Result of FASTA (omim) for
pFN21AE5247
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5247, 222 aa
1>>>pF1KE5247 222 - 222 aa - 222 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7902+/-0.000305; mu= 17.0807+/- 0.019
mean_var=61.9970+/-12.365, 0's: 0 Z-trim(116.2): 34 B-trim: 0 in 0/55
Lambda= 0.162888
statistics sampled from 27181 (27215) to 27181 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.319), width: 16
Scan time: 6.700
The best scores are: opt bits E(85289)
NP_665683 (OMIM: 138359) glutathione S-transferase ( 222) 1437 345.7 3.7e-95
NP_000837 (OMIM: 138360) glutathione S-transferase ( 222) 1361 327.8 8.8e-90
XP_011512834 (OMIM: 138360) PREDICTED: glutathione ( 222) 1361 327.8 8.8e-90
NP_000838 (OMIM: 605449) glutathione S-transferase ( 222) 1297 312.8 3e-85
NP_714543 (OMIM: 607605) glutathione S-transferase ( 222) 1287 310.4 1.5e-84
XP_005249091 (OMIM: 138359) PREDICTED: glutathione ( 225) 1174 283.9 1.5e-76
XP_016866283 (OMIM: 605449) PREDICTED: glutathione ( 172) 1020 247.6 9.6e-66
XP_006715135 (OMIM: 605449) PREDICTED: glutathione ( 172) 1020 247.6 9.6e-66
XP_005249092 (OMIM: 605450) PREDICTED: glutathione ( 222) 842 205.8 4.6e-53
NP_001503 (OMIM: 605450) glutathione S-transferase ( 222) 842 205.8 4.6e-53
NP_001305988 (OMIM: 138359) glutathione S-transfer ( 129) 834 203.8 1.1e-52
XP_011512835 (OMIM: 605449) PREDICTED: glutathione ( 129) 747 183.3 1.6e-46
XP_011512837 (OMIM: 605450) PREDICTED: glutathione ( 185) 636 157.4 1.5e-38
XP_011512836 (OMIM: 605450) PREDICTED: glutathione ( 185) 636 157.4 1.5e-38
NP_000843 (OMIM: 134660) glutathione S-transferase ( 210) 293 76.8 3e-14
NP_055300 (OMIM: 602598) hematopoietic prostagland ( 199) 242 64.8 1.2e-10
NP_000840 (OMIM: 138390) glutathione S-transferase ( 225) 208 56.9 3.3e-08
NP_000839 (OMIM: 138380) glutathione S-transferase ( 218) 203 55.7 7.2e-08
NP_000841 (OMIM: 138333) glutathione S-transferase ( 218) 197 54.3 1.9e-07
NP_000552 (OMIM: 138350) glutathione S-transferase ( 218) 195 53.8 2.6e-07
NP_001135840 (OMIM: 138380) glutathione S-transfer ( 191) 188 52.1 7.5e-07
NP_665877 (OMIM: 603758) maleylacetoacetate isomer ( 216) 184 51.2 1.6e-06
NP_671489 (OMIM: 138333) glutathione S-transferase ( 195) 181 50.5 2.4e-06
XP_016856574 (OMIM: 138333) PREDICTED: glutathione ( 254) 181 50.6 2.9e-06
NP_000842 (OMIM: 138385) glutathione S-transferase ( 218) 170 47.9 1.6e-05
XP_005270841 (OMIM: 138385) PREDICTED: glutathione ( 218) 170 47.9 1.6e-05
NP_001299589 (OMIM: 603758) maleylacetoacetate iso ( 161) 164 46.4 3.3e-05
XP_016856576 (OMIM: 138333) PREDICTED: glutathione ( 177) 157 44.8 0.00011
XP_005270839 (OMIM: 138350) PREDICTED: glutathione ( 184) 157 44.8 0.00011
NP_666533 (OMIM: 138350) glutathione S-transferase ( 181) 151 43.4 0.0003
XP_016856575 (OMIM: 138333) PREDICTED: glutathione ( 213) 141 41.1 0.0017
>>NP_665683 (OMIM: 138359) glutathione S-transferase A1 (222 aa)
initn: 1437 init1: 1437 opt: 1437 Z-score: 1829.4 bits: 345.7 E(85289): 3.7e-95
Smith-Waterman score: 1437; 100.0% identity (100.0% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE5 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE5 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
::::::::::::::::::::::::::::::::::::::::::
NP_665 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
190 200 210 220
>>NP_000837 (OMIM: 138360) glutathione S-transferase A2 (222 aa)
initn: 1361 init1: 1361 opt: 1361 Z-score: 1732.9 bits: 327.8 E(85289): 8.8e-90
Smith-Waterman score: 1361; 95.0% identity (96.8% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE5 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
::::::::: : :::::: :::::::::::::::::::::::::::::::::::::::::
NP_000 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
