Result of FASTA (omim) for
pFN21AB9739
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9739, 507 aa
1>>>pF1KB9739 507 - 507 aa - 507 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.7846+/-0.000359; mu= -6.4107+/- 0.022
mean_var=306.6107+/-63.843, 0's: 0 Z-trim(123.2): 62 B-trim: 1059 in 2/60
Lambda= 0.073245
statistics sampled from 42453 (42523) to 42453 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.499), width: 16
Scan time: 8.520
The best scores are: opt bits E(85289)
NP_001019801 (OMIM: 119600,156510,600211) runt-rel ( 521) 3409 373.6 7.6e-103
XP_011513263 (OMIM: 119600,156510,600211) PREDICTE ( 589) 3409 373.7 8.3e-103
XP_011513266 (OMIM: 119600,156510,600211) PREDICTE ( 508) 2640 292.4 2.2e-78
NP_001265407 (OMIM: 119600,156510,600211) runt-rel ( 485) 2247 250.8 6.6e-66
XP_016866881 (OMIM: 119600,156510,600211) PREDICTE ( 528) 2227 248.7 3e-65
NP_001015051 (OMIM: 119600,156510,600211) runt-rel ( 499) 2213 247.2 8.1e-65
XP_011513264 (OMIM: 119600,156510,600211) PREDICTE ( 567) 2213 247.3 9e-65
XP_016866880 (OMIM: 119600,156510,600211) PREDICTE ( 592) 2193 245.2 4e-64
XP_011513262 (OMIM: 119600,156510,600211) PREDICTE ( 610) 2193 245.2 4.1e-64
XP_016866882 (OMIM: 119600,156510,600211) PREDICTE ( 438) 2155 241.1 5.1e-63
XP_011513267 (OMIM: 119600,156510,600211) PREDICTE ( 416) 2151 240.6 6.6e-63
XP_006715295 (OMIM: 119600,156510,600211) PREDICTE ( 449) 1626 185.2 3.5e-46
XP_016866885 (OMIM: 119600,156510,600211) PREDICTE ( 276) 1444 165.8 1.5e-40
XP_011513265 (OMIM: 119600,156510,600211) PREDICTE ( 552) 1437 165.3 4.3e-40
XP_016866883 (OMIM: 119600,156510,600211) PREDICTE ( 358) 1410 162.3 2.2e-39
XP_016866884 (OMIM: 119600,156510,600211) PREDICTE ( 338) 1383 159.4 1.5e-38
XP_011513268 (OMIM: 119600,156510,600211) PREDICTE ( 386) 1287 149.3 1.9e-35
XP_016883976 (OMIM: 151385,601399) PREDICTED: runt ( 429) 1229 143.2 1.4e-33
NP_001001890 (OMIM: 151385,601399) runt-related tr ( 453) 1229 143.2 1.5e-33
XP_011528069 (OMIM: 151385,601399) PREDICTED: runt ( 467) 1229 143.2 1.5e-33
XP_005261125 (OMIM: 151385,601399) PREDICTED: runt ( 468) 1229 143.2 1.5e-33
NP_001745 (OMIM: 151385,601399) runt-related trans ( 480) 1229 143.2 1.6e-33
XP_011528068 (OMIM: 151385,601399) PREDICTED: runt ( 480) 1229 143.2 1.6e-33
NP_001116079 (OMIM: 151385,601399) runt-related tr ( 250) 1025 121.5 2.9e-27
XP_011528072 (OMIM: 151385,601399) PREDICTED: runt ( 277) 1025 121.5 3.1e-27
NP_004341 (OMIM: 600210) runt-related transcriptio ( 415) 1000 119.0 2.7e-26
XP_005246081 (OMIM: 600210) PREDICTED: runt-relate ( 429) 1000 119.0 2.8e-26
NP_001026850 (OMIM: 600210) runt-related transcrip ( 429) 1000 119.0 2.8e-26
NP_001307601 (OMIM: 600210) runt-related transcrip ( 429) 1000 119.0 2.8e-26
XP_011528070 (OMIM: 151385,601399) PREDICTED: runt ( 403) 924 111.0 6.9e-24
XP_005261126 (OMIM: 151385,601399) PREDICTED: runt ( 416) 924 111.0 7.1e-24
XP_011540653 (OMIM: 600210) PREDICTED: runt-relate ( 376) 867 104.9 4.3e-22
XP_016858159 (OMIM: 600210) PREDICTED: runt-relate ( 162) 610 77.5 3.3e-14
>>NP_001019801 (OMIM: 119600,156510,600211) runt-related (521 aa)
initn: 3409 init1: 3409 opt: 3409 Z-score: 1967.4 bits: 373.6 E(85289): 7.6e-103
Smith-Waterman score: 3409; 100.0% identity (100.0% similar) in 502 aa overlap (6-507:20-521)
10 20 30 40
pF1KB9 MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQ
:::::::::::::::::::::::::::::::::::::::::
NP_001 MASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 QQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPN
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB9 FLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB9 RFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPS
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB9 LFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB9 QSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKS
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB9 QAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHT
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB9 YLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGS
430 440 450 460 470 480
