (OMIM: 158330,603490,611812) PREDICTE ( 296) 929 211.9 1.5e-54
XP_011539899 (OMIM: 158330,603490,611812) PREDICTE ( 373) 929 212.0 1.8e-54
XP_011543542 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 907 207.2 4.9e-53
XP_011543540 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 907 207.2 4.9e-53
XP_011543541 (OMIM: 603699) PREDICTED: protein Wnt ( 364) 907 207.2 4.9e-53
NP_001278809 (OMIM: 601968) protein Wnt-2b isoform ( 299) 876 200.3 4.6e-51
NP_004176 (OMIM: 601968) protein Wnt-2b isoform WN ( 372) 876 200.4 5.4e-51
NP_078613 (OMIM: 601968) protein Wnt-2b isoform WN ( 391) 876 200.4 5.6e-51
NP_003382 (OMIM: 147870) protein Wnt-2 precursor [ ( 360) 875 200.2 6.2e-51
NP_149122 (OMIM: 606359) protein Wnt-3a precursor ( 352) 867 198.4 2e-50
XP_011542621 (OMIM: 606359) PREDICTED: protein Wnt ( 446) 867 198.5 2.5e-50
NP_110380 (OMIM: 165330,273395) proto-oncogene Wnt ( 355) 847 194.1 4.2e-49
XP_005274288 (OMIM: 603699) PREDICTED: protein Wnt ( 354) 845 193.6 5.7e-49
NP_004617 (OMIM: 603699) protein Wnt-11 precursor ( 354) 845 193.6 5.7e-49
XP_011543543 (OMIM: 603699) PREDICTED: protein Wnt ( 251) 836 191.6 1.7e-48
XP_016873730 (OMIM: 603699) PREDICTED: protein Wnt ( 251) 836 191.6 1.7e-48
NP_006513 (OMIM: 604663) protein Wnt-6 precursor [ ( 365) 740 170.7 4.7e-42
NP_003387 (OMIM: 602864) protein Wnt-9b isoform 1 ( 357) 699 161.7 2.3e-39
XP_011523480 (OMIM: 602864) PREDICTED: protein Wnt ( 363) 699 161.7 2.3e-39
XP_011537024 (OMIM: 225300,601906,617073) PREDICTE ( 267) 623 145.1 1.8e-34
XP_016875408 (OMIM: 225300,601906,617073) PREDICTE ( 267) 623 145.1 1.8e-34
NP_003385 (OMIM: 225300,601906,617073) protein Wnt ( 389) 623 145.2 2.4e-34
NP_490645 (OMIM: 606360) protein Wnt-8a isoform 3 ( 351) 615 143.4 7.5e-34
NP_001287868 (OMIM: 606360) protein Wnt-8a isoform ( 369) 615 143.4 7.8e-34
NP_001287867 (OMIM: 606360) protein Wnt-8a isoform ( 386) 615 143.4 8.1e-34
XP_016865314 (OMIM: 606360) PREDICTED: protein Wnt ( 391) 615 143.4 8.2e-34
XP_016865313 (OMIM: 606360) PREDICTED: protein Wnt ( 408) 615 143.4 8.5e-34
XP_011541927 (OMIM: 606360) PREDICTED: protein Wnt ( 337) 606 141.4 2.8e-33
NP_003384 (OMIM: 601396) protein Wnt-8b precursor ( 351) 601 140.3 6.3e-33
XP_011542573 (OMIM: 602863) PREDICTED: protein Wnt ( 295) 597 139.4 1e-32
>>NP_476509 (OMIM: 606267) protein Wnt-16 isoform 1 prec (365 aa)
initn: 2594 init1: 2594 opt: 2594 Z-score: 3064.6 bits: 575.7 E(85289): 5.8e-164
Smith-Waterman score: 2594; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KE1 MDRAALLGLARLCALWAALLVLFPYGAQGNWMWLGIASFGVPEKLGCANLPLNSRQKELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 MDRAALLGLARLCALWAALLVLFPYGAQGNWMWLGIASFGVPEKLGCANLPLNSRQKELC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 KRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYELSSGTKET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 KRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYELSSGTKET
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 AFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQYGMWFSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 AFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQYGMWFSR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 KFLDFPIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 KFLDFPIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 SFEKIGHLLKDKYENSIQISDKTKRKMRRREKDQRKIPIHKDDLLYVNKSPNYCVEDKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 SFEKIGHLLKDKYENSIQISDKTKRKMRRREKDQRKIPIHKDDLLYVNKSPNYCVEDKKL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 GIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 GIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTD
310 320 330 340 350 360
pF1KE1 VHTCK
:::::
NP_476 VHTCK
>>NP_057171 (OMIM: 606267) protein Wnt-16 isoform 2 [Hom (355 aa)
initn: 2371 init1: 2371 opt: 2375 Z-score: 2806.2 bits: 527.8 E(85289): 1.4e-149
Smith-Waterman score: 2375; 97.4% identity (98.3% similar) in 346 aa overlap (22-365:11-355)
10 20 30 40 50
pF1KE1 MDRAALLGLARLCALWAALLVLFPYGAQGN--WMWLGIASFGVPEKLGCANLPLNSRQKE
:: ..: . : ::::::::::::::::::::::::::
NP_057 MQLTTCLRETLFTGASQKTSLW-WLGIASFGVPEKLGCANLPLNSRQKE
10 20 30 40
60 70 80 90 100 110
pF1KE1 LCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYELSSGTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYELSSGTK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 ETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQYGMWF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQYGMWF
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 SRKFLDFPIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SRKFLDFPIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKT
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 MSSFEKIGHLLKDKYENSIQISDKTKRKMRRREKDQRKIPIHKDDLLYVNKSPNYCVEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MSSFEKIGHLLKDKYENSIQISDKTKRKMRRREKDQRKIPIHKDDLLYVNKSPNYCVEDK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 KLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESM
290 300 310 320 330 340
360
pF1KE1 TDVHTCK
:::::::
NP_057 TDVHTCK
350
>>NP_478679 (OMIM: 601967) protein Wnt-7b precursor [Hom (349 aa)
initn: 783 init1: 644 opt: 1131 Z-score: 1337.9 bits: 256.1 E(85289): 8.8e-68
Smith-Waterman score: 1131; 48.5% identity (70.6% similar) in 326 aa overlap (47-365:38-349)
20 30 40 50 60 70
pF1KE1 AALLVLFPYGAQGNWMWLGIASFGVPEKLGCANLP-LNSRQKELCKRKPYLLPSIREGAR
: ..: : ::. .:. .: . : :::.
NP_478 WIFYVFLCFGVLYVKLGALSSVVALGANIICNKIPGLAPRQRAICQSRPDAIIVIGEGAQ
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE1 LGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYELSSGTKETAFIYAVMAAGLVHSV
.::.:: ::: :::: . .: . .:: :: :..:.:: ::. :::..:.:
NP_478 MGINECQYQFRFGRWNC--------SALGEKTVFGQELRVGSREAAFTYAITAAGVAHAV
70 80 90 100 110
140 150 160 170 180 190
pF1KE1 TRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQYGMWFSRKFLDFPIGNTTGKEN
: .:: ::...:.:: :. . .:::.::::: ::.::. :::.:.: :.:
NP_478 TAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDFSRRFVD----AREIKKN
120 130 140 150 160 170
200 210 220 230 240 250
pF1KE1 KVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKTMSSFEKIGHLLKDKYEN
: ::::::::::... :...:.::::::::..:::: :. .:...:::::.::.