::::::::::::::::::::::::::::.::::::::::::::::::::: :::.:::
NP_000 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
::::.:: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE5 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
:::::::::::::::::::::::::::::::::::.::::::
NP_000 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
190 200 210 220
>>XP_011512834 (OMIM: 138360) PREDICTED: glutathione S-t (222 aa)
initn: 1361 init1: 1361 opt: 1361 Z-score: 1732.9 bits: 327.8 E(85289): 8.8e-90
Smith-Waterman score: 1361; 95.0% identity (96.8% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE5 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
::::::::: : :::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
::::::::::::::::::::::::::::.::::::::::::::::::::: :::.:::
XP_011 DGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
::::.:: ::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE5 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
:::::::::::::::::::::::::::::::::::.::::::
XP_011 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
190 200 210 220
>>NP_000838 (OMIM: 605449) glutathione S-transferase A3 (222 aa)
initn: 1297 init1: 1297 opt: 1297 Z-score: 1651.6 bits: 312.8 E(85289): 3e-85
Smith-Waterman score: 1297; 90.5% identity (94.6% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE5 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
:: ::::::::.::::: :::::::::::::::: ::::: :::::: :::::::::::
NP_000 MAGKPKLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
::::::::::::::::::::::::::::::::::: ::.:::.:::::::.: :::::::
NP_000 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
.:::::: :.::::::::::.::::::::::::::::: :::::::::::::::::.:::
NP_000 IALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPL
130 140 150 160 170 180
190 200 210 220
pF1KE5 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
::::::::::::::::::::::::::: : :.::::::::::
NP_000 LKALKTRISNLPTVKKFLQPGSPRKPPADAKALEEARKIFRF
190 200 210 220
>>NP_714543 (OMIM: 607605) glutathione S-transferase A5 (222 aa)
initn: 1287 init1: 1287 opt: 1287 Z-score: 1638.9 bits: 310.4 E(85289): 1.5e-84
Smith-Waterman score: 1287; 90.1% identity (94.6% similar) in 222 aa overlap (1-222:1-222)
10 20 30 40 50 60
pF1KE5 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
::::::::: :::: ::: ::::::::::.::::..:::::::::::: :.:::::::::
NP_714 MAEKPKLHYSNARGSMESIRWLLAAAGVELEEKFLESAEDLDKLRNDGSLLFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
:::::::::::::::::::::::::.::::::::: :::.:: :::::: .: :::.:::
NP_714 DGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
::.::::::::::::::::::: :::::::::: ::::::::.::::::::::::::::
NP_714 TALVKEKIKNRYFPAFEKVLKSHRQDYLVGNKLSWADIHLVELFYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE5 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
:::::::::::::::::::::: :::::::::::::::::::
NP_714 LKALKTRISNLPTVKKFLQPGSQRKPPMDEKSLEEARKIFRF
190 200 210 220
>>XP_005249091 (OMIM: 138359) PREDICTED: glutathione S-t (225 aa)
initn: 1192 init1: 1174 opt: 1174 Z-score: 1495.3 bits: 283.9 E(85289): 1.5e-76
Smith-Waterman score: 1177; 90.8% identity (93.7% similar) in 206 aa overlap (1-206:1-196)
10 20 30 40 50 60
pF1KE5 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
130 140 150 160 170 180
190 200 210 220
pF1KE5 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
:: .... . : ::: .:
XP_005 LK-----VTHFTA-----QRGSPTSPILGSCIWALRLTKFCPSLLQAFSAPRSPK
190 200 210 220
>>XP_016866283 (OMIM: 605449) PREDICTED: glutathione S-t (172 aa)
initn: 1020 init1: 1020 opt: 1020 Z-score: 1301.3 bits: 247.6 E(85289): 9.6e-66
Smith-Waterman score: 1020; 91.9% identity (96.5% similar) in 172 aa overlap (51-222:1-172)