470 480 490 500
pF1KB9 TLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
:::::::::::::::::::::::::::::::::::::::::
NP_001 TLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
490 500 510 520
>>XP_011513263 (OMIM: 119600,156510,600211) PREDICTED: r (589 aa)
initn: 3409 init1: 3409 opt: 3409 Z-score: 1966.7 bits: 373.7 E(85289): 8.3e-103
Smith-Waterman score: 3409; 100.0% identity (100.0% similar) in 502 aa overlap (6-507:88-589)
10 20 30
pF1KB9 MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
::::::::::::::::::::::::::::::
XP_011 YKFYLKKKGGTMASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB9 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB9 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB9 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB9 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR
300 310 320 330 340 350
280 290 300 310 320 330
pF1KB9 QAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDF
360 370 380 390 400 410
340 350 360 370 380 390
pF1KB9 CLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMS
420 430 440 450 460 470
400 410 420 430 440 450
pF1KB9 LGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRM
480 490 500 510 520 530
460 470 480 490 500
pF1KB9 LPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
540 550 560 570 580
>>XP_011513266 (OMIM: 119600,156510,600211) PREDICTED: r (508 aa)
initn: 2870 init1: 2640 opt: 2640 Z-score: 1528.4 bits: 292.4 E(85289): 2.2e-78
Smith-Waterman score: 2640; 99.5% identity (99.5% similar) in 395 aa overlap (6-400:88-482)
10 20 30
pF1KB9 MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
::::::::::::::::::::::::::::::
XP_011 YKFYLKKKGGTMASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB9 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB9 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB9 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB9 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR
300 310 320 330 340 350
280 290 300 310 320 330
pF1KB9 QAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDF
360 370 380 390 400 410
340 350 360 370 380 390
pF1KB9 CLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMS
420 430 440 450 460 470
400 410 420 430 440 450
pF1KB9 LGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRM
:: :
XP_011 LGHPALQDSVWGSWTCASCLGVSLGIHPDSF
480 490 500
>>NP_001265407 (OMIM: 119600,156510,600211) runt-related (485 aa)
initn: 2185 init1: 2185 opt: 2247 Z-score: 1304.2 bits: 250.8 E(85289): 6.6e-66
Smith-Waterman score: 3237; 95.7% identity (95.7% similar) in 507 aa overlap (1-507:1-485)
10 20 30 40 50 60
pF1KB9 MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 IHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKSQAGASELGPFSDPR
:::::::::::::::::::::::::: ::::::::::::
NP_001 IHSTTPLSSTRGTGLPAITDVPRRIS----------------------GASELGPFSDPR
310 320 330
370 380 390 400 410 420
pF1KB9 QFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQS
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB9 GPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGSTLLNPNLPNQNDGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGSTLLNPNLPNQNDGV
400 410 420 430 440 450
490 500
pF1KB9 DADGSHSSSPTVLNSSGRMDESVWRPY
:::::::::::::::::::::::::::
NP_001 DADGSHSSSPTVLNSSGRMDESVWRPY
460 470 480
>>XP_016866881 (OMIM: 119600,156510,600211) PREDICTED: r (528 aa)
initn: 2205 init1: 2205 opt: 2227 Z-score: 1292.3 bits: 248.7 E(85289): 3e-65
Smith-Waterman score: 2242; 74.3% identity (81.7% similar) in 498 aa overlap (1-485:1-469)
10 20 30 40 50 60
pF1KB9 MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 AAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 TLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPS
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 IHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKSQA----GASELGPF
:::::::::::::::::::::::::::.. ::::...:.. .. : ::
XP_016 IHSTTPLSSTRGTGLPAITDVPRRISDSE---------PSTLDSQSSTTLFLSSEEPGPS
310 320 330 340 350
360 370 380 390 400 410
pF1KB9 SDPRQFPSISSLTESRFS-NPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGS
. :: :: . :: .: :: ::. .. :: :: ::.