NP_478 ARRL-MNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNA
180 190 200 210 220 230
260 270 280 290 300
pF1KE1 SIQISDKTKRKMRR----REKDQRKI--PIHKDDLLYVNKSPNYCVEDKKLGIPGTQGRE
..:. ..:. : :. :. :. . ::.:..:::::: :: : :::::
NP_478 AVQVEVVRASRLRQPTFLRIKQLRSYQKPM-ETDLVYIEKSPNYCEEDAATGSVGTQGRL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE1 CNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDVHTCK
::::: :::::. .::::::::: .: .:.::: :::.:.: : :.: :::
NP_478 CNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTCK
300 310 320 330 340
>>XP_011528668 (OMIM: 601967) PREDICTED: protein Wnt-7b (353 aa)
initn: 783 init1: 644 opt: 1131 Z-score: 1337.8 bits: 256.1 E(85289): 8.9e-68
Smith-Waterman score: 1135; 46.0% identity (70.5% similar) in 352 aa overlap (22-365:18-353)
10 20 30 40 50
pF1KE1 MDRAALLGLARLCALWAALLVLFPYGAQGNWMWLG-IASFGVPEKLGCANLP-LNSRQKE
.: ..:... :. ....:. .. : ..: : ::.
XP_011 MLLLSPRSALVSVYCPQIFLLLSSGSYLALSSVVALGA--NIICNKIPGLAPRQRA
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 LCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYELSSGTK
.:. .: . : :::..::.:: ::: :::: . .: . .:: :: :..
XP_011 ICQSRPDAIIVIGEGAQMGINECQYQFRFGRWNC--------SALGEKTVFGQELRVGSR
60 70 80 90 100
120 130 140 150 160 170
pF1KE1 ETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQYGMWF
:.:: ::. :::..:.:: .:: ::...:.:: :. . .:::.::::: ::.::. :
XP_011 EAAFTYAITAAGVAHAVTAACSQGNLSNCGCDREKQGYYNQAEGWKWGGCSADVRYGIDF
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 SRKFLDFPIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCWKT
::.:.: :.: : ::::::::::... :...:.::::::::..:::: :
XP_011 SRRFVD----AREIKKNARRL-MNLHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTT
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 MSSFEKIGHLLKDKYENSIQISDKTKRKMRR----REKDQRKI--PIHKDDLLYVNKSPN
. .:...:::::.::. ..:. ..:. : :. :. :. . ::.:..::::
XP_011 LPKFREVGHLLKEKYNAAVQVEVVRASRLRQPTFLRIKQLRSYQKPM-ETDLVYIEKSPN
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 YCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRC
:: :: : ::::: ::::: :::::. .::::::::: .: .:.::: :::.:.:
XP_011 YCEEDAATGSVGTQGRLCNRTSPGADGCDTMCCGRGYNTHQYTKVWQCNCKFHWCCFVKC
290 300 310 320 330 340
360
pF1KE1 RRCESMTDVHTCK
: :.: :::
XP_011 NTCSERTEVFTCK
350
>>NP_004616 (OMIM: 228930,276820,601570) protein Wnt-7a (349 aa)
initn: 757 init1: 624 opt: 1083 Z-score: 1281.2 bits: 245.6 E(85289): 1.3e-64
Smith-Waterman score: 1083; 43.2% identity (70.7% similar) in 345 aa overlap (32-365:19-349)
10 20 30 40 50
pF1KE1 DRAALLGLARLCALWAALLVLFPYGAQGNWMWLGIASFGVPEKLG----CANLP-LNSRQ
..: :..:. :: : ..: : ::
NP_004 MNRKARRCLGHLFLSLGMVYLRIGGFSSVVALGASIICNKIPGLAPRQ
10 20 30 40
60 70 80 90 100 110
pF1KE1 KELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYELSSG
. .:. .: . : ::...:..:: :::. :::: . .: .:: ::. :
NP_004 RAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNC--------SALGERTVFGKELKVG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 TKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQYGM
..:.:: ::..:::..:..: .:. ::...:.:: :. .:::.::::: :..::.