30 40 50 60 70 80
pF1KE5 WLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYN
::::::::::::::::::::::::::::::
XP_016 MFQQVPMVEIDGMKLVQTRAILNYIASKYN
10 20 30
90 100 110 120 130 140
pF1KE5 LYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIKEKIKNRYFPAFEKVL
::::::::::::::: ::.:::.:::::::.: :::::::.:::::: :.::::::::::
XP_016 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE5 KSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQP
.::::::::::::::::: :::::::::::::::::.:::::::::::::::::::::::
XP_016 QSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQP
100 110 120 130 140 150
210 220
pF1KE5 GSPRKPPMDEKSLEEARKIFRF
::::::: : :.::::::::::
XP_016 GSPRKPPADAKALEEARKIFRF
160 170
>>XP_006715135 (OMIM: 605449) PREDICTED: glutathione S-t (172 aa)
initn: 1020 init1: 1020 opt: 1020 Z-score: 1301.3 bits: 247.6 E(85289): 9.6e-66
Smith-Waterman score: 1020; 91.9% identity (96.5% similar) in 172 aa overlap (51-222:1-172)
30 40 50 60 70 80
pF1KE5 WLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYN
::::::::::::::::::::::::::::::
XP_006 MFQQVPMVEIDGMKLVQTRAILNYIASKYN
10 20 30
90 100 110 120 130 140
pF1KE5 LYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIKEKIKNRYFPAFEKVL
::::::::::::::: ::.:::.:::::::.: :::::::.:::::: :.::::::::::
XP_006 LYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE5 KSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQP
.::::::::::::::::: :::::::::::::::::.:::::::::::::::::::::::
XP_006 QSHGQDYLVGNKLSRADISLVELLYYVEELDSSLISNFPLLKALKTRISNLPTVKKFLQP
100 110 120 130 140 150
210 220
pF1KE5 GSPRKPPMDEKSLEEARKIFRF
::::::: : :.::::::::::
XP_006 GSPRKPPADAKALEEARKIFRF
160 170
>>XP_005249092 (OMIM: 605450) PREDICTED: glutathione S-t (222 aa)
initn: 842 init1: 842 opt: 842 Z-score: 1073.7 bits: 205.8 E(85289): 4.6e-53
Smith-Waterman score: 842; 53.8% identity (84.2% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KE5 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
:: .::::: :.::::::.::.::::::::.:.:... :.: ::.. ..:.:::::::::
XP_005 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
:::::::::.::.:::.:.::.::..:::.:::::.:: :: :.... : :.... .
XP_005 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
.. . .: ::::.:::.:..:::..::::.:: ::. :.. . .:: ...:.::.
XP_005 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF
130 140 150 160 170 180
190 200 210 220
pF1KE5 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
:. ...::.::.:.::.::: .::: :: .. . .:::
XP_005 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
190 200 210 220
>>NP_001503 (OMIM: 605450) glutathione S-transferase A4 (222 aa)
initn: 842 init1: 842 opt: 842 Z-score: 1073.7 bits: 205.8 E(85289): 4.6e-53
Smith-Waterman score: 842; 53.8% identity (84.2% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KE5 MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
:: .::::: :.::::::.::.::::::::.:.:... :.: ::.. ..:.:::::::::
NP_001 MAARPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLLFQQVPMVEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
:::::::::.::.:::.:.::.::..:::.:::::.:: :: :.... : :.... .
NP_001 DGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPFLKPDDQQKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
.. . .: ::::.:::.:..:::..::::.:: ::. :.. . .:: ...:.::.
NP_001 VVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQTILALEEKIPNILSAFPF
130 140 150 160 170 180
190 200 210 220
pF1KE5 LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
:. ...::.::.:.::.::: .::: :: .. . .:::
NP_001 LQEYTVKLSNIPTIKRFLEPGSKKKPPPDEIYVRTVYNIFRP
190 200 210 220
222 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:51:16 2016 done: Mon Nov 7 22:51:17 2016
Total Scan time: 6.700 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]