XP_016 TAALPSPSSSSCEPQAFSPGP----PALPPLLPPLPAA-----SA---------PPGPGA
360 370 380 390
420 430 440 450 460
pF1KB9 SQSQSGPFQT-SSTP-----YLYYGTSSGSYQFPMVPGGDRS-PSRMLPPCTTTSNGSTL
:. ..: ... .:.: . . . : : . : :. : .: : . . :
XP_016 SR-RTGRYSVVASSPEAAPRLVDWLPGCPSTISPSTRGDDKERPPPVLAP-AEGPERSRA
400 410 420 430 440 450
470 480 490 500
pF1KB9 LNPNLPNQNDG-VDADGSHSSSPTVLNSSGRMDESVWRPY
:. ....: ::: :
XP_016 PRPSTAGREEGTVDAGTSPPPRARPAAAASLEAHVGDILVELRTMNGHLDSIARALTKLA
460 470 480 490 500 510
>>NP_001015051 (OMIM: 119600,156510,600211) runt-related (499 aa)
initn: 2151 init1: 2151 opt: 2213 Z-score: 1284.7 bits: 247.2 E(85289): 8.1e-65
Smith-Waterman score: 3203; 95.6% identity (95.6% similar) in 502 aa overlap (6-507:20-499)
10 20 30 40
pF1KB9 MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQ
:::::::::::::::::::::::::::::::::::::::::
NP_001 MASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQ
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 QQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPN
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB9 FLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVA
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB9 RFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPS
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB9 LFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB9 QSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKS
::::::::::::::::::::::::::::::::::::::::
NP_001 QSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRIS--------------------
310 320 330 340
350 360 370 380 390 400
pF1KB9 QAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --GASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHT
350 360 370 380 390
410 420 430 440 450 460
pF1KB9 YLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGS
400 410 420 430 440 450
470 480 490 500
pF1KB9 TLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
:::::::::::::::::::::::::::::::::::::::::
NP_001 TLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
460 470 480 490
>>XP_011513264 (OMIM: 119600,156510,600211) PREDICTED: r (567 aa)
initn: 2151 init1: 2151 opt: 2213 Z-score: 1283.9 bits: 247.3 E(85289): 9e-65
Smith-Waterman score: 3203; 95.6% identity (95.6% similar) in 502 aa overlap (6-507:88-567)
10 20 30
pF1KB9 MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
::::::::::::::::::::::::::::::
XP_011 YKFYLKKKGGTMASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB9 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB9 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB9 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB9 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR
300 310 320 330 340 350
280 290 300 310 320 330
pF1KB9 QAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDF
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRIS---------
360 370 380 390 400
340 350 360 370 380 390
pF1KB9 CLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMS
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -------------GASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMS
410 420 430 440 450
400 410 420 430 440 450
pF1KB9 LGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRM
460 470 480 490 500 510
460 470 480 490 500
pF1KB9 LPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY
520 530 540 550 560
>>XP_016866880 (OMIM: 119600,156510,600211) PREDICTED: r (592 aa)
initn: 2171 init1: 2171 opt: 2193 Z-score: 1272.2 bits: 245.2 E(85289): 4e-64
Smith-Waterman score: 2208; 74.0% identity (81.5% similar) in 493 aa overlap (6-485:70-533)
10 20 30
pF1KB9 MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
::::::::::::::::::::::::::::::
XP_016 YKFYLKKKGGTMASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB9 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB9 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB9 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB9 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR
280 290 300 310 320 330
280 290 300 310 320 330
pF1KB9 QAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDF
::::::::::::::::::::::::::::::::::::::::::::::::::::..
XP_016 QAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDSE------
340 350 360 370 380 390
340 350 360 370 380 390
pF1KB9 CLWPSTLSKKSQA----GASELGPFSDPRQFPSISSLTESRFS-NPRMHYPATFTYTPPV
::::...:.. .. : :: . :: :: . :: .: :: ::.