NP_004 SREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKWGGCSADIRYGI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 WFSRKFLDFPIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSCAVKTCW
:.. :.: :.: : ::::::::::. . . :...:.::::::::..::::
NP_004 GFAKVFVD----AREIKQNARTL-MNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCW
170 180 190 200 210
240 250 260 270 280 290
pF1KE1 KTMSSFEKIGHLLKDKYENSIQI----SDKTKRK--MRRREKDQRKIPIHKDDLLYVNKS
:. .:...:..:::::...... ....:: .. .. . . :. : :.:..::
NP_004 TTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDTD-LVYIEKS
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE1 PNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYV
:::: :: : ::::: ::.:. :.::.:.::::::::: .: .:.::: :::::
NP_004 PNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYV
280 290 300 310 320 330
360
pF1KE1 RCRRCESMTDVHTCK
.: : :...:::
NP_004 KCNTCSERTEMYTCK
340
>>NP_110402 (OMIM: 606361) protein Wnt-5b precursor [Hom (359 aa)
initn: 1038 init1: 417 opt: 1037 Z-score: 1226.7 bits: 235.6 E(85289): 1.4e-61
Smith-Waterman score: 1037; 42.1% identity (67.5% similar) in 375 aa overlap (1-365:1-359)
10 20 30 40 50
pF1KE1 MDRAALLGLARLCALWAALLVLFPYGAQGNWMWLGIASFGVPEK--LG----CANLP-LN
: :: : : . :: ::. ..: :.. :: .: :..:: :.
NP_110 MPSLLLLFTAALLSSWAQLLT-----DANSWWSLALNPVQRPEMFIIGAQPVCSQLPGLS
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 SRQKELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYEL
:..::. . : :::. ::.:: :::..:::: .:: .:: .:: .
NP_110 PGQRKLCQLYQEHMAYIGEGAKTGIKECQHQFRQRRWNC------STAD-NAS-VFGRVM
60 70 80 90 100
120 130 140 150 160 170
pF1KE1 SSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQ
. :..:::: .:: :::.:....:.: :... :.:. : . . . : ::::.:.:.
NP_110 QIGSRETAFTHAVSAAGVVNAISRACREGELSTCGCSRTARPK-DLPRDWLWGGCGDNVE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 YGMWFSRKFLDF---PIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSC
::. :...:.: . . :.:.. . :::.::::::.:: :. .: :.::::::::
NP_110 YGYRFAKEFVDAREREKNFAKGSEEQGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSC
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 AVKTCWKTMSSFEKIGHLLKDKYENSIQISDKTKRKMRRREKDQRKIPIHKDDLLYVNKS
..:::: .. :.:.: ::.::... . .. :: : . ..: .::.::. :
NP_110 SLKTCWLQLAEFRKVGDRLKEKYDSAAAM--RVTRKGRLELVNSRFTQPTPEDLVYVDPS
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 PNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYV
:.::..... : ::::: ::.:::: :::.:.::::::: .::::.::: :::.:
NP_110 PDYCLRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFV
290 300 310 320 330 340
360
pF1KE1 RCRRCESMTDVHTCK
::..: ..: . ::
NP_110 RCKKCTEIVDQYICK
350
>>NP_116031 (OMIM: 606361) protein Wnt-5b precursor [Hom (359 aa)
initn: 1038 init1: 417 opt: 1037 Z-score: 1226.7 bits: 235.6 E(85289): 1.4e-61
Smith-Waterman score: 1037; 42.1% identity (67.5% similar) in 375 aa overlap (1-365:1-359)
10 20 30 40 50
pF1KE1 MDRAALLGLARLCALWAALLVLFPYGAQGNWMWLGIASFGVPEK--LG----CANLP-LN
: :: : : . :: ::. ..: :.. :: .: :..:: :.
NP_116 MPSLLLLFTAALLSSWAQLLT-----DANSWWSLALNPVQRPEMFIIGAQPVCSQLPGLS
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 SRQKELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYEL
:..::. . : :::. ::.:: :::..:::: .:: .:: .:: .
NP_116 PGQRKLCQLYQEHMAYIGEGAKTGIKECQHQFRQRRWNC------STAD-NAS-VFGRVM
60 70 80 90 100
120 130 140 150 160 170
pF1KE1 SSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGGCSDDVQ
. :..:::: .:: :::.:....:.: :... :.:. : . . . : ::::.:.:.