XP_016 ---PSTLDSQSSTTLFLSSEEPGPSTAALPSPSSSSCEPQAFSPGP----PALPPLLPPL
400 410 420 430 440
400 410 420 430 440
pF1KB9 TSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQT-SSTP-----YLYYGTSSGSYQFPM
.. :: :: ::.:. ..: ... .:.: . . . : :
XP_016 PAA-----SA---------PPGPGASR-RTGRYSVVASSPEAAPRLVDWLPGCPSTISPS
450 460 470 480 490
450 460 470 480 490 500
pF1KB9 VPGGDRS-PSRMLPPCTTTSNGSTLLNPNLPNQNDG-VDADGSHSSSPTVLNSSGRMDES
. : :. : .: : . . : :. ....: ::: :
XP_016 TRGDDKERPPPVLAP-AEGPERSRAPRPSTAGREEGTVDAGTSPPPRARPAAAASLEAHV
500 510 520 530 540 550
pF1KB9 VWRPY
XP_016 GDILVELRTMNGHLDSIARALTKLASSLGPQPEPLPDVSDAN
560 570 580 590
>>XP_011513262 (OMIM: 119600,156510,600211) PREDICTED: r (610 aa)
initn: 2171 init1: 2171 opt: 2193 Z-score: 1272.0 bits: 245.2 E(85289): 4.1e-64
Smith-Waterman score: 2208; 74.0% identity (81.5% similar) in 493 aa overlap (6-485:88-551)
10 20 30
pF1KB9 MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
::::::::::::::::::::::::::::::
XP_011 YKFYLKKKGGTMASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB9 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB9 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB9 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB9 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR
300 310 320 330 340 350
280 290 300 310 320 330
pF1KB9 QAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDF
::::::::::::::::::::::::::::::::::::::::::::::::::::..
XP_011 QAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDSE------
360 370 380 390 400 410
340 350 360 370 380 390
pF1KB9 CLWPSTLSKKSQA----GASELGPFSDPRQFPSISSLTESRFS-NPRMHYPATFTYTPPV
::::...:.. .. : :: . :: :: . :: .: :: ::.
XP_011 ---PSTLDSQSSTTLFLSSEEPGPSTAALPSPSSSSCEPQAFSPGP----PALPPLLPPL
420 430 440 450 460
400 410 420 430 440
pF1KB9 TSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQT-SSTP-----YLYYGTSSGSYQFPM
.. :: :: ::.:. ..: ... .:.: . . . : :
XP_011 PAA-----SA---------PPGPGASR-RTGRYSVVASSPEAAPRLVDWLPGCPSTISPS
470 480 490 500
450 460 470 480 490 500
pF1KB9 VPGGDRS-PSRMLPPCTTTSNGSTLLNPNLPNQNDG-VDADGSHSSSPTVLNSSGRMDES
. : :. : .: : . . : :. ....: ::: :
XP_011 TRGDDKERPPPVLAP-AEGPERSRAPRPSTAGREEGTVDAGTSPPPRARPAAAASLEAHV
510 520 530 540 550 560
pF1KB9 VWRPY
XP_011 GDILVELRTMNGHLDSIARALTKLASSLGPQPEPLPDVSDAN
570 580 590 600 610
>>XP_016866882 (OMIM: 119600,156510,600211) PREDICTED: r (438 aa)
initn: 2151 init1: 2151 opt: 2155 Z-score: 1252.3 bits: 241.1 E(85289): 5.1e-63
Smith-Waterman score: 2155; 93.8% identity (94.9% similar) in 353 aa overlap (6-358:88-436)
10 20 30
pF1KB9 MRIPVDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
::::::::::::::::::::::::::::::
XP_016 YKFYLKKKGGTMASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQ
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB9 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADH
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB9 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELR
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB9 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB9 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPR
300 310 320 330 340 350
280 290 300 310 320 330
pF1KB9 QAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDF
::::::::::::::::::::::::::::::::::::::::::::::::::: : .:
XP_016 QAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISGHP-ALQD-
360 370 380 390 400 410
340 350 360 370 380 390
pF1KB9 CLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMS
.: : . : :.: :: :
XP_016 SVWGS-WTCASCLGVS-LGIHPDSF
420 430
507 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 16:49:32 2016 done: Sun Nov 6 16:49:33 2016
Total Scan time: 8.520 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]