NP_116 QIGSRETAFTHAVSAAGVVNAISRACREGELSTCGCSRTARPK-DLPRDWLWGGCGDNVE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE1 YGMWFSRKFLDF---PIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSC
::. :...:.: . . :.:.. . :::.::::::.:: :. .: :.::::::::
NP_116 YGYRFAKEFVDAREREKNFAKGSEEQGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSC
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE1 AVKTCWKTMSSFEKIGHLLKDKYENSIQISDKTKRKMRRREKDQRKIPIHKDDLLYVNKS
..:::: .. :.:.: ::.::... . .. :: : . ..: .::.::. :
NP_116 SLKTCWLQLAEFRKVGDRLKEKYDSAAAM--RVTRKGRLELVNSRFTQPTPEDLVYVDPS
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE1 PNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYV
:.::..... : ::::: ::.:::: :::.:.::::::: .::::.::: :::.:
NP_116 PDYCLRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFV
290 300 310 320 330 340
360
pF1KE1 RCRRCESMTDVHTCK
::..: ..: . ::
NP_116 RCKKCTEIVDQYICK
350
>>XP_011532393 (OMIM: 228930,276820,601570) PREDICTED: p (282 aa)
initn: 699 init1: 624 opt: 1009 Z-score: 1195.2 bits: 229.4 E(85289): 7.8e-60
Smith-Waterman score: 1009; 45.3% identity (72.6% similar) in 296 aa overlap (76-365:1-282)
50 60 70 80 90 100
pF1KE1 GCANLPLNSRQKELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGA
.:..:: :::. :::: . .:
XP_011 MGLDECQFQFRNGRWNC--------SALGE
10 20
110 120 130 140 150 160
pF1KE1 SPLFGYELSSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHW
.:: ::. :..:.:: ::..:::..:..: .:. ::...:.:: :. .:::.:
XP_011 RTVFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQGQYHRDEGWKW
30 40 50 60 70 80
170 180 190 200 210 220
pF1KE1 GGCSDDVQYGMWFSRKFLDFPIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHG
:::: :..::. :.. :.: :.: : ::::::::::. . . :...:.:::
XP_011 GGCSADIRYGIGFAKVFVD----AREIKQNARTL-MNLHNNEAGRKILEENMKLECKCHG
90 100 110 120 130
230 240 250 260 270
pF1KE1 VSGSCAVKTCWKTMSSFEKIGHLLKDKYENSIQI----SDKTKRK--MRRREKDQRKIPI
:::::..:::: :. .:...:..:::::...... ....:: .. .. . . :.
XP_011 VSGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPM
140 150 160 170 180 190
280 290 300 310 320 330
pF1KE1 HKDDLLYVNKSPNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVER
: :.:..:::::: :: : ::::: ::.:. :.::.:.::::::::: .: .
XP_011 DTD-LVYIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQ
200 210 220 230 240 250
340 350 360
pF1KE1 CECKFIWCCYVRCRRCESMTDVHTCK
:.::: :::::.: : :...:::
XP_011 CNCKFHWCCYVKCNTCSERTEMYTCK
260 270 280
>>XP_016862617 (OMIM: 164975,180700) PREDICTED: protein (365 aa)
initn: 1004 init1: 401 opt: 990 Z-score: 1171.1 bits: 225.3 E(85289): 1.7e-58
Smith-Waterman score: 990; 39.3% identity (68.4% similar) in 364 aa overlap (18-365:14-365)
10 20 30 40
pF1KE1 MDRAALLGLARLCALWAALLVLFPYGAQ-----GNWMWLGIAS-------FGVPEKLGCA
:: ..: . :: ..: ::. . . . . :.
XP_016 MAGSAMSSKFFLVALAIFFSF-AQVVIEANSWWSLGMNNPVQMSEVYIIGAQPLCS
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 NLP-LNSRQKELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASP
.: :.. ::.::. . : :::. ::.:: ::::.:::: . . .
XP_016 QLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNC--------STVDNTS
60 70 80 90 100
110 120 130 140 150 160
pF1KE1 LFGYELSSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGG
.:: .. :..:::: ::: :::.:....:.: :... :.:. . . . . : :::
XP_016 VFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPK-DLPRDWLWGG
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE1 CSDDVQYGMWFSRKFLDF---PIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCH
:.:...::. :...:.: .. :. ... . ::::::::::..: .: .: :.::
XP_016 CGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKCH
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 GVSGSCAVKTCWKTMSSFEKIGHLLKDKYENSIQISDKTKRKMRRREKDQRKIPIHKDDL
::::::..:::: ...:.:.: ::.::... . ... :. . ..: .::
XP_016 GVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKL--VQVNSRFNSPTTQDL
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 LYVNKSPNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKF
.:.. ::.:::.... : ::::: ::.:::: :::.:.::::::. . ..:::.:::
XP_016 VYIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKF
290 300 310 320 330 340
350 360
pF1KE1 IWCCYVRCRRCESMTDVHTCK
:::::.:..: ..: .::
XP_016 HWCCYVKCKKCTEIVDQFVCK
350 360
>>XP_011532389 (OMIM: 164975,180700) PREDICTED: protein (365 aa)
initn: 1004 init1: 401 opt: 990 Z-score: 1171.1 bits: 225.3 E(85289): 1.7e-58
Smith-Waterman score: 990; 39.3% identity (68.4% similar) in 364 aa overlap (18-365:14-365)
10 20 30 40
pF1KE1 MDRAALLGLARLCALWAALLVLFPYGAQ-----GNWMWLGIAS-------FGVPEKLGCA
:: ..: . :: ..: ::. . . . . :.
XP_011 MAGSAMSSKFFLVALAIFFSF-AQVVIEANSWWSLGMNNPVQMSEVYIIGAQPLCS
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 NLP-LNSRQKELCKRKPYLLPSIREGARLGIQECGSQFRHERWNCMITAAATTAPMGASP
.: :.. ::.::. . : :::. ::.:: ::::.:::: . . .
XP_011 QLAGLSQGQKKLCHLYQDHMQYIGEGAKTGIKECQYQFRHRRWNC--------STVDNTS
60 70 80 90 100
110 120 130 140 150 160
pF1KE1 LFGYELSSGTKETAFIYAVMAAGLVHSVTRSCSAGNMTECSCDTTLQNGGSASEGWHWGG
.:: .. :..:::: ::: :::.:....:.: :... :.:. . . . . : :::
XP_011 VFGRVMQIGSRETAFTYAVSAAGVVNAMSRACREGELSTCGCSRAARPK-DLPRDWLWGG
110 120 130 140 150 160
170 180 190 200 210 220
pF1KE1 CSDDVQYGMWFSRKFLDF---PIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCH
:.:...::. :...:.: .. :. ... . ::::::::::..: .: .: :.::
XP_011 CGDNIDYGYRFAKEFVDARERERIHAKGSYESARILMNLHNNEAGRRTVYNLADVACKCH
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE1 GVSGSCAVKTCWKTMSSFEKIGHLLKDKYENSIQISDKTKRKMRRREKDQRKIPIHKDDL
::::::..:::: ...:.:.: ::.::... . ... :. . ..: .::
XP_011 GVSGSCSLKTCWLQLADFRKVGDALKEKYDSAAAMRLNSRGKL--VQVNSRFNSPTTQDL
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE1 LYVNKSPNYCVEDKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKF
.:.. ::.:::.... : ::::: ::.:::: :::.:.::::::. . ..:::.:::
XP_011 VYIDPSPDYCVRNESTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKTVQTERCHCKF
290 300 310 320 330 340
350 360
pF1KE1 IWCCYVRCRRCESMTDVHTCK
:::::.:..: ..: .::
XP_011 HWCCYVKCKKCTEIVDQFVCK
350 360
365 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 16:18:47 2016 done: Sun Nov 6 16:18:48 2016
Total Scan time: 7.670 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]